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Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system




Title: Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system.
Abstract: The present invention contemplates monitoring the amplification of nucleic acid using chromophore-containing polynucleotides having at least two donor chromophores operatively linked to the polynucleotide by linker arms, such that the chromophores are positioned by linkage along the length of the polynucleotide at a donor-donor transfer distance, and at least one fluorescing acceptor chromophore operatively linked to the polynucleotide by a linker arm, such that the fluorescing acceptor chromophore is positioned by linkage at a donor-acceptor transfer distance from at least one of the donor chromophores, to form a photonic structure for collecting photonic energy and transferring the energy to an acceptor chromophore, and methods using the photonic structures. ...


- Irvine, CA, US
Inventor: Michael J. Heller
USPTO Applicaton #: #20070042386
Related Patent Categories: Chemistry: Molecular Biology And Microbiology, Measuring Or Testing Process Involving Enzymes Or Micro-organisms; Composition Or Test Strip Therefore; Processes Of Forming Such Composition Or Test Strip, Involving Nucleic Acid
The Patent Description & Claims data below is from USPTO Patent Application 20070042386, Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system.

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stats Patent Info
Application #
US 20070042386 A1
Publish Date
02/22/2007
Document #
File Date
12/31/1969
USPTO Class
Other USPTO Classes
International Class
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Drawings
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20070222|20070042386|hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system|The present invention contemplates monitoring the amplification of nucleic acid using chromophore-containing polynucleotides having at least two donor chromophores operatively linked to the polynucleotide by linker arms, such that the chromophores are positioned by linkage along the length of the polynucleotide at a donor-donor transfer distance, and at least one |
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