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11/15/07 - USPTO Class 514 |  56 views | #20070265263 | Prev - Next | About this Page  514 rss/xml feed  monitor keywords

Heterocyclic inhibitors of erk2 and uses thereof

USPTO Application #: 20070265263
Title: Heterocyclic inhibitors of erk2 and uses thereof
Abstract: wherein Z1 and Z2 are each independently nitrogen or CH and Ring A, TmR1, QR2, UnR3, and Sp are as described in the specification. The compounds are especially useful as inhibitors of ERK2 and for treating diseases in mammals that are alleviated by a protein kinase inhibitor, particularly diseases such as cancer, inflammatory disorders, restenosis, diabetes, and cardiovascular disease. Described herein are compounds that are useful as protein kinase inhibitors having the formula: (end of abstract)



Agent: Vertex Pharmaceuticals Inc. - Cambridge, MA, US
Inventors: Jingrong Cao, Jeremy Green, Michael Hale, Francois Maltais, Judy Straub, Oing Tang, Alex Aronov
USPTO Applicaton #: 20070265263 - Class: 514235500 (USPTO)

Related Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Designated Organic Active Ingredient Containing (doai), Heterocyclic Carbon Compounds Containing A Hetero Ring Having Chalcogen (i.e., O,s,se Or Te) Or Nitrogen As The Only Ring Hetero Atoms Doai, Hetero Ring Is Six-membered And Includes At Least Nitrogen And Oxygen As Ring Hetero Atoms (e.g., Monocyclic 1,2- And 1,3-oxazines, Etc.), Morpholines (i.e., Fully Hydrogenated 1,4- Oxazines), Additional Hetero Ring Attached Directly Or Indirectly To The Morpholine Ring By Nonionic Bonding, Ring Nitrogen In The Additional Hetero Ring

Heterocyclic inhibitors of erk2 and uses thereof description/claims


The Patent Description & Claims data below is from USPTO Patent Application 20070265263, Heterocyclic inhibitors of erk2 and uses thereof.

Brief Patent Description - Full Patent Description - Patent Application Claims
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