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05/31/07 - USPTO Class 424 | 48 views | #20070122434 | Prev - Next | About this Page

Heat shock genes and proteins from neisseria meningitidis, candida glabrata and aspergillus fumigatus

Title: Heat shock genes and proteins from neisseria meningitidis, candida glabrata and aspergillus fumigatus

Related Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Antigen, Epitope, Or Other Immunospecific Immunoeffector (e.g., Immunospecific Vaccine, Immunospecific Stimulator Of Cell-mediated Immunity, Immunospecific Tolerogen, Immunospecific Immunosuppressor, Etc.), Bacterium Or Component Thereof Or Substance Produced By Said Bacterium (e.g., Legionella, Borrelia, Anaplasma, Shigella, Etc.), Neisseria (e.g., Neisseria Gonorrhoeae, Etc.), Neisseria Meningitidis

Brief Patent Description - Full Patent Description - Patent Claims

The Patent Description & Claims data below is from USPTO Patent Application 20070122434, Heat shock genes and proteins from neisseria meningitidis, candida glabrata and aspergillus fumigatus.

1-102. (canceled)

103. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:15.

104. An isolated polypeptide comprising an amino acid sequence that (a) is at least 95% homologous to a protein sequence represented by SEQ ID NO:15, and (b) comprises a peptide of at least 8 contiguous amino acids of the protein sequence, wherein the peptide binds to a major histocompatibility complex molecule and elicits or enhances an immune response in a human.

105. The polypeptide of claim 104, wherein the amino acid sequence is at least 97% homologous to the protein sequence.

106. The polypeptide of claim 105, wherein the amino acid sequence is at least 98% homologous to the protein sequence.

107. An isolated polypeptide comprising a peptide of at least 8 contiguous amino acids of a protein sequence represented by SEQ ID NO:15, wherein the peptide binds to a major histocompatibility complex molecule and elicits or enhances an immune response in a human.

108. The isolated polypeptide of claim 103, wherein the polypeptide is fused to a heterologous polypeptide to create a fusion protein.

109. The isolated polypeptide of claim 104, wherein the polypeptide is fused to a heterologous polypeptide to create a fusion protein.

110. The isolated polypeptide of claim 107, wherein the polypeptide is fused to a heterologous polypeptide to create a fusion protein.

111. A pharmaceutically acceptable composition comprising the polypeptide of claim 103 and a carrier or diluent.

112. The composition of claim 111, formulated for systemic or parenteral administration.

113. The composition of claim 111, formulated for oral or intranasal administration.

114. A pharmaceutically acceptable composition comprising the polypeptide of claim 104 and a carrier or diluent.

115. The composition of claim 114, formulated for systemic or parenteral administration.

116. The composition of claim 114, formulated for oral or intranasal administration.

117. A pharmaceutically acceptable composition comprising the polypeptide of claim 107 and a carrier or diluent.

118. The composition of claim 117, formulated for systemic or parenteral administration.

119. The composition of claim 117, formulated for oral or intranasal administration.

120. A method of eliciting or enhancing an immune response in a mammal against Neisseria, the method comprising administering to the mammal the polypeptide of claim 103 in an amount effective to elicit or enhance the immune response.

121. A method of eliciting or enhancing an immune response in a mammal against Neisseria, the method comprising administering to the mammal the composition of claim 104 in an amount effective to elicit or enhance the immune response.

122. A method of eliciting or enhancing an immune response in a mammal against a heterologous polypeptide, the method comprising administering to the mammal the polypeptide of claim 107 in an amount effective to elicit or enhance an immune response against the heterologous polypeptide.

Brief Patent Description - Full Patent Description - Patent Claims

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