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10/04/07 | 51 views | #20070232789 | Prev - Next | USPTO Class 530 | About this Page  530 rss/xml feed  monitor keywords

Factor viii compositions and methods

USPTO Application #: 20070232789
Title: Factor viii compositions and methods
Abstract: The present invention provides methods of increasing the half-life and/or specific activity of factor VIII. More specifically, the invention provides methods of increasing the half-life and/or specific activity of factor VIII by substituting one or more amino acids in the A2 domain. It further provides methods for producing such factor VIII mutants. The invention also provides polynucleotides encoding the mutant factor VIII, and methods of treating hemophilia using the polypeptides and polynucleotides of the invention. (end of abstract)
Agent: Sughrue Mion, PLLC - Washington, DC, US
Inventors: Evgueni L. Saenko, Andrey G. Sarafanov, Natalya M. Ananyeva
USPTO Applicaton #: 20070232789 - Class: 530383000 (USPTO)
Related Patent Categories: Chemistry: Natural Resins Or Derivatives; Peptides Or Proteins; Lignins Or Reaction Products Thereof, Proteins, I.e., More Than 100 Amino Acid Residues, Blood Proteins Or Globulins, E.g., Proteoglycans, Platelet Factor 4, Thyroglobulin, Thyroxine, Etc., Blood Coagulation Factors And Fibrin, E.g., Thromboplastin, Etc., Blood Coagulation Factor Viii, Ahf
The Patent Description & Claims data below is from USPTO Patent Application 20070232789.
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Factor viii compositions and methods
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Production of anti-self antibodies from antibody segment repertoires and displayed on phage
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Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof

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