Drug, bio-affecting and body treating compositions inventions 05/06

20060110322 - Assay for vitamin b12 absorption and method of making labeled vitamin b12: The invention provides methods for labeling vitamin B12 with 14C, 13C, tritium, and deuterium. When radioisotopes are used, the invention provides for methods of labeling B12 with high specific activity. The invention also provides labeled vitamin B12 compositions made in accordance with the invention....

20060110323 - Method of imaging cell death in vivo: The present invention relates to a method and a kit for detecting cell death or another condition characterized by an increase in the extracellular level of phosphatidylserine in a mammalian subject. The method involves administering a radionuclide-labeled compound that comprises a C2 domain of a protein or an active variant...

20060110324 - Human anti-epidermal growth factor receptor single-chain antibodies: Human anti-epidermal growth factor receptor (EGFR) single-chain antibodies (scFvs) were isolated from a human IgM phage display library using purified epidermal growth factor receptor as antigen. Two isolates with different amino acid sequences were identified by ELISA as epidermal growth factor receptor-specific. The scFvs bind to the full length epidermal...

20060110325 - Serotonin and catecholamine segment optimization technology: Methods of using amino acid precursors of the serotonin and catecholamine neurotransmitter systems and laboratory urinary assay of serotonin and catecholamine neurotransmitter levels for optimal treatment of neurotransmitter dysfunction and dysfunction of systems regulated or controlled by the serotonin and/or catecholamine neurotransmitter systems. The methods may also include determining a...

20060110326 - Toluidine blue o drug substance and use thereof for in vitro staining and chemotherapeutic treatment of dysplastic tissues: The invention comprises an improved process for preparing TBO drug products includes the steps: (1) synthesising an indamine; (2) converting said indamine into an S-indaminyl thiosulfate; and (3) adding an oxidizing catalyst agent, complexing agent, and an acid to said S-indaminyl thiosulfate to formulate TBO and C-4-methyl regioisomer, and derivatives...

20060110327 - Methods and compositions for deterring abuse of orally administered pharmaceutical products: This invention relates to an abuse deterrent formulation of an oral dosage form of a therapeutically effective amount of any active drug substance that can be subject to abuse combined with a gel forming polymer, a nasal mucosal irritating surfactant and a flushing agent. Such a dosage form is intended...

20060110331 - Compositions comprising azelastine and methods of use thereof: The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comprise one or more pharmaceutically acceptable carriers or excipients that reduce the amount of post-nasal drip, and/or that minimize...

20060110330 - Inhalable pharmaceutical compositions containing an anticholinergic, formoterol, and a steroid: e

20060110329 - Inhalable pharmaceutical compositions containing an anticholinergic, salmeterol, and a steroid:

20060110328 - Method of delivering nasal spray: A method of delivering a nasal spray. A sprayer having a formulation comprising olopatadine is provided. A spray of the formulation is delivered to a subject's nose. The spray may have a spray characteristic comprising a spray pattern having a longest axis of 20-45 mm, a shortest axis of 14-20...

20060110332 - Agent for medicamentous treatment of acute and chronic pain: The invention relates to an agent for the medicamentous treatment of acute and chronic pain, in particular of allodynia and hyperalgesia. Fields of application of the invention are medice and the pharmaceutical industry. A new pharmaceutical composition for the treatment of acute and/or chronic pain, in particular allodynia and hyperalgesiais...

20060110333 - Composition for nasal absorption: This invention attempts to provide a composition for intranasal administration which has markedly lower risk of developing side effects compared to oral formulation, which promptly exhibits analgesic effects, and which has excellent bioavailability. The composition for nasal absorption comprises a carrier of calcium carbonate and/or calcium phosphate having an average...

20060110335 - Aerosol hair styling composition: The present invention is related to a sprayable aerosol foam styling composition. The present invention aims at developing a foaming spray styling product with excellent volume up effect and with quick breaking foam, which makes partial application especially at hair root area possible. Furthermore the objective of the present invention...

20060110334 - Two-compartment aerosol device comprising electrophilic monomers, and use thereof for the cosmetic treatment of the hair: A two-compartment aerosol device comprising: (i) a first compartment comprising a cosmetic composition comprising, in at least one cosmetically acceptable medium, at least one electrophilic monomer, and (ii) a second compartment comprising at least one compressed gas, wherein the first and second compartments provide, during the use of the aerosol...

20060110336 - High-cleaning silica materials and dentifrice containing such: Unique abrasive and/or thickening materials that are in situ generated compositions of precipitated silicas and silica gels are provided. Such compositions exhibit different beneficial characteristics depending on the structure of the composite in situ generated material. With low structured composites (as measured via linseed oil absorption levels from 40 to...

20060110338 - High-cleaning/low abrasive silica and materials and dentifrice containing such materials: Unique abrasive and/or thickening materials that are in situ generated compositions of precipitated silicas and silica gels are provided. Such compositions exhibit different beneficial characteristics depending on the structure of the composite in situ generated material. With low structured composites (as measured via linseed oil absorption levels from 40 to...

20060110337 - High-cleaning/moderate abrasive silica materials and dentifrice containing such materials: Unique abrasive and/or thickening materials that are in situ generated compositions of precipitated silicas and silica gels are provided. Such compositions exhibit different beneficial characteristics depending on the structure of the composite in situ generated material. With low structured composites (as measured via linseed oil absorption levels from 40 to...

20060110339 - Viscosity-modifying silica materials that exhibit low cleaning and abrasive levels and dentifrices thereof: Unique abrasive and/or thickening materials that are in situ generated compositions of precipitated silicas and silica gels are provided. Such compositions exhibit different beneficial characteristics depending on the structure of the composite in situ generated material. With low structured composites (as measured via linseed oil absorption levels from 40 to...

20060110340 - Compositions and methods for whitening, mineralizing and/or fluoridating calcified tissues: Kits and methods that combine whitening/stain removal of teeth with remineralization are disclosed. These kits advantageously comprise separate compositions comprising a soluble calcium salt, a soluble orthophosphate salt, and a soluble peroxide, in order to optimize the stability of these components for storage and/or the activity of these components upon...

20060110341 - Cosmetic compositions containing sophora alopecuroides l. extracts: Disclosed are extracts of Sophora alopecuroides L. as cosmetic skin lightening agents alone or in combination with other skin benefit agents and together with a cosmetic vehicle. Also disclosed are active ingredients in the extracts, including Alopecurone A, Alopecurone B, Sophoraflavone-G, Sophoraflavone-I, Sophoraflavone-K, and mixtures thereof. The inventive extracts, compositions...

20060110342 - Organo-gel formulations for therapeutic applications: A composition suitable for the local delivery of cosmetic and/or pharmaceutical agents into the skin containing at least two biocompatible organic solvents, a polar lipid, a surfactant, water, urea and a thickener wherein the organic solvents include an ester and a dihydric and/or polyhydric alcohol is provided. Also disclosed are...

20060110343 - Cosmetic or dermopharmaceutical compositions comprising tyramine derivatives, method for preparing same, and use thereof: The invention concerns cosmetic or dermopharmaceutical compositions comprising tyramine derivatives and their salts. The invention also concerns the method for preparing same and use thereof for reducing pigmaentation....

20060110344 - Water-swellable clay mineral laminated powder, dye/water-swellable clay mineral complex and composition comprising the same: The water-swellable clay mineral laminated powder of the present invention is characterized in that a layer of ionic molecule having two or more ionic functional group is laminated on the surface of a base powder particle, and a layer of water-swellable clay mineral is laminated thereon, and the layers are...

20060110345 - Cosmetic composition containing a polyorganosiloxane polymer: The invention relates to a physiologically acceptable composition, especially a cosmetic composition, containing: at least one structuring agent selected from the group consisting of a polyorganosiloxane-containing polymer, a non-silicone-polyamide copolymer, a wax, and mixtures thereof; (b) a hydrocarbyl-functional silicone polymer; (c) optionally, at least one silicone film former; (d) optionally,...

20060110346 - Transfer-resistant cosmetic compositions: Transfer-resistant cosmetic compositions containing at least one silicone resin and at least one silicone pressure sensitive adhesive and methods of use thereof....

20060110347 - Cosmetic compositions and methods of use: The present invention relates to a cosmetic composition containing a phenyl substituted organosiloxane to provide shine and/or gloss when applied to a keratinous material, such as skin....

20060110348 - Therapeutic composition containing an organosilane quaternary compound and hydrogen peroxide for treating skin disorders and methods of using: Therapeutic skin cleansing and multifunctional coating compositions containing hydrogen peroxide and an organosilane quaternary compound in aqueous formulations are used to treat skin disorders including wounds, abrasions, ulcers, burns, infections, irritations, microbes, soil, water, psoriasis, acne vulgaris, blemishes, age spots, sclerosis, other physical or chemical injuries, and other skin deficiencies....

20060110350 - Composition comprising electrophilic monomers and particular organic salts, and use thereof for cosmetic treatment of keratin materials: The present invention relates to a composition comprising in a cosmetically acceptable medium at least one electrophilic monomer and at least one non-polymeric organic salt having a melting point of less than 60° C., and to its use for the cosmetic treatment of keratin materials. It also relates to a...

20060110349 - Hair care composition: A hair treatment composition comprising (i) 2-hydroxyalkanoic acid and; (ii) 0.1 to 10 wt % of a styling aid....

20060110351 - Use of silanes on cosmetic agents and methods for treating hair: The cosmetic agent contains from 0.01 to 10 percent by weight of at least one silane of formula RmSiX4-m, wherein m=0 to 4, R is a nonhydrolyzable organic group and X is a hydrolysable group, or a salt thereof. The method for improving the condition of hair, particularly in terms...

20060110352 - Cosmetic, pharmaceutical and dermatological compositions: X+ is Li+, Na+, K+, Mg2+/2, Ca2+/2, Al3+/3, NH4+, monoalkylammonium, dialkylammonium, trialkylammonium or tetraalkylammonium, the alkyl substituents of the ammonium ions being independently of one another (C1-C22) alkyl radicals or (C2-C10) hydroxyalkyl radicals, or singly to triply ethoxylated ammonium compounds having the same or different degree of ethoxylation, it being...

20060110353 - Aerosol device comprising at least one high molecular weight polyurethane: Disclosed herein is a composition for cosmetic treatment of keratin materials, packaged in an aerosol device comprising (a) at least one propellant and (b) a hairstyling composition comprising at least one polyurethane having a number-average molecular weight ranging from 400 000 to 5 000 000 g/mol, in a cosmetically acceptable...

20060110354 - Concentrated surface-active preparations: Concentrated surface-active preparations with low viscosity are disclosed, comprising (a) 25 to 55 wt. % amphoteric or zwitter-ionic surfactants (b) 0.01 to 5 wt. % alkaline sulfates, with the proviso that the amounts are made up to 100 wt % with water and, optionally, further electrolytic salts....

20060110355 - Anhydrous cosmetic composition capable of forming an organogel: The present invention relates to an anhydrous cosmetic composition containing, in a physiologically acceptable medium, at least one fatty phase comprising at least one short hydrocarbon-based ester and at least one non-hydrogenated glycerophospholipid, the said short hydrocarbon-based ester and the said non-hydrogenated glycerophospholipid being present therein, respectively, in contents corresponding...

20060110356 - Ophthalmic drug delivery system using polymer micelle: The current situation is such that it is difficult for drugs to reach posterior tissues of an eyeball, such as choroid and retina, with the result that treating diseases in such regions is difficult. Thus, how to attain effective delivery of drugs is of importance. It has been found that...

20060110357 - Bone putty composition that maintains granule suspension at reduced temperatures: The invention is directed to a bone putty composition comprising a carrier formulation comprising water and a carrier substance, and granules wherein said bone putty composition exhibits gel-like Theological properties throughout the temperature range between about body temperature and temperatures approaching about 0° C. The bone putty composition further exhibits...

20060110358 - Combination therapy for treatment of fibrotic disorders: The present invention provides methods of treating a fibrotic disorder. The methods generally involve administering an effective amount of IFN-γ and an effective amount of pirfenidone or a pirfenidone analog....

20060110359 - Cellular delivery of natriuretic peptides: The present invention pertains to a method for treating deficits, such as neurological deficits, caused by focal or generalized edema associated with injury to the central nervous system, heart, liver, and kidney. The present invention further concerns a method for producing natriuretic peptides and pharmaceutical compositions comprising bone marrow stromal...

20060110360 - Methods of treating tumors using natural killer cell lines: This invention relates to a natural killer cell line termed NK-92. The invention provides a vector for transfecting a mammalian cell which includes a nucleic acid sequence encoding a cytokine that promotes the growth of NK-92. Additionally, the invention provides an NK-92 cell, or an NK-92 cell modified by transfection...

20060110361 - Methods of making viral particles having a modified cell binding activity and uses thereof: The present invention relates to a method for packaging viral particles such that one or more peptides on the surface of the article are derived from the packaging cell. By incorporating certain peptides it is possible to target viral particles to specific cell types. Such a system is of use,...

20060110363 - Mutant having uracil phosphoribosyl transferase activity: The invention concerns a polypeptide having a uracil phosphoribosyl transferase (UPRTase) by mutation of one or several residues of the UPRTase. The invention also concerns a nucleotide sequence coding for the UPRTase mutant, a vector for expressing the latter, a viral particle, a host cell, and a composition containing them....

20060110362 - Sequences upstream of the carp gene, vectors containing them and uses thereof: The invention relates to novel promoter sequences derived from a portion upstream of the coding sequence of the gene for the CARP protein (Cardiac Ankyrin Repeat Protein), and which are capable of controlling the level and the specificity of expression of a transgene in vivo in cardiac muscle cells. The...

20060110364 - Vector-mediated delivery of polynucleotides encoding soluble vegf receptors: The present invention provides vector compositions for expression of a soluble form of VEGFR3 and methods for their use in the inhibition of one or more of lymphangiogenesis, lymphatic metastasis and angiogenesis, as a therapeutic strategy for treatment of cancer....

20060110377 - Immunologically privileged cells and uses thereof: The invention is directed to immunologically privileged cells, e.g., autologous, allogeneic, and xenogeneic intermediate lobe pituitary cells, for delivering polypeptides, e.g., insulin, to a subject, and to methods of using the same....

20060110376 - Mda-7 and free radicals in the treatment of cancer: The present invention relates to methods of treating a cancer in a subject comprising generating within one or more cancer cells of a subject an effective amount of MDA-7 and an effective amount of one or more free radicals. The present invention further relates to methods of inhibiting proliferation or...

20060110375 - Method for producing cell lines and organs by means of differentiable cells: A method for producing cell lines or individual organs, differentiable donor cells being supplied to a morula or blastocyst which is cultivated under conditions that ensure a further development of the morula or blastocyst in stages in which newly formed cell lines having a higher degree of differentiation occur, as...

20060110367 - Compositions and methods for inhibiting pathogenic growth: The invention includes methods and compositions for treating an animal to inhibit the incidence and growth of E. coli O157:H7 and other pathogenic bacteria. The treatment method comprises administering a therapeutically effective amount of Lactobacillus acidophilus or one or a combination of a number of other probiotic bacteria to an...

20060110366 - Entomopathogenic microorganism spores carrier and method for controlling harmful insects: The patent describes a method of selective application of entomopathogenic fungi, characterized by employing an attractant-contaminant device in which the spores of said fungus are fixed on an adsorbent material; this same adsorbent material or another, depending on the case, incorporates a specific attractant and is located on an adherent...

20060110365 - Novel bacterium for treatment of disease: This invention relates to compositions comprising a bacterium of the genus Dietzia that is useful for treating paratuberulosis in ruminants and to a method for culturing the bacterium. The invention further relates to methods of treating Johne's disease by administering to a mammal a composition of the invention....

20060110369 - Cell-filled device of modifield cross-section hollow fiber membrane type: To provide a cell-filled device that is suitable for use in, for example, an implantable or circulation type hybrid artificial organ. In a cell-filled device including hollow fiber membranes whose hollow portions are filled with cells, the hollow fiber membranes have modified cross sections, and a cell aggregate provided in...

20060110371 - Control of indoleamine 2,3 deoxygenase expression and activity: The present invention relates to controlling and/or manipulating of dendritic cells by controlling the expression and activity of indoleamine 2,3 deoxygenase expression and activity....

20060110368 - Medium for culturing autologous human progenitor stem cells and applications thereof: Described is a medium for the autologous culture of autologous human progenitor stem cells, which comprises: between 0.1 and 90 wt.-% autologous human serum; between 0.1 and 10,000 UI/ml heparin; between 0.1 and 10,000 UI/ml protamine; and a culture medium consisting of basic nutrients with or without glutamine, in a...

20060110374 - Method to accelerate stem cell recruitment and homing: A method is provided for facilitating treatment of a patient, including stressing a portion of the patient to an extent sufficient to induce homing of progenitor cells to the portion of the patient. A method is additionally provided for use with tissue of a patient, including evaluating an indication of...

20060110373 - Ptu compounds for promoting the in vitro culture of (highly pigmented) melanocytes: A method for promoting the in vitro multiplication of human melanocytes and/or the freezing thereof, notably human melanocytes obtained from individuals of phototype IV, V or VI or from hyperpigmentary lesions, entails introducing into a culture of same, a thus effective amount of at least one 1-phenyl-3-(2-thiazolyl)-2-thiourea (PTU) compound or...

20060110372 - Regulatory cells that control t cell immunoreactivity: [Solution means] CD8+CD122+ T cell subsets are provided as regulatory T cells that suppress activity of activated CD8+ killer T cells. Administration of these T cell subsets can suppress tissue/cell damages. In addition, it has become possible to explore agents that augment immunosuppressive activity of these T cell subsets by...

20060110370 - Treatments for reduction of cytotoxicity and viral contamination of implantable medical devices: A method for treating biomaterial is provided in which a biological tissue, typically after being cross-linked, is contacted with an anticalcification treatment solution under condition effective to render the biomaterial resistant to in vivo calcification upon implantation in a host animal. The anticalcification treatment solutions comprise higher alcohol solutions, a...

20060110378 - Agent for prevention and treatment of inflammatory bowel disease: The present invention provides a therapeutic agent for treating inflammatory bowel diseases comprising as an active ingredient at least one member selected from polypeptides belonging a family exhibiting thioredoxin activity....

20060110379 - Linkage of agents using microparticles: Methods, products and kits are provided for attaching agents to a skin surface via microparticles using endogenous or exogenous transglutaminase....

20060110380 - Compositions for inhibiting thrombin-induced coagulation and methods of use: A method of achieving safe and effective treatment or prevention of potentially harmful blood clots, or in inhibiting the coagulation of blood when so desired such as during a wide array of disease conditions including stroke, myocardial infarction, sickle-cell crisis and venous thrombosis, is provided by the administration of a...

20060110381 - Hemostatic compositions containing sterile thrombin: The present invention includes sterilized hemostatic compositions that contain a continuous, biocompatible liquid phase having a solid phase of particles of a biocompatible polymer suitable for use in hemostasis and that is substantially insoluble in the liquid phase, and sterile thrombin, each of which is substantially homogenously dispersed throughout the...

20060110382 - Antibody peg positional isomers, compositions comprising same, and use thereof: The present invention relates to recombinant protein PEG positional isomers. More specifically, it relates to PEG positional isomers of an antibody having specificity for antigenic determinants of human tumor necrosis factor alpha (TNFα). More specifically, it relates to PEG positional isomers of CDP870. The present invention also relates to compositions...

20060110383 - Immunopotentiative composition: Compositions for cancer or infection treatment via immunopotentiation caused by inhibition of immunosuppressive signal induced by PD-1, PD-L1, or PD-L2 and therapies using them, immunopotentiative substrates included as the active ingredient, screening methods of the substrates for cancer or infection treatment, cell lines used for the screening methods, evaluation methods...

20060110386 - Mammalian cytokines; receptors; related reagents and methods: Nucleic acids encoding mammalian cytokine receptor, e.g., for cytokine IL-B50, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described....

20060110385 - Means and methods for diagnosing and treating affective disorders: The present invention relates to nucleic acid molecules, preferably genomic sequences, encoding an ATP-gated ion channel P2X7R which contain a mutation in the 5′UTR or 3′UTR regions, a mutation in exon 3, 5, 6, 8 or 13 or in introns 1, 3, 4, 5, 6, 7, 9, 11 or 12...

20060110384 - Novel proteins and use thereof: The present invention provides a novel secretory/membrane protein associated with adipocyte differentiation and/or metabolism function, specifically, an adipocyte-derived secretory/membrane protein containing amino acid sequence which is the same or substantially the same as an amino acid sequence represented by SEQ ID NOS: 2, 4, 6, 8, 10, 12, 14, 16,...

20060110387 - Method for treating vasculitis: A method of treating anti-neutrophil cytoplasmic antibodies-associated vasculitis (ANCA-associated vasculitis) in a patient eligible for treatment is provided involving administering an antagonist that binds to a B-cell surface marker, such as CD20 antibody, to the patient in a dose of about 400 mg to 1.3 grams at a frequency of...

20060110388 - ß binding molecules: The present invention encompasses isolated antibodies, or fragments thereof, that are humanized variants of murine antibody 266 which employ complementarity determining regions derived from murine antibody 266. The variant antibodies are useful for treatment or prevention of conditions and diseases associated with Aβ, including Alzheimer's disease, Down's syndrome, cerebral amyloid...

20060110389 - Method of treatment using anti-il-18 antibody: Disclosed are artificially produced peptide capable of neutralizing the biological activities of IL-18, which comprises a part or the whole of the variable regions in anti interleukin 18 antibody, including single chain variable region fragments and humanized antibodies, a process of producing the peptide, and uses thereof. The peptide is...

20060110391 - Compositions and methods for the treatment of body weight disorders, including obesity: The invention provides isolated nucleic acids molecules, designated MKP nucleic acid molecules, which encode novel MAP kinase phosphatase family members, and their use in metabolic disorders. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MKP nucleic acid molecules, host cells into which the expression vectors have...

20060110390 - Inhibition of ku as a treatment for cardiovascular diseases: The present invention provides for methods of treating and preventing cardiovascular diseases, in particular pathological cardiac hypertrophy and chronic heart failure, by applying an inhibitor of Ku. The present invention also provides for methods of screening to find inhibitors of Ku and inhibitors of cardiac hypertrophy and heart failure....

20060110392 - Murine monoclonal antibody (5c8) recognizes t-b cell activating molecule (t-bam) (cd40 ligand) on the surface of t-lymphocytes, compositions containing same and methods of use: The present invention provides a monoclonal antibody capable of binding to a protein which is specifically recognized by monoclonal antibody 5c8 produced by the hybridoma having ATCC Accession No. HB 10916. This invention also provides compositions comprising the antibody, and hybridomas that produce the antibody. This invention also provides an...

20060110397 - Aimp2-dx2 and its uses: The present invention relates to a variant of AIMP2 lacking exon 2, named as AIMP2-DX2, which is specifically expressed in cancer cells. The AIMP2-DX2 protein and gene can be successfully used in the development of diagnosis and treatment of cancer....

20060110398 - Dap-10 and uses thereof: The present invention relates to methods for identifying and using modulators of DAP10 biological activity in vitro and in vivo that are useful in the treatment of cancer and autoimmunity....

20060110394 - Humanized anti-vla 4 immunoglobulins and uses thereof: The invention provides methods of treatment using humanized immunoglobulins that specifically bind to alpha-4 integrin. The methods are useful for treatment of asthma, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, transplant rejection, graft versus host disease, tumor metastasis, nephritis, atopic dermatitis, psoriasis, myocardial ischemia, and acute leukocyte mediated...

20060110393 - Novel proteins and use thereof: Compounds that inhibit the expression of a protein comprising the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1, SEQ ID NO: 4, SEQ ID NO: 7 or SEQ ID NO: 10 or the expression of a gene for the...

20060110395 - Use of crkd as a breast cancer marker and cancer therapy target: In certain aspects, the present invention discloses the use of CRKD as a marker for a cell-proliferative disorder, preferably as a marker for breast cancer. The invention discloses antibodies and fragments thereof which specifically bind CRKD, methods of diagnosing, methods for assessing CRKD status, methods of monitoring the efficacy of...

20060110396 - Use of ligands of the antigen cdw52 for the treatment of diseases that are related to degenerated macrophages: The present invention relates to the use of a ligand of CDw52 for the preparation of a medicament for the treatment of diseases that are related to CDw52 expressing degenerated macrophages. In particular, the present invention relates to the treatment of diseases such as MAS, LCH, HLH, and AML....

20060110399 - Optimal placement of a robust solvent/detergent process post viral ultrafiltration of an immune gamma globulin: The solvent-detergent (S/D) process is used to inactivate enveloped viruses in plasma products. While concentrations of 1.0% detergent and 0.3% tri-n-butyl phosphate solvent have been considered necessary for robust removal of viral activity, we show the effectiveness of solvent-detergent treatment after fractionation and nanofiltration of an immune gamma globulin preparation,...

20060110400 - Immunogenic conjugates: The invention relates to an immunogenic conjugate comprising at least one vascular endothelial growth factor (VEGF) peptide moiety coupled to a carrier....

20060110401 - Mixture of peptides from c and ns3 proteins of the hepatitis c virus and applications thereof: The invention relates to a peptide mixture including at least two different peptides from the hepatitis C virus (HCV), whereby at least one of them is a peptide from the C protein binding to at least four different HLA-II molecules, the occurrence of which exceeds 5% in the Caucasian population...

20060110402 - Decolorized yeast cell wall fraction: The yeast cell wall fraction comprising cell residues obtained by removing internal soluble components from enzyme-treated yeast, or cell residues obtained by treating the cell residues with acid solution and removing the acid solution-soluble components. By decolorizing the residues with a decolorizing agent, the decolorized yeast cell wall fractions to...

20060110403 - Non-human herpesviruses as vectors: The present invention relates to animal viruses such as animal herpesviruses as a vector for diagnostic, therapeutic and prophylactic delivery of foreign genes and nucleic acids to animals, human or primary cells derived thereof, respectively. By using said viruses, the prevention and treatment of infectious, autoimmune and tumor diseases as...

20060110405 - Plasma or serum fraction for treatment and prevention of viral infections and related conditions: The present invention describes compositions and methods for the treatment and/or prevention of viral infections and related conditions, including HIV infections....

20060110404 - Set of ubiquitous cellular proteins involved in viral life cycle: A method of modulating viral RNA replication and translation, in a eukaryotic cell, of positive-strand viral RNA, comprising the step of contacting a viral RNA-binding protein (vRbp) with a compound that modulates an activity of said protein....

20060110406 - Refrigerator-temperature stable influenza vaccine compositions: Methods and compositions for the optimization and production of refrigerator-temperature stable virus, e.g., influenza, compositions are provided. Formulations and immunogenic compositions comprising refrigerator-temperature stable virus compositions are provided....

20060110407 - Immune globulin formulations for the treatment and prevention of an orthopoxvirus infection: The invention provides an immune globulin having a high titre of antibody to Orthopoxvirus, pharmaceutical compositions comprising the immune globulin and methods for making same. In one embodiment the immune globulin is intravenously injectable. The invention also provides a colorimetric assay to detect neutralizing antibodies to vaccinia virus. The invention...

20060110408 - Immunological combination compositions and methods: Immununological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the lipoprotein a recombinantly expressed product having an OspA leader...

20060110410 - Recombinant toxin fragments: A single polypeptide is provided which comprises first and second domains. The first domain enables the polypeptide to cleave one or more vesicle or plasma-membrane associated proteins essential to exocytosis, and the second domain enables the polypeptide to be translocated into a target cell or increases the solubility of the...

20060110409 - Targeted agents for nerve regeneration: A conjugate, for delivery of a therapeutic agent to a neuronal cell, comprises the therapeutic agent, a binding domain that binds to the neuronal cell, and a translocation domain that translocates the therapeutic agent into the neuronal cell, wherein the binding domain is HC of botulinum C1 toxin or is...

20060110411 - Streptococcus equi vaccine compositions and method of use: This invention relates to compositions comprising live, attenuated Streptococcus equi (S. equi), or a fractional extract of S. equi, in combination with at least one immunostimulant for stimulating mucosal immunity, such as saponin. The invention also relates to methods of preparation and dosage forms containing the composition of the invention...

20060110412 - Vaccine composition: The present invention relates to vaccine compositions for the effective prevention of neisserial, preferably meningococcal, disease. The vaccine of the invention comprise a multivalent meningococcal bled composition comprising at least one bleb with homologous bactericidal activity which is derived from a meningococcal strain with a serosubtype that is prevalent in...

20060110417 - Beauty products and methods: A beauty kit including a beauty product having a beauty product identifier, and at least one template having a facial feature including one or more facial feature identifiers arranged in a predetermined pattern. The facial feature identifiers correspond to the beauty product identifier....

20060110416 - Hydroalcoholic cosmetic compositions: A hydroalcoholic cosmetic composition is provided which when topically applied to the face can shrink skin pores. The composition is focused upon denatured ethyl alcohol utilizing menthol as denaturing agent. Further included in the composition are humectants, preservatives and water. Also described is a method for reducing skin pore size....

20060110413 - Novel molecules dervied from noraporphine: The invention concerns novel molecules derived from noraporphine, as well as cosmetic and dermopharmaceutical compositions containing one or several of said derivatives, alone or combined with a plant extract, in particular glaucium flavum, and particularly preparations for reducing pigmentation, with anti-ageing effect or for slimming....

20060110414 - Oily skin preparation for external use: The objective of this invention is to provide an oily external composition for skin having an excellent rough skin recovering/preventing effect, and wherein powder is well dispersed in oil. An oily external composition for skin of this invention is characterized in that comprising a complex powder (the surface of lipophilic...

20060110415 - Topical delivery system for cosmetic and pharmaceutical agents: This invention relates to topical compositions containing esters of hydroxy acids and their application in the deep-penetration delivery of beneficial cosmetic and pharmaceutical agents....

20060110418 - Water-in-oil emulsions and methods: The present invention provides a process for delivery of water nanoclusters of diameter less than about one nanometer to the skin to yield high epidermal permeability and improved delivery of water to within the outer layer of human skin. This invention provides effective water-cluster-based formulations for a broad range of...

20060110421 - Garbage bag or container: An article, such as a container or bag for garbage, which repels animals such as cats, dogs, rats, and crows. The article may be made from a synthetic resin composition including a synthetic resin and from 10 to 15,000 ppm by weight of a salicylic acid ester, menthol and/or camphor....

20060110420 - Synthetic pheromone compositions: The present invention provides compounds useful for preparing synthetic pheromone compositions that can be used as attractants or inhibitors of insect species. The compositions are useful in the control of navel orangeworm or meal moth insect pests....

20060110419 - Water resistant sunscreen and insect repellant towel: A single-use disposable applicator for applying sunscreen and insect repellent to the skin is a non-woven, woven or porous fibrous material wipe that is saturated with a composition containing a waterproof sunscreen agent and an insect repellent. A film forming agent and solvent may also be present. When rubbed over...

20060110424 - Ceramic and metal compositions: A novel metal/ceramic hybrid material in which the void space of the ceramic is filled with metal. The metal may be bonded to the ceramic, for example by formation of a metal oxide. The metal may be introduced into the ceramic as small particles in a suspension then heated to...

20060110422 - Conversion of calcite powders into macro- and microporous calcium phosphate scaffolds for medical applications: Disclosed is a method for forming carbonated calcium hydroxyapatite. The disclosed method can be used for forming bone cements or optionally cast, cured scaffolds such as may be used in many medical applications, including as implants for bone damage caused by, for instance, trauma, disease, or surgical excision due to...

20060110423 - Polymer-based sustained release device: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar....

20060110426 - Cohesive coprecipitates of sulfated polysaccharide and fibrillar protein and use thereof: The present invention concerns cohesive biopolymer gels comprising coprecipitates of sulfated polysaccharides and fibrillar proteins, exemplified by coprecipitates of dextran sulfate and gelatin, useful for clinical applications including as implants for tissue engineering as well as in biotechnology. The cohesive biopolymer gels according to the present invention may be used...

20060110425 - Leech extracts for stents: The invention relates to a stable destabilase complex in the form of a monomer, which is capable of aggregating into a polymer destabilase complex forming a liposome and which can be obtained from medicinal leeches using the following method comprising: affinity chromatography with 6-keto-prostaglandin antibodies which are immobilised on a...

20060110429 - Implant for intraocular drug delivery: An implant for intraocular drug delivery for the treatment of inflammatory or degenerative diseases. In one embodiment, the implant includes a body portion having a first end portion and a second, opposite end portion and defining a cavity with a first opening at the first end portion, and a second,...

20060110428 - Methods and devices for the treatment of ocular conditions: Featured is a method for instilling one or more bioactive agents into ocular tissue within an eye of a patient for the treatment of an ocular condition, the method comprising concurrently using at least two of the following bioactive agent delivery methods (A)-(C): (A) implanting a sustained release delivery device...

20060110427 - Ophthalmic compositions comprising polyether substituted polymers: The present invention relates to ophthalmic solutions and devices comprising at least one water soluble polymer having a molecular weight of at least about 500,000 Daltons and comprising linear or branched polyether pendant groups having a molecular weight of at least about 300....

20060110430 - Copolymerizable azo compounds and articles containing them: Polymerizable light absorbing azo dyes are disclosed useful as monomers in the formation of devices such as, but not limited to ocular lenses. Specifically, intraocular lenses (IOL) are disclosed wherein one or more of the light absorbing dye is covalently bonded to other structural polymers though ethylene unsaturated groups. The...

20060110432 - Lotion-treated tissue and towel: A paper towel includes: (a) a cellulosic towel web; and (b) a lotion emulsion disposed on the towel web. The lotion emulsion is substantially liquid at room temperature and includes a polar emollient and a non-polar emollient as well as a surfactant composition comprising a nonionic surfactant; wherein the emollients...

20060110431 - Sheets having alternating areas of relatively high and low lotion add-on in the machine direction: Lotion-containing sheets, such as tissue sheets or non-woven sheets, having alternating areas of high and low lotion add-on in the machine direction of the sheet have been found to reduce or eliminate downstream build-up of lotion on process equipment....

20060110433 - Adhesive patch: A patch comprising a backing layer and an adhesive layer disposed on the backing layer and compounded with an adhesive base agent and pergolide and/or a pharmaceutically acceptable salt thereof, wherein the adhesive base agent comprises an acrylic polymer including no substantial carboxyl group and hydroxyl group and having self-adhesion...

20060110434 - Drug-containing patch: The problem of the invention is to provide a drug-containing patch which is very favorable in percutaneous absorbability and is excellent in sustainability of the drug efficacy, that is, the drug-containing patch having a sufficient percutaneous absorbability and effect sustainability in a degree to be actually used for therapy of...

20060110435 - Allergy vaccine composition, production method thereof and use of same in allergy treatment: The present invention relates to the field of Immunology, specifically with the branch of Immuno-Allergy and in particular with the use of adjuvant or carrier compounds, capable of modulating the immune response to allergens. The technical objective that is pursued is to obtain a pharmaceutical preparation of therapeutic or prophylactic...

20060110439 - Dermal delivery of n-methyl-glucamine and n-methyl-glucamine compounds: The present invention relates to methods and compositions for the treatment of skin-related conditions and disorders. In one aspect, the invention features methods and compositions for the transdermal delivery of compounds for the treatment of skin-related conditions and disorders, wherein the compositions include meglumine and a liposome component....

20060110438 - Liposome stabilizing agent: [wherein M represents a hydrogen atom or a monovalent cation and m, which defines the methylene chain length, represents an integer of 1 to 5], and the other two each represent an chain hydrocarbon group, A1, A2 and A3 are each independently selected from the group consisting of C(O)O, CONH...

20060110441 - Lyophilized liposome formulations and method: Formulations and methods for preparing a lyophilized composition comprising liposomes comprised of an unsaturated lipid and a hydrophobic drug associated with the liposome, and a cryoprotectant in a solution at a selected concentration. The phase transition temperature of the lipid is greater than the freezing point of the solution at...

20060110440 - Method and system for biasing cellular development: Compositions and methods comprising siRNA targeted to APP mRNA are advantageously used to transfect stem cells and bias the cells against differentiating into glial type neural cells. The siRNA of the invention causes RNAi-mediated silencing of the APP mRNA. The inventors have discovered that expression APP induces gliogenesis, i.e., promotes...

20060110436 - Phospholipid derivative: A phospholipid derivative, utilizable for modification of liposomes and the like, which is a copolymer containing, as essential component units, a component unit A represented by the formula (1), a component unit B represented by the formula (2A) and/or the formula (2B), and a component unit C represented by the...

20060110437 - Synthesis and self-assembly of abc triblock bola peptide: The present invention provides for bola amphiphiles compositions which have more than one lyophilic (hydrophilic) head group and a hydrophobic (hydrophobic) moiety capable of hydrogen bonding with other bola amphiphiles. These bola amphiphiles are capable of self assembling into micelles. The advantage of these bola amphiphiles is that they may...

20060110442 - Coated sherical seamless filled capsules: Described is a spherical coated capsule comprising (a) a coating-free capsule having (i) a liquid or viscous core and (ii) a seamless solid shell surrounding this core, and (b) a seamless, solid coating surrounding said coating-free capsule, wherein—the diameter of the coated capsule is in the range of 5-9 mm,...

20060110443 - Method and form of a drug delivery device, such as encapsulating a toxic core within a non-toxic region in an oral dosage form: A drug delivery device such as an oral dosage form (ODF) with a toxic or potent core encapsulated by a non-toxic region. The non-toxic region may be a region including multiple layers, coatings, shells, and combinations thereof, which provides protection to and isolation from the toxic or potent core. The...

20060110450 - Bilayer tablet of telmisartan and amlodipine: A bilayer tablet comprises a first layer formulated for instant release of the angiotensin II receptor antagonist telmisartan from a dissolving tablet matrix and a second layer formulated for instant release of the calcium channel blocker amlodipine from a disintegrating or eroding tablet matrix....

20060110453 - Calcium hypochlorite blended tablets: A non-Division 5.1 Oxidizer tablet consisting essentially of a blend of hydrated calcium hypochlorite with magnesium sulfate heptahydrate, wherein the blend contains at least about 17% by weight of water based on the total weight of the blend; contains from about 0.1% to about 10% of lime based on the...

20060110448 - Combination of a macrolide and a local anesthetic for the treatment of dermatological diseases: Synergistic combinations of a macrolide T-cell immunomodulator or immunosuppressant such as 33-epichloro-33-desoxyascomycin and a local anaesthetic such as lidocaine, polidocanol or prilocaine are provided, which are useful in particular in the treatment of dermatological diseases such as atopic, contact or seborrhoeic dermatitis, psoriasis, acne, rosacea, post-peel, pruritus, skin burning, or...

20060110447 - Controlled and continued delivery of rifaximin and/or other substances: A gum-like device is designed for the controlled and continued delivery of rifaximin, without producing the usually intense red coloration, for the resolution of the infections and the reduction of the inflammation in the oral cavity and in the laryngo-pharyngeal one. The device also protects either the gum or the...

20060110446 - Deferacirox dispersible tablets: The invention pertains to dispersible tablets comprising as active ingredient 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid or pharmaceutically acceptable salt thereof in an amount of from 5 to 40% in weight by weight of the total tablet....

20060110445 - Dispersible tablet for oral administration: The present invention relates to a process for the preparation of a dispersible tablet dosage form comprising β-lactam antibiotics for oral administration....

20060110452 - Dosage forms of risedronate: Oral dosage forms of a risedronate comprised of a safe and effective amount of a pharmaceutical composition comprising risedronate, a chelating agent, and, means for effecting delayed release of the risedronate and the chelating agent in the small intestine provide immediate release of the pharmaceutical composition to the small intestine...

20060110451 - Formulations of [1,4]diazepino[6,7,1-ij]quinoline derivatives: The present invention provides solid dosage formulations of [1,4]diazepino[6,7,1-ij]quinoline derivatives and processes for their manufacture. In some particular embodiments, the present invention provides novel formulations of the antipsychotic and antiobesity agent (9aR,12aS)-4,5,6,7,9,9a,10,11,12,12a-decahydrocyclopenta[c][1,4]diazepino[6,7,1-ij]quinoline hydrochloride (Compound A.HCl)....

20060110449 - Pharmaceutical composition: The present invention relates to formulations useful for treating respiratory disorders associated with the production of mucus glycoprotein, skin disorders, and allergic conjunctivitis while substantially reducing adverse effects associated with the administration of non-selective anti-cholinergic agents and methods of use thereof....

20060110444 - Solid dosage form comprising a fibrate: The invention provides stable, solid dosage forms and pharmaceutical compositions in particulate form comprising a fibrate, for example fenofibrate, dissolved in an non-aqueous vehicle in order to ensure improved bioavailability of the active ingredient upon oral administration relative to known fibrate formulations....

20060110455 - Antiviral product, use and formulation thereof: An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosage form, as well as two or more...

20060110454 - Extended release formulation of pramipexole dihydrochloride: An extended release composition of Pramipexole or a pharmaceutical acceptable salt thereof, wherein the active agent is coated on a non pareil inert core, the drug loaded core is further coated with a polymeric layer which enables the release of the active agent over an extended period and optionally the...

20060110456 - Method for biocidal and/or biostatic treatment and compositions therefor: There is provided a method of biocidal and/or biostatic treatment and compounds and compositions thereof. In particular, there is provided a composition comprising at least one compound having the formula R1R2NR3, wherein R1, R2 and R3, are selected from the group consisting of hydrido, alkyl, aryl, heteroaryl, cycloalkyl, cycloaryl, cycloheteroaryl,...

20060110457 - Heat cured gel and method of making: A method of curing and corresponding resulting non-polymeric cross-linked gel are provided. The cross-linked gel can be combined with a medical device structure. The cross-linked gel can provide anti-adhesion characteristics, in addition to improved healing and anti-inflammatory response. The cross-linked gel is generally formed of a naturally occurring oil, or...

20060110458 - Sustained release drug carrier: The present invention aims to provide completely biodegradable and biocompatible sustained-release carriers for proteins or peptides, which allow encapsulation of the proteins or peptides at high encapsulation rates without inhibiting their biological activity. The present invention provides a method for preparing a sustained-release carrier, wherein in a solution in the...

20060110459 - Triple natural polymer viscoelastic composition: A triple natural polymer viscoelastic composition is disclosed. By combining glucosamine sulfate (“GS”), sodium hyaluronate (“HA”) and chondroitin sulfate (“CS”), the triple natural polymer viscoelastic compositions of this invention can provide a viscoelastic agent at a surgical site that not only serves as a protective agent to ocular tissues, but...

20060110462 - Nanoparticulate compositions of tubulin inhibitor compounds: The present invention is directed to novel pharmaceutical compositions comprising nano- and micro-particulate formulations of poorly water soluble tubulin inhibitors of the indole chemical class, preferably N-substituted indol-3-glyoxyamides, and more preferably N-(Pyridin-4-yl)-[1-(4-chlorobenzyl)-indol-3-yl]glyoxylic acid amide (D-24851), also known as “Indibulin,” and methods of making and using such compositions for the treatment...

20060110461 - Non-food and non-pharmaceutical use of a selected anhydrous dextrose composition: The present invention relates to the non-food and non-pharmaceutical use of a powder anhydrous dextrose composition, characterized by the fact that the composition has: a) a particle size such that: at most 4% of its particles (expressed as a volume) have a size at most equal to 40 microns, and...

20060110460 - Prolonged release biodegradable microspheres and method for preparing same: The invention concerns a method for preparing a pharmaceutical composition in the form of microspheres with prolonged release of a water-soluble active principle. The invention is characterized in that it comprises the following successive steps: dissolving an active principle in an appropriate amount of water; emulsifying the resulting aqueous solution...

20060110464 - Material encapsulation system: A material encapsulation and release system having a first zone (1) containing a first amount of material (2) bound by a first capsule wall (3) and, if desired, a second zone (4) containing a second amount of material (5) bound by a second capsule wall (6), each capsule wall responsive...

20060110463 - Oral pharmaceutical formulation in the form of aqueous suspension of microcapsules for modified release of amoxicillin: The invention relates to liquid pharmaceutical formulations for oral administration with the modified release of amoxicillin, said formulations consisting of suspensions of coated particles of amoxicillin (microcapsules). According to the invention, the microcapsules constituting the disperse phase of the suspension are designed to allow the modified release of the amoxicillin...

20060110465 - Compositions addressing inflammation and/or degenerative disorders: Compositions for primarily addressing degenerative complaints, in particular joint related conditions such as arthritis and rheumatism, in which there may also be associated inflammation, are provided. Other potential uses are also discussed, as well as prophylactic and curative applications. Preferred embodiments incorporate green-lip mussel products (particularly GLME) with shark cartilage...

20060110466 - Natural water wipes: The natural water wipe is unlike others in this category because it is devoid of any added substance, active ingredient or solution. Water will be the only natural ingredient used to avoid irritation or allergic reactions to the skin or to any body parts such as the mouth, eyes, ears...

20060110467 - Cancer chemotherapy: e

20060110469 - Angelicae sinensis extracts useful for treatment of cancers: The invention provides an acetone extract, chloroform extract or hexane extract of Angelicae sinensis and/or the active components purified therefrom, such as n-butylidenephthalide, which are effective in treating cancers....

20060110468 - Herbal formulations for arthritis: The present invention provides an oral formulation comprising ingredients extracted from Caulis Sinomenii, Radix Aconiti Lateralis Preparata, Radix Paeoniae Alba, Cortex Moutan, and Rhizoma Curcumae Longae. The formulation has anti-arthritic, anti-inflammatory and anti-nociceptive properties and is suitable for the treatment of arthritis, symptoms associated with arthritis and other similar conditions....

20060110470 - Pharmaceutical formulation of traditional chinese medicine for abstinence of drug and preparation method and use thereof: The present invention relates to compound Chinese medicine preparation, and is especially one drug addiction stopping Chinese medicine prepared with red sage, mankshood, cassia, amomum fruit and other Chinese medicinal materials. The present invention also discloses its preparation process and application....

20060110471 - Essential oil blend for inhalation: The present invention provides a novel blend of essential oils and herbs. A blend of the invention may be used to treat nausea. A blend of the invention may be used to provide a calming, soothing feeling. Optionally the novel blend of the invention is introduced into the body of...

20060110472 - Use of allicin as insect repellent and insecticide in agricultural crops: The invention provides methods for: (a) protecting agricultural crops, particularly fruits and vegetables, against insects, by treating the crops with allicin prior to harvesting; (b) protecting fruits and vegetables from decay and extending the shelf life thereof by treating the fruits and vegetables with allicin after harvesting; and (c) repelling...

20060110477 - Composition and method for supporting and promoting healthy sexual function and prevention and treatment of sexual dysfunction: Improved nutraceutical compositions and methods for supporting and promoting healthy sexual function, for preventing sexual dysfunction, or for treatment of sexual dysfunction. The compositions include a portion of the plant Sophora flavescens or an extract of the plant Sophora flavescens, such as sophoflavescenol. The compositions also include Vitex agnus-castus extract,...

20060110475 - Composition containing in combination at least one bourd oil and at least one borage oil, use thereof as medicine, as dermatological or dermato-cosmetic agent: The present invention relates to a composition comprising, in combination: at least one marrow oil and at least one borage oil. The invention also relates to such a composition, for its use as a medicinal product, as a dermatological or dermocosmetic agent, or as a nutraceutical agent, especially for its...

20060110473 - Composition containing radix codonopsis pilosulae and radix astragali and hedysari, method of producing it and use thereof: The invention discloses a composition containing radix Codonopsis pilosulae and radix Astragali and hedysari, The main component is made from radix Codonopsis pilosulae and radix Astragali and hedyyari in certain rate. The invention also discloses the method of producing it and the use for producing immune system-regulated agent and these...

20060110478 - Delivery system and method for supporting and promoting healthy sexual function and prevention and treatment of sexual dysfunction: Improved delivery systems and delivery methods for supporting and promoting healthy sexual function, for preventing sexual dysfunction, or for treatment of sexual dysfunction. A compositions including one or more cGMP-specific PDE5 inhibitors and/or dopaminergic agonists is administered in the form of a breath-care strip, mint or lozenge, or a food...

20060110476 - Dietary foodstuff for positively influencing cardiovascular health: This invention relates to a dietary foodstuff containing at least one carob product, particularly water-insoluble carob fibers, and at least one n-3 fatty acid. The invention also relates to a method for producing active substance combinations of this type and to the use thereof....

20060110474 - Rubrofusarin glycoside-containing composition: There is provided an oral composition capable of strimulating intracellular biosynthesis of glutathione in order to maintain in-vivo (i.e., in tissues and cells) glutathione level at a high level, by adding an active ingredient other than an amino acid precursor from a viewpoint of increasing intracellular glutathione synthesis, as a...

20060110479 - Natural composition for curing hepatitis-b, methods for making the same and pharmaceutical formulations thereof: Disclosed herein is a natural antiviral composition comprising extracts of plant Cyperus rotundus and/or plant Cyperus scariosus and a pharmaceutically acceptable carrier. Also disclosed are methods of making the plant extract, methods for preparing the composition and methods of treating diseases related to acute and chronic hepatitis B and other...

20060110480 - Pharmaceutical composition comprising extracts of radix clematidis for treating and preventing diabetes, diabetic complications, insulin resistance and insulin resistance syndrome: Disclosed is a composition comprising extracts of Radix Clematidis for preventing and treating diabetes, diabetic complications, insulin resistance and insulin resistance syndrome. The composition of the present invention for preventing and treating diabetes, diabetic complications, insulin resistance and insulin resistance syndrome, comprises extracts of Radix Clematidis in an amount of...

20060110481 - Compositions containing vitex agnus-castus berry oil for cosmeceutical applications and method of isolation of the active component: The invention relates to the effective use of compositions containing a specially prepared oil from Vitex agnus castus berry as a potent anti-acne agent which is to be applied topically. The invention also describes the process of fractionation of the oil, identification of the active component using bioautographic technique, and...

20060110482 - Transmucosal oral delivery device: Provided, among other things, is a method of treating an indication of mucosal or adjacent tissue comprising periodically applying to mucosa at or adjacent to disease affected tissue a delivery device comprising a backing layer and an adhesive reservoir comprising an effective amount of appropriate composition of plant extract(s) comprising...

20060104897 - Method for diagnosing and treating nis-expressing carcinomas and metastases: The present invention relates to a method for diagnosing and/or treating sodium-iodide symporter (NIS)-expressing primary carcinomas and metastases, preferably glandular carcinomas, in particular carcinomas of the thyroid, of the salivary gland, of the uterus and carcinomas of the breast, and to a pharmacological composition comprising substances which induce and/or increase...

20060104898 - Ligands to radiation-induced molecules: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor...

20060104899 - Production and use of novel peptide-based agents for use with bi-specific antibodies: The present invention relates to a bi-specific antibody or antibody fragment having at least one arm that is reactive against a targeted tissue and at least one other arm that is reactive against a linker moiety. The linker moiety encompasses a hapten to which antibodies have been prepared. The antigenic...

20060104900 - Polymer precursors of radiolabeled compounds, and methods of making and using the same: One aspect of the present invention relates to novel compounds that can be used to prepare radiolabeled compounds in an effective manner. A second aspect of the present invention relates to a method of synthesizing radiolabeled compounds....

20060104902 - Method of preselection patients for anti-vegf, anti-hif-1 or anti-thioredoxin therapy: The present invention generally relates to methods of preselecting patients for treatment with an anti-VEGF therapy, anti-HIF-1 therapy or anti-thioredoxin therapy. Aspects of the invention combine methods of dynamic contrast enhanced-MRI and diffusion weighted-MRI for the detection of tumor histology. The methodology disclosed herein detects tissue blood volume, tumor vascularity,...

20060104901 - Preventing or treating epithelial tissue damage or hair loss: The present invention pertains to a method for preventing and/or treating epithelial tissue damage, such as is effected by inflammatory reactions, ageing or cancer and/or to prevent and/or treat hair loss. In particular, the present invention relates to substances and/or compositions modifying, in particular blocking endogenous CD1d function. According to...

20060104904 - Method of evaluating plant protection: A method is provided for evaluating a protected plant having a protection mechanism. A population of immature insects (i.e., larvae or nymphs) belonging to an insect species having a plurality of instars is first exposed to the protected plant such that the protected plant is at least contacted thereby. The...

20060104905 - Methods of screening agents for activity using teleosts: The present invention provides methods of screening an agent for activity using teleosts. Methods of screening an agent for angiogenesis activity, toxic activity and an effect cell death activity in teleosts are provided....

20060104903 - Model for evaluating the efficacy of locally applied antiproliferatives or other agents on neointimal hyperplasia, immunohistochemical and vascular cell cycle changes in balloon-injured rat carotid arteries: A methodology for evaluating the efficacy of locally applied antiproliferatives and/or other therapeutic agents on neointimal hyperplasia, as well as immunohistochemical and vascular cell cycle changes, in balloon-injured rat carotid arteries may be utilized for determining the efficacy of treatments in humans....

20060104906 - Method and apparatus for producing contrast agents for magnetic resonance imaging: The present invention relates to an arrangement and a method for providing contrast agent for e.g. MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) applications. The method according to the invention comprises the steps of obtaining (100) a solution in a solvent of a hydrogenatable, unsaturated substrate compound and...

20060104908 - Polymerization method for the synthesis of polypeptide imaging agents: A method for synthesizing extended poly(amino acids) conjugated to imaging agents, such as DTPA, is disclosed. The amino acid is initially conjugated to the imaging agent at the monomer stage, followed by formation of the corresponding N-carboxyanhydride. The method utilizes catalyzed ring opening polymerization of the N-carboxyanhydride of the amino...

20060104907 - Biologically potent analogues of the dmt-tic pharmacophore and methods of use: m

20060104909 - Abuse-resistant pharmaceutical compositions: An abuse-resistant controlled release pharmaceutical composition comprising a pharmaceutically effective amount of discrete particles of an active capable of abuse, wherein surfaces of said particles are wetted with a water insoluble coating material, and preferably wherein said composition comprises a matrix, in which said particles are distributed, and which renders...

20060104910 - Over dosage indicating medicated film strip: A stack of at least two layers of an edible film comprising overlying and underlying film layers; each edible film contains a unit dosage of medication; each film within said stack having a unique marking, shape, cut-out, wording, color, texture, or other indicia such that when one or more adjacent...

20060104914 - Device and method for treatment of eyelid diseases: A container has an impermeable outer membrane sized to fit generally within the peri-orbital region and sufficiently flexible to mold to the structure of the closed eye. Heat which is generated by an exothermic reaction inside the container, which provides steady-state heat to the eyelids. A soft, non-abrasive, lint-free material...

20060104911 - Foamable alcohol: The present invention is a foamable alcohol having at least one active ingredient. The active ingredient can be a prescription or non-prescription drug or medication. It either works on the skin or is absorbed transdermally and works on the body. Alcohol, such as ethyl alcohol is combined with a fluoro-surfactant,...

20060104913 - Inhalable formulations for treating pulmonary hypertension and methods of using same: The present invention is directed to an inhalable formulation for the treatment of pulmonary hypertension in a mammal (e.g., humans), wherein the formulation comprises at least one hypertension reducing agent, including but not limited to an angiotensin converting enzyme inhibitor, angiotensin receptor blocker, beta-blocker, calcium-channel blocker or vasodilator, or any...

20060104912 - Mousse composition: A pharmaceutical aerosol foam composition including an effective amount of a pharmaceutically active ingredient; an occlusive agent; an aqueous solvent; and an organic cosolvent, the pharmaceutically active ingredient being insoluble in both water and the occlusive agent; the occlusive agent being present in an amount sufficient to form an occlusive...

20060104915 - Aerosol dentifrice formulation: An aerosol dentifrice formulation is provided comprising a high water based system, a specific particle size abrasive and a liquified gas propellant, characterised in that the liquified gas comprises 2-8 wt % of a non-hydrocarbon and 2-6 wt % of a hydrocarbon propellant. There is provided a dentifrice formulation comprising...

20060104916 - Method and apparatus for enhanced size reduction of particles: The present invention provides methods and apparatus for producing particles via supercritical fluid processing. In one embodiment, the method includes expanding a supercritical fluid plasticized melt across a pressure drop to form solid composite particles that are simultaneously dispersed, foamed and cooled, and milling the solid particles produced to achieve...

20060104917 - Stable pharmaceutical products: Provided herein is a stable pharmaceutical product comprising a dry powder inhalation device, and a pharmaceutical composition that comprises R,R-Formoterol L-tartrate salt, in particular crystalline R,R-formoterol L-tartrate; and ciclesonide....

20060104918 - Antiperspirant aerosol compositions: A suspension antiperspirant aerosol composition comprising milled activated aluminium chlorohydrate (AACH) having non-hollow particles and a carrier fluid comprising a masking oil of viscosity 103 mm2/s or greater gives good antiperspirancey and reduced levels of white deposits....

20060104919 - Foamable alcohol: The present invention is a foamable alcohol health, beauty, skin care, nail care and/or haircare product. Alcohol, such as ethyl alcohol is combined with a fluoro-surfactant, at least one active ingredient and water. Other ingredients can be added. The fluoro-surfactant reduces the surface tension of the alcohol allowing it to...

20060104920 - Flavored hemostatic and acid etching compositions: Hemostatic compositions and dental etching compositions for oral use include methyl salicylate in order to mask or disguise their otherwise unpleasant taste. The methyl salicylate, hemostatic and/or dental etching agent are dispersed within an aqueous carrier, which may be liquid or viscous as desired. In order to increase the stickiness...

20060104921 - Novel gum delivery systems and methods of making thereof: A substrate having about 0.5 wt % to about 25 wt % gum incorporated upon it is provided that provides the benefit of delayed viscosity when incorporated into a person care composition such as a toothpaste. Also disclosed is a method for forming gum incorporated onto or into a substrate...

20060104922 - Tooth whitening compositions and methods for using the same: A tooth whitening system that effectively conceals tooth discoloration within a short period of time. The system includes a single, spectrally pure, substantially violet dye and a carrier for applying the dye to teeth....

20060104925 - Particle comprising a host lattice and a guest, its preparation and use in ultraviolet light screening compositions: A UV screening composition comprising novel particles which are capable of absorbing UV light so that electrons and positively charged holes are formed within the particles is disclosed. These particles comprise a host lattice incorporating a second component to provide luminescence trap sites and/or killer sites, said second component being...

20060104924 - Photostable photoprotective compositions comprising dibenzoylmethane and arylalkyl benzoate compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s): Topically applicable, improvedly photostabilized, photoprotective cosmetic/dermatological compositions contain (i) an effective UV-screening amount of at least one dibenzoylmethane sunscreen and an effective photostabilizing amount of (ii) at least one arylalkyl benzoate compound and (iii) at least one compound accepting the excited triplet level energy of said at least one dibenzoylmethane...

20060104923 - Sunscreen compositions containing fluorinated alkyl ethers: Disclosed are sunscreen compositions containing at least one sunscreen agent, a volatile solvent comprising a cosmetically acceptable lower alkanol, and a fluorinated alkyl ether, and methods of making and using same....

20060104927 - Compound, process for producing the same and use thereof: The compound of the present invention is a component originated from a natural material, camu camu (Myrciaria dubia), has strong antioxidative activity and stable whitening effect, and is represented by the formula (1). The antioxidant, whitening agent, skin preparation for external use, cosmetics, and food of the present invention are...

20060104926 - Whitening agent, skin preparation for external use and cosmetic: The invention relates to a whitening agent that makes effective use of camu camu seeds, which have conventionally been discarded, and that has high safety and whitening effect useful in cosmetics and the like, as well as skin preparations for external use and cosmetics containing the whitening agent. The whitening...

20060104929 - Aqueous emulsion comprising an organosilicon polymer, process for producing the same and cosmetic materials: An aqueous emulsion comprises as the disperse phase obtained by emulsifying a mixture consisting of (A) a linear organosilicon polymer whose main chain is composed of diorganosiloxane units and alkylene units and (B) an oil that is liquid at room temperature. The emulsion can be produced by emulsifying a mixture...

20060104930 - Use of hydrophilic-rich alkylmethylsiloxane-dimethylsiloxane-polyoxyalkylene copolymers as emulsifiers for the preparation of cosmetic o/w emulsions of improved aesthetic properties and mildness:

20060104938 - Methods of setting up, caring for and later removing a temporary rasta hairstyle: A method of setting up, caring for and later removing a temporary rasta hairstyle is disclosed. This method includes applying a roughness-increasing substance to the hair to roughen the hair, optionally, but preferably, applying an adherence-increasing substance to the hair to increase adherence of hairs to each other, and subsequently...

20060104931 - Cosmetic treatment article comprising substrate and gel composition: Disclosed are cosmetic treatment articles comprising: (1) a water-insoluble substrate; (2) a gel composition comprising: (a) a first gel forming composition comprising a water soluble polymeric gelling agent and (b) a second gel forming composition comprising a gel strengthening agent; and (3) preferably, a treatment composition comprising a rheology modifier....

20060104932 - Exfoliating skin care product: Exfoliating skin care products which rapidly dissolve in water, yet are non-irritating to the skin, are provided. These exfoliating skin care products comprise a water soluble particulate material of a large enough particle size such that the user of the exfoliating skin care product can tactilely feel the particulate material...

20060104933 - Process for preparing scented cellulosics and products prepared thereby: The present invention provides a process for optimizing the fragrance of a scented cellulosic....

20060104935 - Controlled dissolution crosslinked protein crystals: The present invention relates to crosslinked protein crystals characterized by the ability to change from insoluble and stable form to soluble and active form upon a change in the environment of said crystals, said change being selected from the group consisting of change in temperature, change in pH, change in...

20060104934 - Cosmetic composition comprising ubiquitin: The invention relates to a cosmetic composition comprising ubiquitin in combination with a cosmetically-acceptable medium....

20060104936 - Charging/separating cosmetic makeup compositions for keratin fibers: The present invention relates to a cosmetic composition for making up keratin fibers, characterized in that it comprises at least one wax, in that it has a solids content of greater than or equal to 45.5% by weight and a plateau Gp modulus of rigidity of greater than or equal...

20060104928 - Thermal hair straightening and conditioning composition: A thermal hair straightening and conditioning composition and method for rendering hair more manageable, minimizing static charge, tangling, and scattering of the hair is disclosed. A gelatinous aqueous thermal hair straightening and conditioning composition is provided that imparts a firm and silky look and feel to hair and inhibits wind...

20060104937 - Scalp treatment: A composition for topical application to the scalp comprises (i) an anti-dandruff agent; (ii) conjugated linoleic acid; and (iii) a cosmetically acceptable diluent or carrier....

20060104939 - Degrading lignocellulosic materials: A method for the degradation of lignocellulosic material by applying to the material an enzyme composition which is a mixture comprising at least a cellulase, xylanase and ligninase, and optionally other enzymes, such as a protease, lipase, urease, uricase, and/or pectinase, to solubilise or decompose the material at least partially....

20060104940 - Cosmetic, pharmaceutical and dermatological preparations comprising copolymer waxes: Cosmetic, pharmaceutical and dermatological preparations are described which contain copolymer waxes. The copolymer waxes contain structural units which are formally derived from α-olefins having 26 to 60 carbon atoms, derivatives of (meth)acrylic acid such as esters, amides or salts and optionally further monomers....

20060104941 - Systemic inflammatory markers as diagnostic tools in the prevention of atherosclerotic diseases and as tools to aid in the selection of agents to be used for the prevention and treatment of atherosclerotic disease: The invention involves methods for characterizing an individual's risk profile of developing a future cardiovascular disorder by obtaining a level of the marker of systemic inflammation in the individual. The invention also involves methods for evaluating the likelihood that an individual will benefit from treatment with an agent for reducing...

20060104942 - Remedies for ischemic disease<