Drug, bio-affecting and body treating compositions inventions 01/06

20060018826 - Biologic modulations with nanoparticles: Certain aspects of the invention relate to the use of small particles in biological systems, including the delivery of biologically active agents to cells or tissues using nanoparticles of less than about 200 nm in approximate diameter. Embodiments include collection of particles having a bioactive component, a surfactant molecule, a...

20060018827 - Positron therapy of inflammation, infection and disease: This invention provides methods for positron therapy of inflammation, infection and disease which comprise administering to a subject a positron emitter or an agent labeled with a positron emitter, wherein the positron emitter or agent binds to or is taken up by affected tissue or by cells at the site...

20060018825 - Probe for diseases with amyloid accumulation, amyloid-staining agent, remedy and preventive for diseases with amyloid accumulation and diagnostic probe and staining agent for neurofibrillary change: The present invention provides compounds having high affinity for amyloid β-protein which are for the diagnosis of diseases in which amyloid β-protein accumulates, for agents for specifically staining amyloid β-protein, and for the treatment and/or prophylaxis of diseases in which amyloid β-protein accumulates. The present invention also provides probes and...

20060018828 - Liposome-containing radiographic contrast medium and preparation method thereof: A method of pereparing a rediographic contrast medium containing liposomes is disclosed, comprising (a) dissolving a phospholipid and a sterol in a supercritical or subcritical carbon dioxide in the presence of a compound containing a hydroxyl group or a polyalkyleneoxide group, (b) adding thereto an aqueous solution containing an iodine...

20060018829 - Cellular receptors utilized as carrier agents for pharmaceutical compounds used in tumor imaging and cancer treatment: A method whereby non-immunogenic intraspecies proteins are used as carrier compounds to deliver imaging agents and pharmaceutical drugs to tumors in the human patient. This invention describes the propensity of certain solubilized cellular receptor proteins to localize in necrotic or inflamed areas of tumors but not in healthy normal tissues....

20060018830 - Gastrin releasing peptide compounds: wherein R1-R5 and FG are as defined herein (in the form complexed with a metal radionuclide or not), N—O—P is the linker containing at least one non-alpha amino acid with a cyclic group, at least one substituted bile acid or at least one non-alpha amino acid, and G is the...

20060018831 - Tf binding agent and use thereof: This invention relates to novel compounds, which bind to tissue factor and the use thereof for diagnostic and/or therapeutic purposes....

20060018832 - Methods of marking and testing pharmaceutical products: Methods of marking pharmaceutical products for use in clinical trials and for determining the origin or authenticity of the marked products are provided that use a variety of natural materials as markers. The natural materials have unique genetically controlled micromorphological structures that can be identified using enhanced visualization techniques. For...

20060018834 - Imaging sexual response: The present invention relates to methods for contrast-enhanced imaging of sexual response. In particular, the present invention relates to methods of magnetic resonance imaging (MRI), computerized X-ray tomography (CT), ultrasound, and optical imaging using contrast agents to measure blood flow during sexual response, especially female sexual response. The invention relates...

20060018833 - Method and system for screening compounds for muscular and/or neurological activity in animals: Screening methods and instrumentation for candidate pharmacological agents are applied to discover compounds with muscular and/or neurological activity. The method comprises the use of teleost fish, such as the medaka (Oryzias latipes), which may be stimulated with chemical agents or an electric field to produce, for example, seizure activity and/or...

20060018835 - Nanoparticles with inorganic core and methods of using them: An aspect of the invention includes a nanoparticle including a substantially monodisperse inorganic core with a surface and a coating substantially covering the surface of the substantially monodisperse inorganic core, wherein the coating includes of at least coating structure I, II, or III wherein the nanoparticle is substantially non-agglomerated and...

20060018836 - Method for treating human tumor cells with a newcastle disease virus strain having a p53 independent oncolytic effect: A method for treating p53-negative human tumor cells to induce apoptotic cell death thereof includes the step of infecting the tumor cells with the Herefordshire strain of Newcastle disease virus. The MOI is in the range of 100/1 to 1/200 cell/infected particle ratio....

20060018837 - Pharmaceutical compositions and methods for the prevention of drug misuse: A pharmaceutical composition including a therapeutic dose of an active ingredient susceptible of either intentional or accidental misuse by over-utilization and a sub-therapeutic dose of a compound in an amount sufficient to elicit an undesirable response if the recommended therapeutic dose of the active ingredient is exceeded....

20060018838 - Vacsularized tissue for transplantation: Tissue engineering holds enormous potential to replace or restore function to a wide range of tissues. However, the most successful applications have been limited to thin avascular tissues in which delivery of essential nutrients occurs primarily by diffusion. Pursuant to the present invention, a prevascularized, thick tissue construct is created...

20060018840 - Aerosolizable formulation comprising nicotine: An aerosolizable formulation comprises free-base nicotine, an organic acid, and a hydrofluoroalkane propellant. The organic acid is present in a mole ratio with said nicotine in a range of about 0.25:1 (organic acid:nicotine) to about 4:1 (organic acid:nicotine). The organic acid and said free-base nicotine form a nicotine salt. An...

20060018839 - Methods and compositions using cholinesterase inhibitors: The invention provides methods for treating and/or preventing Alzheimer's disease, psychiatric illnesses, encephalitis, meningitis, fetal alcohol syndrome, Karsakoff's syndrome, anoxic brain injury, cardiopulmonary resuscitation injuries, diabetes, Sjogren's syndrome, mental retardation, developmental delay, menopause, strokes, macular degeneration, neuronal loss associated with macular degeneration, sleep disorders, severe Alzheimer's disease, jet lag, post-traumatic...

20060018841 - Aav vectors for gene delivery to the lung: Methods of making and using recombinant AAV vectors and virions for gene delivery to the lung are described. The recombinant AAV virions are derived from caprine AAV and bovine AAV, both of which display tropism for lung tissue....

20060018842 - Composition and method for delivery of phytochemicals: Anti-microbial and anti-cancer phytochemicals can be delivered with a composition comprising an phytochemical, in which the composition allows the controlled release of the phytochemical upon administration of the composition to a subject. The phytochemicals can be delivered as a nutritional supplement, or for the treatment or prevention of cancer or...

20060018843 - Halitosis, gingivitis, and periodontitis treatment and preventative composition: Disclosed is a composition and method for the treatment and prevention of bad breath, halitosis, gingivitis, and/or periodontitis that contains one or more varieties of probiotic bacteria from the groups Lactobacillus, Bacillus, Escherichia, Enterococcus, Streptococcus, and Bifidobacterium, and/or a species of the yeast genus Saccharomyces. The composition may be in...

20060018844 - Botulinum toxin dental therapy for angular cheilosis: Methods for treating an angular cheilosis and/or a lip positioning abnormality by administration of a botulinum toxin to a patient....

20060018845 - Tooth whitening: wherein; R is H, C1-6 alkyl, (C1-6 alkylO)mR2, or —C(O)R1, wherein at least one R is H, one R is C1-6 alkyl or (C1-6 alkylO)mR2, and one R is —C(O)R1; R1 is C5-10 aryl or C1-6 alkyl, optionally substituted with at least one CO2H; R2 is H or C(O)R1; m...

20060018847 - Active ingredient combinations of polyhexamethylenebiguanidine hydrochloride and distearyldimethylammonium chloride and preparations comprising said active ingredient combinations: The invention is an active ingredient combination comprising polyhexamethylenebiguanidine hydrochloride and distearyldimethylammonium chloride and a cosmetic or dermatological formulation comprising polyhexamethylenebiguanidine hydrochloride and distearyldimethylammonium chloride. The invention also includes methods of fighting or preventing dermatological harm comprising applying to the skin a cosmetic or dermatological formulation comprising polyhexamethylene biguanidine hydrochloride...

20060018846 - Animo substituted hydroxyphenyl benzophenone derivatives: Described are amino substituted hydroxyphenyl benzophenone derivatives of formula (I), wherein R1, and R2 independently from each other are; C1-C20alkyl; C2-C20-alkenyl; C3-C10cycloalkyl; C3-C10cycloalkenyl; or R1, and R2 together with the linking nitrogen atom form a 5- or 6-membered heterocyclic ring; n1 is a number from 1 to 4; when n1=1,...

20060018849 - Cosmetic or dermatological preparations of the oil-in-water type: in which R1, R2 and R3, independently of one another, are chosen from the group consisting of ethyl, propyl and butyl, and R4 is a hydrogen atom or a CH3(CO) group; and a water phase, where the difference in density between the oil phase and the water phase (determinable using...

20060018848 - Photoprotective compositions comprising methyltrialkylsilanes containing a cinnamate, cinnamamide, benzalmalonamide or benzalmalonate function: Unique photoprotective compositions contain novel methyltrialkylsilanes bearing a cinnamate, cinnamamide, benzalmalonamide or benzalmalonate function, useful as sunscreens that are active in the field of UV radiation....

20060018850 - Fungicidal gel and method for controlling nail fungi: A gel formulation is combined with a fungicidal concentrate which is a liquid mixture of about 1.2 to 16 ml parts by volume of ultra pure water having an electrical resistance of 16-26 megohms, total dissolved solids of less than 0.04 parts per million and a specific conductance of less...

20060018852 - Compositions containing topical active agents and pentylene glycol: Disclosed are cosmetic and dermatological compositions containing hydrocortisone or a derivative thereof, a glycol and a thickening or gelling agent, and methods of making and using them....

20060018851 - Methods and compositions for preventing and treating hyperpigmentation of skin: Disclosed are methods for treating hyperpigmentation of skin employing topical application of compositions which comprise at least one peptide manganese complex. Also disclosed are methods wherein the composition further comprises retinol, at least one retinol derivative, or a mixture thereof and methods wherein the composition further comprises active agents selected...

20060018854 - Cosmetic compositions: The present disclosure relates to a cosmetic composition comprising at least one composite pigment, the composite pigment comprising an inorganic core at least partially coated with at least one organic coloring substance, wherein the mean gloss T0h of the composition is not less than 30....

20060018853 - Cosmetic pack preparation: A cosmetic pack preparation comprising (a) 5-20 wt % of polyvinyl alcohol and (b) 0.01-10 wt % of atitanium-titanium dioxide sinter is disclosed. The cosmetic pack preparation enables distinct identification of areas which the cosmetic composition was applied to or was peeled from and the skin cleaning effect, imparts a...

20060018855 - Cosmetic method and composition: An aqueous antiperspirant or deodorant oil in water emulsion suitable for being dispensed through a roll-on exhibiting superior consumer attributes and comprising a continuous aqueous phase containing an antiperspirant or deodorant active, an ethoxylated ether emulsifier or mixture having an average HLB of from 7 to 9 and a dispersed...

20060018856 - Siloxane polymers with quadruple hydrogen bonding units: The invention relates to the synthesis of siloxane polymers containing self-complementary quadruple hydrogen bonding groups (4H-units). The resulting polymers show unique new characteristics that result from the reversible, physical interactions between the polysiloxane chains that are based on the (supramolecular) interactions between the 4H-units. The polysiloxanes in this invention show...

20060018867 - Cosmetic composition and production thereof: It has been desired to develop a highly preservative and antibacterial cosmetic composition that can easily be applied to both emulsion and non-emulsion type cosmetics. It has also been desired to develop a method of improving a preservative and/or antibacterial effect(s) of a cosmetic composition comprising polyorganosiloxane-containing epsilon-polylysine and thereby...

20060018857 - Conditioning surface-active preparation: in which R1 is a linear or branched alkyl or alkenyl group containing 6 to 22 carbon atoms and n is a number of 1 to 50, (c) 0.005 to 1.5% by weight of at least one alkaline earth metal ion and (d) 0.1 to 3% by weight of a...

20060018858 - Skin care composition: Disclosed is a skin care composition comprising: (1) from about 0.001% to about 10% of a flavonoid compound; (2) from about 0.01% to about 15% of a vitamin B3 compound; and (3) a dermatologically acceptable oil continuous phase carrier....

20060018859 - Modified human serum albumin with reduced or eliminated affinity to chemical or biological contaminants at cys 34: A modified serum albumin is provided which has been modified at position cysteine 34 of human serum albumin, or at equivalent locations in other mammalian serum albumins, with an amino acid which lacks a sulphydryl group and will thus be less reactive with biological or chemical molecules such as trace...

20060018860 - Skin care composition: Disclosed is a composition comprising: (1) from about 0.001% to about 10% of a flavonoid compound; (2) from about 0.01% to about 15% of a vitamin B3 compound; and (3) a dermatologically acceptable single aqueous phase carrier....

20060018861 - Skin care composition: Disclosed is a skin care composition comprising: (1) from about 0.001% to about 10% of a flavonoid compound; (2) from about 0.01% to about 15% of a vitamin B3 compound; and (3) a dermatologically acceptable oil-in-water carrier comprising at least about 2% by weight of the entire composition of an...

20060018862 - Substrate based skin care device: Disclosed is a skin care device comprising: (1) a dermatologically acceptable preformed substrate and (2) a flavonoid compound, wherein the device comprises a liquid medium for delivering the flavonoid compound....

20060018863 - Novel ethylenic copolymers, compositions and methods of the same: The present disclosure relates to novel ethylenic copolymers comprising from 10% to 80% by weight, of at least one monomer of polyethylene glycol (meth)acrylate type, from 20% to 90% by weight, of at least one anionic monomer, and from 0% to 70% by weight, at least one additional nonionic hydrophilic...

20060018864 - Cosmetic preparation containing glycerylamino acid derivative: Skin care cosmetics, such as lotions, creams and milky lotions, and hair cosmetics, such as hair creams, hair conditioners, hair rinses and shampoos, being excellent in moisturizing effect, applicability, stability and safety and characterized in containing an amino acid N-glyceryl derivative produced by reacting neutral, basic or acidic α-amino acid...

20060018865 - Foaming cleansing composition: A cleansing composition for topical application containing at least one surfactant chosen from alkyl glycol carboxylic acids and their salts, and at least one surfactant chosen from monoalkyl phosphates, dialkyl phosphates and their salts. The composition has good cosmetic properties, and the foam obtained is fine and rinses off well....

20060018866 - Oil-in-water emulsified composition: (C) an acid compound selected from the group consisting of inorganic acid or an organic acid having 5 or less carbon atoms, and (D) cholesterol or phytosterol, wherein the ratio of a liquid oil component containing Component (A) in the total amount of oil phase is 5 to 90 wt...

20060018869 - Cosmetic or dermatological preparation with a content of creatine, creatinine or derivatives thereof in combination with soybean germ extract: The invention is a cosmetic or dermatological preparation with a content of an active agent combination comprising (a) at least one creatinine compound selected from the group consisting of creatinine and derivatives of creatinine; (b) at least one creatine compound selected from the group consisting of creatine and derivatives of...

20060018868 - Use of a cotton honeydew extract as active ingredient in or for preparing a cosmetic and/or pharmaceutical composition: The invention concerns the use, as active principle, in or for preparing a composition, of an efficient amount of at least one extract of cotton honeydew, the extract or the composition being designed for care of keratinous substrates. The invention also concerns a cosmetic and/or pharmaceutical composition containing said extract,...

20060018870 - Rigid polymer and method of making same: A rigid polymer has: a homopolymer of one of a polymerizable bio-derived rigid compound having two or more reactive functional groups, a derivative of the bio-derived rigid compound, a hydrolyzed substance of the bio-derived rigid compound, a derivative of the hydrolyzed substance of the bio-derived rigid compound and the substances...

20060018871 - Aptamer therapeutics useful in the treatment of complement-related disorders: The invention provides nucleic acid therapeutics and methods for using these nucleic acid therapeutics in the treatment of complement-related disorders....

20060018872 - Poly(lactic acid) copolymer hydrogels and related methods of drug delivery: A-B-A triblock copolymers tailored to produce certain embodiments that have specific properties, such as relatively high elastic modulus. Also provided are methods of designing and synthesizing such a triblock copolymer having desired properties, such non-limiting copolymers comprising a poly(ethylene oxide) block and a block selected from at least one of...

20060018873 - Peptides of il-2 and derivatives thereof and their use as therapeutic agents: The present invention relates to new peptides of IL-2, and derivatives thereof and their use as therapeutic agents....

20060018874 - Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof: Fatty acid compositions for administration of of pharmaceutical agents, such as proteins and peptides, protein and peptide conjugates, and/or cation-polypeptide conjugate complexes. In particular, the invention provides a solid pharmaceutical composition formulated for oral administration by ingestion, having from about 0.1 to about 75% w/w fatty acid component, where the...

20060018875 - Interferon compositions and methods of use thereof: The present invention provides compositions, including pharmaceutical compositions, comprising IFN-α and IFN-γ. The present invention further provides methods of treating various disorders, the methods comprising administering an effective amount of a subject composition....

20060018876 - Treatment of diseases caused by viral infection: A method of prophylactic and/or therapeutic treatment of a mammal for a disease that is caused by a Ljungan virus infection, such as Myocarditis, Cardiomyopathia, Guillain Barré Syndrome, and Diabetes Mellitus, Multiple Sclerosis, Chronic Fatigue Syndrome, Myasthenia Gravis, Amyothrophic Lateral Sclerosis, Dermatomyositis, Polymyositis, Spontaneous Abortion, Intrauterine Death, Preeclampsia, Sudden Infant...

20060018878 - Dual antigen specific t cells with trafficking ability: The present invention is directed to mammalian T cells and methods for using these T cells. More specifically, the invention relates to viral specific T cells that express an endogenous viral antigen receptor, a chimeric anti-tumor receptor and the chemokine receptor CCR7. These T cells are a source of effector...

20060018877 - Intradermal delivery of vacccines and therapeutic agents: The present invention relates to methods and devices for administration of vaccines and therapeutic agents into the intradermal layer of the skin. The methods of the present invention elicit increased humoral and/or cellular response as compared to conventional vaccine delivery methods, e.g., intramuscular route. Furthermore, the methods of the present...

20060018881 - Coordinate in vivo gene expression: Nucleic acids, including DNA constructs and RNA transcripts, capable of inducing coordinate expression of two to three cistrons upon direct introduction into animal tissues, are. bi- or tri-cistronic polynucleotides of this invention include those encoding and co-expressing HIV gene products, genes encoding antigens unrelated to HIV, and immunostimulatory gene products,...

20060018879 - Expression vectors for treating bacterial infections: The present invention is compositions and methods for producing anti-bacterial polypeptides, and for using those compositions and methods for treating diseases and conditions caused by a bacterial infection. More specifically, the compositions and methods include treating a gram-negative bacterium with a gram-positive host that produces a polypeptide effective against the...

20060018882 - Medical devices and methods for delivering compositions to cells: The present invention provides medical devices and methods for delivering compositions to cells. The compositions include an artificial viral vector, and particularly, an artificial adeno-associated virus vector. Such compositions can be useful for delivering the artificial viral vector across the blood-brain barrier....

20060018880 - Methods and compositions for delivery of an enhanced response to antigenic substrates: A novel immunostimulating delivery system is disclosed which provides for generation of a specific antibody response and specific T cell response to delivered antigens. According to the invention, the antigen or a nucleotide encoding the same is contained within, impregnated in or associated with a biocompatible collagen based carrier composition....

20060018889 - Methods and compositions for bone marrow stem cell-derived macrophage delivery of genes for gene therapy: The present invention provides an isolated nucleic acid comprising a promoter operably linked to a nucleic acid encoding a peptide or protein and/or an RNA (e.g., antisense or ribozyme), wherein the promoter comprises elements that can include, but are not limited to, a) a myeloid specific promoter element comprising a...

20060018888 - Suicidal mutant leishmania vaccine: The present invention discloses the use of a mutant Leishmania as a suicidal vaccine wherein the mutant Leishmania is responsive to external signals to become porphyric and commit suicidal cytolysis. The mutant can be selected from natural Leishmania species or constructed by genetic engineering....

20060018883 - Microbial preparation & method for preventing and curing the bacterial wilt the plant and its use: Formulations comprising bacterial of non-toxigenic strain Paenibacillus polymyxa or the cell-free filtrate obtained from its culture broth are provided as biological agents for control of plant pathogens. Particularly, the formulation of this invention is effective not only in inhibiting bacterial wilt and other plant diseases such as seedling Rhizoctonia, damping...

20060018890 - Method for preventing or treating respiratory infections and acute otitis media in infants: The present invention is directed to a novel method for preventing or treating respiratory infections and acute otitis media in infants. The method comprises the administration of a therapeutically effective amount of a Bifidobacteria strain and an adherence-promoting probiotic, such as LGG, to the infant....

20060018884 - Method for treating human tumor cells with a newcastle disease virus strain and a chemotherapeutic agent: A method for treating human tumor cells to induce apoptotic cell death thereof includes the step of infecting the tumor cells with a combination of the Herefordshire strain of Newcastle Disease Virus and a chemotherapeutic agent. The range of concentrations of chemotherapeutic agent/Herefordshire strain is in the range of 100/1...

20060018887 - Enhanced adipose tissue: An enhanced adipose tissue containing native adipose tissue and a concentrated amount of an active agent derived from adipose tissue, wherein the enhanced adipose tissue is preferably injected into the intervertebral disc of a patient suffering from degenerative disc disease....

20060018885 - Methods for increasing hsc graft efficiency: This invention demonstrates that FC function via TNF-α to affect function of HSC. FC from TNF-α deficient mice are impaired in facilitating HSC engraftment in both the syngeneic and allogeneic models. Co-incubation of FC with HSC results in significant increase in TNF-α at the mRNA and protein level, and increase...

20060018886 - Modalities for the treatment of degenerative diseases of the retina: This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment epithelium (RPE) cells and other retinal progenitor cells....

20060018891 - Super absorption coenzyme q10: An improved soft gelatin formulation and process methodology that increases single Coenzyme Q10 molecules presented to the absorption channels of the small intestines by providing medium chain triglycerides, Vitamin E and natural beta carotene to Coenzyme Q10 in a soft gel capsule to increase the absorption thereof....

20060018892 - Human serpin polypeptides: This invention relates to Thypin, a new member of the human serpin polypeptide family, methods of making Thypin polypeptides and using these polypeptides to treat various medical disorders and to methods of screening for compounds that agonize or antagonize Thypin polypeptide activities....

20060018893 - Method for determining modulation of p110delta activity: The invention relates to a novel lipid kinase which is part of the PI3 Kinase family. PI3 Kinases catalyze the addition of phosphate to inositol generating inositol mono, di and triphosphate. Inositol phosphates have been implicated in regulating intracellular signaling cascades resulting in alternations in gene expression which, amongst other...

20060018894 - Administration of enoxoparin sodium to patients 75 years and older with st-segment elevation myocardial infarction: Methods for treating ST-segment elevation myocardial infarction in a human patient 75 years of age or older. The methods comprise administering a dose of less than 1 mg per kg body weight, about 0.75 mg per kg of body weight, or 0.75 mg per kg of body weight of enoxaparin...

20060018898 - Antibody variants: This invention relates to an antibody which is modified version of a therapeutic antibody with affinity for a cell-surface antigen, the antibody having reduced affinity for the antigen compared with the therapeutic antibody as a result of a modification or modifications to the antibody molecule, wherein the antibody is capable...

20060018897 - Bispecific antibodies: The present invention provides compositions and methods for targeting stem cells to injured cardiac tissue....

20060018896 - Methods for treating conditions associated with lectin-dependent complement activation: In one aspect, the invention provides methods of inhibiting the effects of lectin-dependent complement activation in a living subject. The methods comprise the step of administering, to a subject in need thereof, an amount of a MAp19 inhibitory agent effective to inhibit lectin-dependent complement activation. In some embodiments, the MAp19...

20060018895 - Murine monoclonal anti-idiotype antibody 11d10 and methods of use thereof: The present invention provides a monoclonal anti-Idiotype antibody 11D10 that elicits an immune response against a specific epitope of a high molecular weight mucin of human milk fat globule (HMFG) and a hybridoma that produces 11D10. The hybridoma that produces 11D10 was selected by specific procedures. 11D10 induces an immunological...

20060018899 - Her2 antibody composition: A composition comprising a main species HER2 antibody that binds to domain II of HER2, and an amino acid sequence variant thereof comprising an amino-terminal leader extension is disclosed. Pharmaceutical formulations comprising the composition, and therapeutic uses for the composition are also disclosed....

20060018900 - Self antigen vaccines for treating b-cell lymphomas and other cancers: A polypeptide self-antigen useful in a tumor-specific vaccine mimics one or more epitopes of an antigen uniquely expressed by cells of the tumor. The polypeptide is preferably produced in a plant that has been transformed or transfected with nucleic acid encoding the polypeptide and is obtainable from the plant in...

20060018901 - Use of antibodies in a very low dose for the vaccination against cancer: The use of an antibody directed against the cellular membrane antigen EpCAM for the production of a pharmaceutical preparation for the prophyactic and/or therapeutic active immunization against cancer is provided whereby the antibody is in an amount of 1 ng to 9 μg....

20060018902 - Antibodies to erythropoietin receptor and uses thereof: The present invention relates to antibodies and antigen-binding portions thereof that bind to and activate an erythropoietin receptor. The invention also relates to nucleic acid sequences encoding such antibodies and antigen-binding portions. The present invention further relates to methods of activating the endogenous activity of an erythropoietin receptor in a...

20060018907 - Anti-tnf antibodies and peptides of human tumor necrosis factor: Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-α (TNFα) and are useful in vivo diagnosis and therapy of a number of TNFα-mediated pathologies and conditions, including ankylosing spondylitis, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods...

20060018904 - Combination therapies utilizing benzamide inhibitors of the p2x7 receptor: t

20060018906 - Methods for treating sarcoidosis using anti-tnf antibodies and fragments thereof: Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-α (TNFα) and are useful in vivo diagnosis and therapy of a number of TNFα-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of...

20060018905 - Methods for treating systemic lupus erythematosus using anti-tnf antibodies and fragments thereof: Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-α (TNFα) and are useful in vivo diagnosis and therapy of a number of TNFα-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of...

20060018903 - Tnf alpha-binding polypeptide compositions and methods: A TNF alpha-binding polypeptide composition comprises at least one of a modified heavy chain variable region polypeptide or a modified light chain variable region polypeptide that is capable of specifically binding to human TNF alpha. The modified heavy chain variable region polypeptide and the modified light chain variable region polypeptide...

20060018909 - Angiopoietin-2 specific binding agents: Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin-2. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods of making and using the antibodies....

20060018910 - Combination treatment for non-hematologic malignancies: The present invention relates to a therapeutic method for the treatment of non-hematologic malignancies comprising administering anti-IGF-1R antibodies, particularly human anti-IGF-1R antibodies, to a patient, in conjunction with the administration of at least one other therapeutic agent. The invention further relates to pharmaceutical compositions comprising these antibodies and methods of...

20060018908 - Compositions and methods for treating cancer: The invention features compositions and methods for treating or alleviating a symptom of cancer. The compositions and methods of the invention direct supra-lethal doses of radiation, called Hot-Spots, to virtually all cancer cell types....

20060018911 - Design of therapeutics and therapeutics: Therapeutic complexes and components of therapeutic complexes are provided herein. Also provided are methods of preparing therapeutic complexes and methods of administering therapeutic complexes....

20060018914 - Novel antibody conjugates reactive with human carcinomas: The present invention relates to novel antibodies, antibody fragments and antibody conjugates and single-chain immunotoxins reactive with human carcinoma cells. More particularly, the antibodies, conjugates and single-chain immunotoxins of the invention include: a murine monoclonal antibody, BR96; a human/murine chimeric antibody, ChiBR96; a F(ab′)2 fragment of BR96; ChiBR96-PE, ChiBR96-LysPE40, ChiBR96...

20060018912 - Snares for pathogenic or infectious agents and uses related thereto: The present invention provides a snare molecules comprising an attachment moiety (which facilitates attachment of a receptor to a cell) and a receptor for a toxic pathogenic or infectious agent, e.g., a virus. Methods of producing such snare molecules and their therapeutic and/or prophylactic uses are also provided by the...

20060018913 - Therapeutic use of anti-tf-antigen antibody: The invention is related to administration of monoclonal antibody JAA-F11 to an individual for inhibition of metastasis and/or inhibition of growth of cells which express TF-Ag, or for detection of tumors or metastatic foci which express TF-Ag. For inhibition of metastasis or inhibition of growth of cells expressing TF-Ag, the...

20060018916 - Compositions and methods for eliciting an immune response to gram-negative bacterial infections: Compositions for eliciting an immune response against Gram-negative bacterial infections and methods of making such compositions are provided. The composition comprises glycosylated pilin, the pilin being glycosylated with the O-antigen of a target Gram-negative bacteria of interest. Methods of eliciting an immune response by administration of such compositions are also...

20060018915 - Heteroclitic analogs and related methods: Heteroclitic analogs of class I epitopes are prepared by providing conservative, semi-conservative, or non-conservative amino acid substitutions at positions 3 and/or 4 and/or 5 and/or 6 and/or 7 and/or 8 and/or 9 and/or 10 of these epitopes. The analogs are useful in eliciting immune responses with respect to the corresponding...

20060018917 - Nucleic acid and corresponding protein named 158p1d7 useful in the treatment and detection of bladder and other cancers: A novel gene (designated 158P1D7) and its encoded protein are described. While 158P1D7 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including set forth in Table 1. Consequently, 158P1D7 provides a diagnostic and/or therapeutic target for cancers. The 158P1D7 gene or fragment thereof,...

20060018918 - Production of stabilized conformational isomers of disease associated proteins: The present invention includes compositions and methods for the development, isolation and characterization of vaccine that include one or more isolated and purified non-native, stabilized conformational protein isomer antigens....

20060018920 - Lawsonia derived gene and related omph polypeptides, peptides and proteins and their uses: The present invention relates generally to therapeutic compositions for the treatment and/or prophylaxis of intestinal disease conditions in animals and birds caused or exacerbated by Lawsonia intracellularis or similar or otherwise related microorganism. In particular, the present invention provides a novel gene derived from Lawsonia intracellularis which encodes an immunogenic...

20060018919 - Peptide mimotopes of lipooligosaccharide from nontypeable haemophilus influenzae as vaccines: The present invention relates to peptide mimotopes of lipooligosaccharide from nontypeable Haemophilus influenzae as vaccines....

20060018921 - Histone deacetylase inhibitors and cognitive applications: The present invention relates to the enhancement of cognition in an individual by delivery of a histone acetylation regulator, such as a histone deacetylase inhibitor. The individual may have normal or poor memory, and the poor memory may be the result of a pathogenic condition or a non-pathogenic condition, such...

20060018922 - Use of recombinant bovine cd14 in the treatment and prevention of coliform mastitis in dairy cows: Studies in mice and humans indicate that membrane CD14 (mCD14) on the cell surface of monocytes, macrophages, and PMN mediates the activation of these cells by LPS. The soluble CD14 (sCD14) present in the circulation also binds to LPS and blocks LPS binding to mCD14. To determine the role of...

20060018923 - Novel human virus causing respiratory tract infection and uses thereof: The present invention provides the complete genomic sequence of a novel human coronavirus, coined as coronavirus-HKU1 (“CoV-HKU1”), isolated in Hong Kong from a patient who had a recent history of visit to Schenzhen, China. The virus belongs to the order Nidovirales of the family Coronaviridae, being a single-stranded RNA virus...

20060018924 - Hyaluronan synthase gene and uses thereof: The present invention relates to a nucleic acid segment having a coding region segment encoding enzymatically active hyaluronate synthase (HAS), and to the use of this nucleic acid segment in the preparation of recombinant cells which produce hyaluronate synthase and its hyaluronic acid product. Hyaluronate is also known as hyaluronic...

20060018925 - Compositions and methods for modulating rsv infection and immunity: Compositions and methods are provided for the treatment or prevention of RSV disease by modulating RSV infection and immunity. In particular, amino acid sequences in the RSV G glycoprotein, containing the chemokine motif defined as C-X-X-X-C (or CX3C), are identified that are essential in causing RSV infection and disease. The...

20060018926 - Noscapine derivatives as adjuvant compositions and methods of use thereof: An adjuvant composition comprising noscapine and its derivatives, for use in the treatment of tumors, cancer, as an adjuvant for vaccines....

20060018927 - Respiratory syncytial virus vaccines expressing protective antigens from promotor-proximal genes: Recombinant respiratory syncytial virus (RSV) having the position of genes shifted within the genome or antigenome of the recombinant virus are infectious and attenuated in humans and other mammals. Gene shifted RSV are constructed by insertion, deletion or rearrangement of genes or genome segments within the recombinant genome or antigenome...

20060018928 - Virus-like particle containing a dengue virus recombinant replicon: The present invention relates virus-like particle vaccine containing dengue virus recombinant replicon as its core and its preparation method. Such vaccine can efficiently express antigen in the infected tells. Because dengue virus can infect dendritic cells, it can efficiently present antigen and has immunity effects. Further, different dengue virus types...

20060018929 - Protein kinase deficient, immunologically active cmvpp65 mutants: This invention relates to mutated CMVpp65, a viral structural protein which activates cell mediated immunity in humans infected with CMV. The mutations remove undesirable protein kinase activity naturally present in the protein and make it suitable for the production of both DNA and protein vaccines. Therefore, the invention provides proteins...

20060018930 - Compositions comprising viruses and methods for concentrating virus preparations: A composition is disclosed comprising virus in a formulation comprising a polyhydroxy hydrocarbon buffered to maintain a pH in a range from about 7 to about 8.5 at a temperature in the range from about 2° C. to 27° C. Methods for concentrating and purifying virus preparations are also disclosed....

20060018931 - Therapeutic composition with a botulinum neurotoxin: The present invention pertains to pharmaceutical compositions which comprise a botulinum neurotoxin from Clostridium botulinum, the neurotoxin being free of the complexing proteins naturally present in the botulinum neurotoxin complex or being chemically modified or being modified by genetic manipulation. Moreover the pharmaceutical compositions of the instant invention have good...

20060018932 - Recombinant protein containing a c-terminal fragment of plasmodium msp-1: The invention relates to a recombinant protein fabricated in a baculovirus system, of which the essential constitutive polypeptide sequence is that of a C-terminal fragment of 19 kilodalton (p19) of the surface protein 1 (protein MSP-1) of the merozoite parasite of the Plasmodium type, particularly Plasmodium falciparum, which is infectious...

20060018933 - Novel drug delivery system: A novel modified release dosage form comprising of a high solubility active ingredient, which utilizes dual retard technique to effectively reduce the quantity of release controlling agents. Present invention can optionally comprise additionally another active ingredient as an immediate release form or modified release form. Present invention also relates to...

20060018934 - Novel drug delivery system: A novel modified release dosage form comprising of a high solubility active ingredient, which utilizes dual retard technique to effectively reduce the quantity of release controlling agents. Present invention can optionally comprise additionally another active ingredient as an immediate release form or modified release form. Present invention also relates to...

20060018936 - Core for cosmetic articles: A cosmetic product core comprises a basic core mass and solid particles dispersed therein. The basic core mass includes at least one fatty acid salt and at least one lipophilic material with a melting temperature range<50° C....

20060018938 - Foam skin cream, use of the foam skin protection cream and a process of its preparation: preparing a phase I by melting at 75° C. a mixture containing fatty acids, especially C12-C22 fatty acids, optionally unsaturated and/or polyunsaturated fatty acids, emulsifiers, coemulsifiers, such as triceteareth-4-phosphate, followed by metering it with stirring to a phase II temperature-controlled at 75° C. obtained from an aqueous mixture containing moisturizers,...

20060018939 - Method for preparing a fluid absorber: Disclosed are a fluid absorber, a method for preparing a fluid absorber, and a method for absorbing fluid from the skin. The disclosed method for preparing a fluid absorber generally comprises the steps of selecting a starch and an enzyme for hydrolysis of the starch, determining a fluid absorption optimum...

20060018935 - Odorless polyether-modified polysiloxane composition, process for the production thereof, and cosmetics containing the same: The deodorized, polyether-modified polysiloxane composition not producing a substance giving off a foul odor, while being produced or stored, which results from hydrolysis, oxidation or the like of a by-product or unreacted material and temporarily stable, a method for producing the same, and a cosmetic containing the same, wherein a...

20060018937 - Steroid kit and foamable composition and uses thereof: A composition and therapeutic kit including an aerosol packaging assembly including a container accommodating a pressurized product and an outlet capable of releasing a foamable composition, including a steroid as a foam. The pressurized product includes a foamable composition including: a container accommodating a pressurized product; and an outlet capable...

20060018940 - Stabilized antimicrobial composition: A composition is disclosed comprising a dissolvable solid containing an active oxygen compound and precursors for chlorine dioxide characterized in that when said solid weighs a total of about 5 grams it dissolves in about 3.8 liters of water at 25° C. in less than 30 minutes, thereby generating an...

20060018943 - Antimicrobial material for implanting in bones: The invention relates to an antimicrobial material for implanting in bones and for coating or producing an implant or an implantable medical device, whereby particles formed from an antimicrobial material are remotely dispersed inside a matrix material that forms a matrix when hardened. In order to improve the compatibility of...

20060018944 - Polycationic peptide coatings and methods of coating implantable medical devices: Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed....

20060018942 - Polymeric microbeads having characteristics favorable for bone growth, and process including three dimensional printing upon such microbeads: The invention includes a method of three dimensional printing comprising manufacturing microbeads by an emulsion solvent extraction/evaporation process, followed by three dimensional printing onto powder layers comprising the microbeads. The invention also includes polymeric microbeads containing a bioactive substance or Active Pharmaceutical Ingredient, particularly a substance which stimulates the formation...

20060018941 - System and method for injecting liquid drug containing biological material: A method for injecting a liquid drug containing a biological material is provided, which comprises the step of injecting the liquid drug containing the biological material contained in an injector into a subject at a predetermined range of velocity....

20060018945 - Gallium inhibits biofilm formation: The present invention provides a gallium-containing composition for coating/impregnating a device or device surface to prevent biofilm growth formation. The present invention also provides a method of preventing or inhibiting biofilm growth formation. The present invention also provides methods for killing established biofilms....

20060018946 - Polymer gel containing hyaluronic acid and collagen, and its use in joints: Formulations and methods for treating joints, such as temporomandibular joint disorders, osteoarthritis of the knee, hip and other types of inflammatory joint diseases. The method involves identifying specific matrix metalloproteinases (MMPs) that may be responsible for degrading the soft tissues of the joint in question, identifying the specific component of...

20060018948 - Biodegradable implantable medical devices, methods and systems: The invention provides implantable intraluminal medical devices that are fabricated of biodegradable materials. The invention further provides methods of treatment utilizing the devices....

20060018947 - Bioresorbable nerve guide rail: A biologically resorbable nerve guide rail with a microporous guide tube of polymers of hydroxycarboxylic acids, where the porosity allows a metabolism through the tube wall, but prevents the passage of cells, and optionally several monofilaments of polymers of hydroxycarboxylic acids located in the guide tube, is characterized in that...

20060018949 - Injectable biodegradable drug delivery system: Compositions for delivering a pharmaceutically active agent to the eye, and/or for treating an ophthalmic disorder, are based on a fumarate polymer, especially a poly(propylene fumarate) polymer....

20060018950 - Body ornamentation: A pattern is applied to human skin by applying a patch in the shape of the pattern to the skin. Sun tan lotion or sun tan oil is then applied to the patch and skin. The patch is unitary, flexible, and impervious to penetration by sun tan lotion and sun...

20060018953 - Eyelid margin wipes comprising chemical means for temperature adjustment: An eyelid margin wipe comprising chemical means for adjusting the temperature of the wipe relative to the ambient temperature. The wipe is particularly useful for treatment of disorders of the eyelid or eyelid margin such as meibomian gland dysfunction....

20060018952 - Molecular reactive chitosan finishing agent used for textile: A method for making a molecular chitosan finishing agent used for textile by adding an amino-alcohol derivative and an anionic surfactant into a chitosan acetic acid with different solubilities....

20060018951 - Ph-responsive film for intravaginal delivery of a beneficial agent: The present invention provides a delivery system for the intravaginal administration of prophylactic and therapeutic agents. In one embodiment, the invention provides a pH-responsive, biocompatible film for intravaginal administration of a beneficial agent, comprising a biocompatible, hydrophilic polymer that is positively charged at a first pH and in electronically neutral...

20060018954 - Magnesium-bearing wound-covering material: The invention concerns a biocompatible and bioabsorbable wound covering material. The object of the present invention is to improve wound care by a biocompatible, biodegradable wound covering material. In that respect body-specific defense and healing mechanisms are to be assisted and antimicrobial and antiproliferative effects are to be achieved. That...

20060018955 - Method for preparing medical dressings: Healing of wounds is promoted by covering and contacting the wound with a dressing that has been infused with a suspension of a starch hydrolysate containing ascorbic acid and other components, such as collagen and alpha-tocopherol acetate. In suspension, in the infused dressing or carrier the combinations avoid the tendency...

20060018956 - Dermal application system for aminolevulinic acid-derivatives: The invention relates to a dermal application system for aminolevulinic acid-derivatives, i.e. a pressure-sensitive matrix system containing a crystalline aminolevulinic acid derivative....

20060018957 - Pharmaceutical dosage forms including rasagiline: Provided are pharmaceutical dosage forms that include rasagiline formulated and fabricated so that release of rasagiline in the stomach is retarded or inhibited....

20060018958 - Coenzyme q10 formulation and process methodology for soft gel capsules manufacturing: A formulation of Coenzyme Q10, beta-carotenes, Vitamin E, and medium chain triglycerides in rice bran oil and an optional thickener, such as bee's wax, is provided in a soft gel capsule so that a maximum of the Coenzyme Q10 is absorbed by the human body. Generally, about 60 mg of...

20060018961 - Compression formed preparation and method for manufacturing same: A compression formed preparation that rapidly disintegrates in the mouth or in an aqueous solvent, which imparts an excellent feeling during administration, and maintains a suitable hardness required for handling such as distribution and the like, and a method for manufacturing the compression formed preparation. The present invention provides a...

20060018960 - Galenic formulations of organic compounds: The present invention relates to a solid oral dosage form comprising a therapeutically effective amount of aliskiren, or a pharmaceutically acceptable salt thereof, and wherein the active ingredient is present in an amount of more than 46% by weight based on the total weight of the oral dosage form....

20060018959 - Solid drug for oral use: e

20060018963 - Extended release venlafaxine besylate tablets: Venlafaxine besylate is formulated into an extended release tablet in high loading rates by use of a coating that contains ammonio methacrylate copolymer(s)....

20060018964 - Pharmaceutical formulation and process for its preparation: The present invention relates to a multiparticulate tablet with improved gastro-protection comprising at least a pharmaceutically active substance in the form of enteric coated particles, and a mixture of tableting excipients, wherein the said mixture of excipients comprising xylitol and/or maltitol, each in a directly compressible form, a disintegrating agent,...

20060018962 - Sustained release formulation of tramadol: This invention relates to sustained release oral dosage forms comprising tramadol or a salt thereof dispersed in a matrix, wherein said matrix comprises xanthan gum....

20060018965 - Solid oral dosage form containing seamless microcapsules: This invention relates to a solid oral dosage form containing one or more pharmaceutically active ingredients solubilised or suspended in a pharmaceutically acceptable solvent or liquid phase and encapsulated in seamless controlled release microcapsules. Accordingly the pharmaceutically acceptable solvent or liquid phase may range from aqueous phase, organic solvent(s), glycols,...

20060018966 - Antimicrobial mesoporous silica nanoparticles: Methods for preparing a series of mesoporous silicates, such as room-temperature ionic liquid (RTIL)-templated mesoporous silicate particles, with various particle morphologies are provided. Methods for preparing silicate particles with antimicrobial agents within the MSN pores is also provided. The particles can be used as controlled-release nanodevices to deliver antimicrobial agents....

20060018967 - Method for treating pipelines: A method for treating and sanitizing a pipeline, such as a drinking water line, wherein the pipeline is freed from internal deposits, if any, and then internally covered with a coating material. The coating material may be easily applied to the interior of the pipeline by the disclosed methods, and...

20060018968 - Use of polyethylene glycol based fluidized polymer suspension in functional systems: An aqueous based functional system contains a stable fluid polymer suspension (FPS) thickening agent of a polysaccharide, polyethylene glycol (PEG), and hydrated thickening silica. The functional systems may be formulations of personal care excluding oral care, household care, oil field servicing fluids, Civil Engineering servicing fluids, paper coatings, construction fluids,...

20060018972 - Aqueous sustained-release drug delivery system for highly water-soluble electrolytic drugs: The present invention relates to liquid sustained release suspension dosage forms comprising ionized forms of water-soluble drugs. In particular, the invention encompasses a liquid form controlled release drug composition comprising a dispersed phase comprising an ion-exchange matrix drug complex comprising a pharmaceutically acceptable ion-exchange matrix and a water-soluble electrolytic drug...

20060018970 - Enoximone formulations and their use in the treatment of cardiac hypertrophy and heart failure: The present invention provides formulations of the drug enoximone that include 40% to 80% non-ionic surfactant. Also provided a methods of treating heart failure and cardiac hypetrophy with these formulations....

20060018971 - Nucleic acid microspheres, production and delivery thereof: Nucleic acids are prepared by dissolving compounds containg them in a suitable solvent or solvent system and forming microshperes from the resulting solution. The microspheres are administered to an individual as protection from conditions where delivery of nuceic acids is useful, such as in treatment of autoimmune disease....

20060018969 - Pharmaceutical dose form and method of making the same: A method for producing a pharmaceutical dose form includes depositing a measured quantity of a first coating material on an external surface of the dose form in a patterned configuration. A measured quantity of a second coating material is deposited on the surface of the dose form in a patterned...

20060018974 - Calcium phosphate cements and methods for using the same: Methods and compositions for producing flowable compositions, e.g. pastes, that set into calcium phosphate products are provided. In the subject methods, dry reactants that include a calcium source and a phosphate source are combined with setting fluid to produce the flowable composition. A feature of the subject methods is that...

20060018973 - Composition for stimulating bone-formation and bone consolidation: The present invention relates to a composition for stimulating bone-formation and bone-consolidation, more particularly, to a composition for stimulating bone-formation and bone-consolidation by adding a material for stimulating bone-forming and bone-consolidation to the mixture of tripolyphosphate and water-soluble chitosan. The composition of the present invention can stimulate bone-formation and bone-consolidation...

20060018975 - Methods and compositions for weight management and mood enhancement: The present invention provides nutritional supplement compositions and processes for treatment using nutritional supplements that assist in weight management. One aspect of the invention comprises the inclusion in a single supplement constituent(s) that assist in reduction of a subject's cortisol level, thermogenic constituent(s), and constituent(s) that assist in stabilizing blood...

20060018976 - Nutritional supplement for osteoarthritis: The present invention relates to a method of treating osteoarthritis by administering a mineral composition in the form of a nutritional supplement, where the mineral composition may contain Smectite, Gypsum, Quartz, Feldspar, Jarosite, Kaolinite and/or Zeolite....

20060018977 - Beneficial agent delivery systems: An improved fragrance delivery system capable of providing controlled release of fragrance molecules in various consumer products is composed of a polymer having covalently bound fragrance moieties that are releasable in the form of fragrance molecules. Certain embodiments comprise globular polymer particles in which unbound fragrance molecules are occluded, absorbed...

20060018978 - Botanical compositions having hypoglycemic, hypolipidemic and antimicrobial activities for maintaining good health in normal person and diabetic patient: Botanical compositions are described having hypoglycemic, hypolipidemic and antimicrobial activity for maintaining good health in normal person and diabetic person comprising water extract of two medicinal plants, dried leaves of Malvastrum coromandelianum and/or dried stems of Coscinium fenestratum. The extracts are used separately or in combination of fixed amount or...

20060018980 - Hair restorer composition using oriental herbs: A hair restorer composition is produced by mixing 10 to 40 wt % of an Oriental herb extract of, 0.1 to 15 wt % of a viscosity control agent, 30 to 80 wt % of a surfactant, and 0.1 to 15 wt % of an oil. The Oriental herb extract...

20060018979 - Powder processing: A system is provided for pelletizing particulate raw matter having a first density, and thereafter subjecting the pellets to a milling process to obtain a powdered form of the particulate. During pelletizing steam can be added. The resulting powder is denser, or more granular or has better flow with less...

20060018981 - Sanitization process by using bacteriostatic or bactericidal products derived from vegetables: A sanitization process for obtaining a bacteriostatic or bactericidal action in an enclosed volume of space, comprising a stage of exposure of at least one bacteriostatic or bactericidal product obtained from at least one biologically grown vegetable in an amount ranging from 0.01% v/v to 3% v/v with respect to...

20060018982 - Topical application composition for preventing and treating pediculosis, method of elaboration and uses thereof: A composition of topical application for the prevention and treatment of pediculosis, elaboration method and uses of said composition. The composition comprises at least between 0.2 and 0.3% (w/v) of diallil tiosulphinate, wherein the diallil tiosulphinate is extracted from the garlic plant (Allium sativum sp). The method comprises the stages...

20060018983 - Composition containing green-yellow vegetables and light-colored vegetables: The present invention provides a composition comprising a green-yellow vegetable (e.g., broccoli, spinach, parsley, komatsuna (Brassica rapa L.), Japanese radish leaves) and a light-colored vegetable (e.g., lettuce, cabbage, celery), the composition having the following effects: (1) inhibiting the generation of blood lipid peroxide; (2) lowering blood TBARS levels or suppressing...

20060018984 - Intravaginal washing agent: An intravaginal washing agent by which the self-cleaning effect in the vagina of a patient suffering from a vaginal infection such as bacterial vaginosis, cervical chlamydiosis, trichomonal vaginitis or candidal vaginitis can be restored in the home, the invasion of bacteria, fungi, protozoa, etc. into the vagina can be prevented,...

20060018985 - Ant away: “Ant Away” is made from a petri dish that contains three (3) grams of dried bay leaves. When placed in dwellings, the object of this product will be to deter ants from dwellings. The aroma from the dried bay leaves will permeate through the ⅛″ holes drilled on the lid...

20060018986 - Extracts of decaffeinated coffee beans and orally administrable compositions comprised thereof for stimulating the sebaceous function of the skin: Orally administrable cosmetic/nutritional/pharmaceutical compositions suited for stimulating the sebaceous function of the skin, and/or for treating/preventing dry skin and/or skin aging, contain a thus effective amount of an extract of decaffeinated coffee beans, formulated into an orally administrable, physiologically acceptable medium therefor....

20060013767 - Virtual colonoscopy with radiolabeled phospholipid ether analogs: The present invention provides agents and methods for dual modality virtual colonoscopy that gives both anatomical and functional information using hybrid CT/PET scanning. In preferred embodiments, the present invention provides radiolabeled tumor-specific agents and methods for distinguishing benign polyps from malignant tumors. In further embodiments, the present invention provides compositions...

20060013768 - Injection of a radioactive dye for sentinel lymph node identification: A one-step procedure for sentinel lymph node identification and biopsy using a single compound, a radiolabeled, low molecular weight dye (e.g., 125I-labeled methylene blue). This radiolabled dye is mixed with an unlabeled, similar molecular weight dye (e.g., isosulfan or methylene blue). The mixture is injected at the time of surgery,...

20060013769 - Transdermal drug delivery formulations and method of determining optimal amounts of vasodilators therein: A method for determining and demonstrating the role of vasodilator chemical agents in the development and practice of transdermal drug delivery systems. Vasodilator chemicals applied topically dilate the blood vessels in the skin tissue, which have been shown to facilitate or inhibit systemic or skin tissue deposition of drug substances....

20060013770 - Method for screening for compounds as potential sedatives or anxiolytics: The present invention relates to a method for screening a chemical compound for its potential as a sedative or anxiolytica. The invention also relates to a drug development method and to the use of a compound as identified by the screening method for the treatment, prevention or alleviation of anxiety,...

20060013774 - Porphyrin compounds and their use in high-field mri: e

20060013772 - Method and device to recover diagnostic and therapeutic agents: The invention relates to a method and device for recovering therapeutic and diagnostic agents from the venous outflow of a tissue or organ. A method for recovering an agent includes inserting a catheter into a vascular outflow of a tissue or organ, occluding the flow of blood/fluid through the vascular...

20060013771 - Method of preparing gas-filled polymer matrix microparticles useful for echographic imaging: A method is provided to prepare gas-filled, porous microparticles having a polymer matrix interior which are useful as ultrasound echogenic contrast agents. An oil-in-water suspension is formed, both phases are frozen, then the aqueous and nonaqueous frozen phases are removed by sublimation. The resulting porous microparticles can receive a gas...

20060013773 - Biotype diets system: predicting food allergies by blood type: The invention is a diet-typing system for humans, including novel methods for diagnosis and treatment of food allergies and hypersensitivities. The diagnostic method correlates blood types (immunologically reactive antigens on RBC, skin and membranes) to four kinds of food allergies/hypersensitivities (IgE antibodies, IgG antibodies, T-cells, and Lectins). The results are...

20060013776 - Methods and compositions for treating benign gynecological disorders: An improvement in a method of treating benign gynecological disorders is described. In the method, treatment of a benign gynecological disorder with a composition comprised of a gonadotropin releasing hormone (GnRH) compound and an estrogenic compound, and optionally, an androgenic compound, is extended to premenopausal women who are not receiving...

20060013777 - Novel treatment for cough: The invention discloses the existence of cannabinoid receptors in the airways, which are functionally linked to inhibition of cough. Locally acting cannabinoid agents can be administered to the airways of a subject to ameliorate cough, without causing the psychoactive effects characteristic of systemically administered cannabinoids. In addition, locally or systemically...

20060013775 - Use of ppar activators for the treatment of pulmonary fibrosis: An activator of PPAR gamma is useful for the treatment of pulmonary fibrosis....

20060013778 - Method and composition for preventing tooth hypersensitivity when using passive bleaching agents: Dental bleaching compositions, for example in the form of liquids, gels, creams, pastes and ointments, comprising a peroxide releasing compound and from 1% to 35% by weight of a potassium-containing compound such as potassium nitrate, wherein the potassium nitrate is present in a safe and effective amount to prevent tooth...

20060013779 - Breath freshening and oral cleansing product with magnolia bark extract in combination with surface active agents: An oral composition for oral cleansing, breath freshening, and anti-microbial benefits includes Magnolia Bark Extract in combination with a surface active agent. The effectiveness of Magnolia Bark Extract in inhibiting biofilm formation in the oral cavity is increased by a synergistic combination of the Magnolia Bark Extract with a surface...

20060013780 - N,n'-dialkyl derivatives of polyhydroxyalkyl alkylenediamines:

20060013781 - Method and composition for producing enhanced fingernails: Method and compositions for strengthening, surface smoothing and thickening finger and toe nails by forming insoluble calcium phosphate materials within and on the surface of the keratin matrix of the nail. These insoluble calcium phosphate materials are developed by the application of solutions of calcium phosphate monobasic from various cosmetically...

20060013782 - Use of active extracts to improve the appearance of skin, lips, hair and/or nails: There is provided a composition having at least one of the following active extracts Butea frondosa, Naringi crenulata, Stenoloma chusana, or any combinations thereof. There is also provided a composition having at least one of the following additional extracts Azadirachta indica, Glycyrrhiza glabra linn., Morinda citrifolia, tomato glycolipid or any...

20060013783 - Fine o/w emulsion: The present invention relates to a composition containing lipophilic phase (A), an emulsifying system (B), and an aqueous phase (C) that is preferably suitable for topical use, in particular cosmetic and/or dermatological use, in the form of a fine oil-in-water emulsion that is rich in oil and can be obtained...

20060013788 - Cosmetic composition for caring for or making up keratin materials, comprising at least one polyester, and method of use thereof: The present disclosure relates to a cosmetic composition, for caring for or making up keratin materials, comprising, in a cosmetically acceptable medium, i) at least one polyester derived from the esterification, with a polycarboxylic acid, of an aliphatic hydroxycarboxylic acid ester comprising at least two hydroxyl groups and ii) at...

20060013787 - Oil-rich o/w emulsion: The present invention relates to a composition for topical application in the form of an oil-in-water emulsion, wherein it contains: a lipophilic phase (A) an emulsifying system (B) an aqueous phase (C), one or more fillers having an oil uptake greater than or equal to 75 ml/100 g, the emulsifying...

20060013786 - Skin preparation for external use: An external preparation for skin is provided which can be readily applied to the skin surface in a uniform manner, is excellent in effectiveness and storage stability, and has a pH of 2.0 or less. More specifically, the external preparation for skin of the present invention comprises one kind or...

20060013791 - Cosmetic composition comprising a defined silicone polymer and a film former: Cosmetic makeup and/or care compositions for application to the skin, lips and/or epidermal derivatives may exhibit improved staying power, satisfactory or improved gloss and improved comfort. The cosmetic compositions may include a film former and a silicon polymer....

20060013790 - Cosmetic composition comprising a defined silicone polymer and a gelling agent: The present invention relates primarily to a cosmetic makeup and/or care composition intended for application to the skin, lips and/or epidermal derivatives, comprising a particular silicone polymer, a liquid fatty phase and a gelling agent for said liquid fatty phase....

20060013789 - Cosmetic composition with improved staying power: Cosmetic makeup and/or care compositions for application to the skin, lips and/or epidermal derivatives, may include silicone polymers and hydrocarbon ester oils with low molecular weight....

20060013792 - Solid water-in-oil cosmetic emulsion: Disclosed is a solid water-in-oil emulsion comprising an aqueous phase emulsified with at least one emulsifying surfactant in a fatty phase comprising at least one ester oil and at least one wax, wherein the at least one ester oil is present in an amount greater than the at least one...

20060013793 - Solid water-in-oil cosmetic emulsion: Disclosed herein is a solid water-in-oil emulsion comprising an aqueous phase emulsified in a fatty phase comprising at least one ester oil and at least one wax, and at least one silicone surfactant comprising at least one polyhydroxylated chain or at least one alkyl dimethicone copolyol chosen from C8-C22 alkyl...

20060013794 - Cosmetic or pharmaceutical composition comprising peptides with the sequences arggly-ser: The invention relates to the use of at least one peptide, with the sequence (AA)n-Arg-Gly-Ser-(AA)n, where (AA) is any amino acid or a derivative thereof and n=0 to 3, as an active ingredient in or for the preparation of a cosmetic and/or dermatological and/or pharmaceutical preparation. The invention also relates...

20060013795 - Composition for hair treatment: The present invention pertains to a hair treatment composition that contains (a) a specific long-chain acylsulfonate type of anionic surfactant (such as an N-stearoyl-N-methyltaurine salt), (b) a higher alcohol, (c) an anionic polymer, and (d) a reducing agent or an oxidant, in which the combined amount of component (a) and...

20060013784 - Novel dimercaptoamides, compositions comprising them as reducing agents, and processes for permanently reshaping keratin fibers therewith: The present disclosure relates to specific dimercaptoamides, reducing compositions for permanently reshaping keratin fibers comprising the dimercaptoamides, for instance, human keratin fibers such as the hair; and processes for reshaping keratin fibers comprising the application of said reducing compositions. The present disclosure also relates to processes for preparing the dimercaptoamides....

20060013785 - Hairstyling gels with light protective action for skin and hair: The hairstyling agent in gel form contains a combination of at least one gel former, more than two percent by weight of at least one UV filter and at least one hair-fixing polymer. The hairstyling gel preferably is in optically clear form and can simultaneously have hair fixing action, light...

20060013796 - Hair and/or scalp treatment composition: Tulsi oil or a component compound thereof and a synthetic antimicrobial agent are capable of exhibiting a synergistic antimicrobial activity and are therefore useful in the manufacture of a composition for treating and/or preventing dandruff. A hair and/or scalp treatment composition comprises tulsi oil and a metal pyrithione, wherein the...

20060013797 - N-maleimidyl polymer derivatives: The invention is directed to multi-functional N-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly(alkylene glycol), the terminal carbon of the polymer backbone being directly bonded to the nitrogen atom of a N-maleimidyl moiety without a linking group therebetween. The...

20060013798 - Bis-quaternary ammonium salt corrosion inhibitors: wherein R7, R11 and R12 are independently selected from C1-C18 alkyl; R8, R9, R10 and R15 are independently selected from C8-C18 alkyl and C8-C18 alkenyl; R13 is C1-C4 alkyl; R14 is C2-C4 hydroxyalkyl; and R11 is selected from C2-C4 hydroxyalkyl, C2-C4 aminoalkyl and groups of formula —CH2)rNHC(O)R15 are effective inhibitors...

20060013799 - Multimeric vla-4 antagonists comprising polymer moieties: Disclosed are conjugates which bind VLA-4. Certain of these conjugates also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such conjugates are useful in the treatment of inflammatory diseases in a mammalian patient, e.g., human, such as asthma, Alzheimer's disease, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease,...

20060013800 - Stable immunogenic product comprising antigenic heterocomplexes: A stable immunogenic product for the induction of antibodies against one or more antigenic proteins in a subject, characterized in that it comprises proteinaceous immunogenic heterocomplexes which are formed by associations between (i) antigenic protein molecules and (ii) proteinaceous carrier molecules and in that less than 40% of the antigenic...

20060013801 - Prevention of and therapy for radiation toxicity of normal tissues using drugs which block il-1 activity: A method for the prevention of and therapy for radiation pneumonitis, dermatitis, soft tissue fibrosis and central nervous system toxicity in patients undergoing therapeutic radiation. In addition, the invention provides for pre-treatment of those responding to nuclear bio terrorism or other nuclear or radiological accidents. Thus, with the present invention,...

20060013802 - Techniques to treat neurological disorders by enhancing the presence of anti-inflammatory mediators: Methods and devices to enhance anti-inflammatory effects in the CNS to treat neurological, neurodegenerative, neuropsychiatric disorders, pain and brain injury are described. Anti-inflammatory enhancing agents that target IL-10 production and signal transduction pathways are discussed. Devices described include therapy delivery devices comprising a reservoir capable of housing an anti-inflammatory enhancing...

20060013803 - Modified dendritic cells: Infection of a dendritic cell with a lentivirus impairs the dendritic cell's ability to act as an antigen presenting cell that polarizes a naïve T cell to develop along the Th1 pathway. This impairment is restored by infecting dendritic cells with lentiviruses containing vectors encoding IL-7, IL-12, and siRNA targeting...

20060013805 - Transgenic circulating endothelial cells: A process is provided for expanding the population of endothelial cells obtained from peripheral blood which can be transformed with a vector comprising a DNA sequence encoding a preselected bioactive polypeptide. The resulting transgenic endothelial cells are useful to biocompatibilize implantable medical devices or can be used directly, as for...

20060013806 - Probiotics in primary prevention of atopic diseases: The present invention is in the field of prophylaxis of allergies, and relates specifically to primary prevention of atopic diseases by administering probiotic bacteria, beneficial microbes of the healthy gut flora, pre- and postnatally to children at high risk of atopic diseases....

20060013804 - Modulation of stem cell differentiation by modulation of caspase-3 activity: Methods of directing stem cell fate for therapeutic purposes through the deliberate manipulation of caspase-3 activity are provided. The use of modulators of caspase-3 activity to modulate stem cell differentiation is described including activators and/or effectors of caspase-3, which can be used to induce stem cell differentiation, and inhibitors of...

20060013807 - Rapidly disintegrating enzyme-containing solid oral dosage compositions: The present invention relates to rapidly disintegrating solid oral dosage forms having an effective amount of an enzyme and a superdisintegrant....

20060013808 - Treatment for asthma: A method for the treatment of asthma is disclosed. The method comprises administration of an antibody, polypeptide or other molecule recognizing VLA-4, a protein expressed on the surface of certain leukocytes such as eosinophils....

20060013810 - Humanized fcgammariib-specific antibodies and methods of use thereof: The present invention relates to humanized FcγRIIB antibodies, fragments, and variants thereof that bind human FcγRIIB with a greater affinity than said antibody binds FcγRIIA. The invention encompasses the use of the humanized antibodies of the invention for the treatment of any disease related to loss of balance of Fc...

20060013809 - Immunotoxin derived from a recombinant human autoantibody and method of using thereof: The invention is directed to an immunotoxin directed at fetal AchR, wherein the immunotoxin may comprises a human Fab fragment based on a human autoantibody or human combinatorial cDNA library and may be a pseudomonas exotoxin A-based single chain Fv IT (35-scFV-ETA). The invention is further directed to method of...

20060013811 - Methods of treating ige-associated disorders and compositions for use therein: The present invention provides methods of treating IgE-associated disorders and compositions for use therein. The methods are particularly useful in treatment of allergies and allergy-related disorders. The methods generally comprise administering an IgE inhibitor (such as anti-IgE antibody) and an antigen and/or immunostimulatory polynucleotide sequence (ISS). These combination methods offer...

20060013812 - Pharmaceutical composition comprising factor vii polypeptides and protein c inhibitors: The present invention relates to a composition comprising factor VII or a factor VII-related polypeptide and a protein C inhibitor, and the use thereof for treating bleeding episodes....

20060013813 - Proteins and nucleic acids encoding same: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research...

20060013814 - Methods for preventing pressure-induced apoptotic neural-cell death: Compositions and methods for protecting neuronal cells from pressure-induced apoptotic cell death which comprises administering to a subject in need of such treatment at least one compound which directly or indirectly inhibits the activity of an ion channel on neuronal cells and thereby inhibits the effect of pressure on the...

20060013815 - Human mob-5 (il-24) receptors and uses thereof: The present invention provides the receptors for Mob-5 (IL-24). One of the Mob-5 receptors comprises IL-22R1 and IL-20R2. Another Mob-5 receptor comprises IL-20R1 and IL-22R2. The invention also provides methods of inhibiting the Mob-5 receptor as well as methods of detecting cancer by detecting the presence of the Mob-5 receptor....

20060013816 - Method of treating psoriasis using human anti-tnf antibodies and fragments: Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-α (TNFα) and are useful in vivo diagnosis and therapy of a number of TNFα-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of...

20060013817 - Genetic products differentially expressed in tumors and use thereof: The invention relates to the identification of genetic products that are expressed in association with a tumor and the nucleic acid coding therefor. The invention relates to the therapy and diagnosis of diseases in which said genetic products that are expressed in association with a tumor are expressed in an...

20060013818 - Method of treating granuloma annulare or sarcoid: The invention provides a method of alleviating a granuloma annulare or a sarcoid disease by administering to a patient having the disease, a therapeutically effective amount of an LFA-1 antagonist....

20060013819 - Therapy of platinum-resistant cancer: The present invention concerns a method for treating platinum-resistant, ovarian cancer, primary peritoneal carcinoma or fallopian tube carcinoma with the combination of a HER2 antibody that effectively inhibits HER dimerization as well as gemcitabine....

20060013820 - Antigen delivery vectors and constructs: The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals....

20060013821 - Vaccine compositions and adjuvant: The immune response of an animal to a target immunogen may be enhanced by use of a novel adjuvant which includes low concentrations of killed cells of Mycobacterium avium subspecies avium in combination with mineral oil. The adjuvant may be used in vaccine compositions for the immunization of an animal...

20060013823 - Anticancer agent: The present application discloses a method of reducing tumor growth that includes contacting the tumor with a tumor growth reducing effective amount of a composition comprising LK8 or LK68 protein or a functionally equivalent amino acid variant thereof and a pharmaceutically acceptable carrier thereof to a subject having tumor....

20060013822 - Utilization of mhc class ii binding motifs in immunization to produce immune, serum, monoclonal antibodies and vaccines: This invention provides compositions and methods for raising humoral antibody responses. The compositions are peptides containing major histocompatibility Class 11 antigen binding motifs (ABM) either native or inserted into the peptide sequence. The ABM can be at the carboxy or amino terminus of the peptide and is shown to provide...

20060013824 - Rsv proteins, antibodies, compositions, methods and uses: The present invention relates to at least one novel RSV proteins, antibodies, including isolated nucleic acids that encode at least one RSV protein or antibody, RSV vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices....

20060013825 - Immune modulating compounds from fungi: The present invention relates to compositions comprising polypeptides and polysaccharides. The compositions are in general immune modulating. The invention also discloses methods of producing these compositions using filamentous fungi cultivated in liquid medium. The compositions are useful for example in the treatment of immune compromised conditions....

20060013828 - Immunizing fish against viral infection: The present invention provides the isolated causative agent of the disease affecting Cyprinus carpino and a method for its isolation. The invention further provides avirulent forms, e.g., live-attenuated form, inactivated form and genetically modified forms of the virus which may be used for vaccination of susceptible fish....

20060013827 - Method of diagnosing fiv: The present invention is directed to a method for diagnosing feline immunodeficiency virus (FIV) infection. The method involves the PCR amplification of a DNA sample obtained from a cat to be diagnosed. The PCR amplification utilizes a first gag-specific DNA primer derived from the gag gene region of an FIV...

20060013826 - Recombinant measles viruses expressing epitopes of antigens of rna viruses - use for the preparation of vaccine compositions: The invention relates to a recombinant measles virus expressing a heterologous amino acid sequence derived from an antigen of a determined RNA virus, said recombinant measles virus being capable of eliciting a humoral and/or cellular immune response against measles virus or against said RNA virus or against both measles virus...

20060013829 - Hyaluronan synthase gene and uses thereof: The present invention relates to a nucleic acid segment having a coding region segment encoding enzymatically active Streptococcus equisimilis hyaluronate synthase (seHAS), and to the use of this nucleic acid segment in the preparation of recombinant cells which produce hyaluronate synthase and its hyaluronic acid product. Hyaluronate is also known...

20060013830 - Vaccine: The invention relates to a method for treating or preventing (including immunising against) post-weaning multisystemic wasting syndrome (PMWS) and/or porcine dermatitis and nephropathy syndrome (PDNS) in a subject comprising administering an effective amount of a pharmaceutical composition or immune modulator composition comprising a whole cell of a bacterium from one...

20060013831 - Composition and method for enhancing immune response: A composition and method for enhancing immune response in a living organism is disclosed. In particular, the present disclosure provides an adjuvant peptide for use in raising an immune response to an antigen. The adjuvant peptide is selected from a group of peptides with an HIV-related sequence. Additionally, the adjuvant...

20060013832 - Methods for treating hiv infected subjects: Methods for inducing a population of T cells to proliferate by activating the population of T cells and stimulating an accessory molecule on the surface of the T cells with a ligand which binds the accessory molecule are described. T cell proliferation occurs in the absence of exogenous growth factors...

20060013835 - Controlled release bioactive agent delivery device: The invention provides a controlled release bioactive agent delivery device for treatment of an eye that includes a body member having a direction of extension, a longitudinal axis along the direction of extension, and a proximal end and a distal end, wherein at least a portion of the body member...

20060013836 - Parenteral formulation for epothilone analogs: A process for formulating certain epothilone analogs for parenteral administration is disclosed wherein the analog is dissolved in a mixture of at least 50% by volume tertiary-butanol in water, the mixture is lyophilized, the resulting lyophilized product is packaged in one vial with a sufficient amount of solvent comprising anhydrous...

20060013834 - Room temperature stable aqueous liquid pharmaceutical composition: A liquid pharmaceutical composition is contemplated that comprises a pharmaceutically effective amount of a drug dissolved or dispersed in an aqueous medium. The aqueous medium consists essentially of water, about 3% to about 10% w/v polyvinylpyrrolidone, about 60% to about 75% w/v of C3-C6 polyol that includes more than 55%...

20060013833 - Thermal stabilization of biocides in matrix compositions processed at elevated temperatures: A composition includes (a) a matrix, (b) a biocide, and (c) an antioxidant, in which said biocide exhibits thermal stability at matrix processing temperatures up to 250° C....

20060013843 - Cosmetic composition comprising a defined silicone polymer and a surfactant: The present invention relates to anhydrous cosmetic compositions of enhanced staying power, comprising, in a physiologically acceptable medium, at least one silicone polymer of defined general formula and a surfactant....

20060013838 - Cosmetic powder compositions having large particle size color travel effect pigments: A cosmetic composition preferably in powder form comprising pigments having a color travel effect, wherein said composition contains a sufficient amount of large particle size color travel pigments having a D50 particle size of at least 40 μm up to about 150 μm to retain the color travel effect upon...

20060013837 - Flavour compositions: A flavour composition, which can contain no or substantially no cinnamic aldehyde, comprises cinnamic alcohol and eugenol, the cinnamic alcohol and eugenol together comprising at least 3% by weight of the total weight of the composition, the weight ratio of cinnamic alcohol to eugenol being in the range 0.25:1 to...

20060013842 - Natural mixture of long-chain fatty alcohols and long-chain fatty acids, its obtension from animal and vegetable waxes and its nutraceutical uses: This invention is related to the obtention of a new natural mixture composed of long chain fatty alcohols and long chain fatty acids. This mixture has a relative composition of long chain fatty alcohols and long chain fatty acids that is highly reproducible batch to batch and it is extracted...

20060013839 - Shine-enhancing film formers: Shine-enhancing film formers are used to formulate cosmetic compositions in which shine is a desired property. Shine-enhancing film formers may be used alone for a high degree of shine or in combination with other film formers to modify the degree of shine. Using shine-enhancing film formers in cosmetics compositions often...

20060013841 - Skin treatment: A solution for the treatment of human feet. The solution includes an amount of each of the following components: 1) magnesium sulfate, 2) water, 3) methylparaben, 4) isopropyl alcohol, 5) methyl salicylate, and 6) malic acid. In combination, these components form an aqueous solution, which can be used as part...

20060013840 - Transparent topical cosmetic gel having colored fibers and method of using: There is provided a cosmetic gel. The gel has a multiplicity of colored fibers; one or more gellants; a film former different than the gellant if need for the gel to dry to a smooth film; and one or more liquid vehicles. The gel is substantially translucent, preferably transparent, and...

20060013844 - Facial cosmetic devices and systems: Several embodiments of a cosmetic device are disclosed. In general, the cosmetic device includes a thin, flexible substrate having two opposed sides, and an adhesive layer formed on one of the sides of the substrate. In some embodiments, a coloring layer is formed on the other side of the substrate....

20060013845 - Oxygenated personal care products: The present invention relates to a personal care composition containing water that has been treated with a combination of ozone and hydrogen peroxide. The personal care composition is further treated with liquid oxygen that is added to the composition prior to packaging. The personal care composition may be in the...

20060013846 - Agricultural or horticultural particulate composition comprising wettable granular agent: As a novel, agricultural or horticultural granular composition having a low foamability and comprising a granular wettable powder, that is, water-dispersible granules which can have an improved disintegrability in water, an improved dispersibility in water and an improved suspensibility in water, irrespective of the nature and the property of the...

20060013848 - Polymer with positive charges and the method for forming the same: A polymer with positive charges and a method for forming the same are disclosed. The polymer is made from N-substituted alkyl or aromatic 2-(dimethylamino)ethyl acrylate by polymerization. 2-(dimethylamino)-ethyl acrylate and initiators are dissolved in a first solvent and undergo a polymerization reaction. After polymerization, a halide is dissolved in a...

20060013847 - Thermal stabilization of ipbc biocide: A biocide, e.g. IPBC (3-iodo-2-propynl butylcarbamate), is stabilized against thermal degradation in matrix compositions which are processed at elevated temperatures, by blending the IPBC with a stabilizer additive, e.g. calcium stearate and/or a hindered phenol, alone or in combination therewith....

20060013850 - Electropolymerizable monomers and polymeric coatings on implantable devices prepared therefrom: Conductive surfaces of e.g., implantable devices, coated with electropolymerized polymers having active substances attached thereto are disclosed. Electropolymerizable monomers designed and used for obtaining such conductive surfaces and processes, devices and methods for attaching the electropolymerized polymers to conductive surfaces are also disclosed. The polymers, processes and devices presented herein...

20060013849 - Medical devices containing radiation resistant block copolymer: The present invention relates generally to radiation-resistant medical devices which contain polymer regions for release of therapeutic agents. The present invention also relates to radiation-resistant block copolymer materials for use in connection with insertable or implantable medical devices. The radiation-sterilized medical device comprise (a) a release region and (b) at...

20060013855 - Bioactive stents for type ii diabetics and methods for use thereof: The present invention is based on the discovery that a vascular stent or other implantable medical device can be coated with a biodegradable biocompatible polymer to which is attached a bioligand that specifically captures progenitors of endothelial cells (PECs) from the circulating blood to promote endogenous formation of healthy endothelium...

20060013854 - Medical devices containing copolymers with graft copolymer endblocks for drug delivery: The present invention provides a medical device comprising a release region and a therapeutic agent disposed within or beneath the release region, and the release region includes a copolymer comprising a low Tg block and at least one graft copolymer endblock having a main chain and a plurality of side...

20060013853 - Medical devices having conductive substrate and covalently bonded coating layer: The present invention provides a medical device comprising an electrically conductive substrate and a coating layer that covers at least a portion of the electrically conductive substrate, wherein the coating layer comprises a polymer that is made by a process that comprises (a) electrochemically linking a initiator to a surface...

20060013851 - Therapeutic polyanhydride compounds for drug delivery: Polyanhydrides which link low molecular weight drugs containing a carboxylic acid group and an amine, thiol, alcohol, or phenol group within their structure into polymeric drug delivery systems are provided. Also provided are methods of producing polymeric drug delivery systems via these polyanhydride linkers as well as methods of administering...

20060013852 - Use of organic compounds: The present invention relates to drug delivery systems, comprising an ARB or a RI, or at least two representatives selected from the group consisting of an ARB, an ACEI and a RI, or, in each case, a pharmaceutically acceptable salt thereof, for the prevention and treatment of proliferative diseases, particularly...

20060013857 - Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects: Component 2, a dispersing vehicle, may be esters unsubstituted and N-substituted pyrrolidones of C8-C18 monohydric alcohols with C2-C6 aliphatic monocarboxylic acids; C2-C18 monohydric alcohols with polycarboxylic acids; C8-C30 monohydric alcohols; tocopherol and esters thereof with C2-C10 aliphatic monocarboxylic acids or polycarboxylic acids; absorbable 10-14C hydrocarbons; free carboxylic acids such as...

20060013856 - New and advantageous hydrogel composition: New hydrogel, including a hydrogel containing cationic BSA is included in a vaccine to stimulate the immune system to increase the potency of the vaccine....

20060013859 - Drug delivery system using subconjunctival depot: The present invention provides a drug delivery system to a posterior segment wherein a pharmaceutical composition comprising a drug and a vehicle is administered subconjunctivally to form a depot out of the vehicle, and thereby the drug is gradually released from the depot to enable an effective concentration of the...

20060013858 - Fludrocortisone treatment for hearing loss: Methods and compositions for treating or stabilizing hearing loss due to cochlear disorders by administration of compositions that include fludrocortisone or a mimetic or analog thereof are disclosed....

20060013860 - Peptidyl prodrugs and linkers and stabilizers useful therefor: The present invention provides analogues of duocarmycins that are potent cytotoxins. Also provided are peptidyl and disulfide linkers that are cleaved in vivo. The linkers are of use in forming prodrugs and conjugates of the cytotoxins of the invention as well as other diagnostic and therapeutic moieties. The invention provides...

20060013861 - Functional foods comprising flavonoids and tocotrienols and methods thereof: Disclosed in certain embodiments is a functional food comprising an active agent combination comprising flavonoids and tocotrienols....

20060013863 - Hemostatic microfibrous constructs: Elastomeric fibrous constructs are formed from multicomponent, non-woven nano-/microfibers having a core and sheath configuration made primarily of an absorbable polymer and preferably a water-soluble one, respectively. Most preferably, the nano-/microfibers are produced by electrostatic spinning. Depending on clinical use of these constructs, suitable bioactive agents can be incorporated into...

20060013862 - Onychomycosis: a new process for cure: A new process and design, applicable to essentially all patients with onychomycosis, that represents a major ‘low-tech’ breakthrough in curing fungal nail infections that are a major source of irritation, morbidity, expense and mortality. The process begins with removal of the overlying infected nail (hands or feet). This achieves a...

20060013864 - Transmucosal pharmacuetical administration form: Planiform transmucosal pharmaceutical administration forms are disclosed, comprising a solid solution of the active ingredient in a phosphatidyl fraction, or a mixture of said phosphatidyl fraction with a copolymer of maleic acid and an alkyl vinyl ether. The administration forms are characterised by a low solubility in the buccal cavity,...

20060013867 - Medical devices and materials containing isobutylene copolymer: The present invention relates to medical devices which contain isobutylene copolymers. The present invention also relates to biocompatible copolymer materials for therapeutic agent delivery comprising a therapeutic-agent-loaded isobutylene copolymer. According to an aspect of the present invention, a medical device is provided, which includes: (a) a substrate and (b) at...

20060013866 - Transdermal drug delivery formulations with optimal amounts of vasodilators therein: Topical drug delivery formulations with optical amounts of vasodilator. Vasodilator chemicals applied topically dilate the blood vessels in the skin tissue, which have been shown to facilitate or inhibit systemic or skin tissue deposition of drug substances. The level of stimulation and/or inhibition has been found to be dependent on...

20060013865 - Transdermal patch for external use comprising fentanyl: A transdermal patch for external use having a backing layer and a pressure-sensitive adhesive layer formed on one surface of the backing layer, which contains polyisobutylene, a mineral oil and fentanyl employed as the active ingredient in the pressure-sensitive adhesive layer and in which the contents of polyisobutylene and fentanyl...

20060013868 - Controlled release preparation: A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the gastrointestinal tract, is provided by means such as capsulating a tablet, granule or fine granule wherein the release of active...

20060013869 - Electrospun amorphous pharmaceutical compositions: The present invention is directed to use of electrospinning, i.e. the process of making polymer nanofibers from either a solution or melt under electrical forces, to prepare stable, solid dispersions of amorphous drugs in polymer nanofibers....

20060013871 - Intimate coating of ibuprofen with poloxamers to enhance aqueous dissolution: This invention provides methods for enhancing the dissolution rate of Ibuprofen. More particularly, the invention provides a process for enhancing the solubility of Ibuprofen by intimately coating Ibuprofen particles with a Poloxamer. The invention also provides for a composition comprising a solid dosage form of Ibuprofen, wherein the surfaces of...

20060013872 - Pharmaceutical compositions comprising ibuprofen and domperidone: A stable pharmaceutical composition comprising a mixture of (i) an ibuprofen medicament; (ii) a domperidone medicamement; and (iii) a carrier material characterized in that the carrier material is substantially free of povidone and comprises at least one diluent combined with at least one release modifying agent....

20060013870 - Pharmaceutical compositions of hops resins: The present invention is drawn to a pharmaceutical composition comprising a dry free flowing powder. The powder can include various combinations of alpha acid, iso-alpha acids, and beta acids. The composition can further include a silica salt absorbent and/or an anti-oxidant. These compositions are preferably prepared by mixing hops extract...

20060013873 - Bioadhesive dosage form of steroids: Bioadhesive steroid nanoparticles are used to prepare a rapidly disintegrating solid oral dosage form of steroid. The bioadhesive steroid nanoparticles have a bioadhesive polymer surrounding the steroid nanoparticles and with an average diameter of less than 1000 nm. Hence, the solid oral dosage form, containing the bioadhesive steroid nanoparticles, a...

20060013875 - Combination immediate release controlled release levodopa/carbidopa dosage forms: The present invention relates to pharmaceutical dosage forms of a combination of carbidopa and levodopa comprising both immediate release and controlled release components for the treatment of ailments associated with depleted amounts of dopamine in a patient's brain tissue, which dosage forms display no food effect or at least substantially...

20060013874 - Extended release formulation of 3-amino-8-(1-piperazinyl)-2h-1-benzopyran-2-one: The present invention relates to an extended release formulation of 3-amino-8-(1-piperazinyl)-2H-1-benzopyran-2-one or a pharmaceutically acceptable salt thereof or a hydrate of said pharmaceutically acceptable salt thereof. The invention further relates to the preparation of these extended release formulations and their use in the prevention or treatment of disorders, especially pain...

20060013876 - Novel floating dosage form: Present invention relates to a novel pharmaceutical composition containing an active ingredient(s) which is retained in the stomach or upper part of gastrointestinal tract for controlled delivery of medicament for improved local treatment, and/or better absorption from upper parts of gastrointestinal tract for effective therapeutic results. Present invention also provides...

20060013877 - Hybrid of itraconazole, cyclosporine or carvedilol with a layered silicate and a process for preparing the same: The present invention provides the hybrids wherein itraconazole, cyclosporine or carvedilol are intercalated into the interlayers and/or absorbed onto the surfaces of layered silicates. The hybrids according to the present invention enable the maximization of bioavailability of drugs by dissolving the drugs from the layered silicates. Furthermore, the present invention...

20060013878 - Process for forming a gel containing an ingredient therein: A process for absorbing an ingredient into a gel item to form a gel has the steps of providing an ingredient and a liquid media, homogenizing the ingredient and the liquid media in a mixer to form a mixture, providing a gel item capable of absorbing the liquid media and...

20060013880 - Formulation stabilizer for proton pump inhibitors: The present invention provides a composition containing a benzimidazole derivative proton pump inhibitor and a polymeric base. The polymeric base is cholestyramine-OH, Eudragit E-PO, chitosan, or a mixture thereof. The composition stabilizes the benzimidazole derivative proton pump inhibitor in a humid environment so that degradation during storage....

20060013879 - Gel composition and methods: Methods and compositions for systemically or locally administering by implantation a beneficial agent to a subject are described, and include, for example, compositions having burst indices of 8 or less for systemic applications and systems releasing 10% or less of the total dose of beneficial agent in the first 24...

20060013881 - Hydrophilic antimicrobial composition for an air conditioner evaporator of a vehicle: The present invention relates to a hydrophilic antimicrobial coating composition for an air conditioner evaporator of a vehicle with improved durability. In one embodiment of the present invention, the antimicrobial composition comprises a hydrophilic organic polymer with molecular weight in the range of about 4,000 to 8,000, a smoothing agent,...

20060013883 - Poloxamer and poloxamine compositions for nucleic acid delivery: The invention features selected polymers such as poloxamer 188 (Pluronic® F68), poloxamer 237 (Pluronic® F87), poloxamer 401 (Pluronic® L121), poloxamer 338 (Pluronic® F108), Poloxamer 124 (Pluronic® L44), Poloxamer 184 (L-64), and poloxamines (Tetronics® 904, 908, 1107, and 90R4) that enhance expression from nucleic acids when administered into an organism, in...

20060013882 - Tri-block copolymers for nanosphere-based drug delivery: Biocompatible non-toxic triblock copolymers having an A-B-A structure wherein each A is a hydrophilic, biocompatible end block and the B middle block is a hydrophobic desaminotyrosyl tyrosine polycarbonate or polyarylate. The copolymers spontaneously self-assemble to form low critical aggregation concentration nanospheres having utility as delivery vehicles for hydrophobic biologically or...

20060013884 - Humidity-dependent antibacterial powdery composition, process for producing the same, humidity-dependent antibacterial food storing article and method of storing food: An object of the present invention is to provide a humidity-dependent antibacterial powdery composition of excellent applicability wherein a volatile oily antibacterial substance can be contained in high ratio; a process for producing the same; a humidity-dependent antibacterial food storing article; and a method of storing food. The humidity-dependent antibacterial...

20060013886 - Injectable microspheres: Injectable microspheres are obtained from double bond functionalized polyhydric alcohol ester by a method comprising dissolving the double bond functionalized esters in a hydrophobic organic solvent, forming an aqueous solution of stabilizer, forming an oil in water emulsion where the solution of stabilizer constitutes the continuous phase and the solution...

20060013885 - Water soluble chitosan nanoparticle for delivering an anticancer agent and preparing method thereof: The present invention relates to a water soluble chitosan nanoparticle (WSC-NP) for delivering an anticancer agent and a preparing method thereof, more precisely, a water soluble chitosan nanoparticle for delivering an anticancer agent which has function of targeting on a wanted area by introducing a functional group in the location...

20060013887 - Delayed release carnitine: A sustained release, orally administered pharmaceutical composition comprising carnitine and an acceptable pharmaceutical excipient is described for the treatment of carnitine deficiency and other carnitine responsive conditions. The sustained release formulation avoids the characteristic problems of gastrointestinal invitation, dumping in the urine and bacterial degradation attendant previously known oral formulations...

20060013888 - Solubilized coq-10: The present invention is directed to compositions and methods of delivery of CoQ-10 solubilized in monoterpenes. Use of monoterpenes as dissolving agents, greatly effects the ability to incorporate greater amounts of bioactive CoQ-10 in formulations, such as soft gel capsules....

20060013889 - Colostrum-based treatment for irritable bowel syndrome: A method for prophylactically treating irritable bowel syndrome in a mammal through the administration of a colostral composition like bovine colostrum is provided, although other forms of colostrum or other components exhibiting colostrum activity like lactoferrin, casein, or whey may be used. The effective amount of colostral composition to be...

20060013890 - Dairy-derived anticholesterol immunoglobulin to lower dietary cholesterol in humans: The present invention is related to naturally occurring immunoglobulin to cholesterol found in bovine milk that binds to cholesterol, LDL, IDL, and VLDL cholesterol. Milk and dairy-derived products containing immunoglobulin to cholesterol is internally administered to animals including humans. The composition is effective in lowering blood cholesterol and phospholipids by...

20060013891 - Quarternary compounds comprising propolis as the active substance: The present invention describes a quaternary composition consisting of propolis delivered in a hydrophilic carrier (cyclodextrin and cyclodextrin derivatives) and co ground with the aid of two compounds for the preparation thereof in the form of a finely divided powder. The composition exhibits advantageous dissolution characteristics in aqueous environments compared...

20060013892 - Administration of amino acid chelates for reduction in alcohol dependency: A method for reducing alcohol desire or dependency in a human can comprise the steps of administering an amino acid chelate or a combination of amino acid chelates to a human having alcohol dependency symptoms or an unwanted desire for alcohol. Naturally occurring amino acids may be used as ligands...

20060013893 - Bisphosphonates inorganic carriers: Intercalated hydrotalcite-bisphosphonate compositions have improved bioavailability, less irritation in the GI tract and a more constant controlled delivery rate of the active component. These hybrid organic drug—inorganic carrier are useful to build-up skeleton bone and to incorporate into a dentifrice to strengthen the hydroxyapatite mineral on teeth. Added advantages in...

20060013894 - Method for producing bone filler of calcium phosphate: A method for producing a calcium phosphate bone filler by preparing a mixed liquid comprising a calcium solution and a phosphoric acid solution in such a manner that a substrate of calcium phosphate exists in the mixed liquid, thereby precipitating calcium phosphate on the substrate to form a coating layer,...

20060013895 - Use of a composition and a cleaning tablet containing said composition for disinfecting purposes: whenever appropriate, a surface-active substance (tenside) or substance mixture, aromatic materials, adjuvants and binders for the disinfection of dental objects such as toothbrushes, dentures or razors and the like contaminated by retro or herpes viruses, pseudomonas aeruginosa and/or candida or parts of the body that have been attacked by retro...

20060013896 - Methods of treating acute pain using diclofenac: New pharmaceutical compositions for oral use containing diclofenac preferably together with alkali metal bicarbonates in amounts of from about 20 to about 80 by weight with respect to diclofenac are described. These compositions are entirely palatable and free from any unpleasant taste or other, side effects; in particular, these formulations...

20060013898 - Aromatherapy system: An aromatherapy system includes a fragrance impregnated card and a vial shaped and dimensioned for receiving the fragrance impregnated card. The vial includes a selectively removable closure limiting airflow within the vial for maintaining fragrance within the fragrance impregnated card. The fragrance impregnated card has a rolled configuration focusing fragrance...

20060013897 - Compositions for cancer therapy saponins or sapogenins: Compositions for cancer therapy comprising two or more saponins and/or sapogenins are provided. The compositions have enhanced anti-cancer activity when compared to each individual component alone. Also provided are pharmaceutical and non-pharmaceutical formulations comprising the compositions for use in the treatment of mammalian subjects having cancer, and pharmaceutical kits comprising...

20060013899 - Topical compositions for treatment of skin disorders and methods of use thereof: The present invention generally relates to topical compositions, and particularly to a topical ointment for treatment of skin disorders and methods of use thereof The present invention recognizes that treatment of certain skin disorders can be more efficient, safe, and rapid-acting with few or no side effects. The present invention...

20060013900 - Use of betel leaf extract to induce ifn-gamma production from human peripheral blood t cells and as a th1 type immunomodulator: This invention relates to use of betel leaf extract to induce IFNγ from human peripheral blood mononuclear cells and as a Th1 type immuno modulator, wherein the said method comprises the steps of, preparing water extract of betel leaf, preparation of human peripheral blood mononuclear cells, incubation of hPBMC with...

20060013901 - Compositions comprising flavonoids and tocotrienols and methods thereof: Disclosed in certain embodiments is a pharmaceutical formulation comprising a pharmaceutical ingredient comprising an active agent combination comprising flavonoids and tocotrienols in a ratio of about 75:25 to about 95:5 and at least one pharmaceutically acceptable excipient....

20060013902 - Pharmaceutical products for treating neoplastic disease and inflammation: Disclosed in certain embodiments is a pharmaceutical formulation and a functional food comprising a pharmaceutical ingredient comprising an active agent combination comprising flavonoids and tocotrienols in a ratio of about 75:25 to about 95:5 and at least one pharmaceutically acceptable excipient and methods to treat neoplastic diseases and inflammation....

20060013903 - Dietary supplements containing extracts of cinnamon and methods of using same to promote weight loss: A method for promoting weight loss and/or lowering blood glucose comprises an active material which may be cinnamon, an extract of cinnamon, or a derivative of a cinnamon extract. The active material may be utilized in combination with further active ingredients....

20060013904 - Treatment method comprising administering feverfew to oral mucosal tissues in solid or semi-solid form: An improved method for administering parthenolide and/or feverfew extract as a dietary supplement is provided, wherein an oral dosage composition comprising a dietary supplemental amount of parthenolide in a predetermined dosage amount of at least about 0.05 mg of parthenolide is orally administered to a patient. At least a portion...

20060013905 - Anti-inflammatory compositions for treating multiple sclerosis: Compositions with synergistic anti-inflammatory effects in inflammatory diseases resulting from activation and consequent degranulation of mast cells and followed by secretion of inflammatory biochemicals from the activated mast cells, the compositions containg one or more of a flavone or flavonoid glycoside a heavily sulfated, non-bovine proteoglycan, an unrefined olive kernel...

20060013906 - Anti-helicobacter activity of celery seed extract: The application discloses celery seeds or celery seed extract for treating Helicobacter pylori infections....

20060008415 - Stable liquid and lyophilized formulation of proteins: The present invention is directed to stable protein derivatives, e.g., antibodies, antibody fragments or peptides, with at least one free thiol group coupled to N-acetyl-L-cysteine, N-ethyl-maleimide, or cysteine and the methods of making such derivatives. In addition, stable liquid pharmaceutical formulations comprising such proteins or their derivatives and stable lyophilized...

20060008416 - High resolution metabolic brain imaging: This invention provides a method for determining whether a subject is afflicted with Alzheimer's disease by comparing the metabolic activity of the subject's hippocampal entorhinal cortex with that of a second region of the subject's brain. This invention further provides a method for determining whether a subject is afflicted with...

20060008417 - Lipophilic derivatives of chelate monoamides: Compounds useful for associating with nanoparticle or microparticle emulsions to obtain magnetic resonance images permit control of the relaxivity of the signal and readily associate with the particulate components. The compounds are conveniently prepared from achiral derivatives of chelating moieties....

20060008418 - Packaging and method for solid dose administration of an electronic identification chip and medicaments: A method and packaging for both vaccinating and identifying an animal by implanting a solid dose medicament and an identifying electronic microchip in an animal. The solid dose medicament, or plurality of such medicaments, are each, preferably color-coded to identify a particular active ingredient, then packaged in a pellet magazine...

20060008419 - Biomedical foams: The invention relates, generally, to porous absorbent materials which are suitable for packing antrums or other cavities of the human or animal body. More particularly, it relates to hydrophilic biodegradable foams, which may be used, e.g., in the form of a plug or tampon, for instance for controlling bleeding, wound...

20060008420 - Nasal spray formulation and method: A nasal spray formulation for use in female contraception or in the treatment of benign gynecological disorders is described. The nasal preparation is comprised of a GnRH compound and an estrogenic compound in the form of a water-soluble complex with a water-soluble cyclodextrin. The preparation effectively suppresses ovarian estrogen and...

20060008421 - Pharmaceutical combination: The present invention relates to a combination comprising (a) an adenosine A2a receptor agonist as defined herein and (b) an adrenergic β2 receptor agonist, for simultaneous, sequential or separate administration by the inhaled route in the treatment of an obstructive airways or other inflammatory disease....

20060008424 - Dental compositions with sensitivity relief: A one-component prescription fluoride treatment composition having both fluoride efficacy and sensitivity relief is disclosed. The composition includes at least one metal fluoride and a nerve desensitizing agent such as potassium nitrate. The invention further includes a composition having at least one metal fluoride less than about 1.15% by weight...

20060008423 - Dentifrice compositions and abrasive systems: A dentifrice composition comprising an abrasive system comprising a combination of a crystalline aluminosilicate having an average crystallite size below 1.0 μm and a water-soluble, orally acceptable calcium sequestering agent plus an orally acceptable carrier. The crystalline aluminosilicate may have an RDA of less than 120 and a calcium binding...

20060008422 - Dentifrice compositons and abrasive systems: A dentifrice composition comprising an abrasive system comprising at least one abrasive silica which may be selected from a first silica having a Radioactive Dental Abrasion (RDA) in the range 30 to 150 and a second silica an RDA in the range 100 to 300, and a crystalline aluminosilicate having...

20060008425 - Antiplaque oral composition containing enzymes and cyclodextrins: An antiplaque oral care composition having enhanced oral hygiene and organoleptic properties is provided. The composition contains an enzyme and a cyclodextrin. Papain and other proteolytic enzymes may be preferred. The resulting composition has more favorable organoleptic properties than a comparative composition containing only the enzyme....

20060008426 - Cosmetic and dermatological photoprotective formulations: Cosmetic or dermatological preparations which have a UVA balance of more than 15, and use thereof....

20060008428 - Method of promoting the penetration of a cosmetic active and composition therefore: The invention relates to a method of promoting the penetration of a cosmetic active, wherein a composition in the form of a water-in-oil emulsion is applied topically, said emulsion comprising a fatty phase with a polarity ba greater than or equal to 0.1 and comprising a mixture of at least...

20060008430 - Photostabilization of dibenzoylmethane uv-screening agents with arylalkyl benzoate compounds and photoprotective cosmetic compositions comprised thereof: e

20060008429 - Photostabilization of dibenzoylmethane uv-screening agents with arylalkyl benzoate/bis-resorcinyl triazine compounds and photoprotective compositions comprised thereof: Topically applicable, photostable compositions with respect to UV radiation contain at least one dibenzoylmethane UV-screening agent and at least one arylalkyl benzoate compound and at least one bis-resorcinyl triazine compound....

20060008427 - Sunscreen compositions with spf enhancer: The present invention provides a photo-protective composition that has a synergistic combination of at least one sunscreen agent and at least one carotenoid, which results in a composition with an increased SPF compared to a composition without the synergistic combination. Preferably, the composition also has at least one of the...

20060008431 - Copolymer functionalized with an iodine atom, compositions comprising the copolymer and treatment processes: The disclosure relates to copolymers functionalized with an iodine atom and including at least two different monomers. One of the at least two monomers is chosen from soluble monomers, and the other is chosen from insoluble monomers. The disclosure also relates to a cosmetic or dermatological composition comprising the copolymer...

20060008433 - Cosmetic emulsions containing liquid-crystal dyes: A emulsion-type cosmetic composition for caring for and/or making up the skin, mucous membranes and/or the integuments, includes at least one liquid continuous phase; and at least one liquid dispersed phase. The composition includes at least one volatile solvent; the dispersed liquid phase includes at least one dye with a...

20060008432 - Gilsonite derived pharmaceutical delivery compositions and methods: nail applications: Pharmaceutical formulations comprising Gilsonite oil for topical or transdermal application are disclosed. Also provided are methods for transdermal administration of a bioactive agent with enhanced penetration which comprise topical administration of a composition comprising transdermally effective amount of Gilsonite oil....

20060008434 - Deodorant body wash with lotion: Embodiments of the invention described herein include a formulation comprising: a deodorant, a structurant and an emulsion comprising a homogenized mixture of wax and alcohol components, at least one of which is a surfactant, wherein the formulation comprises a stable lamellar or spherulite phase....

20060008435 - Stabilized aqueous aluminum zirconium solutions: The present invention describes a method and compositions by which introducing PO4−3 ion at particular stage in the preparation of aluminum/zirconium solutions surprisingly results in significantly improved zirconium molecular weight stability....

20060008437 - Hair and skin care composition: The present invention provides cosmetic compositions that form a durable film or coating on surfaces such as hair or skin. The compositions of the invention comprise one or more anionic silicones and one or more high molecular weight esters, the combination of which provides a durable film. Methods for treatment...

20060008436 - Heterocyclic compound for stimulating or inducing the growth of the hair or eyelashes and/or slowing down their loss, composition comprising it and its uses: e

20060008438 - Multi-phased personal care composition: The present invention is a multi-phased personal care composition that contains at least two visually distinct phases. At least one of the visually distinct phases is a benefit phase that has a Flow Onset Temperature of at least about 97° F.; and wherein said visually distinct phases form a pattern;...

20060008441 - Cosmetic compositions comprising at least one polymethylsilsesquioxane film former: Compositions comprising at least one polymethylsilsesquioxane film former and at least one film former different from said at least one polymethylsilsesquioxane film former, wherein said at least one polymethylsilsesquioxane film former is present in an amount effective to provide at least one property chosen from long wear and transfer resistance....

20060008439 - Cosmetic compositions comprising at least one crosslinked copolymer, at least one cyclodextrin and at least one surfactant, and uses thereof: Disclosed herein are compositions comprising, in an aqueous medium, such as in a physiologically acceptably aqueous medium, at least one surfactant, at least one ingredient chosen from cyclodextrins and derivatives thereof, and at least one crosslinked copolymer comprising at least one methacrylic acid and at least one C1-C4 alkyl acrylate...

20060008440 - Cosmetic or dermatological preparations having a content of anti-freezing proteins and/or anti-freezing glycoproteins: A cosmetic or dermatological preparation that comprises one or more anti-freezing proteins and/or anti-freezing glycoproteins....

20060008442 - Metal ion modified high surface area materials for odor removal and control: This invention relates to modified high surface area materials, such as nanoparticles that are coated with metal ions, and articles treated with the modified high surface area materials. The modified nanoparticles have active sites that bind various gases and/or odorous compounds, thereby removing these compounds from a medium such as...

20060008443 - Ophthalmic compositions for lubricating eyes and methods for making and using same: Ophthalmic compositions include an ophthalmically acceptable carrier component, for example, an aqueous-based carrier, and a plurality of polyanionic component portions having different molecular weights. In one embodiment, the polyanionic component includes a first polyanionic component portion having a first molecular weight; and a second polyanionic component portion having a different...

20060008445 - Universal fishing bait based on fibrous collagen and the procedure for its preparation: The current invention involves a universal fishing bait fundamentally comprised of a matrix of fibrous collagen made up into any shape or design capable of attracting fish, that is 100% biodegradable and innocuous, that has physico-chemical properties that confer it with the capacity to accommodate liberate and diffuse attractant substances,...

20060008444 - Universal fishing bait based on filaments or strips of fibrous collagen: The current invention involves a universal fishing bait fundamentally comprised of a cord body of filaments or strips of fibrous collagen made up into any shape or design capable of attracting fish, that is 100% biodegradable and that furthermore has a good capacity to diffuse and liberate attractant substances. The...

20060008446 - Methods for treating pain: Methods of treating pain by delivery of anti-inflammatory cytokines, proinflammatory cytokine antagonists, and agents that act to reduce or prevent proinflammatory cytokine actions, to the nervous system are described. These agents can be delivered using gene therapy techniques. Alternatively, the agents can be delivered in protein compositions....

20060008447 - Stabilized interferon compositions: Stabilized pharmaceutical formulations comprising IFN-β and highly purified mannitol are provided. The highly purified mannitol stabilizes the compositions by reducing the formation of IFN-β adducts in comparison with IFN-β formulated with mannitol that has not been highly purified. Methods for increasing the stability of IFN-β or a variant thereof in...

20060008448 - Inhibition of li expression in mammalian cells: The present invention is directed toward compositions and methods involving the inhibition of Ii expression in cells for the purpose of altering antigen presentation pathways. More specifically, disclosed are compositions and methods which relate to MHC Class II molecule presentation of antigenic epitopes which, under normal circumstances, would not be...

20060008449 - Device and methods for treatment of necrotic tissue using stem cells: Devices and methods for precisely directing a dosage of therapeutic substance are disclosed. The devices include an elongated shaft member, a deployable needle associated with the elongated shaft member, an injection reservoir in fluid communication with the deployable needle; and means associated with the deployable needle for displacing the distal...

20060008451 - In vivo methods for effecting tissue specific differentiation of embryonic stem cells: Methods for producing derived differentiated cells from chimeric animals, fetuses and embryos derived from non-human chimeric embryos are provided. These non-human chimeric embryos are obtained by introduction of at least one transgenic ES or ES-like cell into a recipient non-human embryo, e.g., blastocyst stage embryo, wherein said ES or ES-like...

20060008452 - Mesenchymal precursor cell: A method of enriching mesenchymal precursor sells including the step of enriching for cells based on at least two markers. The markers may be either i) the presence of markers specific for mesenchymal precursor cells, ii) the absence of markers specific for differentiated mesenchymal cells, or iii) expression levels of...

20060008450 - Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure: The invention provides isolated stem cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple tissue types. Also provided are methods of isolation and culture, as well as therapeutic uses for the isolated cells in cardiac indications....

20060008453 - Methods and compositions for preventing and treating sensitive and dry skin: Compositions for preventing and/or treating sensitive and/or dry skin include at least an effective amount of at least one agent and at least an effective amount of at least one divalent inorganic cation, wherein the at least one agent includes at least one member selected from the group consisting of...

20060008455 - Methods and compositions for using aleveolar macrophage phospholipase a2: The present invention is directed to methods and compositions for improving pulmonary surfactant catabolism. More specifically, the specification describes methods and compositions for making and using a lysosomal phospholipase A2 in methods for the diagnosis, and treatment of disorders of phospholipid catabolism such as pulmonary alveolar proteinosis....

20060008454 - Use of a compound for enhancing the expression of membrane proteins on the cell surface: The present invention is directed to the use of a compound stimulating deubiquitinating activity in a cell for the manufacture of a medicament for enhancing the expression of integral membrane proteins on the cell surface. Especially, the invention is directed to the use of such compound for the manufacture of...

20060008456 - Natural humanized antibody: A reshaped human anti-HM1.24 antibody comprising: (A) L chains each comprising (1) a constant region of a human L chain, and (2) FRs of a human L chain, and CDRs of L chain of mouse anti-HM1.24 monoclonal antibody; and (B) H chains each comprising (2) a constant region of a...

20060008457 - Use of an active substance binding to cd28 for producing a pharmaceutical composition for the treatment of b-cll: The invention relates to the use of a superagonistic monoclonal antibody (mAb), which is specific for a naturally costimulatory receptor expressed on T cells, or a mimicry compound thereto, for producing a pharmaceutical composition for the treatment of diseases occurring with lacking costimulability of T cells, in particular of the...

20060008458 - Prevention of brain inflammation as a result of induced autoimmune response: A disease characterized by amyloid aggregation in a patient may be prevented or treated by causing antibodies against a peptide component of the amyloid deposit to come into contact with the aggregated or soluble amyloid. In order to decrease the risk of inflammation in such a method, the Fc receptors...

20060008459 - Combination therapy of respiratory diseases using antibodies: Therapeutically effective anti-microbial compositions, useful especially against respiratory diseases caused or mediated by viruses, bacteria, and other respiratory parasites are disclosed, wherein said compositions comprise at least one neutralizing antibody, including high affinity antibodies, and an additional anti-infectious agent, such as an antiviral agent, for example, ribavirin, amantadine, rimantadine, or...

20060008460 - Monoclonal antibody mr1 and uses thereof: The present invention relates to a counter-receptor, termed CD40CR, for the CD40 B-cell antigen, and to soluble ligands for this receptor, including fusion molecules comprising at least a portion of CD40 protein. It is based, at least in part, on the discovery that a soluble CD40/immunoglobulin fusion protein was able...

20060008461 - Microparticle-drug conjugates for biological targeting: This invention provides novel methods and reagents for specifically delivering biologically active compounds to phagocytic mammalian cells. The invention also relates to specific uptake of such biologically active compounds by phagocytic cells and delivery of such compounds to specific sites intracellularly. The invention specifically relates to methods of facilitating the...

20060008462 - Treatment of mammalian reaction of ige interactions: A method is disclosed for blocking or reducing physiological reaction in a mammal to the interaction of IgE antibodies present in said mammal upon contact with the corresponding antigen, by the administration to said mammal of a therapeutically effective amount of a neurotoxin (CnT) derived from Clostridia sp....

20060008463 - Tumor antigen peptides derived from cyclophilin b: Tumor antigen peptides derived from cyclophilins or derivatives thereof having the functionally equivalent properties; medicaments, prophylactics, or diagnostics for tumors comprising as an active ingredient such tumor antigen peptides or derivatives thereof, cyclophilins or partial polypeptides thereof, or genes encoding said cyclophilins or partial polypeptides thereof; in vitro use of...

20060008464 - Histone conjugates and uses thereof: A conjugate of a histone moiety covalently attached to a macromolecule-of-interest, in which the histone moiety is transportable through the cell membrane and importable into the cell nuclei, is disclosed. Further disclosed are chemical and recombinant methods of preparing such a conjugate, pharmaceutical compositions containing same and uses thereof for...

20060008465 - Novel methods for therapeutic vaccination: A method is disclosed for inducing cell-mediated immunity against cellular antigens. More specifically, the invention provides for a method for inducing cytotoxic T-lymphocyte immunity against weak antigens, notably self-proteins. The method entails that antigen presenting cells are induced to present at least one CTL epitope of the weak antigen and...

20060008466 - Methods for treating and preventing microbial infections: Methods for the treatment and prevention of microbial infection, such as infections caused by bacteria, viruses, fungi and parasites are disclosed, as are adjuvants for use with vaccines against such microbes. The methods use porcine β-defensins, such as porcine β-defensin-1 and are particularly useful for treating or preventing infections caused...

20060008467 - Human immunodeficiency virus vaccine: The present invention relates, in general, to human immunodeficiency virus (HIV) and, in particular, to an HLA-based HIV vaccine....

20060008468 - Combinations of tumor-associated antigens in diagnostics for various types of cancers: Disclosed herein are methods for matching a cancer condition with an appropriate immunotherapeutic agent and/or regimen. Also disclosed are methods for confirming diagnosis of a particular type of cancer. Embodiments of the invention disclosed herein are directed to the use of effective combinations of TuAAs to optimize the match between...

20060008469 - Infectious clone of human parvovirus b19 and methods: The invention relates to infectious clones of parvovirus B19, methods of cloning infectious B19 clones, and methods of cloning viral genomes that have secondary DNA structures that are unstable in bacterial cells. A B19 infectious clone and methods of producing B19 infectious clones are useful for producing infectious virus. Infectious...

20060008471 - Organ, tissue and cell-specific immuno-therapeutic for chronic viral infections and inflammatory, degenerative and proliferative diseases, in particular of the liver, and for cancer, based on a recombinant parapox virus: The present invention relates to the preparation and use of organ-specific, tissue-specific and/or cell-specific recombinant parapoxvirus ovis as a pathogen-specific and organ-specific, targeted immunotherapeutic agent for chronic viral infections and inflammatory, degenerative and proliferative diseases, in particular of the liver, and cancer....

20060008470 - Use of vaccinia virus deleted for the e3l gene as a vaccine vector: The present invention relates to vaccines having an increased level of safety comprising recombinant vaccinia viruses containing an inactivated E3L region. The invention also relates to methods for stimulating a protective immune response in an immunized host using the vaccines of the invention. The invention is based on the discovery...

20060008472 - Antigen delivery compositions and methods of use: The present invention provides antigen delivery compositions and methods of using same to prevent or to treat cancers and other infectious diseases. More particularly, the present invention provides a lipid-protamine-DNA (LPD) vaccine delivery system and methods of using such LPD vaccine delivery system for the prevention and treatment of cancer...

20060008473 - Influenza hemagglutinin and neuraminidase variants: Polypeptides, polynucleotides, methods, compositions, and vaccines comprising (avian pandemic) influenza hemagglutinin and neuraminidase variants are provided....

20060008474 - Polypeptides containing polymorphisms of the repeated regions of pertactin in bordetella pertussis, bordetella parapertussis, and bordetella bronchiseptica, their use in diagnostics, and in immunogenic compositions: Pertactin (PRN) is an outer membrane protein expressed by Bordetella pertussis, Bordetella parapertussis, and Bordetella bronchiseptica, which induces protective immunity to Bordetella infections. The immunodominant and immunoprotective epitopes of pertactin include two repeated regions, I and II. Comparison of these two repeated regions showed the pertactin of B. parapertussis is...

20060008475 - Shiga toxin b-subunit as a vector for tumor diagnosis and drug delivery to gb3 expressing tumors: The invention relates to new compounds for cancer therapy or diagnosis and to the use of a non-toxic B subunit of Shiga toxin mutant as a vector for diagnostic products or drugs in over-expressing Gb3 receptor cells, such compounds having the following formula: STxB-Z(n)-Cys-Y(m)-T wherein—STxB is the Shiga Toxin B...

20060008476 - Adjuvanted antigenic meningococcal compositions: A composition comprising a Neisserial antigen and a detoxified ADP-ribosylating toxin. These compositions have been found to be useful for mucosal immunisation, particularly nasal immunisation against Neisseria meningitidis....

20060008477 - Phenotype-determining virulence genes of pseudomonas aeruginosa for colonization and persistence in human beings, animals and plants, uses of said gene and associated proteins: Genes of the microorganism Pseudomonas aeruginosa are described which, when switched off, impair the virulence of said microorganism and even render it completely harmless. The genes all of which are known to be essential for the survivability of said microorganism in humans and animals are proposed as targets for the...

20060008478 - Immunoadjuvant: An immunoadjuvant which can efficiently exhibit potent adjuvant activity and avoid conditions undesirable for living bodies, and comprises precipitates formed by coacervation of (a) a soluble protein (provided that a soluble protein contained in tuberculin is excluded), and (b) a mucopolysaccharide, and further comprises (c) a soluble protein contained in...

20060008479 - Methods and compositions to generate immunity in humans against self tumor antigens by immunization with homologous foreign proteins: Methods and compositions to elicit or enhance immunity in humans against self tumor antigens are disclosed. Such immunity is generated by immunization with homologous foreign proteins. Self tumor antigens include protein expression products of overexpressed human oncogenes, such as human HER-2/neu protein, and organ-specific or tissue-specific differentiation antigens, such as...

20060008480 - Compositions for delivering highly water soluble drugs: The present invention provides compositions for delivering highly water-soluble drugs (such as vinca alkaloids) and methods of using such compositions....

20060008481 - Method and composition for treating hemorrhoids: A hemorrhoid-treating composition which includes a mixture of the antiseptic/bactericide/fungicide/anthelmintic gentian violet (methylrosaniline) and a lubricant such as petroleum jelly, also known as petrolatum or mineral jelly. In another embodiment, the composition is prepared as a suppository using a suitable suppository base. The composition imparts a soothing and healing effect...

20060008484 - Acne profile: The invention relates to an acne profile of an individual comprising an acne quality of life score which is determined by obtaining and analyzing acne quality of life information. The profile may also optionally contain an acne severity score which is determined by obtaining and analyzing acne severity information and/or...

20060008483 - Dispersions of lipids for use as therapeutic and cosmetic agents and intracellular delivery vehicles: In a dispersion of lipids in a dispersing medium, the said lipids comprising an amino-amidine compound A, the amidine function of the said compound A is titrated substantially in water by means of an acid HX, wherein X is an anion, in a manner such that the pH of the...

20060008487 - Method of skin care and/or treatment using thioredoxin: Methods for the prevention and treatment of skin damage arising from the exposure to UV radiation and other stressors capable of leading to the formation of free radicals, using the small dithiol protein thioredoxin in a dermatologically acceptable carrier that can be applied topically are disclosed. Some embodiments may include...

20060008488 - Microdermabrasion: The present invention relates to compositions and methods for removing an epidermal portion of the skin of a patient by microdermabrasion with a crystalline emulsion. The crystalline emulsion includes a mixture of coated crystals and a carrier. The coated crystals are formed by combining magnesium oxide, aluminum oxide or a...

20060008486 - Multifunctional compositions having combined insecticidal, mitacidal and fungicidal activity: Particular aspects provide novel insecticide/miticide/fungicide compositions, and methods for using same for safe, environmentally friendly control of insects, mites and fungal pests in, e.g., gardening and commercial growing. Preferably, the compositions comprise organic or pure ingredients. Particular embodiments comprise: a fatty acid soap base (e.g., saponified soap with retained glycerin;...

20060008482 - Oil phases for cosmetic agents: r

20060008489 - Oily makeup cosmetics: The present invention is to provide oily makeup cosmetics which comprises an oligo ester obtained from (a) an aliphatic acid or a hydroxy aliphatic acid having 8 to 30 carbon atoms (straight or branched, saturated or unsaturated), (b) a straight or branched dibasic acid having 12 to 36 carbon atoms,...

20060008485 - Packaged cosmetic compositions and related methods: A packaged powder-to-liquid-to-powder composition, a method for providing transfer resistant or long wearing cosmetic compositions, and a method for improving tone or laxity of skin....

20060008490 - Antimicrobial surfaces and methods for preparing antimicrobial surfaces: The present invention relates to biocidal articles. In an embodiment the biocidal article comprises a plurality of polymers having biocidally active groups. The polymers are attached to a surface and may have a polydispersity less than 3. The biocidally active groups may comprise at least one of a quaternary ammonium...

20060008494 - Complete inactivation of infectious proteins: The invention comprises a formulation and a method which uses the formulation. The formulation is comprised of an aqueous or alcohol solvent having therein (1) a detergent such as SDS; (2) a weak acid such as acetic acid; and (3) a chemical modification reagent such as hydrogen peroxide. The formulation...

20060008492 - Composition and method for delivering chemical agent to insects: Compositions and methods for delivering chemical or biological agents, nutrients or hormones to insects, especially chemical and biological agents that are effective in treating or preventing diseases or parasites in beneficial insects such as honeybees. The compositions generally comprise an oil, a protein/carbohydrate material, and an active ingredient. The composition...

20060008491 - Eremophilone and eremophilone derivatives for pest control: This invention relates generally to methods and compositions for controlling pests. More particularly, the invention relates to pest-controlling compositions, comprising as active ingredients, compounds of formula (I) where X, Y, R1, R2 and R3 are defined herein, and to the use of these compositions inter alia for preventing, eradicating, destroying,...

20060008495 - Pesticide for insect control: A method for the control of insects breeding on water surfaces and particularly mosquitoes, comprising blending in a high shear mixer water, the ester of a fatty acid of 10 to 25 carbon atoms and a low molecular weight alcohol, such as methanol or ethanol, an emulsifying agent and a...

20060008493 - Synergistic insecticidal composition containing chloronicotynyle and organosphosphorus compounds: A synergistic insecticidal composition is prepared by combining a Chloronicotynyle compound and an Organophosphorus (OP) compound. The preferred synergistically effective amount of the Chloronicotynyle compounds is an amount preferably ranging from 0.1 to 5% by weight of the composition. The preferred synergistically effective amount of the Organophosphorus (OP) compounds is...

20060008496 - Insulation paper facing containing an antimicotic or fungicide and methods of making and using the same: The invention relates to the papermaking art and, in particular, to the manufacture of insulation paper facing having improved reduction or inhibition in the growth of mold and/or fungus. This invention also relates to articles of manufacture made from such products such insulation, construction articles, buildings and the like....

20060008497 - Implantable apparatus having improved biocompatibility and process of making the same: An implantable apparatus has a plurality of fixed and detoxified protein layers formed in situ overlying at least one surface to improve biocompatibility. A process of making the implantable apparatus can include repeatedly exposing at least one surface of the implantable apparatus to a protein solution to form a multi-layered...

20060008498 - Nano-particle production: Larger particles (e.g., larger than 100 μm) of a material are processed to generate smaller particles having dimensions smaller than 200 nm. At least a portion of the processing is performed under a cryogenic condition and based on at least a physical property of the material under the cryogenic condition....

20060008500 - Implantable sensor with biocompatible coating for controlling or inhibiting tissue growth: All or a portion of a surface of an implantable sensor is covered with a biocompatible coating formed at least partially of a biomaterial matrix having properties that promote a substantially even growth of tissue cells over the surface of the coating. Additional materials, such as growth factors, agents that...

20060008501 - Intraluminal device with a coating containing a therapeutic agent: The invention relates to an intraluminal device, in particular an intraluminal prosthesis, shunt, catheter or local drug delivery device, provided with at least one coating containing a therapeutic agent comprised in a matrix which sticks to the intraluminal device, characterised in that said matrix is formed by a biocompatible oil...

20060008502 - Method and composition for bone growth: The present invention relates to novel chemical compositions and methods of treating and regenerating bone in a patient in need thereof. This invention presents a novel chemical composition of matter that stimulates osteoblast formation and inhibits osteoclastic and phagocytosis activity thereby resulting in a significant increase in bone formation....

20060008499 - Polyurethane based composition for filling or short-circuiting vascular cavities: The invention is directed to the use of a polyurethane for preparing a composition or a kit usable for filling or short-circuiting vascular cavities, where the polyurethane used can be dissolved in a solvent or a solvent mixture mingling with body fluids....

20060008503 - Therapeutic agent delivery device with controlled therapeutic agent release rates: The present invention relates to implantable medical devices for the localized delivery of therapeutic agents, such as drugs, to a patient. More particularly, the invention relates to a device having a gradient of water soluble therapeutic agents within a therapeutic agent layer and a mixing layer that allows for controlled...

20060008504 - Flexible bone composite: The present invention relates in general to implantable flexible bone composites, and method for preparing the same. The flexible bone composite includes at least one polymeric layer and at least one calcium-containing layer. The polymeric layer can be a polymeric layer including a synthetic polymer. The calcium-containing layer can include...

20060008505 - Product: A delivery system for a haemostatic material comprises a self adhesive strip of a bioadhesive, especially pectin and a glycerol plasticiser. The haemostatic material may be a microdispersed oxidised cellulose which is dispersed in the strip. The strip is applied to control localised bleeding from surface skin wounds such as...

20060008506 - Method for preparing therapeutic ophthalmic articles using compressed fluids: The present invention describes a method for the impregnation of a drug or a drug composition into ophthalmic articles, in order to prepare drug sustained release systems mainly for the treatment of glaucoma and other eye diseases. Ophthalmic articles can be for example contact lenses. The drug or drug composition...

20060008509 - Dietary supplement and method for the treatment and prevention of digestive tract ulcers in equines and other animals: A novel dietary supplement and nutritional aid and methods for the manufacture and administration of the same are disclosed for the efficacious treatment and/or prevention of digestive tract ulcers in horses and other animals. The dietary supplement of the present invention is effective in treating and/or preventing gastric ulcers, and...

20060008508 - Oral pharmaceutical compositions and methods of using the same: The present invention provides an edible composition for oral delivery of an active agent such as paclitaxel or a retinide. The composition comprises, in the form of a dry flowable powder: (a) an active agent such as a retinide; (b) lipid matrix composition; (c) optionally sweetener; (d) flour. Compositions of...

20060008507 - System for generating a bioactive dosage form: A system for generating a bioactive dosage form, including a first drop-on-demand fluid ejector fluidically coupled to a first reservoir that contains a first fluid having a first reactant. The first drop-on-demand fluid ejector is capable of ejecting a drop of the first fluid onto a pre-selected location of an...

20060008512 - Composition and methods for improved animal performance: Disclosed is a method for converting phenylalanyl to tyrosyl residues in casein by hydroxylation (OH) and for reacting diiodotyrosine with casein to get higher thyroxine yields the thyroactive iodination of casein. A method is disclosed for elevating blood thyroid hormone levels in avian species (especially poultry species such as chickens,...

20060008510 - Composition and methods for improved avian performance: A method is disclosed which is useful for elevating blood thyroid hormone levels in avian species (especially poultry species such as chickens, turkeys, ducks, quail, etc.) by implantation, injection, or supplementation of feed or water with thyroid hormones or thyroid-active substances (e.g., L-thyroxine, triiodothyronine, defatted and dessicated thyroid) to induce...

20060008511 - Probiotic products for pet applications: An exemplary embodiment providing one or more improvements includes feeding pets with probiotic microbes encapsulated in a mixture of xanthan gum and chitosan, or in gelatin, specifically Pediococcus acidilactici and Saccharomyces boulardii. Such encapsulation protects the viability of the probiotic microbes against unfavorable temperatures. Such feeding has the benefit of...

20060008515 - Anti-microbial chitosan composition for textile products: This disclosure provides an anti-microbial chitosan composition for use in textile products, methods of producing the anti-microbial chitosan composition, and techniques for incorporating the anti-microbial chitosan composition into products, and products comprising the anti-microbial chitosan composition....

20060008513 - Paper substrates and articles containing antimicrobial components as well as methods of making and using the same: The invention relates to the papermaking art and, in particular, to the manufacture of paper substrates, paper-containing articles such as file folders, having improved reduction or inhibition in the growth of microbes, mold and/or fungus....

20060008514 - Wipe and methods for improving skin health: The present invention relates to methods and products, such as wet wipes and absorbent articles, that are capable of imparting a health benefit when used in the intended fashion. More specifically, the products described herein comprise one or more botanical compounds, which are capable of selectively controlling the balance of...

20060008516 - Gilsonite derived pharmaceutical delivery compositions and methods: cosmetic applications: Pharmaceutical formulations comprising Gilsonite oil for topical or transdermal application are disclosed. Also provided are methods for transdermal administration of a bioactive agent with enhanced penetration which comprise topical administration of a composition comprising transdermally effective amount of Gilsonite oil....

20060008519 - Compositions and methods for stabilizing lipid based adjuvant formulations using glycolipids: The present invention relates to liposome formulations that are physically stable. In particular the present invention relates to steric stabilization of cationic liposomes by incorporating glycolipids into the liposomes. The stabilized liposomes can be used either as an adjuvant for antigenic components or as a drug delivery system. In particular...

20060008518 - Sphingomyelin analogues and a process for preparation thereof: e

20060008517 - Treatment of age-related memory impairment: Symptoms, including biochemical correlates, of age-related memory loss (ARML) in a mammal are beneficially affected by administering to the mammal small doses of bodies, such as liposomes, of a size resembling that of mammalian cells, the bodies having phosphate glycerol head groups presented exteriorly on their surfaces. Preferred are liposomes...

20060008520 - Delayed release formulations of 6-mercaptopurine: The present invention provides enterically coated formulations of 6-mercaptopurine that exhibit a delay in release of the 6-mercaptopurine such that substantial release of 6-mercaptopurine does not occur until after passage through the stomach. Optionally, the formulations also comprise a delay coating in addition to the enteric coating that provides an...

20060008522 - Pharmaceutical excipient having improved compressibility: A method of preparing an excipient composition includes forming an aqueous slurry containing a mixture of microcrystalline cellulose in the form of a wet cake and a surfactant, said surfactant being present in an amount from about 0.1% to about 0.5% by weight of the wet-cake microcrystalline cellulose; and drying...

20060008521 - Tablet excipient: This invention relates to a composition comprising physically modified, partially pregelatinized starch, which is useful as a multi-functional excipient for solid dosage forms, a method of making such composition, and solid dosage forms prepared using the composition. Such composition is characterized by a predominance of particles having both birefringent and...

20060008523 - Controlled release metformin compositions: A composition for treating patients having non-insulin-dependent diabetes mellitus (NIDDM) by administering a controlled release oral solid dosage form containing preferably a biguanide drug such as metformin, on a once-a-day basis. The dosage form provides a mean time to maximum plasma concentration (Tmax) of the drug which occurs at 5.5...

20060008524 - Controlled release metformin compositions: A composition for treating patients having non-insulin-dependent diabetes mellitus (NIDDM) by administering a controlled release oral solid dosage form containing preferably a biguanide drug such as metformin, on a once-a-day basis. The dosage form provides a mean time to maximum plasma concentration (Tmax) of the drug which occurs at 5.5...

20060008525 - Controlled release metformin compositions: A composition for treating patients having non-insulin-dependent diabetes mellitus (NIDM) by administering a controlled release oral solid dosage form containing preferably a biguanide drug such as metformin, on a once-a-day basis. The dosage form provides a mean time to maximum plasma concentration (Tmax) of the drug which occurs at 5.5...

20060008526 - Controlled release metformin compositions: A composition for treating patients having non-insulin-dependent diabetes mellitus (NIDDM) by administering a controlled release oral solid dosage form containing preferably a biguanide drug such as metformin, on a once-a-day basis. The dosage form provides a mean time to maximum plasma concentration (Tmax) of the drug which occurs at 5.5...

20060008527 - Controlled phase composition technology as an improved process for protection of drugs: The present invention relates to novel processes and compositions for protecting drugs, especially water soluble drugs in aqueous environments. More specifically, this process entails coating drugs with a controlled phase composition wax/lipid middle layer for controlling migration of the drug toward the composition's surface during preparation and a polymeric outer...

20060008528 - Fullerences to increase radiation resistance in polymer-based pellicles: A pellicle made of a polymer material contains fullerenes within the polymer material to reduce the damaging effects of radiation that is transmitted through the pellicle during an exposure operation. The fullerenes may comprise nanotubes and/or buckyballs. The buckyballs may also enclose molecules of a gas that further reduce the...

20060008530 - Tissue matrix system: The present application discloses matrix compositions to support the repair of tissue defects such as an osteochondral injury. A matrix described herein comprises a polyester polymer entangled with a polysaccharide polymer. Also disclosed are methods of preparing a matrix, and methods of using a matrix in the repair of tissue....

20060008529 - Use of additive sites to control nitric oxide release from nitric oxide donors contained within polymers: A method for increasing, prolonging, and/or controlling the release rates of nitric oxide (NO) from polymeric materials containing NO adducts. Such NO-containing polymeric materials may find use in devices such as blood contacting devices, and biocompatible devices utilizing the same. The method and device utilizes anionic site additives, acidic site...

20060008533 - Adsorbates containing active substances: A process is described for producing adsorbates suitable for human or animal nutrition and also cosmetics applications in which a component (A) to be adsorbed is applied to a carrier (C) using at least one stabilizer (B), the mean particle size of the carrier (C) being at least 80 μm,...

20060008532 - Complexes of protein crystals and ionic polymers: The present invention relates to complexes of protein crystals and ionic polymers and compositions comprising such complexes. The invention further provides methods for producing these complexes and compositions. The invention further provides methods for treatment of an individual having a disease requiring or ameliorated by sustained release of protein-based therapies....

20060008531 - Method for producing solid-lipid composite drug particles: A method of producing solid composite lipid/drug nanoparticles that includes the steps of: (1) dissolving a lipid and a drug in a suitable organic solvent to form a solution; (2) emulsifying the solution in a liquid to form an emulsion having a discontinuous phase of micelles comprising the organic solvent,...

20060008534 - Crystal liquid/crystal bioenergy device: My invention capitalizes on the fact that a crystal in resonance with a liquid such as water in a tube or closed container, acts to either pattern the liquid to a desired set of frequencies, or to act as an electromagnetic attractant to assimilate and clear adverse energies from the...

20060008535 - Anti tumor compositions and methods of use: An anti-cancer composition having biocompatible materials, which can selectively exploit chemical variations between normal cells and cancer cells to inhibit or prevent the proliferation of cancerous cells and methods of use....

20060008536 - Pharmaceutical compositions and methods of use: Compositions, kits including ingredients of the compositions, and methods useful in preventing and treating skin, mucosal tissue, and anorectal discomfort are presented, the compositions comprising an aromatic alcohol, an inorganic vasoconstrictor, an emulsifying agent, and a composition comprising one or more esters of fatty acids....

20060008537 - Method of treating acne: The invention features a composition including an anti-acne agent, an antimicrobial agent, and a lactate, and the use thereof in the treatment of acne....

20060008538 - Methods of treating the skin: The invention features a method of (i) reducing the appearance of pores or oil on the skin and (ii) evening skin tone or smoothing skin by applying to an area of skin in need of such treatment a composition including an anti-acne agent, an antimicrobial agent, and a lactate....

20060008539 - Coating-type antimicrobial composition, antimicrobial coating film, filter, and electric air-quality conditioning equipment: A coating-type antimicrobial composition contains at least a water extract of a plant body and a paint resin and/or a coating solvent. The plant body is, e.g., genus Eucalyptus, genus Kaemferia, genus Isodon, genus Scutellaria, genus Usnea, genus Pistacia, and genus Senecio....

20060008540 - Herbal compositions comprising portaluca: The present invention relates to herbal compositions and their use in suppressing appetite, promoting body weight loss, stimulating thermogenesis, and/or treating mood disorders, such as anxiety or anger. An herbal composition of the present invention can comprise Portulaca oleracea, and optionally, Green tea, Lotus leaf, and/or Ginseng....

20060008541 - Sodium channel agonist: The present application discloses a method of slowing inactivation of sodium current in a cell by contacting the cell with dimethyl lithospermate B....

20060008542 - Preparation containing a mixture of picrorrhiza and ginkgo for the relief of disease: Improved pharmaceutical compositions which include Ginkgo biloba and Picrorrhiza kurroa or extracts thereof, having a reduced amount of (or which do not include) components of natural Ginkgo biloba and natural Picrorrhiza kurroa which have effects which are detrimental to the effect or the pharmaceutical....

20060008544 - Methods for enhancing antioxidant enzyme activity and reducing c-reactive protein levels: An antioxidant-promoting composition that increases antioxidant defense potential in a subject is disclosed comprising Bacopa monniera extract; milk thistle extract, ashwagandha powder, green tea extract, Gotu kola powder, Ginko biloba leaf extract; Aloe vera powder; turmeric extract; and N-acetyl cysteine. The antioxidant-promoting composition of the invention safely induces cellular antioxidant...

20060008543 - Preparation of compositions to alleviate inflammation and oxidative stress in a mammal: An antioxidant-promoting composition that increases antioxidant defense potential in a subject is disclosed comprising Bacopa monniera extract; milk thistle extract, ashwagandha powder, green tea extract, Gotu kola powder, Ginko biloba leaf extract; Aloe vera powder; turmeric extract; and N-acetyl cysteine. The antioxidant-promoting composition of the invention safely induces cellular antioxidant...

20060008545 - Composition and method for treatment and prevention of pruritis: The present invention describes a composition for preventing pruritis or inflammation that includes field pussy-toes plant extract, and methods of using and manufacturing the same. The compositions of this invention have been found to be especially useful in preventing and treating lesions from poison ivy, chicken pox, and cold sores....

20060008546 - Organisms with enhanced histidine biosynthesis and their use in animal feeds: Disclosed are compositions and methods for supplementing ruminant feeds. The compositions include at least one ingredient that has an enhanced content of histidine. The ingredient may be derived from a non-animal source. One suitable animal feed composition includes (a) a histidine-enriched fermentation and/or biomass derived from fermentation of a microbe...

20060002851 - Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via isocyanate using azides and carbon-isotope monoxide: Methods and reagents for transition metal-promoted carbonylation via isocyanate using carbon-isotope labeled carbon monoxide are provided. The resultant carbon-isotope labeled compounds are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided....

20060002850 - Radiolabeled lymphatic staining agents and methods for making: A radiolabeled lymphatic staining agent is mixed on site with a much larger amount, on a weight basis, of a non-radiolabeled lymphatic staining agent to form an injectable radiolabeled lymphatic staining agent suitable for surgical use in humans. Preferably, the radiolabel is I-125, because it has a 60-day half-life which...

20060002853 - Stilbene derivatives and their use for binding and imaging amyloid plaques: This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method...

20060002852 - Targeted and high density drug loaded polymeric materials: Polymeric delivery devices have been developed which combine high loading/high density of molecules to be delivered with the option of targeting. As used herein, “high density” refers to microparticles having a high density of ligands or coupling agents, which is in the range of 1000-10,000,000, more preferably between 10,000 and...

20060002854 - Molecules that selectively home to vasculature of pre-malignant dysplastic lesions or malignancies: The present invention provides a conjugate that contains a therapeutic moiety linked to a homing peptide or peptidomimetic which selectively homes to vasculature of pre-malignant dysplastic skin and which includes the amino acid sequence SRPRR (SEQ ID NO: 1) or a conservative variant or peptidomimetic thereof. The present invention further...

20060002855 - Targeted combination immunotherapy of cancer and infectious diseases: The present invention is directed to methods for treating cancer wherein more than one therapeutic agent is used, with each of the therapeutic agents having different tumor-killing capabilities, and wherein the therapeutic agents are delivered to the tumor sites using combined targeting and pre-targeting methods. The methods of the present...

20060002856 - Methods for in vivo evaluation of physiological conditions and/or organ or system function including methods to evaluate cardiopulmonary disorders such as chronic heart failure using polarized 129xe: In certain embodiments, methods of the present invention obtain NMR spectroscopy signal data that corresponds to the behavior of the polarized 129Xe at a selected site(s) in selected environments in vivo. The gas exchange signal data can be used to evaluate: (a) the thickness of a barrier, such as a...

20060002858 - Concentrated x-ray contrast media can act as universal antigens and can inhibit or prevent allergic reactions: The present application is directed to the use of X-ray contrast media that act as universal antigens that are labeled herein as “pseudoantigens.” X-ray contrast media have the potential to exist in an aggregated state that is greater in increased concentrations. In this aggregated state, contrast media assume the role...

20060002857 - Non-isotopic detection of osteoplastic activity in vivo using modified bisphosphonates: The present invention is directed to a non-isotopic methods for the in vitro and in vivo detection of hydroxyapatite-positive cells and structures....

20060002860 - Abuse-proofed oral dosage form: The present invention relates to an abuse-proofed, oral dosage form with controlled opioid-release for once daily administration, characterised in that it comprises at least one opioid with potential for abuse (A), at least one synthetic or natural polymer (C), optionally delayed-release matrix auxiliary substances, physiologically acceptable auxiliary substances (B), optionally...

20060002859 - Process for production of an abuse-proofed solid dosage form: The present invention relates to a process for the production of an abuse-proofed solid dosage form containing at least one active ingredient with potential for abuse and a synthetic or natural polymer with a breaking strength of =500 N, characterised in that a corresponding mixture is processed by melt extrusion...

20060002863 - Aerosol suspension formulations containing tg 227 ea or tg 134 a as propellant: Disclosed are propellant gas formulations containing at least one suspended active substance which contains chemically bound water, water and the propellant TG 227 or TG 134 a....

20060002862 - High pressure spray-dry of bioactive materials: This invention provides compositions and methods providing, e.g., stable powder particles containing bioactive materials. The methods include, e.g., high pressure spraying of the bioactive materials in solution or suspension, with viscosity enhancing agents, organic solvents, and/or surfactants. Formulations are provided for spraying therapeutic bioactive materials into powder particles containing amino...

20060002864 - Milling process for the production of finely milled medicinal substances: The present invention is a method of milling materials to form a fine powder with a median particle size below 10 micrometer which is suitable for inhalation and which has substantially no amorphous content generated during milling. The method is particularly suitable for milling materials which are soft. The method...

20060002861 - Pharmaceutical compositions comprising 17alpha-furanylesters of 17beta-carbothiate androstanes with a muscarinic receptor antagonist: e

20060002865 - Stable baking soda/peroxide with calcium and phosphate whitening product: A dentifrice containing sodium bicarbonate, a peroxide generator, and remineralizing calcium and phosphate salts is provided within an anhydrous vehicle to maintain stability and palatability....

20060002868 - Cosmetic compositions: Use of cosmetic compositions comprising an □-hydroxyaldehyde self-tanning agent and a water-soluble vitamin B3 compound as a self-tanning composition are provided. The cosmetic compositions are useful for imparting a natural, even and durable tan to the skin when topically applied....

20060002871 - Cosmetic compositions and methods comprising rhodiola rosea: A cosmetic composition comprising a UV-protective amount of at least one rosavin, preferably present in an extract of Rhodiola rosea in a cosmetically acceptable vehicle, and methods of use thereof, including preventing or reducing the signs of photoaging....

20060002870 - Cosmetic compositions and methods containing a tanning agent and liposome encapsulated ursolic acid: A composition for topical application to the skin to provide tanning, comprising a liposome encapsulated ursolic acid, a tanning agent and a cosmetically acceptable carrier, and methods of use thereof....

20060002869 - Diesters containing two crylene or fluorene moieties, sunscreen compositions containing the same, and methods of photostabilizing a sunscreen compositions containing the same: Diesters that include one or more of a crylene and/or a fluorene moiety, and sunscreen compositions including a mixture of a photoactive compound and one or more of a diester that includes one or more of a crylene and/or a fluorene moiety are described herein. Also disclosed are methods for...

20060002866 - Method for protecting the skin from aging: The present invention relates to a cosmetic treatment method for improving and/or protecting the human skin, scalp and/or mucous membrane, characterized in that a preparation containing at least one substance which modulates proteoglycans, more particularly lumican and/or syndecan and/or versican and/or decorin and/or glypican and/or biglycan, is topically applied. Such...

20060002873 - Photostabilization of dibenzoylmethane uv-screening agents with arylalkyl benzoate compounds/amide-based oils and photoprotective compositions comprised thereof: Topically applicable, photostable compositions with respect to UV radiation contain at least one dibenzoylmethane UV-screening agent and at least one arylalkyl benzoate compound and at least one amide-based oil....

20060002872 - Solubilization of triazine uv-screening agents with arylalkyl benzoate compounds/amide-based oils and photoprotective compositions comprised thereof: Topcially applicable photoprotective compositions having improved sun protection factor, cosmetic properties and/or stability contain: (a) at least one 1,3,5-triazine UV-screening agent, (b) at least one mixture including: (i) at least one arylalkyl benzoate compound, and (ii) at least one oil containing in its structure at least one amide unit....

20060002867 - Uv barrier formulation for polyesters: The invention provides UV-barrier formulations which result in products which effectively resist the transmission of ultraviolet light therethrough. The invention also provides UV-barrier formulations which result in products with improved resistance to ultraviolet light. In particular, the invention provides UV barrier formulations for polyester resins that have improved resistance to...

20060002874 - Topical pharmaceutical composition to treat hyperpigmentation of the skin: Provided is a topical pharmaceutical composition for skin lightening, which is particularly useful in treating skin hyperpigmentation, together with methods for its use. The composition and methods involve the topical use of an active agent effective in the treatment of skin hyperpigmentation plus a permeation-enhancing base that, in one embodiment,...

20060002875 - Diffractive colorants for cosmetics: The invention relates to the use of diffractive colorants in cosmetics, to compositions comprising diffractive colorants, and to processes for the preparation of the compositions and to the use thereof....

20060002876 - Personal care compositions with improved hyposensitivity: The present invention provides personal care compositions comprising a carrier and a mixture of essential oil components having specific levels of eucalyptol, terpene materials and auxiliary fragrance materials. The compositions herein gentle to skin and have a fragrance and activity similar if the composition were made using the pure extracted...

20060002878 - Cosmetic article and related methods: The present invention provides a depilatory patch comprising a layer of depilatory composition carried by a substrate. The depilatory patch is arranged, in use, to be applied to the skin of a user and left for a prescribed time period before being removed. The depilatory composition acts to degrade or...

20060002879 - Methods of treating keratin based substrates: A composition for treating a keratin based substrate that includes a cosmetically acceptable medium containing a water-soluble interjacent complex. The water-soluble interjacent complex includes a first water-soluble polymer and a second water-soluble polymer formed by polymerizing one or more water-soluble monomers in the presence of the first water-soluble polymer. The...

20060002880 - Personal care compositions containing cationically modified starch and an anionic surfactant system: Personal care compositions comprise (a) from about 0.01 wt. % to about 10 wt. % of a water-soluble cationically modified starch polymer, wherein said water-soluble cationically modified starch polymer has a molecular weight from about 1,000 to about 200,000 and a charge density from about 0.7 meq/g to about 7...

20060002881 - Perfluorocarbon-soluble compounds: The invention describes syntheses and purifications of several perfluorocarbon-soluble compounds having a general formula RF-L-X or RF-L-X-L-RF, wherein RF is a perfluorocarbon group, X is a hydrophilic moiety, and L is an amide linkage of general structure —CO—NH—. The invention also provides microemulsions comprising a PFC forming an oil phase,...

20060002882 - Rinse-out cosmetic composition comprising elastomeric film-forming polymers, use thereof for conditioning keratin materials: e

20060002883 - Mild synthetic detergent toilet bar composition: A mild combination toilet bar composition is described that contains synthetic anionic surfactant(s) and soap(s) in a specified ratio and at least one low Krafft point co-surfactant. The toilet bar provides mild cleansing, and a draggy, clean-rinse feel during use....

20060002877 - Compositions and methods for permanently reshaping hair using elastomeric film-forming polymers: m

20060002884 - Anti-ageing skin cosmetic: The invention relates to a cosmetic based on various natural raw materials, which can be used to counter ageing processes of the human skin. The inventive cosmetic contains 0.1-5% by weight of an extract from a mixture of fig leaves and fruits, 0.1-3% by weight of an extract from pomegranate...

20060002885 - Use of combinations of active ingredients of one or more bioquinones and one or more isoflavones for improving the contours of the skin: A method of tightening and/or firming the skin and a method for the treatment and/or prophylaxis of cellulite, wherein the methods comprise applying to at least a part of the skin a cosmetic or dermatological O/W emulsion which comprises one or more bioquinones and one or more isoflavonoids....

20060002886 - Waste water treatment biocatalyst - cip: Disclosed is a composition of matter that features a liquid biocatalyst to stimulate biological activity. The composition is both environmentally and physically safe. The biological simulators in the inventive biocatalyst increase the metabolic and reproductive rates of most bacteria. Its introduction into a waste water treatment system non-selectively enhances aerobic...

20060002890 - Hydrogel formulations: A polymeric prodrug composition including a hydrogel, a biologically active moiety and a reversible prodrug linker. The prodrug linker covalently links the hydrogel and the biologically active moiety at a position and the hydrogel has a plurality of pores with openings on its surface. The diameter of the pores is...

20060002887 - Ionene oligomers and polymers: Polymerized ionene compounds are known to be effective antimicrobial substances. It has recently been appreciated that the molecular weight can affect the safety and efficacy of ionene compounds. In particular, it has been found that low molecular weight ionene oligomers (less than 50 repeat units) are less toxic than larger...

20060002889 - Polyionene polymers with hydrolyzable linkages: Ionene polymers are effective antipathogenic agents and can be used as a surface treatment or as a pharmaceutical agent. Ionene polymers typically are persistent in an environment because they degrade slowly, however, it is sometimes desirable to have a polymer that degrades over time. Ionene polymers that have one or...

20060002888 - Polyionenes for treating infections associated with cystic fibrosis: A method of using ionene polymers for the treatment or prevention of infections (e.g., pulmonary infections) in cystic fibrosis patients is provided. The method comprises administering to a mammal an effective amount of an ionene polymer to prophylactically or therapeutically treat infections associated with cystic fibrosis....

20060002891 - Cytomodulating conjugates of members of specific binding pairs: Novel conjugates are provided comprising a moiety capable of specifically binding to a target cell joined to a selective moiety for binding to an endogenous effector agent, capable of causing cell inactivation or cytotoxicity. Example of conjugates are a ligand for a surface membrane protein, e.g. IL-2 receptor, joined to...

20060002892 - Llt uses thereof in immune system modulation: Natural killer (NK) cells possess the inherent capacity to kill various tumor and virally infected cells and mediate the rejection of bone-marrow grafts in lethally irradiated animals. A large family of NK cell receptors belong to the C-type lectin super-family. Genes in the NK gene complex encode type II receptors...

20060002895 - Induction of apoptic or cytotoxic gene expression by adenoviral mediated gene codelivery: The present invention generally relates to viral vectors and their use as expression vectors for transforming human cells, both in vitro and in vivo. More particularly, the present invention relates to adenoviral vectors containing propapoptotic genes and their use in cancer therapy....

20060002894 - Method for introducing a biological molecule using a viral envelope and composition and system therefor: The object of the present invention is to provide a method of efficient delivery into a brain and central nervous system, and to provide a method of efficient delivery with a viral envelope. The present invention provides a system for introducing a biomolecule into a cell comprising A) a biomolecule;...

20060002896 - Method of generating recombinant mva: The present invention relates to MVA mutants, which can be used for the generation of recombinant MVA viruses, as well as host cells, which have been infected with these mutant MVA viruses. The present invention further relates to DNA-vector constructs, and a method for the generation of recombinant MVA by...

20060002893 - Targeted adenovirus vectors for delivery of heterologous genes: Modification of internal sites of the adenovirus fiber protein and hexon protein permit effective targeting of adenovirus vectors. Accessible sites to redirect adenovirus targeting were identified. The HVR5 loop of the hexon protein and the HI loop of the fiber protein (knob) were highly permissive for the insertion of foreign...

20060002897 - Vectors for tissue-specific replication: The invention generally relates to targeted gene therapy using recombinant vectors and particularly adenovirus vectors. The invention specifically relates to replication-conditional vectors and methods for using them. Such vectors are able to selectively replicate in a target tissue to provide a therapeutic benefit from the presence of the vector per...

20060002905 - Mutant forms of etxb and ctxb and their use as carriers: The present invention describes the use of a mutant form of EtxB or CtxB to deliver an agent to a target cell wherein the mutant has GM-1 binding activity; but wherein the mutant has a reduced immunogenic and immunomodulatory activity relative to the wild type form of EtxB or CtxB....

20060002904 - Receptor and related products and methods: The human receptor H4-1BB has been isolated, sequenced and disclosed herein. The cDNA of the human receptor H4-1BB is about 65% homologous to the mouse cDNA 4-1BB and was isolated by using probes derived from cDNA 4-1BB. A fusion protein for detecting cell membrane ligands to human receptor protein H4-1BB...

20060002906 - Tolerizing allografts of pluripotent stem cells: This disclosure provides a system for overcoming HLA mismatch between an allograft derived from stem cells, and a patient being treated for tissue regeneration. A state of specific immune tolerance is induced in the patient, by administering a population of tolerizing cells derived from the stem cells. This allows the...

20060002910 - Agent for the anti-adhesion of skin pathogenic flora: Bacterial agents for preparing compositions which are for cosmetic, pharmaceutical or veterinary use and which are intended to stabilize and/or regulate the cutaneous ecosystem of mammals. These bacterial agents are extracts of a bacterium, or a bacterium and are selected for their adhesion to skin cells and anti-adhesion to pathogens...

20060002908 - Bifidobacterium in the treatment of inflammatory disease: A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatroy activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may...

20060002907 - Method of improving immune function in mamals using lactobacillus reuteri strains: The invention herein is related to the use of Lactobacillus reuteri strains as immune enhancing agents, methods of improving immune-function in mammals using Lactobacillus reuteri strains in products containing cells of such strains and the products as such. These strains exhibit good toxin binding and neutralizing effect, and exhibit good...

20060002909 - Microorganism separated from kefir grains, a microorganism culture obtained by culturing said microorganism or microorganisms including it, and a product using such microorganisms or microorganism cultures: A single or mixed culture performed under conditions in which a new species of the Lactobacillaceae family having antioxidant properties and separated from Kefir grains can be cultured. An antioxidant having the obtained culture or bacteria as active principles is formulated and used as a raw material for or added...

20060002903 - Anti-inflammatory conformal barriers for cell transplantation: The invention comprises anti-inflammatory conformal barriers with controllable permeability properties that can be applied to living cells prior to transplant, and methods for coating living cells with conformal barriers. The coatings comprise polymer layers deposited on a cell surface by layer-by-layer polymer assembly, wherein each layer contains a positive and...

20060002901 - Composition containing eosinophil cationic protein: A therapeutic composition for a disease caused by a failure in the survival, proliferation and/or differentiation of a cell which contains eosinophil cationic protein and other components; and a medium composition for promoting the survival, proliferation and/or differentiation of a cell....

20060002899 - Generation of dendritic cells from cd34+precursors: The present invention relates to a method for inducing development of dendritic cells from CD34+ precursor cells. More particularly, the present invention relates to a method of differentiating CD34+ precursor cells into myeloid- and or lymphoid-dendritic cells. The present invention provides a protocol for the development of dendritic cells from...

20060002898 - Methods and compositions for correction of cardiac conduction disturbances: The invention provides methods for establishing electrical coupling between cardionyocytes and recombinant cells which have been genetically engineered to express a gap junction protein, eg., Connexin protein such as Connexin 43 (CX43) protein, n invention is based on the discovery that genetic modification of skeletal muscle cells to express a...

20060002900 - Retinal pigment epithelial cell cultures on amniotic membrane and transplantation: The present invention relates to a composition for implantation in the subretinal space of an eye, the composition including amniotic membrane, which may be cryopreserved human amniotic membrane, and a plurality of retinal pigment epithelial (RPE) cells or RPE equivalent cells present at the amniotic membrane. The amniotic membrane may...

20060002902 - System for providing implant compatibility with recipient: A system for providing or enhancing compatibility between an implant and a recipient. The system includes a recipient, typically a living biological organism, that further includes a target region; an implant having a first attraction means; and a plurality of cells. The cells are compatible with the target region and...

20060002911 - Association between a ppar ligand and an antioxidant agent and use thereof for treating obesity: The invention relates to a combination comprising one or more ligands of peroxisome proliferator activated receptors and an antioxidant agent, and to pharmaceutical compostions comprising the combination....

20060002912 - Methods for preventing post endoscopic retrograde cholangiopancreatography pancreatitis: The invention relates generally to methods for preventing post endoscopic retrograde cholangiopancreatography pancreatitis (ERCP). The method comprises administering a therapeutically effective amount of a pharmaceutical composition comprising secretin and a pharmaceutically acceptable carrier....

20060002913 - Use of histamine and related compounds to treat disorders affecting muscle function: Described herein are compositions and methods for treating and/or preventing disorders affecting skeletal muscular function that are caused by reactive oxygen species in mammals. More specifically, the disclosure relates to the treatment and/or prevention of disorders affecting skeletal muscular function through the administration of histamine and histamine-related compounds....

20060002914 - Methods and compositions for treating neuropathies: Methods of treating or preventing axonal degradation in neuropathic diseases in mammals are disclosed. The methods can comprise administering to the mammal an effective amount of an agent that acts by increasing sirtuin activity in diseased and/or injured neurons. The methods can also comprise administering to the mammal an effective...

20060002915 - Pharmaceutical composition comprising arginine deiminase for inhibiting angiogenesis: The present invention relates to a pharmaceutical composition for inhibiting angiogenesis which comprises arginine deiminase as an active ingredient, where the arginine deiminase, obtained from Mycoplasma arginini or prepared by a genetic recombination technique, may be conjugated to an activated polymer to lower its immunogenecity and increase its life time....

20060002916 - Cleavage of vegf and vegf receptor by wildtype and mutant mt-sp1: MT-SP1 mutein proteases with altered specificity for the target molecules they cleave can be used to treat human diseases, such as cancer. Cleaving VEGF or VEGFR at certain substrate sequences with wild-type and mutein MT-SP1 proteases can be used to treat pathologies associated with angiogenesis....

20060002917 - Effect of prolyl endopeptidase on digestive-resistant gliadin peptides in vivo: Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten....

20060002918 - Thrombin compositions: Compositions comprising thrombin and methods of preparing them are disclosed. The composition may be in the form of an aqueous solution at pH 5.7-7.4 consisiting essentially of 0.1 mg/mL to 5.0 mg/mL thrombin, 2% to 4% (w/v) sucrose, 3.5% to 5% (w/v) mannitol, 50 mM to 300 mM NaCl, 0-5...

20060002919 - 15625 receptor, a novel g-protein coupled receptor: The present invention relates to a newly identified receptor belonging to the superfamily of G-protein-coupled receptors. The invention also relates to polynucleotides encoding the receptor. The invention further relates to methods using the receptor polypeptides and polynucleotides as a target for diagnosis and treatment in receptor-mediated disorders. The invention further...

20060002920 - Pharmaceutical compositions directed to erb-b1 receptors: The invention relates to pharmaceutical compositions comprising different molecules, preferably monoclonal antibodies, each comprising epitopes that bind simultaneously to different sites within the same ErbB receptor domain, preferably the ErbB1 receptor domain. The preferred antibodies according to this invention are MAb 425 and MAb 225 each in its murine, chimeric...

20060002922 - Method for preventing or treating obesity by modulating the activities of the pentose phosphate patway: Method for preventing or treating overweight or obesity, the method comprising administering to a patient in need thereof an antagonist that inhibits gene expression or activity of an enzyme that is involved or related to the pentose phosphate pathway. Preferably, the enzyme is a transketolase, and the antagonist is an...

20060002921 - Optimized dosing with anti-cd4 antibodies for tolerance induction in primates: The present invention is based, at least in part, on the finding that tolerance can be induced by inhibition of CD4+ cells (and optionally CD8+ cells). Accordingly, the optimized dosing methods of the invention are useful in treating a primate, e.g., a human, by inhibiting CD4+ T cells to induce...

20060002926 - C-c chemokine receptor 3 proteins: The present invention relates to isolated and/or recombinant C—C Chemokine Receptor 3 (CKR-3, CCR3) proteins or polypeptides....

20060002924 - Conjugate of notch signalling pathway modulators and their use in medical treatment: Conjugates comprising a plurality of modulators of the Notch signalling pathway chemically bound to a support structure are described. The conjugates are useful for modulation of the Notch signalling pathway and treatment of associated conditions....

20060002923 - Recombinant anti-osteopontin antibody and use thereof: A recombinant antibody in which at least the constant regions in the heavy chain and the light chain have been converted into human-origin regions and which inhibits the binding of an integrin recognizing the RGD sequence to osteopontin or its fragment and inhibits the binding of an integrin recognizing the...

20060002925 - Soluble zcytor14, anti-zcytor14 antibodies and binding partners and methods of using in inflammation: The present invention relates to blocking, inhibiting, reduceing, antagonizing or neutralizing the activity of IL-17F, IL-17A, or both IL-17A and IL-17F polypeptide molecules. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. ZcytoR14 is a common receptor for IL-17A and IL-17F. The present invention includes...

20060002931 - Antibodies of angiogenesis inhibiting domains cd148: Anti-CD148 antibodies and antigen-binding regions thereof, as well as pharmaceutical compositions comprising such antibodies and antigen-binding regions, are described. Also described are methods of using such antibodies and antigen-binding regions to bind CD148 epitopes and activate CD148 function, such as inhibition of angiogenesis. Epitopes that can be used to activate...

20060002932 - Methods and compositions for enhancement of immunity by in vivo depletion of immunosuppressive cell activity: The present invention provides a method of enhancing an immune response in a subject, comprising administering to the subject a reagent that targets a cell having immunosuppressive activity, in an amount effective in reducing the immunosuppressive activity of the cell, thereby enhancing an immune response in the subject. Also provided...

20060002933 - Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies: The binding specificity of the murine OKT3 has been transferred into a human antibody framework in order to reduce its immunogenicity. “Humanized” anti-CD3 mAbs, such as gOKT3-5 and gOKT3-7, have been shown to retain, in vitro, all the properties of native OKT3, including T cell activation which has been correlated,...

20060002928 - Methods and molecules for modulating an immune response: A molecule capable of potentiating immune responses and modifying existing states of immune responsiveness is described. Also described are compositions containing the molecule, as well as methods for using the molecule and the compositions to enhance immune responses, to enhance DC function, to modify an existing state of immune responsiveness,...

20060002929 - Monoclonal antibodies: Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chains of monoclonal antibodies....

20060002930 - Treatment of disorders: The present invention concerns treatment of polychondritis or mononeuritis multiplex in a mammal with an effective amount of an antibody that binds to CD20, optionally also with another agent that treats such disorders in an effective amount....

20060002927 - Use of anti-cd1 antibodies for the modulation of immune responses: The invention provides methods for the administration of an anti-CD 1 antibody for the treatment or prevention of a variety of disorders, such as autoimmune disease, viral infection, bacterial infection, parasitic infection, infection by a eukaryotic pathogen, allergy, asthma, inflammatory condition, graft versus host disease, graft rejection, immunodeficiency disease, spontaneous...

20060002934 - Egf receptor antagonists in the treatment of gastric cancer: The present invention relates to a use of (an) EGF receptor antagonist(s)/inhibitor(s) for the preparation of a pharmaceutical composition for the prevention, amelioration or treatment of gastric carcinomas, preferably for the prevention, amelioration or treatment of diffuse gastric carcinomas. Furthermore, the invention provides for a method for treating or for...

20060002935 - Tumor necrosis factor receptor 1 antagonists and methods of use therefor: The invention provides methods for treating inflammatory diseases (e.g., chronic inflammatory diseases) comprising administering an antagonist of Tumor Necrosis Factor Receptor 1. The invention also provides antagonists of Tumor Necrosis Factor Receptor 1, such as ligands that contain an immunoglobulin single variable domain or domain antibody (dAb) monomer that binds...

20060002936 - Method of modulating platelet activation: The present invention relates to a method of treating a disease or condition mediated by platelet activation comprising supplying a therapeutically effective amount of an ERP5 inhibitor to a patient in need thereof, so as to reduce the effects of platelet activation in said patient....

20060002937 - Methods for treating conditions associated with masp-2 dependent complement activation: In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2...

20060002938 - Methods of detecting the inhibition of fibrocyte formation and methods and compositions for enhancing fibrocyte formation: The present invention relates to the ability of SAP to suppress the differentiation of monocytes into fibrocytes. It also relates to the ability of IL-4 and IL-3 to enhance the differentiation of monocytes into fibrocytes. Methods and compositions for binding SAP, decreasing SAP levels and suppressing SAP activity are provided....

20060002939 - Vaccines, methods, and antibodies specific for lipoteichoic acid of gram positive bacteria: The present invention encompasses monoclonal and chimeric antibodies that bind to lipoteichoic acid of Gram positive bacteria. The antibodies also bind to whole bacteria and enhance phagocytosis and killing of the bacteria in vitro and enhance protection from lethal infection in vivo. The mouse monoclonal antibody has been humanized and...

20060002942 - Calicheamicin conjugates: Anti-Lewis Y antibodies are described. Methods for preparing monomeric cytotoxic drug/carrier conjugates with a drug loading significantly higher than in previously reported procedures and with decreased aggregation and low conjugate fraction (LCF) are described. Cytotoxic drug derivative/antibody conjugates, compositions comprising the conjugates and uses of the conjugates are also described....

20060002943 - Compositions and methods for the treatment of tumor of hematopoietic origin: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same....

20060002941 - Compositions comprising immune response altering agents and methods of use: The present invention relates to immune response enhancing agents that alter an immune response generated against a heterologous target molecule. Compositions and methods of use of said immune response enhancing agents are also provided....

20060002940 - Method of immunotherapy: Disclosed are methods and compositions for the treatment of a variety of illnesses by mimicking the outer leaflet of an apotic cell to allow for the induction of macrophage phagocytosis to serve as a means of removing unwanted and diseased cells using phosphatidylserine/cell-surface recognition domain conjugate compositions. Also disclosed are...

20060002945 - Non-anaphylactogenic ige fusion proteins: The present invention provides compositions and methods for the use of antigenic peptides derived from the Fc portion of the epsilon heavy chain of IgE molecules from two unrelated species as vaccines for the treatment and prevention of IgE-mediated allergic disorders. In particular, the invention provides compositions for the treatment...

20060002944 - Treatment of complement-associated disorders: The present invention concerns a recently discovered macrophage specific receptor, CRIg, and its use in the treatment of complement-associated disorders....

20060002948 - Allergen from house-dust mites: The present invention relates to a novel allergen from house-dust mites, to polypeptides derived from said allergen and polynucleotides encoding the same. Furthermore, the invention provides antibodies directed against the allergen and to the use of the polypeptides, polynucleotides and/or antibodies in therapy and diagnosis of allergic disorders....

20060002947 - Ii-key/antigenic epitope hybrid peptide vaccines: Disclosed is an antigen presentation enhancing hybrid polypeptide which includes three elements. The first element is an N-terminal element consisting essentially of 4-16 residues of the mammalian Ii-Key peptide LRMKLPKPPKPVSKMR (SEQ ID NO: 1) and non-N-terminal deletion modifications thereof that retain antigen presentation enhancing activity. The second element is a...

20060002950 - Immunomodulatory protein derived from trypanosomes and uses thereof: The present invention relates to the field of immunomodulation. More particularly, the present invention relates to the identification and isolation of a polypeptide derived from Trypanosomes that can be used to modulate the immune response in mammals....

20060002946 - Targeted immunogens: The present invention provides reagents and methods for producing and utilizing targeted immunogens. In preferred embodiments, an immunogen is conjugated to an amino acid sequence that targets the immunogen to the MHC presentation pathway. Using the reagents and methods provided herein, immunization protocols may be enhanced resulting in increased immunity...

20060002949 - Transcutaneous immunization without heterologous adjuvant: Transcutaneous immunization can deliver antigen to the immune system through the stratum corneum without physical or chemical penetration to the dermis layer of the skin. This delivery system induces an antigen-specific immune response without the use of a heterologous adjuvant. Although perforation of intact skin is not required, superficial penetration...

20060002951 - Inhibition of the trnalys3-primed initiation of reverse transcription in hiv-1 by apobec3g: The present invention generally relates to the field of antiviral therapy. More specifically, the present invention relates to the inhibition of the tRNALys3-primed initiation of reverse transcription in viruses by APOBEC3G. The present invention further relates to a method of treating or preventing viral infections by inhibiting tRNALys3 annealing and/or...

20060002952 - Postweaning multisystemic wasting syndrome and porcine circovirus from pigs: The cloning of a novel PCVII viral genome is described as is expression of proteins derived from the PCVII genome. These proteins can be used in vaccine compositions for the prevention and treatment of PCVII infections, as well as in diagnostic methods for determining the presence of PCVII infections in...

20060002953 - Molecular differences between species of the m. tuberculosis complex: Specific genetic deletion are identified in mycobacteria isolates, including variations in the M. tuberculosis genome sequence between isolates, and numerous deletion present in BCG as compared to M. tb. These deletions are used as markers to distinguish between pathogenic and avirulent strains, and as a marker for particular M. tb...

20060002954 - Composition trapping radicals in organism: The object of the present invention is to provide a composition which is capable of going into erythrocyte or into cells, trapping not only oxygen radicals but also hydroxyl radicals, and preventing or improving various symptoms including hypertension, excessive sensitivity to cold, diabetes, Parkinson's disease, menstrual disorder, brain infarct, atopic...

20060002955 - Soil amendment compositions and methods for using the same: Soil amendment compositions and methods for using the same are provided. The subject compositions are aqueous compositions consisting essentially of a carbon-skeleton energy component, a predisposing agent and a vitamin-cofactor component. The subject compositions find use in a variety of soil amendment applications, including: the control of soil born pests...

20060002956 - Minicells as vaccines: The disclosed invention relates to immunogenic minicells cells (anucleated) and their use to induce an immune response from a subject....

20060002957 - Method and device for detecting feline immunodeficiency virus: A method and device for determining a feline immunodeficiency virus infection or vaccination in an animal. The method includes contacting a biological sample from a felid with various FIV polypeptides and determining the binding of antibodies in the sample to the polypeptides. The determination of whether an animal is infected...

20060002958 - Attenuation of metapneumovirus: The present invention relates to a vaccine against members of the genus metapneumovirus or RSV or a virus that comprises a significant genetic homology in the F protein to members of the genus metapneumovirus, whereby the vaccine is an attenuated live vaccine. In particular, the vaccine is directed against metapneumovirus...

20060002959 - Skin-sctive adjuvants for transcutaneous immuization: Transcutaneous immunization can deliver antigen to the immune system through the stratum corneum without physical or chemical penetration to the dermis layer of the skin. This delivery system induces an antigen-specific immune response. Use of skin-active adjuvants is preferred. Although perforation of intact skin is not required, superficial penetration or...

20060002960 - Gm1 binding deficient exotoxins for use as immunoadjuvants: Addition of a bacterial ADP-ribosylating exotoxin (bARE) to a formulation (e.g., immunogen or vaccine) or a system (e.g., patch or kit) for immunization enhances the immune response in a subject to one or more components of the formulation. Binding of the B subunit of a bARE to ganglioside GM1 of...

20060002961 - Vaccine: The present invention relates to the field of bacterial polysaccharide antigen vaccines. In particular, the present invention relates to vaccines comprising a pneumococcal polysaccharide antigen, typically a pneumococcal polysaccharide conjugate antigen, formulated with a protein antigen form Streptococcus pneumoniae, and optionally a Th1-inducing adjuvant....

20060002962 - Method of treating allergy and infection by eliciting an iga antibody response: The invention relates to a method of preventing or treating an allergy to or an infection by a mucosal antigenic agent in a subject comprising a) subjecting the subject to a priming treatment by means of parenteral or adjuvant-facilitated mucosal administration to activate the systemic immune system, and b) subjecting...

20060002963 - Use of emulsions for intra and periocular injections: A method for treating eye diseases by injecting intraocularly or periocularly a composition comprising an emulsion and optionally at least a pharmaceutical active ingredient....

20060002964 - Crosslinked cosmetic or pharmaceutical phospholipid-containing gels and emulsions based on ethylene oxide-containing or propylene oxide-containing emulsifiers: The invention is a process for making a cosmetic or pharmaceutical, phospholipid-containing crosslinked microemulsion gel or crosslinked oil-in-water emulsion. The process includes the use of at least one crosslinker that is added to at least one of the water phase and the oil phase of the emulsion, or the is...

20060002965 - Mixing device: The invention relates to a mixing device for mixing a pulverulent product, which is contained in a film sachet that is soluble in liquid, with said liquid and optionally at least one additional component. The aim of the invention is to accelerate the mixing of pulverulent products, which are packed...

20060002966 - Vaginal delivery of chemotherapeutic agents and inhibitors of membrane efflux systems for cancer therapy: Devices, methods, and compositions for cancer therapy by administration of chemotherapeutic agents and/or inhibitors of membrane efflux systems to the vagina for topical and systemic tumor targets....

20060002968 - Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders: Drug-delivery systems such as drug-delivery stents having an anti-proliferative agent such as everolimus and an anti-flammatory agent such as clobetasol are provided. Also disclosed are methods of treating a vascular impairment such as restenosis or vulnerable plaque....

20060002973 - Loading and release of water-insoluble drugs: A medical device, polymer composition, and method for delivering substantially water-insoluble drugs to tissue at desired locations within the body. At least a portion of the exterior surface of the medical device is provided with a polymer coating. Incorporated in the polymer coating is a solution of at least one...

20060002975 - Method and apparatus for reducing tissue damage after ischemic injury: A method and apparatus for the local delivery of therapeutic agents reduces myocardial tissue damage due to ischemia. A local delivery device is used for delivery of the therapeutic agents into a coronary artery which feeds the ischemic myocardial tissue. According to one example, an implantable medical device for delivering...

20060002970 - Method for coating a suture: The method of the present invention is for coating a suture thread. The suture thread is coated with a protein film, such as fibrinogen. An active enzyme inhibitor, such as a matrix metallo proteinase inhibitor, is immobilized to or associated with the film....

20060002969 - Methods for reducing the foreign body reaction: The present invention provides methods for reducing the foreign body reaction against a structure implanted within an animal body. The methods include the step of providing an amount of an MMP-9 antagonist at the site of the implanted structure that is sufficient to reduce the foreign body response against the...

20060002971 - Methods of treatment with drug loaded polymeric materials: Polymeric microparticles have been developed which encapsulate therapeutic compounds such as drugs, cellular materials or components, and antigens, and can have targeting ligands directly bound to the microparticle surface. Preferred applications include use in tissue engineering matrices, wound dressings, bone repair or regeneration materials, and other applications where the microparticles...

20060002974 - Polycationic peptide coatings and methods of coating implantable medical devices: Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed....

20060002972 - Reconstruction of urological structures with polymeric matrices: A method for repairing defects and reconstructing urothelial structures in vivo has been developed using a fibrous, open synthetic, biodegradable polymeric matrix which is configured to provide the desired corrective structure. The matrix is shaped to correct the defect, then implanted surgically to form a scaffolding for the patient's own...

20060002967 - Resorbable implant with lubricious coating: A device for surgical implantation that has a lubricious coating disposed on a polymeric matrix. The polymeric matrix establishes a biocompatible and at least partially bioresorbable scaffold adapted for ingrowth of native tissue. The lubricious coating is biocompatible and bioresorbable, and acts to lubricate the matrix and decrease friction on...

20060002976 - Absorbable putty-like implants and methods for their use for mechanical hemostasis of bone and for the treatment of osseous defects: Component 2, a dispersing vehicle, may be esters of C8-C18 monohydric alcohols with C2-C6 aliphatic monocarboxylic acids; C2-C18 monohydric alcohols with polycarboxylic acids; C8-C30 monohydric alcohols; tocopherol and esters thereof with C2-C10 aliphatic monocarboxylic acids or polycarboxylic acids; absorbable 10-14C hydrocarbons; free carboxylic acids such as oleic, linoleic, caprylic, capric,...

20060002977 - Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device: Drug-delivery systems such as drug-delivery stents having an anti-proliferative agent such as everolimus and an anti-flammatory agent such as clobetasol are provided. Also disclosed are methods of treating a vascular impairment such as restenosis or vulnerable plaque...

20060002978 - Biodegradable scaffolds and uses thereof: The invention is directed to scaffolds containing porous polymer material prepared by a process of gas foaming/particulate leaching and a wet granulation step prior to gas foaming and particulate leaching, particularly having a characteristic interconnected pore structure, as well as sustained release of protein, DNA or cells, and to methods...

20060002980 - High density fibrous polymers suitable for implant: This invention includes malleable, biodegradable, fibrous compositions for application to a tissue site in order to promote or facilitate new tissue growth. One aspect of this invention is a fibrous component that provides unique mechanical and physical properties. The invention may be created by providing a vessel containing a slurry,...

20060002979 - Multifunctional biodegradable composite and surgical implant comprising said composite: A multifunctional biodegradable composite has: a) bioabsorbable polymer matrix phase (M) b) bioabsorbable reinforcing element (R), and c) bioactive tissue/cell reaction modifying agent (TRMA) dispersed in said bioabsorbable matrix phase and selected from the group consisting of anti-inflammatory drugs and statins. Said biodegradable composite may be in a surgical implant...

20060002981 - Hyaluronic acid in the enhancement of lens regeneration: The present invention addresses the treatment of ocular conditions by the enhancement of lens regeneration. This is accomplished by the administration of a high viscosity composition including a hyaluronic acid compound. Excess high viscosity composition may be removed by focal laser photophacoablation. Additionally, a collagen product may be injected within...

20060002982 - Xanthan gum viscoelastic composition, method of use and package: The present invention is a novel viscoelastic composition that includes a suitable aqueous carrier and xanthan gum. The novel viscoelastic composition has rheological properties consistent with a good dispersive viscoelastic and improved damping ability over commercial dispersive viscoelastics....

20060002984 - Diet composition and method: A method of dieting includes providing a first food item; determining the caloric density and the number of calories of the first food item; providing a second food item; determining the caloric density and the number of calories of the second food item; adjusting amounts of the first and second...

20060002983 - Muscle building preparation: The present invention provides a muscle-building preparation for use during rehabilitation after injury or post-injury surgery, the preparation containing a composition comprising 42 to 55% by weight of protein, 12 to 20% by weight of fat, and 23 to 42% by weight of carbohydrate, on a dry weight basis of...

20060002985 - Compositions and methods for decreasing age-related deterioration in mental activities in companion animals: Feline diet compositions comprising a sulfur-containing antioxidant are disclosed. The composition improves at least one behavioral attribute indicative of preventing or decreasing age-related deterioration of the mental capacity. Also disclosed are methods of preventing such deterioration by feeding the diet composition to a feline....

20060002987 - Dissolvable film composition: A system, a kit and methods for delivering an effective amount of a labile active to the skin, comprising a composition comprising an effective amount of a labile active agent incorporated into a water-soluble polymeric film and an additive composition capable of dissolving the water-soluble polymeric film....

20060002986 - Pharmaceutical product: A pharmaceutical and pharmaceutical-like product is provided. The product provides an active agent that is not substantially absorbed into a carrier substrate. The active agent can be formed into a film on the surface of the carrier tablet or in a recess in the carrier tablet....

20060002989 - Formulations of sumatriptan for absorption across biological membranes, and methods of making and using the same: The present invention is directed to pharmaceutical compositions comprising sumatriptan succinate and sodium caprate for increased absorption of sumatriptan succinate across biological membranes. The invention is also directed to methods of making the pharmaceutical compositions and uses thereof....

20060002990 - Local nasal immunotherapy with allergen strip for allergic rhinitis: A method and strip for treating allergen-induced airway inflammation. The method includes applying a nasal or skin strip containing a mixture of an allergen and a pharmaceutically acceptable carrier to an individual having allergen-induced airway inflammation in a manner consistent with local nasal immunotherapy....

20060002988 - System and method for providing therapy to an individual: The present invention relates to a patch and method for providing therapy to an individual. The patch and method provide a user or therapist with the flexibility to apply a patch to highly contoured areas on the individual's body. In some embodiments, the patch includes a body that applies therapy...

20060002992 - Atomizable liposomes and their use for the pulmonary administration of active substances: The present invention discloses a method to prepare specific liposomal formulations for the pulmonary application of therapeutic substances. The liposomal components, DPPC and cholesterol at a molar ratio of 7:3 and 7:4, respectively, are combined with the non-toxic excipients, sphingomyelin, dimyristoylphophatidylcholine and/or polyethylene glycol, to prepare liposomes that are stabile...

20060002993 - Nucleic acid and corresponding protein entitled 161p2f10b useful in treatment and detection of cancer: A gene (designated 161P2F10B) and its encoded protein are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P2F10B gene or fragment thereof, or...

20060002991 - Ph-sensitive cationic lipids, and liposomes and nanocapsules containing the same: g

20060002995 - Pharmaceutical porous particles: The present invention relates to a pharmaceutical, preferably inhalable, porous, free flowing particle to be used in therapeutical application, optionally comprising a therapeutically active compound or substance, whereby the particle consists of one or more network forming compounds, which in diluted solutions self associates to large three dimensional structures having...

20060002994 - Responsive liposomes for ultrasonic drug delivery: This invention relates to biotechnology, more particularly, to an improved liposomal drug delivery system. Liposomes treated with or incorporating a surface active dopant, such as those containing polymers or oligomers of ethylene glycol as their hydrophilic “headgroup” component, have strongly increased permeabilizability when exposed to ultrasound. Permeabilizability was measured by...

20060002996 - Stable spray-dried protein formulations: Spray-dried particles having improved protein stability are produced by spray-drying a mixture including a protein, a phospholipid and an organic-aqueous co-solvent. Spray-dried particles which include at least 1 weight % phospholipid, having a tap density of less than 0.4 g/cm3 can be prepared. The particles can be delivered to the...

20060002997 - Nitrofurantoin controlled release dosage form: The present invention generally relates to controlled release dosage forms which provide immediate release and sustained release of nitrofurantoin, and processes for their preparation. The controlled release dosage form includes a sustained release portion and an immediate release portion. The sustained release portion includes nitrofurantoin and one or more pH...

20060002998 - Pharmaceutical dosage forms of biguanide-sulfonylurea combinations: The present invention relates to orally administered pharmaceutical compositions that include a combination of antidiabetic agents wherein one agent is present in an extended release form and the other agent is present in an immediate release form. For example, in one embodiment the dosage form includes an extended release layer...

20060003000 - Adhesively bonded dosage form: A solid pharmaceutical dosage form having a plurality of adhesively-joined subunits and also having one or more of the following: A. (i) a first inert tablet subunit and (ii) a second active subunit; B. (i) a first tablet subunit with a pharmacologically inactive layer in which said layer has a...

20060002999 - Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane: The present invention relates to an immediate release solid oral dosage form containing 1-aminocyclohexanes, preferably memantine or neramexane, and optionally a pharmaceutically acceptable coating, wherein the active ingredient exhibits dose proportionality and is released at a dissolution rate of more than about 80% within about the first 60 minutes following...

20060003001 - Chronotherapeutic compositions and methods of their use: e

20060003003 - Oral sustained release formulation of tedisamil with gastric retention properties: The present invention relates to a novel sustained release formulation with gastric retention properties comprising tedisamil or a pharmaceutically acceptable salt thereof and the use of this formulation in the prevention and treatment of atrial fibrillation, atrial flutter and cardiac ischemia....

20060003002 - Pharmaceutical compositions with synchronized solubilizer release: Pharmaceutical compositions with synchronized solubilizer release as well as various methods associated therewith, are disclosed and described. More specifically, the aqueous solubility of a drug is enhanced by synchronized release of a solubilizer....

20060003004 - Pulsatile release compositions of milnacipran: A once-a-day oral milnacipran pulsatile release composition has been developed that releases the drug in spaced apart “pulses”. The dosage forms are comprised of first, second and optional third dosage units, with each dosage unit having a different drug release profile. This dosage form provides in vivo drug plasma levels...

20060003005 - Tablet for pulsed delivery: A pharmaceutical tablet comprising an immediate release portion containing an active ingredient and a delayed release portion, wherein the delayed release portion comprises an enteric-coated layer and within the enteric-coated layer there is at least one member selected from the group consisting of enteric-coated microparticle dosage forms containing an active...

20060003006 - Controlled delivery system for bioactive substances: A biologically active composite solid shaped article comprising: (a) an outer layer, and (b) an inner core filling the said outer layer and comprising: at least a biologically active ingredient, and an excipient comprising at least a hydrophilic cellulose polymer and an amphiphilic material in the form of a blend...

20060003007 - Controlled extended drug release technology: A controlled extended drug release technology for the controlled extended release of hydrophobic or hydrophilic drugs or therapeutically active agents consisting of a homogeneous blend of one or more therapeutic agents, gas generators and surrounded by one or more layers of coat made of thermoplastic water insoluble cellulose derivatives, acrylic...

20060003008 - Polymeric devices for controlled release of active agents: Polymeric devices for controlled release of an active agent of interest are provided. The active agent is provided within a biodegradable polymer system to supply a polymeric device for controlled release of the active agent. The polymer system is a copolymer or a polymer blend comprising a hydrophobic component and...

20060003009 - Slow release protein polymers: The invention features articles for delivery of a biologically active substance, methods for making such articles, and methods for treating an animal using the articles....

20060003011 - Pharmaceutical compositions of drugs and neutralized acidic polymers: Pharmaceutical compositions comprised of low-solubility and/or acid-sensitive drugs and neutralized acidic polymers are disclosed....

20060003010 - Pharmaceutical formulations for the safe administration of drugs used in the treatment of drug addiction and processes for obtaining the same: The present invention provides safe pharmaceutical formulations for drugs used in the treatment of drug addiction, namely formulations which render the abusive administration of the drug contained in these formulations not feasible, together with processes for obtaining said formulations....

20060003013 - Grinding media and methods associated with the same: Grinding media are described herein. The grinding media can be used in milling processes to produce particle compositions. A wide variety of particle compositions may be produced with the grinding media which can be used in numerous applications....

20060003012 - Preparation of submicron solid particle suspensions by sonication of multiphase systems: The present invention provides a method for preparing submicron-sized particles. The method includes the steps of: (1) providing a multiphase system having an organic phase and an aqueous phase, the organic phase having a pharmaceutically effective compound therein; and (2) sonicating the system to evaporate a portion of the organic...

20060003014 - Safe delivery system for agriculturally active material: A safe delivery system of agriculturally active material is formed using an encapsulation process. A microencapsulated suspension of agriculturally active material includes an encapsulating agent formed from a graft copolymer of starch and at least one vinyl monomer....

20060003015 - Food composition effective for treatment of oral and throat diseases and method of producing the same: The present invention relates to a food composition effective for the treatment of oral and throat diseases and a method of producing the same, and more particularly to a food composition effective for the treatment of oral and throat diseases, made of crude drug materials exhibiting no side effects to...

20060003017 - Antioxidants in clusters of structured water: The invention relates to structured water and its antioxidant activity. In addition, the present invention relates to antioxidants incorporated within the cluster structure of either electropositive (S water) or electronegative (I water). The structured water, having the antioxidant within its cluster structure, has a stabilizing effect on the antioxidant. In...

20060003016 - Therapeutic method for endolymphatic hydrops associated diseases: A therapeutic method completely opposite to the known basic therapeutic policy including restriction of water and salt intake, which has been hitherto designated as the therapeutic method for Meniere's disease, and is a therapeutic method for endolymphatic hydrops associated diseases by performing water intake therapy for the patient with strongly...

20060003018 - Rare earth metal compositions for treating hyperphosphatemia and related methods: Rare earth metal compounds, particularly lanthanum, cerium, and yttrium, are formed as porous particles and are effective in binding metals, metal ions, and phosphate. A method of making the particles and a method of using the particles is disclosed. The particles may be used in the gastrointestinal tract or the...

20060003019 - Biologically inhibiting material a method of producing said material as well as the use of said material for inhibiting live cells: Biologically inhibiting material presenting a surface with separated areas of anode material and cathode material, where the distance between any point on the active surface and both the adjacent cathode material and the adjacent anode material does not exceed 200 μm, as well as a method of producing said material....

20060003020 - Anti-metastatic ability of mibefradil and gadolinium: The present invention relates to methods for inhibiting tumor cell metastasis in cancer comprising administering a composition comprising a T-type calcium channel inhibitor, such as mibefradil....

20060003021 - Method of treating breast cancer using a combination of vitamin d analogues and other agents: The invention provides therapeutic methods for inhibiting, ameliorating or alleviating the hyperproliferative cellular activity of diseases of the breast, e.g., breast cancer, which includes administering to a patient in need thereof an active vitamin D analogue and another anticancer agent. Cell differentiation is promoted, induced or enhanced without causing to...

20060003022 - Methods and compositions for controlling microorganism populations in the digestive system of animals: The invention is related to methods and compositions for controlling microorganism populations in the digestive system of an animal. In an embodiment, the invention is a method for reducing protozoa populations in the digestive system of an animal including administering an effective amount of a saponin containing composition to the...

20060003023 - Microbicidal composition: A microbicidal composition containing: (a) a stabilized hypochlorite and bromide composition; and (b) at least one microbicide selected from among 2-methyl-4-isothiazolin-3-one, 5-choloro-2-methyl-4-isothiazolin-3-one, 4,5-dichloro-2-N-octyl-4-isothiazolin-3-one, 1,2-benzisothiazolin-3-one, 3-bromo-1-chloro-5,5-dimethylhydantoin, poly(hexamethylenebiguanide hydrochloride), alkyl-dimethyl-benzylammonium chloride, pentane-1,5-dial (glutaraldehyde), 5-bromo-2-nitro-1,3-propane-diol and 2,2-dibromo-3-nitrilopropionamide....

20060003024 - Iodizing agent and process for preparation thereof: A method for preparation of iodizing agent for the use in the formulation of iodised salt that offers excellent stability of iodine in iodised salt is developed and the unrefined salt iodised with this compound was tested for its stability in presence of moisture, temperature and metal salts at higher...

20060003025 - Aqueous ionic solutions and their uses in particular in ophthalmology: The invention concerns the use for treating and cleaning the eye and its appendages of aqueous ionic solutions obtained from sea water whereof the ionic composition is qualitatively that of sea water and quantitatively such that their pH ranges between 4 and 9, preferably between 7 and 8 and their...

20060003026 - Chinese preparation for treating enteritis ulcer colitis and preparation method thereof: This invention provides a preparation of traditional Chinese medicinal materials for the treatment of ulcerative colitis and the processed method thereof. The preparation of present invention is prepared from 1-10 wt % of Sanguis Draxonis, 15-40 wt % of Radix Paeoniae Rubra, 1-20 wt % of Indigo Naturalis, 1-10 wt...

20060003027 - Composition and method for reducing side effects of indole-3-carbinol and derivatives: A method is provided for reducing side effects while treating a mammal using indole-3-carbinol, which method includes the steps of administering an effective amount of indole-3-carbinol along with side effect-reducing amounts of a side-effect reducing component. A composition is also provided, as are various combinations of side effect-reducing agents....

20060003028 - Stable oxidizing bromine composition, method of manufacture and use thereof for biofouling control: A stable oxidizing bromine biocidal composition comprising at least one stable oxidizing bromine compound that is prepared from at least one oxidizing chemical reagent, at least one bromide source and at least one bromine or halogen stabilizer, wherein the molar ratio of bromide source to stable oxidizing bromine compound is...

20060003030 - Essential oils for treating and/ or preventing allergic disease: The present invention provides the essential oil and the essential oil composition of traditional Chinese herbal medicine to prevent and/or treat allergic disease. The essential oil and the essential oil composition can be formulated as a solution, a cream, a lotion, ointment, or a solid stick, and applied topically....

20060003029 - Method for monitoring the quality of a herbal medicine: A method for monitoring the quality of a herbal medicine comprising the steps of: (a) providing a sample of the herbal medicine (b) extracting the sample with a polar solvent to produce a polar extract (c) subjecting the polar extract to ion-exchange chromatography to produce an extract enriched in ionic...

20060003031 - Perfumery for improved cold throw and burn in candle systems: A fragrance composition for use in hydrophobic systems, such as candles, comprising at least one odorant selected for having a minimum cold throw value (Ω) and a minimum hot throw value (η) is disclosed. A method of formulating a fragrance composition for hydrophobic systems, such as candles, comprising selecting at...

20060003032 - Dietary supplement composition for ameliorating inflammatory changes in influenza process: A dietary supplement composition comprising ginger, strobilanthes cusia, panax pseudoginseng, eucommia ulmoides, momordicae grosvenori, licorice root, and Allium fistulosum....

20060003033 - Topical compositions for anti-aging and methods of using same: A pharmaceutical composition for treatment of skin aging including a pharmaceutically effective amount of estriol; a pharmaceutically effective amount of estradiol; a pharmaceutically effective amount of hyaluronic acid; a pharmaceutically effective amount of green tea extract; and a pharmaceutically acceptable carrier is provided. In some embodiments, the composition further includes...

20060003034 - Stable cleanser compositions containing sulfur: The present invention is a composition, preferably a cleanser, comprising sulfur, sodium sulfacetamide and at least one emulsifier with a low HLB number. These compositions are stable and may include moisturizers and humectants. Use of these compositions include treatments for acne rosacea, acne vulgaris and other skin disorders....

20060003035 - [compositions and methods containing natural compounds from nonconventional sources that are useful in maintaining normal blood sugar levels]: The invention describes compositions and methods containing nonconventional plant materials, and more particularly the species Flemingia macrophylla and Careya arborea, that help to maintain normal blood sugar levels in humans and animals. The method of preparation of such compositions and methods of quantifying active principles therein are also described. A...

20060003036 - Solvent based plant extracts: The present invention relates to a method for producing petrochemical-free aroma components, which comprises extracting aroma components from plant materials with a volatile ester such as ethyl acetate. The method produces unique concrete, wax and absolute components that are useful in all types of fragranced compositions, which compositions, due to...