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Dna encoding human alpha and beta subunits of neuronal nicotinic acetylcholine receptor, cells transformed therewith, and a recombinant cell line expressing a functional human alpha7 subunit of neuronal nicotinic acetylcholine receptor

Abstract: Isolated nucleic acid molecules, i.e., DNA or RNA encoding human neuronal nicotinic acetylcholine receptor α and β subunits, mammalian and amphibian cells containing said DNA, methods for producing α and β subunits and recombinant (i.e., isolated or substantially pure) α subunits and β subunits are provided. In addition, cells expressing various multimeric combinations of subunits (i.e., α1, α2 α3 α4 α5 α6 and/or α7 in combination with at least one of an α and β subunit are also provided. A recombinant, non-human cell line expressing the human α7 subunit of nAChR is also disclosed. ...

USPTO Applicaton #: #20050287663 - Class: 435353000 (USPTO)

Related Patent Categories: Chemistry: Molecular Biology And Microbiology, Animal Cell, Per Se (e.g., Cell Lines, Etc.); Composition Thereof; Process Of Propagating, Maintaining Or Preserving An Animal Cell Or Composition Thereof; Process Of Isolating Or Separating An Animal Cell Or Composition Thereof; Process Of Preparing A Composition Containing An Animal Cell; Culture Media Therefore, Rodent Cell, Per Se, Rat (i.e., Rattus)
The Patent Description & Claims data below is from USPTO Patent Application 20050287663, Dna encoding human alpha and beta subunits of neuronal nicotinic acetylcholine receptor, cells transformed therewith, and a recombinant cell line expressing a functional human alpha7 subunit of neuronal nicotinic acetylcholine receptor.

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