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Device for taking and examining samplesRelated Patent Categories: Chemical Apparatus And Process Disinfecting, Deodorizing, Preserving, Or Sterilizing, Analyzer, Structured Indicator, Or Manipulative Laboratory Device, Miscellaneous Laboratory Apparatus And Elements, Per SeDevice for taking and examining samples description/claimsThe Patent Description & Claims data below is from USPTO Patent Application 20060093524, Device for taking and examining samples. Brief Patent Description - Full Patent Description - Patent Application Claims
[0001] The present invention relates to a device for taking and examining samples, in particular for the integrated taking of samples and examination by means of test methods, in particular immunological, chemical or biochemical kinds of tests. [0002] DE-C2-41 17 635 describes a multi-purpose examination device for fecal samples. This device comprises a housing with a cavity and a laterally arranged tube. A fecal sample is taken up by means of a stirring portion and introduced into the cavity, and this cavity is closed by means of a cap. An inner connection of the tube is wetted with the fecal sample. By means of a syringe, a highly sensitive reagent such as o-toluidine or tetramethyl benzhydrine and hydrogen peroxide is introduced into the cavity. Due to a color reaction it is tested whether the taken fecal sample contains traces of blood. For a further test, a slightly sensitive test reagent such as guaiac resin or lignum vitae resin and hydrogen peroxide are introduced through an opening at the free end of the tube. By observing a corresponding color reaction it is examined whether the fecal sample contains traces of blood. This examination device has a complicated design comprising a plurality of individual parts, and use thereof is difficult. [0003] EP-A2-0 327 144 describes a sample taking container and a method for processing a pasty sample material. A sample taking cup for taking a sample and introducing it into the sample-taking container is arranged at the cover of a container by means of a shaft. A liquid for suspending the fecal sample is contained in the sample-taking container. After introducing the sample cup and subsequently screwing on the container cover, the fecal sample disperses in the liquid. After transportation into a laboratory, the container cover is removed and a second liquid, in particular an organic solvent (ether or ethyl acetate) or colorant (e.g. Lugol's solution) is added. For the subsequent filtration, a separate filter body is screwed on, and by shaking the filtered suspension is obtained in the filtrate container. The filtered suspension can then be examined. This device comprises a plurality of individual parts, and use thereof is difficult. In particular, there is a danger that the liquid is spilled during use of the device. U.S. Pat. No. 4,978,504 describes a test unit for taking and analyzing samples. The test unit comprises a holder, and at one end of a small rod a taking sponge is arranged by means of which a sample can be taken. The holder comprises a cavity in which a destroyable ampulla containing a reaction fluid is provided. After taking a sample, the small rod is introduced into a tube-shaped housing, and the holding means is attached. Then, the ampulla is destroyed by impressing the holding means and the reaction fluid flows into the housing and comes in contact with the sample. Then the mixture is collected in a container or dropped onto a carrier and examined by means of separate devices. [0004] EP-A-0 520 408 describes a device which is suitable in particular for examining saliva samples. This test unit includes a cylindrical container containing a liquid and a sample collector shaped as a piston with a sponge arranged thereto for taking a saliva sample. After taking a sample, the sample collector is introduced into the housing and the sample collector sponge comes in contact with the liquid. The test device also comprises a collection container which can be attached to the other end of the housing and is displaceable with respect to the housing. In the interior of the collection container a thorn is arranged opposite of an opening at the other end of the housing, which opening is closed by a foil or sheet. In the attached position of the collection container, the foil or sheet is destroyed by the thorn and thus the opening is free. By introducing the piston-shaped sample collector completely, the liquid is pressed from the container into the collection container, and at the same time the sponge-like sample collector is pressed out. The collection container contains a reaction substance which reacts with the sample and the liquid, wherein this liquid is subsequently examined by means of a separate device. U.S. Pat. No. 5,393,496 describes a similar test device. [0005] It is an object of the present invention to provide a device for taking and examining samples which is designed in a simple manner and can be handled easily. [0006] This object is achieved with the features of the claims. It is a particular advantage of the device of the present invention that the samples can be taken easily, that the sample-taking means containing the sample can be safely introduced into a housing and can be mixed therein in a simple manner with a sample reprocessing liquid and that then the sample can be examined by means of a testing means arranged in the housing. [0007] A further advantage of the device according to the invention is that a sample reprocessing liquid is safely sealed in the cartridge and that the user does not come in contact with the sample also after mixing. [0008] In the following, the invention is explained in more detail on the basis of an embodiment and by referring to the drawings in which [0009] FIG. 1 is a basic sketch of the construction of a device according to the invention, [0010] FIG. 2 a partial view of an embodiment of a sample-taking means according to the invention seen from the handle, [0011] FIG. 3 a partial view of the sample-taking means according to FIG. 2 seen from the sample, [0012] FIG. 4 a basic sketch of the device according to the invention, and [0013] FIG. 5 an enlarged perspective partial view of the device according to FIG. 4. [0014] The device of FIG. 1 comprises a sample-taking means 10, a cartridge 30, a testing means 40 and a housing 50. As is indicated by the dashed lines, first the cartridge 30 is introduced into the tube-shaped housing 50 and subsequently the sample-taking means 10 is introduced into the housing 50 from the same side. A testing means 40 is introduced at the opposite side of the housing 50. Preferably, the cartridge 30 and/or the testing means 40 is displaceable within the housing 50 and secured against falling out. [0015] Preferably, the device is constructed in the above-described manner and provided to a user for taking a sample and examination thereof. This arrangement represents a test kit which can be used in a simple manner and can also be handled by laypersons, in particular elderly people. [0016] As shown in FIG. 2, the sample-taking means 10 consists of two half-tubes 11, 12 which form a tube (cylindrical cavity) when they are closed. The two half-tubes are connected with each other at one end (handle-facing end) by means of an elastic web 13 the stress of which presses the two halves apart so that they form a "V" when they are unstressed. In an alternative embodiment, the two half-tubes can be connected by a joint, wherein preferably the joint connection comprises a film hinge. For example, the film hinge can be arranged in a web connection between the half-tubes. Preferably, the web connection is shaped similar to the web 13 in FIG. 2 and the film hinge is arranged in the area of the pointed end. In this embodiment both half-tubes can be freely pivoted with respect to each other. If a spring action is desired, additional spring means can be provided. At the inner surface of the one half-tube 11 a triangular oblong recess 14 is arranged which can be engaged, with a corresponding counter groove 15 formed at the other half-tube 12. The recess 14 and the counter groove 15 form a guide which prevents the two half-tubes from moving out in the lateral direction when the sample-taking means is closed. At the handle-facing end of the outer surface of the half-tubes, a handling surface is provided with nubs 16 which prevent gliding-off during use. The handling surface is closed at the sample-facing side by a funnel-shaped, peripheral edge 17 which helps to avoid a contact with surplus sample material. At the sample-facing side of the peripheral edge 17 a steep thread 18 is formed at the outer surface of the tube consisting of the two half-tubes. [0017] As shown in FIG. 3, at the sample-facing end of the sample-taking means 10 a first disk 21 is arranged at the one half-tube 12 and, spaced therefrom, a second disk 22. When closing the sample-taking means, i.e. when the two half-tubes 11, 12 contact each other, said two disks form a sample chamber 20. From the distance a between the two disks and the radius r of the half-tubes, the sample volume V to be taken is calculated as follows: V=.pi.ra. The length of the half-tubes 11, 12 is dimensioned such that between the handle-facing disk 22 and the above-described guide 14, 15 there is a sufficient space for optionally surplus sample material. [0018] The sample-facing end disk 21 is connected to the inner surface of the half-tube 11 such that the connection resists to the forces caused during sample-taking; however, the disk 21 is broken out during introduction into the housing at one or a plurality of predetermined breaking points 23 by a resistance caused in the housing. A cone-shaped ring 24, the function of which is explained in more detail below, is attached to the outer edge of said disk 21. An indentation 25 is formed in the center of the disk 21. The area formed by this indentation corresponds to an opening of a truncated cone at the cartridge. Outside the indentation 25 the disk 21 has openings, so that a sieve 26 for mechanically opening the sample is realized. Instead of the indentation 25 a web, which will be described in more detail below, can be provided. [0019] The handle-facing disk 22 is rigidly attached so that it resists to all forces caused during sample-taking and sample-processing. [0020] With further reference to FIG. 4, the cartridge 30 is at first described in more detail. The cartridge 30 contains a liquid which is used, for example, for diluting and chemically opening the sample. The size of the interior space of the cartridge 30 and the amount of liquid M are selected such that the cartridge can take up the sample volume V in addition to the liquid already contained in the cartridge. The liquid amount M is provided in an exactly dosed relationship with respect to the given sample volume. The cartridge is shaped like a cylinder. At the edge facing the sample-taking means, the cylinder tapers so as to form a truncated cone 31; thus, the sieve 26 of the sample-taking means comprising the cone-shaped ring 24 centers itself on the cartridge. This cone-shaped seat preferably serves at the same time as a seal between the sample-taking means and the cartridge. At the end of the truncated cone of the cartridge, a circular impression 36 having an opening 32 in its center is formed. The opening is closed by a metal ball 33 arranged therein. The metal ball 33 is arranged in the opening for example by shrinking it on. In this case, the size of the metal ball 33 is slightly larger than the opening 32 at the cone-shaped end so that the ball can be pressed into the cartridge 30 when introducing the sample-taking means into the housing. Either the indentation 25 or a web arranged on the sieve is used for pressing the ball 33 in. A web is particularly advantageous if the ball is arranged in the cover surface of the cartridge in a recessed manner. The dimensions are selected such that preferably the cone surfaces are in a sealing contact as soon as the ball has been pressed completely into the cartridge. [0021] The opposite end of the cylindrical cartridge 30 is closed by a bottom 34 in the center of which there is an impression 35 which is also cylindrical and projects into the cartridge 30. Said impression 35 serves for taking up the testing means 40. The impression and the testing means are realized such that the wall of the impression 35 can be broken, and thus the content of the cartridge can be brought in contact with a test strip contained in the testing means. [0022] The testing means 40 has the shape of a cylinder and its cartridge-facing end tapers so as to form a truncated cone 41. At the tip of the truncated cone there is an opening 42 through which sample solution can enter. An absorbent material is introduced into the truncated cone, said absorbent material transporting the sample fluid to the test strip (not shown) by capillary forces. The cylindrical testing means 40 comprises one or a plurality of recesses so that color reactions of the test strip can be observed as a result of the test. The closing material is preferably a porous, water-repellent material which prevents the sample fluid from penetrating the testing means but which, however, allows the air displaced by the sample fluid to escape. [0023] The housing 50 serves for receiving, protecting and coordinating the above-described three components, i.e. the sample-taking means 10, the cartridge 30 and the testing means 40. It consists of a tube, the interior of which is divided into different diameters and the front portion of which has a thread 53. In the present embodiment, the front end serving as the introduction opening is funnel-shaped, has a high edge and preferably a considerably larger diameter than the sample-facing end of the sample-taking means. The frontal end 51 of the housing contacts the funnel-shaped, peripheral edge 17 and closes the introduction opening. Thus, a stripping chamber 52 is formed in which surplus sample material contained on the outer surface of the sample-facing end of the sample-taking means is stripped off and disposed. Following the stripping chamber 52, the diameter of the tube decreases so that the sample-facing end of the sample-taking means remains closed and can be displaced until it engages with a thread 53 at the inner surface of this portion. At the other part of the housing a sample-taking space 54 is provided which is adapted to the size and shape of the testing device 40 such that the tubular testing means 40 is held in it but can be moved back and forth when a slight pressure is applied. The center portion 55 contains the cartridge 30 which is held only by the testing means and hangs freely in any other respect and which can be displaced together with the testing means 40. [0024] By means of the above-described device, a test is carried out as follows. Continue reading about Device for taking and examining samples... Full patent description for Device for taking and examining samples Brief Patent Description - Full Patent Description - Patent Application Claims Click on the above for other options relating to this Device for taking and examining samples patent application. ###  How KEYWORD MONITOR works... a FREE service from FreshPatents1. Sign up (takes 30 seconds). 2. Fill in the keywords to be monitored. 3. Each week you receive an email with patent applications related to your keywords. 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