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12/27/07 - USPTO Class 600 |  113 views | #20070299331 | Prev - Next | About this Page  600 rss/xml feed  monitor keywords

Device for inducing vascular injury and/or blockage in an animal model

USPTO Application #: 20070299331
Title: Device for inducing vascular injury and/or blockage in an animal model
Abstract: Ultrashort laser pulses are used to induce photodisruptive breakdown in vasculature in an animal to controllably produce hemorrhage, thrombosis or breach of blood-brain barrier in individual, specifically targeted blood vessels. Damage is limited to the targeted vessels such that neighboring vessels exhibit no signs of vascular damage, including vessels directly above or below the targeted vessel. Ultrashort laser pulses of lower energy are also used to observe and quantify the baseline and altered states of blood flow. Observation and measurement may be performed (1) by TPLSM, OCT or other known techniques, providing a real-time, in vivo model for the dynamics and effects of vascular injury. (end of abstract)



Agent: Procopio, Cory, Hargreaves & Savitch LLP - San Diego, CA, US
Inventors: Beth FRIEDMAN, David KLEINFELD, Patrick D. LYDEN, Nozomi NISHIMURA, Christopher B. SCHAFFER, Lee Frederick SCHROEDER, Philbert TSAI
USPTO Applicaton #: 20070299331 - Class: 600407000 (USPTO)

Related Patent Categories: Surgery, Diagnostic Testing, Detecting Nuclear, Electromagnetic, Or Ultrasonic Radiation

Device for inducing vascular injury and/or blockage in an animal model description/claims


The Patent Description & Claims data below is from USPTO Patent Application 20070299331, Device for inducing vascular injury and/or blockage in an animal model.

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