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05/11/06 - USPTO Class 424 |  74 views | #20060099156 | Prev - Next | About this Page  424 rss/xml feed  monitor keywords

Dental whitening compositions

USPTO Application #: 20060099156
Title: Dental whitening compositions
Abstract: A two-component whitening system has a de-sensitizing effect as well as re-mineralizing capability. The system may be an unfoamed, a foamed or a foamable composition. The system has a first component with at least one peroxide compound, at least one source of phosphate and at least one gelling agent; and a second component with at least one source of calcium, strontium and/or mixtures thereof. The second component may also contain at least one gelling agent, and the composition maybe present as a foam or is foamable. The composition may be packed in a two-compartment syringe.
(end of abstract)
Agent: Discus Dental Impressions, Inc. - Culver City, CA, US
Inventors: Jeff MacDonald, Nancy N. Quan, Robert Hayman
USPTO Applicaton #: 20060099156 - Class: 424053000 (USPTO)

Related Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Dentifrices (includes Mouth Wash), Oxygen Or Chlorine Releasing Compound Containing

Dental whitening compositions description/claims


The Patent Description & Claims data below is from USPTO Patent Application 20060099156, Dental whitening compositions.

Brief Patent Description - Full Patent Description - Patent Application Claims
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CROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application claims the benefit of U.S. Provisional patent applications serial No. 60/626,407,filed Nov. 9, 2004, entitled "Tooth Whitening Compositions"; 60/631,121, filed Nov. 26, 2004, entitled "Whitening System"; 60/643,309, filed Jan. 22, 2005 entitled "Dental Whitening"; and 60/653,421, filed Feb. 15, 2005, entitled "Whitening System Capable of Effective Whitening Action"; the contents of which are hereby incorporated by reference.

FIELD OF THE INVENTION

[0002] The present invention relates to improvements in tooth treatment compositions. In particular, this invention relates to whitening compositions.

BACKGROUND OF THE INVENTION

[0003] A tooth is comprised of an inner dentin layer and an outer hard enamel that is coated with a protective layer called the acquired pellicle. The enamel layer is composed of hydroxyapatite crystals that create a somewhat porous surface. The pellicle or the enamel can become stained or discolored. It is believed that the porous nature of the enamel layer is what allows staining agents and discoloring substances to permeate the enamel and discolor the tooth.

[0004] Many substances that a person's teeth confront or come in contact with on a daily basis can "stain" or reduce the "whiteness" of one's teeth. In particular, food products, tobacco products and fluids such as tea and coffee that one consumes tend to stain one's teeth. These staining and discoloring substances can then permeate the enamel and cause noticeable discoloration of one's teeth. At the same time, some of the food and drinks can cause de-mineralization of the teeth.

[0005] One solution to the staining problem is through tooth bleaching. Some dentifrices, like toothpastes, gels, and powders, contain active oxygen or hydrogen peroxide liberating bleaching agents including peroxides, percarbonates and perborates of the alkali and alkaline earth metals or complex compounds containing hydrogen peroxide.

[0006] The amount of whitening obtained during tooth bleaching is dependent upon (1) the length of time each day the tray is worn; (2) the number of days the tray is worn; (3) the susceptibility of the teeth to the bleaching agent and (4) the concentration of active peroxides. For maximum whitening, an accelerated treatment time of approximately 18-20 hours per day is recommended.

[0007] One concern with some bleaching compositions is that prolonged treatment with highly concentrated bleaching agents present in the composition may contribute to tooth sensitivity following treatment. Even treatments with compositions not known to increase tooth sensitivity in most patients might still cause sensitivity in patients more prone to such sensitivity tendencies.

[0008] Another concern is that aggressive brushing, or any treatment with lower pH whitening compositions, as noted in Price et al. (The pH of Tooth-Whitening Products, J Can Dent Assoc, 66:421-6, 2000), may also lead to further de-mineralization of the tooth, decreasing its hardness.

[0009] Many attempts have been made to provide dentinal sensitivity relief, sometimes in a separate system from the bleaching system. Other attempts have been made to use a single system to attack both problems. At the same time, attempts have been made to re-mineralize the tooth, again in separate systems.

[0010] Therefore, there remains a need for a one-system approach to solving all the above mentioned problems and/or potential problems confronting the tooth.

SUMMARY OF THE INVENTION

[0011] The present invention relates to a one-system approach to whitening, sensitivity relief and re-mineralization.

[0012] The system may be a 2-component treatment composition having a first component including at least one peroxide compound, at least one source of phosphate and at least one gelling agent; and a second component including at least one source of calcium, strontium and/or mixtures thereof, and at least one gelling agent.

[0013] In one embodiment, the system may be a foamable composition.

[0014] In another embodiment, the first component may also contain a de-sensitizing agent.

[0015] The system also includes a 2-component foamed composition having a first component including at least one peroxide compound, at least one source of phosphate and at least one gelling agent; and a second component including at least one source of calcium, strontium and/or mixtures thereof.

[0016] The system further includes a 2-component foamable composition having a first component including at least one peroxide compound, at least one source of phosphate and at least one gelling agent; and a second component including at least one source of calcium, strontium and/or mixtures thereof, and at least one foaming agent.

[0017] In one embodiment of the invention, the second component may include at least one source of peroxide.

[0018] In another embodiment of the invention, the second component may include a de-sensitizing agent.

[0019] In yet another embodiment of the invention, both components may include a de-sensitizing agent.

[0020] In a further embodiment of the invention, the first component may also include a gel stabilizer.

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