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Decorin proteoglycan inhibitor of fibrinogen blood clotting pdficon_sm

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Abstract: The present invention provides compositions and methods of inhibiting fibrin(ogen) clot formation by utilizing decorin proteoglycan as an anticoagulating and antithrombotic agent. The decorin proteoglycan comprises a decorin core protein or a fragment thereof covalently linked to a galactosaminoglycan polysaccharide. The decorin core protein acts as an anticoagulant and as a carrier for the delivery of an antithrombotic galactosaminoglycan to fibrinogen. Fibrin clotting is inhibited by the decorin proteoglycan in a concentration-dependent fashion. ...


USPTO Applicaton #: #20060258570 - Class: 514008000 (USPTO)

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Related Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Designated Organic Active Ingredient Containing (doai), Peptide Containing (e.g., Protein, Peptones, Fibrinogen, Etc.) Doai, Glycoprotein (carbohydrate Containing)
The Patent Description & Claims data below is from USPTO Patent Application 20060258570, Decorin proteoglycan inhibitor of fibrinogen blood clotting.

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Actos   Anticoagulant   Blood Clot   Fibrin   Fibrinogen   Ibrin   Polysaccharide   


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