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Container with acid diffusion barrier and use thereofRelated Patent Categories: Stock Material Or Miscellaneous Articles, Hollow Or Container Type Article (e.g., Tube, Vase, Etc.), Polymer Or Resin Containing (i.e., Natural Or Synthetic)Container with acid diffusion barrier and use thereof description/claimsThe Patent Description & Claims data below is from USPTO Patent Application 20060210739, Container with acid diffusion barrier and use thereof. Brief Patent Description - Full Patent Description - Patent Application Claims
TECHNICAL FIELD OF THE INVENTION [0001] The present invention relates to a container having a wall structure comprising a polymer material including an acid diffusion barrier. [0002] The invention also relates to a use of a cycloolefin polymer, COP, and/or a cycloolefin copolymer, COC, as an acid diffusion barrier polymer in a container for an acid. [0003] The invention further relates to a use of such a container and to a system for providing a medical solution comprising at least one container according to the invention. [0004] Finally the invention relates to a method for treatment by means of a container according to the invention. BACKGROUND OF THE INVENTION [0005] Containers for accommodation of an acid in fluid or in powder form are employed in many different applications within the chemical, technological, medical, pharmaceutical and food field, among others. One application is within the medical field where polymer containers for containing an acid are used. The container may e g be a supply bag for a medical purpose where the container contains an acid fluid in, or for the preparation of, a resulting sterile or non-sterile medical solution. For example, the acid fluid may be used in a dialysis fluid for buffering causes in order to take care of toxic substances in a patient that suffers from a kidney disease. Such a dialysis fluid is for example intended for hemodialysis, hemodiafiltration, hemofiltration, peritoneal dialysis, intensive care fluid management, nutrition compounds, concentrates, lavage fluids or infusion therapies. The acid serves to balance the pH-value of a fluid so that the resulting medical solution has a physiological pH that is substantially neutral, i e a pH value between 6.5 and 8, preferably between 7.0 and 7.4. [0006] As the acid in the container diffuses through the wall structure to the outside of the container over time, it is necessary to secure an allowable permeation by diffusion through the wall of the container. Diffusion in excess of certain limits will adversely affect the composition of the resulting solution. It is especially important to control diffusion in medical solutions, as an unacceptable change in pH and in concentrations of electrolytes and glucose will negatively affect the patient. Examples of acids used in medical solutions are acetic, citric, gluconic, lactic, carbonic and hydrochloric acids, etc. [0007] If the acid is of the bad smelling type, as for example acetic acid, a disadvantageous effect of diffusion is that an odour is connected to the container. A further disadvantage is the risk that materials that come in contact with the container may corrode and degradation products may enter into the fluid and cause deleterious effects. It is especially important that the diffusion of the acid through the wall of the container is limited in cases where the container needs to be stored while containing the acid to avoid change in composition. [0008] Containers within the prior art intended for containing acid are normally made of a polymer film. However, all polymer materials are not suitable for the purpose of containing an acid as interaction with highly concentrated acid may result in extraction of toxic additives or polymeric components from the polymer material, which may cause problems when the acid is used. Prior art containers are for example single or multilayer flexible, semirigid or rigid containers made of polyolefin (polypropylene, PP, or polyethylene, PE), polyamide, PA, ethylene vinyl acetate, EVA, and/or ethylene vinyl alcohol, EVOH. The film may be a single-layer film, which for example is extruded, or a multi-layer film, which for example is coextruded or laminated. The prior art containers having walls made of these polymer films ensure general chemical resistance and low water uptake but have the disadvantage that the velocity of diffusion of acid through the wall is high and not acceptable when the acid concentration in the container is increased. To overcome this drawback the acid is diluted to such an extent that the velocity of diffusion is acceptable over time. However, dilution of the acid results in that the amount of acid fluid is larger than actually needed as well as the container. A known container of Gambro AB, SelectBag.TM., for acid fluid have for example an acid concentration of 7%. This acid fluid is then mixed with further substances and diluted 400 times by a defined dilution operation before used in a dialysis machine for dialysis treatment of a patient. [0009] An alternative way to overcome the drawback with increased diffusion velocity, when the concentration of acid is increased in the polymer container, is to provide containers with increased wall thickness. Increased wall thickness, however, results in increased weight, production and transportation costs, consumption of materials and environmental impact. Further, an increased wall thickness involves reduced flexibility of the container. [0010] Normally, when high concentrations of acid are to be stored, glass bottles or bottles that provide an acceptable barrier against diffusion of acid are used. Glass bottles though, are heavy and unpractical to handle and expensive to manufacture and transport. [0011] It is highly desirable to use highly concentrated acids and other dialysis components in order to refine and improve dialysis procedure, for example individualizing dialysis treatment and creating logistic advantages by lower fluid volumes. SUMMARY OF THE INVENTION [0012] The object of the present invention is to provide a container for an acid, wherein the above-mentioned drawbacks have been eliminated or alleviated. [0013] According to the present invention this object has been achieved by a container having a wall structure comprising a polymer material, characterized in that the polymer material includes an acid diffusion barrier comprising a cycloolefin polymer, COP, and/or a cycloolefin copolymer, COC, and that the container contains an acid. Preferred embodiments of the container are set forth in the enclosed dependent claims 2-19 and in the following description. [0014] Another object of the invention is to provide a use of a cycloolefin polymer, COP, and/or a cycloolefin copolymer, COC, as an acid diffusion barrier polymer in a container for an acid. [0015] A further object is to provide a use of the container of the invention for storing a medical solution for hemodialysis, hemodiafiltration, hemofiltration, peritoneal dialysis, intensive care fluid management, nutrition compounds, concentrates, lavage fluids or for infusion therapies. [0016] Yet another object is to achieve a system providing a medical solution comprising at least one container according to the invention. Preferred embodiments of the system are set forth in the enclosed dependent claims 23 and 24 and in the following description. [0017] Finally, an object of the present invention is to provide a method for treatment by hemodialysis, hemodiafiltration, hemofiltration, peritoneal dialysis, intensive care fluid management, nutrition compounds, concentrates, lavage fluids or infusion therapies by means of a container according to any of claims 1-19. [0018] By the invention a container is achieved which has a decreased permeability of acid compared to prior art and thereby a decreased diffusion of acid so that the diffusion of acid is acceptable over time. [0019] Another advantage is that the concentration of acid may be chosen in the whole range of 0-100%. This means that highly concentrated acid may be contained in the container. By utilizing less diluted acid a smaller container is required, which means decreased weight, production and transportation costs, consumption of material and environmental effect. Alternatively the amount of acid is increased while keeping the same size of the bag so as to provide a container for an acid containing medical solution where the medical solution lasts for longer treatments. [0020] A further advantage of the invention is that the wall thickness may be kept small so that a convenient flexibility of the container may be chosen. [0021] Yet another advantage is that a less loss of acid increases the time possible to store the acid-containing container, i e increased shelf life is achieved. Continue reading about Container with acid diffusion barrier and use thereof... Full patent description for Container with acid diffusion barrier and use thereof Brief Patent Description - Full Patent Description - Patent Application Claims Click on the above for other options relating to this Container with acid diffusion barrier and use thereof patent application. ###  How KEYWORD MONITOR works... a FREE service from FreshPatents1. Sign up (takes 30 seconds). 2. Fill in the keywords to be monitored. 3. Each week you receive an email with patent applications related to your keywords. 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