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12/27/07 - USPTO Class 435 |  44 views | #20070298420 | Prev - Next | About this Page  435 rss/xml feed  monitor keywords

Cholesterol transport gene

USPTO Application #: 20070298420
Title: Cholesterol transport gene
Abstract: Methods and compounds are disclosed for lowering serum LDL levels or serum cholesterol levels, or for reducing the transport of cholesterol from the gut to the blood or the lymph, based on the observation that a gene known as ABC1 is necessary in order for cholesterol to be transported from the intestinal lumen into the bloodstream. A mutant chicken phenotype, known as the WHAM chicken, characterized by low levels of serum LDL and reduced transport of cholesterol, facilitated the discovery of this function of the ABC1 gene. Techniques which act to inhibit ABC1 activity in the cells of the intestinal wall will result in lower serum cholesterol. (end of abstract)



Agent: Quarles & Brady LLP - Madison, WI, US
Inventors: Alan D. Attie, Mark Cook, Mark P. Gray-Keller, Michael R. Hayden, Simon Pimstone, Angela R. Brooks-Wilson
USPTO Applicaton #: 20070298420 - Class: 435006000 (USPTO)

Related Patent Categories: Chemistry: Molecular Biology And Microbiology, Measuring Or Testing Process Involving Enzymes Or Micro-organisms; Composition Or Test Strip Therefore; Processes Of Forming Such Composition Or Test Strip, Involving Nucleic Acid

Cholesterol transport gene description/claims


The Patent Description & Claims data below is from USPTO Patent Application 20070298420, Cholesterol transport gene.

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