Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof inventions 11/07

20070276123 - Amyloid formation: A protein must fold into a specific conformation in order to carry out its intended function. Failure to fold correctly may lead to self-association and aggregation, and formation of a highly ordered and insoluble form of protein—the amyloid fibril. Amyloid fibrils are associated with a growing number of human diseases... Agent: Edwards Angell Palmer & Dodge LLP

20070276124 - Protein expression: The invention provides a peptide having at least about 75% amino acid homology with the sequence shown in SEQ ID No: 2. The peptide of the invention also can include an amino acid homology with the sequence shown in SEQ ID No: 2 corresponding to at least about 80%, at... Agent: Mcdermott, Will & Emery

20070276125 - Methods for inhibiting immune complex formation in a subject: Polypeptides and other compounds that can bind specifically to the CH2-CH3 cleft of an immunoglobulin molecule, and methods for using such polypeptides and compounds to inhibit Fc-mediated immune complex formation, are described.... Agent: Fish & Richardson P.C.

20070276126 - Cell adhesion and extracellular matrix proteins: Various embodiments of the invention provide human cell adhesion and extracellular matrix proteins (CADECM) and polynucleotides which identify and encode CADECM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of... Agent: Foley And Lardner LLP Suite 500

20070276127 - Protein composition obtained from a muscle source: A process is provided for isolating a protein component of animal muscle tissue by mixing a particulate form of the tissue with an acidic aqueous liquid having a pH below about 3.5 to produce a protein rich solution substantially free of myofibrils and sarcomere tissue structure. The protein rich aqueous... Agent: Paul J. Cook

20070276128 - Stabilized proteins with engineered disulfide bonds: The present invention relates to methods of introducing one or more cysteine residues into a polypeptide which permit the stabilization of the polypeptide by formation of at least one bond, preferably a disulfide bond, between different domains of the polypeptide. The invention also relates to polypeptides containing such introduced cysteine... Agent: Morgan & Finnegan, L.L.P.

20070276129 - Modular molecular clasps and uses thereof: The present invention provides Modular Molecular Clasps and methods of using these Modular Molecular Clasps in a wide range of applications in the health care industry, e.g., in therapy, in clinical diagnostics, in in vivo imaging or in drug discovery. The Modular Molecular Clasps of the present invention also have... Agent: Goodwin Procter LLP Patent Administrator

20070276130 - Rotavirus antigens: The present invention relates to novel recombinant polypeptide antigens that may comprise subunit vaccines against rotavirus infection. Further, the present invention relates to methods for use of said antigens in the diagnosis, treatment and prevention of rotavirus infection.... Agent: Foley Hoag, LLP Patent Group, World Trade Center West

20070276131 - Continuous process for the assembly of macromolecular substances and the subsequent capture and isolation of mamacromolecular assembly and a system suitable for the process: The present invention relates to a continuous process and a system for macromolecular assembly and capture (refolding or proteins (e.g. refolding of HAT human β2-microglobulin), hybridization of nucleic acid, nucleic acid analogues, and protein-nucleic acid chimera, aggregation of carbohydrates, and assembly of nanostructures/nanomaterials. The process may comprise the steps of... Agent: Foley And Lardner LLP Suite 500

20070270572 - Conformational switches in toxin folding and uses thereof: There is provided a method of altering the conformation of a peptide from a globular conformation to a ribbon conformation or vice versa comprising removing or introducing a conformation-inducing residue into the peptide. In particular, there is provided a method of altering the conformation of a peptide, the method comprising... Agent: Carol Nottenburg

20070270573 - Microwave enhanced n-fmoc deprotection in peptide synthesis: A method is disclosed for carrying out peptide synthesis comprising deprotecting an Fmoc-protected amino acid with piperazine while applying microwave irradiation to the deprotection reaction.... Agent: Summa, Allan & Additon, P.A.

20070270575 - Protein showing enhanced expression in cancer cells: A novel gene (designated 101P3A11 or PHOR-1) and its encoded protein, and variants thereof, are described wherein 101P3A11 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 101P3A11 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The... Agent: Agensys C/o Morrison & Foerster LLP

20070270574 - Subtilisin variants: New subtilisin homologues (both nucleic acids and proteins) are provided. Compositions which include these new proteins, recombinant cells, shuffling methods involving the new homologues, antibodies to the new homologues, and methods of using the homologues are also provided.... Agent: Novozymes North America, Inc.

20070270576 - Flea head, nerve cord, hindgut and malpighian tubule nucleic acid molecules, proteins and uses thereof: The present invention relates to flea head, nerve cord, hindgut and Malpighian tubule proteins; to flea head, nerve cord, hindgut and Malpighian tubule nucleic acid molecules, including those that encode such flea head, nerve cord, hindgut and Malpighian tubule proteins; to antibodies raised against such flea head, nerve cord, hindgut... Agent: Heska Corporation Intellectual Property Dept

20070270577 - Increased recovery of active proteins: The invention provides methods of increasing yields of desired conformation of proteins. In particular embodiments, the invention includes contacting preparations of a recombinant protein with a reduction/oxidation coupling reagent for a time sufficient to increase the relative proportion of a desired configurational isomer.... Agent: Immunex Corporation Law Department

20070265430 - Fluorescent polypeptide complex: The present invention relates to a method of producing a fluorescent polypeptide complex characterized in that an isolated fluorescent polypeptide is inter-molecularly cross-linked with itself or one or more other polypeptides and wherein said complex is of 40 nm to 500 nm in size, it also relates to a complex... Agent: Roche Diagnostics Operations Inc.

20070265431 - Pmma binding peptides and methods of use: Combinatorially generated peptides are provided that have binding affinity for polymethylmethacrylate (PMMA). The peptides may be used to deliver benefit agents to various PMMA surfaces.... Agent: E I Du Pont De Nemours And Company Legal Patent Records Center

20070265432 - Multiplex-bead complex for determination of lysosomal storage disorders: Multiplexing bead technology is used for simultaneous screening of multiple LSD and normalizing measured enzyme activity or protein levels against other lysosomal proteins, enzymes, or enzyme activities. Diagnostic compositions include microspheres conjugated to purified antibodies that specifically bind LSD target antigens: saposin, LAMP-1, α-iduronidase, α-glucosidase, β-glucosidase, 2-sulphatase, 4-sulphatase, α-galactosidase, sphingomyelinase,... Agent: Jackson Walker LLP

20070265433 - Process and materials for the rapid detection of streptococcus pneumoniae employing purified antigen-specific antibodies: Disclosed is a cell wall C-polysaccharide antigen of Streptococcus pneumoniae which contains not more than 10% by weight of protein, and preferably less which has been purified with 0.1N Na OH prior to deproteinizing. Also disclosed are polyvalent antibodies raised against Streptococcus pneumoniae which have been affinity purified by passing... Agent: Foley Hoag, LLP Patent Group (w/isa)

20070260039 - Methods of producing silk polypeptides and products thereof: The invention provides a silk polypeptide comprising a plurality of repetitive units and a non-repetitive hydrophilic amino acid domain, polynucleotides and vectors encoding silk polypeptides, methods of expressing the silk polypeptide in host cells and transgenic animals, and methods of forming a biofilament comprised of silkpolypeptides.... Agent: Jones Day

20070260041 - Allylic disulfide rearrangement and desulfurization method for the preparation of allylic sulfides: A method for the preparation of an allylic sulfide comprises contacting an activated sulfenyl compound of Formula (I) with a thiol of Formula (II) for a period of time sufficient to form an intermediate of Formula (III), and contacting the intermediate of Formula (III) with a thiophilic agent, in a... Agent: Olson & Hierl, Ltd.

20070260040 - Amino acid surrogates for peptidic constructs: where R1, R2, R3, R4, R5, R6a, R6b, R7, and y are as defined in the specification, methods for synthesizing ring-constrained amino acid surrogates of formula I, methods of use of ring-constrained amino acid surrogates of formula I, including use in linear or cyclic compounds which include a plurality of... Agent: Palatin Technologies, Inc.

20070260042 - Human mast cell-expressed membrane protein (gpcr): Motifs and patterns are generated by computer and printed on fabric, paper or plastic materials in continuous non-repeating patterns. The data is produced automatically by a random math algorithm, so that each of the printed patterns is similar, but not identical. The layout is arranged in a random manner, so... Agent: Cheryl Liljestrand Tanox Inc

20070260043 - Method for producing a low reducing agent-containing keratin and products thereof: The invention pertains to a method for producing a low reducing agent-containing keratin, comprises the steps of (a) cleaving disulfide (CysS-SCys) bonds in a keratin-containing starting material, using a reducing agent in an aqueous medium, to obtain an intermediate keratin product wherein at least 90% of cleaved disulfide bonds have... Agent: Oliff & Berridge, PLC

20070260044 - R-alpha1 antitrypsin anion exchange chromatography: The present invention relates to a method for obtaining highly purified recombinant alpha1-antitrypsin (rAAT) using anion exchange chromatography, wherein a composition comprising rAAT and at least one impurity originating from cultivation of cells used for generating of rAAT is loaded onto a column containing anion exchange material and the anion... Agent: Baxter Healthcare Corporation

20070260045 - Secreted and transmembrane polypeptides and nucleic acids encoding the same: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides... Agent: Heller Ehrman LLP

20070260046 - Dispersant using kraft lignin and novel lignin derivative: The dispersant of the present invention comprises at least one component unit derived from kraft lignin and/or its salt and at least one component unit derived from at least one water-soluble monomer. The novel lignin derivative of the present invention comprises at least one component unit derived from kraft lignin... Agent: Wenderoth, Lind & Ponack, L.L.P.

20070255041 - Bioengineered vehicles for targeted nucleic acid delivery: There is disclosed a gene-delivery compound comprising: (A) a single-chain binding polypeptide having at least one effector segment which includes at least one cysteinyl residue; and (B) a nucleic acid-binding moiety which is coupled to the polypeptide via the cysteinyl residue. There is disclosed also a gene-delivery compound comprising: (A)... Agent: Synnestvedt & Lechner, LLP

20070255042 - Production of chiral materials using crystallization inhibitors: A method is disclosed for producing a chiral gel. A polymer including chiral monomers, such as a protein, is dissolved to generate a sol, which is optionally dialyzed. The sol is contacted with a crystallization inhibitor that allows it to form a gel. The gel in wet or dried form... Agent: Wilmer Cutler Pickering Hale And Dorr LLP

20070255044 - Mammalian galanin receptors: The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind... Agent: Schering-plough Corporation Patent Department (k-6-1, 1990)

20070255043 - Mn gene and protein: A new gene—MN—and proteins/polypeptides encoded therefrom are disclosed. Recombinant nucleic acid molecules for expressing MN proteins/polypeptides and recombinant proteins are provided. Expression of the MN gene is disclosed as being associated with tumorigenicity, and the invention concerns methods and compositions for detecting and/or quantitating MN antigen and/or MN-specific antibodies in... Agent: Leona L. Lauder Attorney At Law