Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof inventions 08/07

20070203325 - Integrase-dirived hiv-inhibiting agents: The present invention relates to agents based on integrase of HIV-1, for inhibiting the proliferation of HIV-1. The agents are derived from the C-terminal domain of HIV-1 integrase, comprising at least one of the regions identified as being important for interaction between integrase and imp7 or impβ, and/or for nuclear... Agent: Smart & Biggar P.o. Box 2999, Station D

20070203326 - Integrin-linked kinase and its uses: Methods for isolating ILK genes are provided. The ILK nucleic acid compositions find use in identifying homologous or related proteins and the DNA sequences encoding such proteins; in producing compositions that modulate the expression or function of the protein; and in studying associated physiological pathways. In addition, modulation of the... Agent: Bozicevic, Field & Francis LLP

20070203329 - Activin receptor-like kinases, proteins having serine threonine kinase domains and their use: A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-beta-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.... Agent: Fulbright & Jaworski, LLP

20070203328 - Novel hemopoietin receptor protein, nr12: A novel hemopoietin receptor gene (NR12) was successfully isolated by extracting motifs conserved among the amino acid sequences of known hemopoietin receptors and by using the predicted sequence. The NR12 gene encodes two forms of proteins, a transmembrane type and a soluble type. The expression of the NR12 gene was... Agent: Fish & Richardson PC

20070203327 - Transcription factor of mhc class ii genes, substances capable of inhibiting this transcription factor and medical uses of these substanaces: The present invention relates to a transcription factor of MHC class II genes and its derivatives, inhibitors down-regulating the expression of MHC class II molecules, process to identify these inhibitors and medical uses of these inhibitors.... Agent: Mintz, Levin, Cohn, Ferris, Glovsky And Popeo, P.C.

20070203330 - Process for removing fibronectin from plasma fractions: The invention relates to a method for separating fibronectin from plasma fractions by adjusting a pH value of less than 5.4 such that fibronectin is precipitated and extracted from the solution.... Agent: Smith Patent Consulting Consulting, LLC

20070197771 - Methods for the synthesis of two or more dicarba bridges in organic compounds: Described herein are methods for forming two or more dicarba bridges, as well as new compounds containing dicarba bridges.... Agent: Fish & Richardson PC

20070197772 - Methods for preparing internally constrained peptides and peptidomimetics: The present invention relates to a method for preparing a peptide having a stable, internally constrained alpha-helical, beta-sheet/beta-turn, 310-helical, or pi-helical region and a method of stabilizing an alpha-helical, beta-sheet/beta-turn, 310-helical, or pi-helical region within a peptide structure. The resulting peptides and methods of using them are also disclosed.... Agent: Nixon Peabody LLP - Patent Group

20070197773 - Methods and systems for generating and evaluating peptides: A method has been developed to create databases of peptides having a desirable property, such as antimicrobial activity, based on analyzing a database of known peptides for a pattern statistically associated with an activity. One can determine a set of patterns that may be representative of a peptide having a... Agent: Patrea L. Pabst Pabst Patent Group LLP

20070197774 - Adrenocorticotropic hormone analogs and related methods: ACTH analog compounds of the present invention include compounds comprising an ACTH peptide sequence with one or more structural modifications that can have one or more of the following preferred ACTH analog biological functions: (1) reduction of corticosteroid secretion by adrenal membrane in the presence of the ACTH analog compared... Agent: Indianapolis Office 27879 Brinks Hofer Gilson & Lione

20070197775 - Cytotoxic agents comprising taxanes and their therapeutic use: A cytotoxic agent comprising one or more taxanes linked to a cell binding agent. A therapeutic composition for killing selected cell populations comprising: (A) a cytotoxic amount of one or more taxanes covalently bonded to a cell binding agent through a linking group, and (B) a pharmaceutically acceptable carrier, diluent... Agent: Sughrue, Mion, Zinn, Macpeak & Seas, PLLC

20070197776 - Hydrogels for protein concentration: Proteinaceous gels having visualization agents and methods of use thereof are disclosed herein. Further, polymeric crosslinking agents are disclosed that have an inert water soluble polymeric component, biodegradable components, functional components reactive with chemical groups on a protein, for example, amine or thiol groups. The inert polymeric component may be... Agent: Dardi & Associates, PLLC

20070197777 - Cloning and expression of outer membrane protein c of salmonella typhi ty2 and conjugation of the purified insoluble protein to vi-polysaccharide for use as a vaccine for typhoid fever: The invention relates to a novel carrier protein for use as a vaccine comprising the outer membrane protein C (OmpC) of Salmonella typhi Ty2 for conjugation with VI polysaccharide.... Agent: The Webb Law Firm, P.C.

20070197778 - Novel coumarin derivative: A compound represented by the following general formula (I) or a salt thereof [R1 represents hydrogen atom, or a C1-12 alkyl group; R2 represents a C1-12 alkyl group having one or more maleimide groups, an aryl group having two or more maleimide groups, a group represented by the formula (A):... Agent: Greenblum & Bernstein, P.L.C

20070191590 - Method for crystallization of proteins using polysaccharides: The objective of the invention is a crystallizing method for macromolecules, especially proteins and polypeptides, in which selected polysaccharides of biological origin, such as alginate, pectin, dextrin or chitosan and hydrolysates thereof, are used as reagents. Sedimentation of the crystals can be prevented and thus the uniformity of the product... Agent: Ostrolenk Faber Gerb & Soffen

20070191591 - Smurf1 independent mechanism of osteoinduction of lmp-3 protein: Novel osteogenic compositions and methods are provided. In a broad aspect, the composition comprises either a first amino acid sequence which is capable of being phosphorylated by CAMK2; or a nucleic acid sequence encoding the first amino acid sequence; or a combination thereof. Optionally, the first amino acid sequence may... Agent: Fox Rothschild, LLP

20070191592 - Urocortin proteins and uses thereof: A human urocortin-related peptide with significant sequence homology to the CRF neuropeptide family was identified. A mouse CDNA was isolated from whole brain poly (A+) RNA that encodes a predicted 38 amino acid peptide protein designated herein as urocortin II. Both human URP and mouse Ucn II are structurally related... Agent: Seed Intellectual Property Law Group PLLC

20070191593 - Process for preparation of flax protein isolate: Flax protein isolates are obtained in a procedure in which flax oil seeds are initially extracted to remove mucilage therefrom prior to crushing to recover the oil and produce a meal. The flax protein meal then is processed to recover a flax protein isolate therefrom.... Agent: Sim & Mcburney

20070191594 - Protein purification: Described herein are methods for purifying a protein of interest from a mixture of proteins wherein the mixture comprises the protein of interest and a fusion analog thereof. The method begins with a recovery in which filtration is used to remove cells and concentrate the protein of interest. Liquid chromatography... Agent: Genencor International, Inc.

20070191595 - 6-monoacetylmorphine derivatives useful in immunoassay: Analogs of 6-monoacetyl morphine (6-MAM) are described. These include analogs derivatized at either the C-3 position, the C-6 position, or the nor position of the molecule. These analogs allow for elaboration with linkers terminated by a functional group such as an activated ester, the functional groups being useful for attaching... Agent: Roche Diagnostics Operations Inc.

20070191596 - Device and method for filtration and/or separation of molecules, particularly proteins: The present invention concerns a device and a method for filtering molecules that is precise, efficient, reliable, and rapid; it has a low rate of molecular loss, it can be upgraded, and it provides for the automated filtration of molecules according to one or more predefined parameters. The device (10)... Agent: Davis & Bujold, P.l.l.c.

20070185310 - Thermal- and chemical-resistant acid protection coating material and spin-on thermoplastic adhesive: New compositions for use as protective coatings and/or adhesives are provided. The compositions comprise a hydrocarbon resin (e.g., terpene rosin) and a rubber (e.g., EPDM) dispersed or dissolved in a solvent system. The solvent system is preferably a single-solvent system, and the compositions are preferably free of surfactants, dyes, and... Agent: Hovey Williams LLP

20070185311 - Peptide-based multimeric targeted contrast agents: Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.... Agent: Fish & Richardson P.C.

20070185314 - Crystals of luxp and complexes thereof: A crystal comprising LuxP is obtained, and a binding site for autoinducer-2 (AI-2) identified. The X-ray crystallographic data for LuxP and a LuxP-AI-2 complex is determined and used in a drug discovery method. Pharmaceutical compositions comprising ligands identified by such drug discovery methods are used to treat bacterial infections.... Agent: Mathews, Shepherd, Mckay, & Bruneau, P.A.

20070185313 - Human neuronal nicotinic acetylcholine receptor compositions and methods employing same: DNA encoding human neuronal nicotinic acetylcholine receptor alpha and beta subunits, mammalian and amphibian cells containing said DNA, methods for producing alpha and beta subunits and recombinant (i.e., isolated or substantially pure) alpha subunits (specifically α6) and beta subunits (specifically β3) are provided. In addition, combinations of a plurality of... Agent: Merck And Co., Inc

20070185312 - Nucleic acids encoding a g-protein coupled receptor involved in sensory transduction: The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sensory cell specific G-protein coupled receptors.... Agent: Townsend And Townsend And Crew, LLP

20070185315 - Novel albumins: The present invention relates to mutated forms of serum albumin, which display altered metal binding and/or other characteristics with respect to a native albumin from which the mutant has been derived, as well as uses of such mutant albumins in the medical field or in growth of cells in culture.... Agent: Morgan, Lewis & Bockius, LLP.

20070185316 - Method for tagging of carbohydrates with active methylene compound: The present invention relates to the method for tagging of carbohydrates with active methylene compound. Particularly, it relates to the method for tagging of carbohydrates with active methylene compound comprising the step of preparing carbohydrate conjugate in which carbohydrate and methylene compound are combined by mixing carbohydrate mixture and methylene... Agent: Jhk Law

20070179277 - Rosin ester with low color and process for preparing same: A process for producing light color rosins ester resin, preferably based on tall rosin, is described. The process is conducted in the presence of less than 10 weight % of an acid functional organic compound and avoids the need for use of a stoichiometric excess of rosin acid, or a... Agent: Hexion Specialty Chemicals, Inc.

20070179278 - Hiv fusion inhibitor peptides with improved biological properties: Provided is an HIV fusion inhibitor peptide having an amino acid sequence of any one of SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, or SEQ ID NO:15; and provided is a pharmaceutical composition comprising a HIV fusion inhibitor peptide... Agent: Jones Day

20070179279 - Methods for the synthesis of arginine-containing peptides: Methods for the synthesis of arginine-containing peptides are provided. The methods include a step that minimizes contact of side chain protected arginine with base prior to the coupling step.... Agent: Roche Colorado Corporation

20070179281 - Bont/a peptides and methods of predicting and reducing immunoresistance to botulinum toxin therapy: The present invention provides BoNT/A peptides as well as methods of predicting or determining immunoresistance to botulinum toxin therapy in an individual using BoNT/A peptides.... Agent: Mcdermott, Will & Emery

20070179280 - Highly purified proteinase k: A method for producing solid proteinase K which is insoluble in water and has high purity, the method comprising the steps of adding to an aqueous solution of proteinase K ammonium sulfate in an amount of 0.1 to 0.2 M per 5 minutes up to a final amount of 1.5... Agent: Roche Diagnostics Operations Inc.

20070179282 - Pressure cryocooling protein crystals: Preparation of cryocooled protein crystal is provided by use of helium pressurizing and cryocooling to obtain cryocooled protein crystal allowing collection of high resolution data and by heavier noble gas (krypton or xenon) binding followed by helium pressurizing and cryocooling to obtain cryocooled protein crystal for collection of high resolution... Agent: Bacon & Thomas, PLLC

20070179283 - Extraction process for a pharmaceutical product: A process for isolating a soluble, native collagen from a marine invertebrate, comprising the steps of: 1) treating a collagen-containing portion of the marine invertebrate with a weak acid solution in order to solubilise native collagen fibrils; 2) centrifuging the resultant slurry to remove tissue particulates; 3) adjusting the pH... Agent: Moore & Van Allen PLLC

20070179284 - Insecticidal plant cyclotide with activity against homopteran insects: The present invention relates to isolated nucleic acids encoding plant cyclotides. The invention also relates to the construction of a chimeric gene encoding all or a portion of the plant cyclotides, in sense or antisense orientation, wherein expression of the chimeric gene results in the production of altered levels of... Agent: Pioneer Hi-bred International, Inc.