Chemistry: analytical and immunological testing inventions

20090263903 - Method for determining prothrombin time: The present invention relates to tests for monitoring oral anticoagulation therapy and hepatocellular carcinoma (HCC). Particularly, the invention provides a method for determining prothrombin time of a plasma or whole blood sample taking account the effect which protein induced by vitamin K absence or antagonists (Pivka) has on clotting time... Agent: Brooks Kushman P.C.

20090263904 - Assay apparatuses, methods and reagents: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air... Agent: Nixon & Vanderhye, PC

20090263905 - Detection test assembly for detecting the presence of a substance in a sample: A detection test assembly for detecting the presence of a substance preferably a blood substance in a feces sample comprising feces diluted in buffer solution or water is described. The blood substance is detected by acceptors having binding properties for the substance or that may be specifically bound by the... Agent: Ladas & Parry LLP

20090263906 - Method of antioxidative functional estimation using animal model: The present invention relates to a method of antioxidative functional estimation using an animal model, more precisely a method of antioxidative functional estimation using mice having oxidative damage caused by reactive oxygen species induced by irradiation and having lipid hydroperoxide secreted in the urine which might be index for quantitative... Agent: Greenlee Winner And Sullivan P C

20090263907 - Reagent for lead concentration determination and method of determining lead concentration: e

20090263908 - Liquid crystal condensation of nucleic acid (na) complexes: Upon cooling solutions or melts of nucleic acids or other polymers in which the constituent molecules exhibit a varying tendency to form multi-strand complexes and thus liquid crystal phases, the complex-forming oligomers preferentially separate into the liquid crystal phase and condensing into liquid crystal domains. Because the tendency for liquid... Agent: Lathrop & Gage LLP

20090263909 - Treatment of nucleic acid: Methods for treating nucleic acid including: (a) providing an alkali environment to a nucleic acid sample; (b) reacting the nucleic acid sample with a bisulphite reagent and incubating the reaction so as to form a treated nucleic acid sample where methylated nucleotides in the nucleic acid sample remain unchanged while... Agent: Knobbe Martens Olson & Bear LLP

20090263910 - Method for measuring hypochlorite ion: t

20090263911 - End point detection method , end point detection device, and gas phase reaction processing apparatus equipped with end point detection device: An end point detection method in the case where a catalyst 9 arranged in a treatment chamber is heated at high temperature by supplying electric power thereto and the treatment is carried out by cracking a reaction gas by the catalyst 9 heated at high temperature, comprises the steps of... Agent: Carrier Blackman And Associates

20090263913 - Differentially encoded biological analyzer planar array apparatus and methods: A method of probing a plurality of analyzer molecules distributed about a detection platform is disclosed. The method includes contacting a test sample to the plurality of analyzer molecules, scanning the plurality of analyzer molecules at a rate relating to a carrier frequency signal, and detecting the presence or absence... Agent: Bose Mckinney & Evans LLP

20090263912 - Nanowires and nanoribbons as subwavelength optical waveguides and their use as components in photonic circuits and devices: A microfluidic optical sensor utilizes at least one subwavelength nanowire or nanoribbon waveguide coupled to a fluidic structure having at least one nanofluidic channel through which one or more molecular species are conveyed. In response to optical pumping (e.g., a laser source) the waveguide optically interrogates nearby molecular species retained... Agent: John P. O'banion O'banion & Ritchey LLP

20090263915 - Agglutination inhibition assay method and reagent: Provided are an agglutination-inhibition assay and a reagent for agglutination-inhibition assay, which can be used for measuring a ligand in a sample at high sensitivity in a wide range from the low-concentration range to the high-concentration range and have good reproducibility of measurement. Specifically, provided are an agglutination-inhibition assay and... Agent: Greenblum & Bernstein, P.L.C

20090263916 - Antagonists of hmg1 for treating inflammatory conditions: There is disclosed a pharmaceutical composition and method for treating sepsis, including septic shock and ARDS (acute respiratory distress syndrome), comprising administering an effective amount of a HMG 1 antagonist. There is further disclosed a diagnostic method for monitoring the severity or potential lethality of sepsis or septic shock, comprising... Agent: Hamilton, Brook, Smith & Reynolds, P.C.

20090263914 - Bioanalytical assay: A nanoparticle having a detectible feature and whose diameter is less than 200 nm, and which is coated with multiple specific binding reactants such that the affinity constant of the nanoparticle towards an analyte exceeds that of free binding reactant towards the analyte and/or the association rate constant between the... Agent: James C. Lydon

20090263917 - Method for the quality control of molecules or targets: The invention relates to a method for quality control of species used in analytical or diagnostic or therapeutic procedures. It comprises immobilization of a model of the malignancy to a solid support (121), contacting the solid support with species dissolved in liquid (122), measuring both the rate of formation of... Agent: Frishauf, Holtz, Goodman & Chick, PC

20090258427 - Method and reagent mixture for the visualization of amino acids and peptides: The invention relates to a method and reagent mixture for the staining and thus visualisation of amino acids, peptides and similar compounds, in particular after separation by means of thin-layer chromatography. The staining is carried out using NIN-HYDRIN for the detection of amino acids, peptides or proteins in combination with... Agent: Millen, White, Zelano & Branigan, P.C.

20090258426 - Preferred segments of neural thread protein and method of using the same: The invention is directed to preferred repeat sequences of Neural Thread Protein (NTP), peptides, mimetics, antibodies, and nucleic acids of the preferred sequences, and diagnostic and therapeutic methods of using such preferred NTP sequences.... Agent: Foley And Lardner LLP Suite 500

20090258428 - Method for analyzing low molecular weight compound in sample containing water-soluble polymer and low molecular weight compound: The invention relates to an analysis method which can conduct analysis on low molecular weight compound in a sample containing water-soluble polymer and low molecular weight compound under isocratic conditions without being affected by proteins or the like and in which water-soluble polymer and low molecular weight compound can be... Agent: Sughrue Mion, PLLC

20090258429 - Colorimetric detection of cyanide with a chromogenic oxazine: wherein R1 is an alkyl (e.g., methyl, ethyl, propyl, isopropyl, butyl, isobutyl), a substituted alkyl, a cycloalkyl (e.g., cyclopentyl, cyclohexyl), a substituted cycloalkyl, an aryl (e.g., phenyl), or a substituted aryl and R2 is a chromophore (e.g., nitroso, nitro, azo dyes). This quantitative chromogenic transformation permits the detection of micromolar... Agent: Nixon & Vanderhye, PC

20090258431 - Device and method for pressure and flow control in parallel reactors: According to one embodiment, the device according to the invention for the parallel study of chemical reactions comprises at least the following components: (a) at least two spatially separated reaction spaces; (b) on the reaction space input side, at least one common educt feed for the reaction spaces according to... Agent: Choate, Hall & Stewart LLP

20090258430 - Method for identifying electrophiles and nucleophiles in a sample: A method and device for identifying a molecule in a sample, the molecule comprising an electrophilic or nucleophilic moiety. The method comprises contacting the sample with a plurality of chemosensors, each of the chemosensors comprising a π-conjugated system and a moiety having a nucleophilic property or an electrophilic property; and... Agent: Martin D. Moynihan D/b/a Prtsi, Inc.

20090258433 - Abnormality-identifying method and analyzer: Provided is an abnormality-identifying method for identifying an abnormality of an analyzer which analyzes a specimen based on optical characteristics. All predetermined analysis processes to be performed on the specimen but an analysis process whose abnormality is to be examined are eliminated, and the abnormality of the analyzer is identified... Agent: Scully Scott Murphy & Presser, PC

20090258432 - Composition and method: A fire-stop product comprising a characterising marker, wherein the presence of said characterising marker can be detected by a diagnostic method at the site where the product is located.... Agent: Nixon & Vanderhye, PC

20090258435 - Biotin-receptor reagents for sensitivity modulation in assays: Methods are disclosed for designing an antibody reagent for use in an assay for the detection of an analyte to obtain an optimum assay sensitivity and/or dynamic range. The antibody reagent is a conjugate of a small molecule attached by a spacer group to an antibody for the analyte. The... Agent: Dade Behring Inc. Law And Patents

20090258437 - Compounds and methods for rapid labeling of n-glycans: The present invention provides compounds and methods for rapid labeling of N-glycans, for example, rapid fluorescent labeling of N-glycans. In one aspect, the present invention provides fluorescent carbamate or thiocarbamate compounds. Upon contacting with N-glycans, the compounds undergo facile reactions with N-glycans to form fluorescent-labeled N-glycans.... Agent: Townsend And Townsend And Crew, LLP

20090258434 - Fluorescent probe for peroxynitrite: provided that the combination of the aforementioned substituents is such a combination that the compound represented by the formula (I) can be substantially non-fluorescent before reacting with peroxynitrite, and the compound represented by the formula (I) in which the group represented by the formula (A) is nitrated after reacting with... Agent: Greenblum & Bernstein, P.L.C

20090258438 - Method for universal biodetection of antigens and biomolecules: A universal signal molecule is generated in response to the presence within a biological fluid sample of a target agent. Two probes that bind to the target agent are provided within the sample and the target agent is captured, purified, and concentrated on a bead. One of the probes is... Agent: Howard Eisenberg, Esq.

20090258436 - Reagents for the detection of protein phosphorylation in signaling pathways: The invention discloses novel phosphorylation sites identified in signal transduction proteins and pathways, and provides phosphorylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these phosphorylated sites/proteins, as well as methods of using the reagents for such purpose. Among the phosphorylation sites identified... Agent: Nancy Chiu Wilker, Ph.d. Chief Intellectual Property Counsel

20090258439 - Immunochromatoassay method and immunochromatoassay kit: An immunochromatoassay method that allows high detection sensitivity measurement. The method including the steps of: permeating an analyte solution that includes a visibly labeled second binding substance that specifically binds to a detection target substance into a test area of a chromatography medium provided with a first binding substance that... Agent: Sughrue Mion, PLLC

20090258441 - Method of providing particles having biological-binding areas for biological applications: The present invention includes micro-sphere composition, methods of making binding assays. The present invention also includes a micro-sphere for binding biological molecules without pretreatment. The micro-sphere includes a spherical glass substrate having one or more metal nanoparticle regions that are exposed from within the glass, wherein the micro-sphere is capable... Agent: Chalker Flores, LLP

20090258440 - Surface for label independent detection and method thereof: A functional group and spacer group modified polymer composition, articles incorporating the composition, and methods for label-independent-detection using the articles, as defined herein.... Agent: Corning Incorporated

20090258442 - Reagents for the detection of protein phosphorylation in carcinoma signaling pathways: The invention discloses nearly 474 novel phosphorylation sites identified in signal transduction proteins and pathways underlying human carcinoma, and provides phosphorylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these phosphorylated sites/proteins, as well as methods of using the reagents for such purpose.... Agent: Nancy Chiu Wilker, Ph.d. Chief Intellectual Property Counsel

20090253209 - Method of obtaining bzm purity, quantity of [123i]ibzm labeled ligand and quantity of bzm free ligand: A purity of BZM is analyzed by a high performance liquid Chromatography (HPLC) to know whether the purity is qualified. And a quantity of a labeled ligand ([123I] IBZM) and a quantity of a free ligand (BZM) are analyzed by a liquid chromatograph tandem mass spectrometer (LC-MS/MS). The analysis result... Agent: Troxell Law Office PLLC

20090253210 - Differential hemolysis of a whole blood sample: The invention relates to a method for differentially hemolyzing whole blood. It discloses method for detecting an analyte in a liquid sample known or suspected to comprise red blood cells and suspected or known to comprise eukaryotic cells, the method comprising the steps of processing said liquid sample with a... Agent: Roche Diagnostics Operations Inc.

20090253211 - Semiconductor nanocrystal probes for biological applications and process for making and using such probes: A semiconductor nanocrystal compound and probe are described. The compound is capable of linking to one or more affinity molecules. The compound comprises (1) one or more semiconductor nanocrystals capable of, in response to exposure to a first energy, providing a second energy, and (2) one or more linking agents,... Agent: Bozicevic, Field & Francis LLP

20090253212 - Method of determining the effectiveness of water purification: Prospective invention concerns to area of ecology and analytical chemistry, and also to water treatment, and can be used for estimation the effectiveness of water purification from different origin on water intakes with various stages of technological processing, for assessment of overall performance of filters and water treating devices of... Agent: Houston Eliseeva

20090253213 - Device and process for the chromatographic detection of a substance: A device for the chromatographic detection of a substance provides an improved reproducible measuring process. A monitoring indicator (6) is provided, which is designed to detect the relative position of a test strip (13) in relation to the direction of the force of gravity, wherein a processor unit (8) generates... Agent: Mcglew & Tuttle, PC

20090253214 - Method of optical detection of binding of a material component to a sensor substance due to a biological, chemical or physical interaction and apparatus for its embodiment (variants): Application: detection of binding of biological and/or chemical components of liquid or gaseous mixtures and solutions, which are of mainly biological origin and/or determine parameters of living activity of biological objects, to substances that bind the said components due to a biological, chemical or physical interaction; and analysis of mixtures... Agent: Ladas & Parry LLP

20090253215 - Method for controlling the flow of liquids containing biological material by inducing electro- or magneto-rheological effect: The invention provides a method for controlling or manipulating the flow of a solution or liquid comprising biological material or biomolecules. Therefore, particles are added to the solution or liquid for providing the solution or liquid with rheological properties. The solution or liquid comprising the particles is provided in a... Agent: Philips Intellectual Property & Standards

20090253216 - Delivery and sensing of metered amounts of liquid materials: A liquid delivery apparatus is provided for depositing liquid materials onto prescribed areas. The apparatus includes a sensing and delivery pin and a photo sensor. The apparatus is sized to deliver a droplet of liquid material to the surface of a target area without coming into contact with the target... Agent: Mccarter & English, LLP Newark

20090253218 - Method for serologic agglutination and other immunoassays performed in a thin film fluid sample: A method and system for performing a serological agglutination assay in a liquid sample. The system provides a simple method for creating an in-situ sample/reagent admixture within a sample analysis chamber without the use of any precision fluid-handling components.... Agent: O''shea Getz P.C.

20090253217 - Method of quickly detecting antigen using fluorescence correlation spectroscopy or fluorescence cross-correlation spectroscopy: The present invention is to provide a method of quickly detecting an antigen at an arbitrary concentration in an antigen sample, without a multi-stage examination of the concentration ratio between a detection reagent and an antigen to be detected, particularly when the concentration of the antigen in the sample is... Agent: King & Spalding

20090253219 - Positive detection lateral-flow apparatus and method for small and large analytes: Methods and devices for the detection and/or quantification of an analyte in a sample are provided. These are positive detection methods and devices, in that the more analyte is present in the sample, the stronger the signal that is provided. Devices of the invention include a mobilization zone including a... Agent: Klarquist Sparkman, LLP

20090253220 - Absorbing biomolecules into gel-shell beads: Disclosed are ionic gel-coated beads (including Hydrogel™-coated beads), which are capable of adsorbing, or absorbing, proteins and other biomolecules onto or into the gel coating. The gel-coated beads with absorbed or adsorbed biomolecules are suitable for use in an assays, purification or other purposes. The beads have a core made... Agent: Eric P. Mirabel