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Chemistry: analytical and immunological testing May archived by USPTO category 05/12

20120135527 - Material, system, and method that provide indication of a breach: A multilayer material is described herein that includes a flexible inner layer and a flexible outer layer configured to enclose at least one signaling layer, the at least one signaling layer including at least one chemical compound. The multilayer material including the chemical compound within the at least one signaling... Agent: Searete LLC, A Limited Liability Corporation Of The State Of Delaware

20120135528 - Paint for detection of radiological or chemical agents: A paint that warns of radiological or chemical substances comprising a paint operatively connected to the surface, an indicator material carried by the paint that provides an indication of the radiological or chemical substances, and a thermo-activation material carried by the paint. In one embodiment, a method of warning of... Agent: Lawrence Livermore National Security, LLC

20120135529 - Detection of occult blood in feces or urine: The present invention relates to an improved method, reagents and kit for the detection of fecal or urine occult blood. The reagents are either supplied as solutions in small vials or incorporated into a matrix that is treated, impregnated, or imprinted with the test reagents that are capable of undergoing... Agent:

20120135530 - Detection of target analytes using particles and electrodes: The invention relates to the use of particles comprising binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter composition are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence or absence of the target analyte... Agent: Clinical Micro Sensors, Inc.

20120135531 - Sensors for detecting substances indicative of stroke, ischemia, infection or inflammation: A system is disclosed that extracts bodily fluid to a reaction chamber for monitoring a substance or property of the patient fluid. In one embodiment, a pump is used to advance the sample of bodily fluid through a filter to produce a filtrate. Another pump advances filtrate into the reaction... Agent:

20120135532 - Sensor comprising resrufin levulinate having sulfite ion selectivity and method for monitoring sulfite ion using the same: The present invention relates to a sensor comprising a resorufin compound having sulfite ion selectivity and a method for detecting sulfite ions using the same. More specifically, the resorufin compound may have outstandingly increased fluorescence intensity by a deprotection reaction that a levulinyl group is cleaved with a sulfite ion... Agent: Chung-ang University Industry-academiy Cooperation Foundation

20120135533 - Chemical analytic apparatus and chemical analytic method: A chemical analytic apparatus of the present invention is the one which proposes that a miniaturization, a making low-cost and portability are possible and also the operation of each process of separation, concentration and dilution of specimen is possible, and, which includes: an introduction means (S1) that introduces a droplet... Agent: Japan Science And Technology Agency

20120135534 - Adsorption test method of spherical carbon adsorbent: The present invention relates to an adsorption test method of a spherical carbon adsorbent, particularly Kremezin, which includes evaluating a test solution containing one or more kinds of particular uremic toxins or related compounds for the adsorbability, namely, adsorption titer, adsorption speed and/or adsorption selectivity, of the spherical carbon adsorbent.... Agent: Mitsubishi Tanabe Pharma Corporation

20120135535 - Automated real-time particle characterization and three-dimensional velocimetry with holographic video microscopy: An in-line holographic microscope can be used to analyze on a frame-by-frame basis a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. Through a combination of applying a combination of Lorenz-Mie... Agent: New York University

20120135536 - Method and apparatus for detecting and quantifying a chemical substance employing an optical transmission property of metallic islands on a transparent substrate: A sensor for use in detecting and analyzing predetermined chemical substances is presented. The sensor comprises: a first structure configured for binding to a certain substance and comprising a substantially transparent substrate with respect to electromagnetic radiation of a predetermined wavelength range and a plurality of metallic islands deposited onto... Agent: Yeda Research & Development Co., Ltd.

20120135537 - Detection of a component of interest with an ultraviolet laser and method of using the same: Means and method for analysis of a component of interest in a sample is provided. A small sample cell is provided which decreased dispersion of the sample. Also provided is a device for detection of a component of interest in a sample in which the small sample cell is used... Agent: Arkansas State University Research And Development Institute

20120135538 - Agent and method for identifying lysine crotonylation in proteins: A method and related agent for detecting novel post-translational modification. This novel post-translational modification is in the form of crotonylation of lysine residues in proteins. The method includes the steps of (a) preparing a mixture of polypeptides from a protein sample; (b) separating the polypeptides by molecular weight; (c) contacting... Agent:

20120135540 - Methods and compositions of nucleic acid ligands for detection of clinical analytes related to human health: Specific DNA sequences for binding various clinically relevant analytes from the human body are described. Each of these sequences or their linear, two- and three-dimensional linked sequences can function in varying assay and sensor formats with varying degrees of success. Linkage of the whole or partial DNA sequences (putative binding... Agent: Otc Biotechnologies, LLC

20120135542 - Methods and materials for diagnosing light chain amyloidosis: This document relates to methods and materials involved in diagnosing light chain amyloidosis. For example, methods and materials for using exosomes to diagnose a mammal (e.g., a human) as having immunoglobulin light chain amyloidosis are provided.... Agent: Mayo Foundation For Medical Education And Research

20120135541 - Multi-directional microfluidic devices comprising a pan-capture binding region and methods of using the same: Microfluidic devices and methods for using the same are provided. Aspects of the invention include microfluidic devices that include a separation medium and a pan-capture binding medium. The microfluidic devices are configured to subject a sample to two or more directionally distinct electric fields. Also provided are methods of using... Agent:

20120135539 - Split dna enzyme for visual single nucleotide polymorphism typing: A probe that changes solution color in the presence of only one of the two DNA sequences, which differ by a single nucleotide, is reported. The probe consists of two oligodeoxyribonucleotides, which form a hydrogen peroxidase-like DNA enzyme when hybridized to the abutting fragments of the complementary analyte. The active... Agent: The Trustees Of Columbia University In The City Of New York

20120129265 - New biomarkers for assessing kidney diseases: The present invention relates to a metabolic biomarker set for assessing kidney disease comprising at least two amino acids, at least two acylcarnitines and at least two biogenic amines. Moreover, the present invention relates to a method for assessing kidney disease in a mammalian subject which comprises obtaining a biological... Agent: Biocrates Life Sciences Ag

20120129266 - Method of detecting oxides of nitrogen: The present disclosure provides methods and kits to detect and quantitate NOx compounds in a biological sample. The methods include reacting a mixture comprising a nitrite compound a chromogenic reagent to form a colored compound, contacting the mixture with a retention medium configured to retain the colored compound, and detecting... Agent:

20120129267 - Sulfur breakthrough detection assembly for use in a fuel utilization system and sulfur breakthrough detection method: A sulfur breakthrough monitoring assembly for use in a fuel utilization system for detecting sulfur-containing compounds in desulfurized fuel, said monitoring assembly comprising: a heater for heating desulfurized fuel to a predetermined temperature, the predetermined temperature being between 450° C. and 600° C., a sulfur breakthrough detector adapted to receive... Agent: Fuelcell Energy, Inc.

20120129268 - Photoluminescent oxygen probe with reduced cross-sensitivity to humidity: An oxygen-sensitive luminescent element, and probe constructed therefrom, having reduced cross-sensitivity to humidity, and methods of manufacturing and using such luminescent elements and probes to measure oxygen concentrations within an enclosed space. The luminescent element includes a glass fiber carrier substrate bearing an oxygen-sensitive photoluminescent dye. The dye is preferably... Agent:

20120129269 - Nano-optic filter array based sensor: A device such as a filter or reflector includes a conductive layer including a periodic pattern of elements. The elements have shapes and sizes configured such that a transmittance or reflectance spectrum of the conductive layer has a drop at a long-wavelength end. The elements have a period configured such... Agent: Nanolambda, Inc.

20120129270 - Vesicular system and uses thereof: Disclosed is a vesicular system comprising a surface with a vesicle immobilized thereon. The immobilized vesicle has a circumferential membrane of an amphiphilic polymer. The vesicle is coupled to a surface by means of a molecule with a non-polar moiety. The non-polar moiety comprises a main chain of 3 to... Agent:

20120129271 - Longitudinal assay: Embodiments of the invention relate generally to macro and small molecule detection and, more particularly, to methods for detecting macro and small molecules, including bio-molecules, in a liquid or gaseous sample. Methods according to embodiments of the invention are useful in the identification, discovery, and validation of biomarkers, as well... Agent: Inanovate, Inc.

20120129272 - Lateral flow assay systems and methods: In one aspect, a diagnostic test system includes a housing, a reader, and a data analyzer. The housing includes a port for receiving a test strip. The reader obtains separable light intensity measurements from localized regions of an area of the detection zone exposed for optical inspection, wherein each of... Agent: Alverix, Inc.

20120122226 - Apparatus and method for indicating biological content within a container: An apparatus for indicating biological content within a container is provided. The apparatus includes a medical sterilization container having a cover removably attached to the medical sterilization container. An enclosable, sterilizable interior compartment is formed by the medical sterilization container and the cover, wherein the interior compartment is sized to... Agent: Symmetry Medical Manufacturing, Inc.

20120122227 - Guided structured testing kit: A guided structured testing kit comprising a test strip container, a test strip meter, a testing protocol advisor, and at least one of diagnostic test strip is presented. The diagnostic test strip comprising a support element, a glucose reagent provided on the support element, and a glycemic context code provided... Agent: Roche Diagnostics Operations, Inc.

20120122228 - Compositions and methods for the detection of chemical warfare agents: Compositions for detection of chemical warfare agents that comprise oximate anion reactive sites and fluorophore cores. Methods for detecting a chemical warfare agents that comprise providing a detector molecule comprising an oximate anion reactive site and a fluorophore core and detecting fluorescence from the detector molecule. Methods for enhancing the... Agent:

20120122229 - Methods of assaying for tetrahydrocannabinol: The invention provides a method of assaying for tetrahydrocannabinol in a body fluid, said method comprising contacting a sample of body fluid with an imine capable of reacting with tetrahydrocannabinol to yield a quinone imine, and detecting the formation of a quinone imine, characterised in that said sample is contacted... Agent: Oxtox Limited

20120122230 - Methods for identifying high fouling hydrocarbon and for mitigating fouling of process equipment: Methods for determining the fouling propensity of a hydrocarbon stream and for reducing fouling are provided. In one method, the fouling propensity of a hydrocarbon stream is determined by obtaining a parameter value indicative of the fouling propensity at no less than two different temperatures, and an activation energy of... Agent: Exxonmobil Research And Engineering Company

20120122231 - Specimen testing device and method thereof: The present invention relates to a specimen testing device and method thereof, and it is an object of the present invention to provide a compact and reliable specimen testing device and method thereof. The specimen testing device includes one, two or more test cartridge containers which comprise a plurality of... Agent: Universal Bio Research Oco., Ltd.

20120122232 - Cassette for sample preparation: A cassette for preparing a sample is disclosed herein. The cassette includes a housing, which encloses the structures and the processes used to prepare the sample.... Agent: Genturadx, Inc.

20120122245 - Alloyed metal colloid: Provided is a metal colloid having higher visibility and higher sensitivity than a gold colloid and a Au-core Pt-shell composite colloid and suitable as a labeling agent for use in a test such as an immunoassay. An alloyed Au/Pt composite colloid formed by mixing a gold salt and a platinum... Agent: Kogakuin University

20120122240 - Bioassays using plasmonic scattering from noble metal nanostructures: The present invention relates to detecting and/or measuring scattering effects due to the aggregating metallic nanostructures or the interaction of plasmonic emissions from approaching metallic nanoparticles. The scattering effects may be measured at different angles, different wavelengths, changes in absorption and/or changes in polarization relative to changes in the distances... Agent:

20120122235 - Devices and methods for detection of biomolecular interactions: Devices, systems, and methods are provided for the detection of biomolecular interactions. The interactions between one or more target DNA strands, one or more receptor DNA strands, and one or more probe DNA strands, if necessary, are used to detect the one or more target DNA strands. The one or... Agent: Florida State University Research Foundation, Inc.

20120122234 - Fluidic indicator device: Disclosed is a fluidic assay device for assaying at least one property of a liquid sample comprising: a liquid sample application region; at least one test flow path in liquid flow communication with the sample application region; a reference flow path in liquid flow communication with the sample application region;... Agent:

20120122237 - Homogeneous noncompetitive detection of post translational modifications for use in high throughput assays: The use of a secondary binding molecule will increase the sensitivity and selectivity of antigen detection compared to use of the primary antibody alone. The use of a secondary binding molecule also allows direct, homogenous detection rather than competition with a labeled tracer, because the secondary binding molecule can be... Agent:

20120122239 - Human nt-pro b-type natriuretic peptide assay having reduced cross-reactivity with other peptide forms: The present disclosure relates to assays for detecting and/or quantifying the amount of human NT-pro B-type natriuretic peptide or human NT-pro B-type natriuretic peptide fragment in a test sample.... Agent: Abbott Laboratories

20120122241 - Identification and monitoring of systemic lupus erythematosus: A method for identifying or monitoring SLE in an individual is provided. The method includes quantitating complement component C4d on the surfaces of platelets and comparing the amounts of C4d to reference levels of C4d on platelets of individuals without SLE and/or on platelets of the individual obtained at a... Agent: University Of Pittsburgh - Of The Commonwealth System Of Higher Education

20120122243 - Means and method and means for diagnosing prostate carcinomas: The present invention relates to a method, preferably an ex vivo method, for diagnosing prostate carcinomas and/or predisposition thereof comprising determining at least one metabolite in a test sample of a subject suspected to suffer from prostate carcinomas or to have a predisposition therefor and comparing said at least one... Agent: Metanomics Health Gmbh

20120122236 - Method and system utilizing lateral flow immunoassay test device with integrated quality assurance label: The present invention provides a method and system for performing analyte analysis with improved reliability of test results through use of quality assurance labels for accuracy and robust results.... Agent:

20120122242 - Method for assessing arteriosclerosis and diabetic nephropathy: A method for assessing arteriosclerosis comprising measuring the serotonin level in whole blood, serum or platelet-rich plasma and rating the serotonin level on such a scale that the lower it is, the more serious the arteriosclerosis is.... Agent: Tosoh Corpopration

20120122233 - Method for risk stratification in stable coronary artery disease: An in vitro method for the risk stratification of patients with stable arteriosclerosis, especially stable coronary artery disease, is disclosed wherein the concentration of procalcitonin is determined in the circulation of such patients using a highly sensitive PCT assay, and wherein within the range of PCT concentrations in the typical... Agent: B.r.a.h.m.s Aktiengesellschaft

20120122244 - Method of identifying compounds that inhibit fertilization: A method of identifying compounds that inhibit fertilization is provided. The method can include selecting compounds that bind to equatorin protein. Two types of equatorin protein, a long form and a short form, can be present in the testis. The amino acid sequence of mouse equatorin from positions 101 to... Agent: National University Corporation Chiba University

20120122238 - Vmp-like sequences of pathogenic borrelia: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borreliae, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis.... Agent:

20120115236 - Device and method for indirect electronic condition control in biomolecule detection platforms: A system and method of indirectly modifying an environmental condition at a test site in one embodiment includes providing a test site on a substrate, providing a hydrogel composition loaded with a chemical factor at the test site, providing an actuator configured to activate the hydrogel composition to release a... Agent: Robert Bosch Gmbh

20120115237 - Isolation of rna-protein complexes using cross-linking reagents and oligonucleotides: Provided herein is a method of sample analysis. In certain embodiments, the method comprises: a) cross-linking protein of a cell using a first compound to produce a first cross-linked product comprising cross-linked protein, and RNA; b) contacting the first cross-linked product and a second compound under conditions by which an... Agent:

20120115238 - Nucleic acid extraction kit, nucleic acid extraction method, and nucleic acid extraction apparatus: A nucleic acid extraction kit, which enables the nucleic acid extraction operation to be accomplished safely without causing contamination, and in which the complex preparation of reagents and the disposal treatments that are performed before and after the nucleic acid extraction operation can be performed rapidly and simply, with the... Agent: Toppan Printing Co., Ltd.

20120115239 - Vapochromic coordination polymers for use in analyte detection: Vapochromic coordination polymers useful for analyte detection are provided. The vapochromism may be observed by visible color changes, changes in luminescence, and/or spectroscopic changes in the infrared (IR) signature. One or more of the above chromatic changes may be relied upon to identify a specific analyte, such as a volatile... Agent: Simon Fraser University

20120115240 - Treatment of ruminant exhalations: Methane gas in a ruminant exhalation may be oxidized to reduce the amount of methane gas output by the ruminant.... Agent: Searete LLC, A Limited Liability Corporation Of The State Of Delaware

20120115241 - Systems, devices, and methods for remotely interrogated chemosensor electronics: Systems, devices and methods for remotely interrogating sensor electronics are described. In one embodiment, a system for detecting and localizing chemical analytes is described. This system includes a plurality of chemosensor electronic devices for detecting the presence of chemical analytes. Each of these devices includes a chemosensor for sensing chemical... Agent: Raytheon Bbn Technologies Corp.

20120115242 - Vitamin d metabolite determination utilizing mass spectrometry following derivatization: The invention relates to the detection of vitamin D metabolites. In a particular aspect, the invention relates to methods for detecting derivatized vitamin D metabolites by mass spectrometry.... Agent: Quest Diagnostics Investments Incorporated

20120115243 - Sample port, multi-layer filter, sampling method, and use of a sample port in sampling: The invention relates to a sample port, filter, and sampling method. The sample port according to the invention comprises a body equipped with an internal cavity and two plungers arranged moveably in this, which can be pressed against each other in the internal cavity, in order to compress a sample,... Agent: Teknologian Tutkimuskeskus Vtt

20120115245 - Assaying substrate with surface-enhanced raman scattering activity: A metal substrate obtained by agglomerating 5 nm to 100 nm metal nano-particles (including clusters) having SERS activity on a metal substrate having a lower electrode potential (higher ionization tendency) than the electrode potential of the metal nano-particles, and fixing the metal nano-particles in an optimally agglomerated state that acts... Agent:

20120115249 - Biomarker for selecting patients and related methods: The present invention concerns biomarkers and use thereof for determining whether a subject is or is not susceptible to developing a prophylactic or therapeutic immune response after such treatment.... Agent:

20120115247 - Drug monitoring assay: A method for obtaining at least one binding agent which binds a pharmaceutically active form of the compound with a higher specificity than a pharmaceutically inactive form of the compound is described by using special derivatives of said parent compound. The invention also pertains to the respectively created binding agents... Agent:

20120115244 - Materials and methods for immunoassay of pterins: Methods of assaying for (i) a pterin by immunoassay employing a pterin as capture agent, (ii) neopterin by chemiluminescent microparticle immunoassay (CMIA) employing an anti-neopterin antibody (Ab) as capture agent, (iii) neopterin by an immunoassay (IA) employing an acridinium (Acr)-labeled anti-neopterin Ab as conjugate, and (iv) neopterin by an IA... Agent: Abbott Laboratories

20120115248 - Methods of determining the presence and/or concentration of an analyte in a sample: Compositions, methods, and systems for monitoring analyte levels are provided herein. The disclosure provides methods and systems for the real-time monitoring of analytes, such as citrate, calcium, phosphate and magnesium, in a biological fluid in a clinical setting.... Agent:

20120115246 - Microfluidic device comprising sensor: The invention relates to a microfluidic device for performing detection of a substance in a liquid sample, wherein a cavity (24) is formed above a sensor surface area (22) of a sensor (18), said cavity (24) extending at the first side of a base plate (10) from a first area... Agent: Koninklijke Philips Electronics N.v.

20120107940 - Methods for analyzing polar metabolites of the energy metabolism: The present invention is concerned with the analysis of polar metabolites and provides methods for analyzing polar metabolites comprising extracting a biological sample with a ex-traction buffer comprising a phase separator and a volatile neutral ammonium salt under conditions which allow for immediate disruption of cells comprised by the biological... Agent: Basf Plant Science Company Gmbh

20120107941 - Real-time monitor solid phase peptide synthesis by mass spectrometry: Provided are systems, apparatus, materials and methods for directly monitoring products and intermediates of solid phase chemical synthesis such as solid phase peptide synthesis.... Agent: National Sun Yat-sen University

20120107942 - Compounds and methods for rapid labeling of n-glycans: The present invention provides compounds and methods for rapid labeling of N-glycans, for example, rapid fluorescent labeling of N-glycans. In one aspect, the present invention provides fluorescent carbamate or thiocarbamate compounds. Upon contacting with N-glycans, the compounds undergo facile reactions with N-glycans to form fluorescent-labeled N-glycans.... Agent: Prozyme, Inc.

20120107943 - Labelling strategies for the sensitive detection of analytes: The present invention relates to methods and reagents for detecting analytes, e.g. nucleic acids. The new methods and reagents allow a simple and sensitive detection even in complex biological samples.... Agent: Baseclick Gmbh

20120107944 - Holographic sensor: Y is a spacer which, when n is 0 or otherwise optionally, is an atom or group which, via an electronic effect, promotes formation of a tetrahedral geometry about the boron atom. Such a sensor may be used for the detection of glucose.... Agent:

20120107945 - Chemical reagent for measuring the level of halogen agents, in particular in swimming-pool water and associated measurement method: The present invention relates to a chemical reagent for measuring the halogen-agent content, in particular in swimming pool water, and also to an associated measurement method, and such that the chemical reagent, according to the invention, comprises a polysaccharide, an acid stabilizer compound, potassium iodide, a dye, and distilled water.... Agent: Pacific Industrie

20120107946 - Detection of explosives and other species: The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant,... Agent: Nomadics, Inc.

20120107947 - Total organic carbon measuring instrument: A total organic carbon measuring instrument including a measuring unit composed of, integrated together, organic substance oxidation part and carbon dioxide separation part and conductivity measuring part, control unit and data processing unit. In order to enhance the accuracy of conductivity measurement, the control unit is constructed so as to... Agent: Shimadzu Corporation

20120107948 - Luminescent chemical sensor integrated with at least one molecular trap: A luminescent chemical sensor integrated with at least one molecular trap. The luminescent chemical sensor includes at least one molecular trap and at least one metallic-nanofinger device integrated with at least one molecular trap. The molecular trap includes a plurality of electrodes that trap at least one analyte molecule. The... Agent:

20120107949 - Test swipe for portable explosive or drug detection system: A portable chemical analytical apparatus to analyze a test swipe having a base; a chemically treated pad containing the swiped sample positioned in a white zone above the base; and a tab attached to one side of the base. The apparatus includes a heater to warm the test swipe to... Agent:

20120107950 - Measurement system for fluorescent detection, and method therefor: In one aspect, the invention provides a measurement system, wherein the measurement system comprises a sample module to receive a sample, wherein the sample module comprises at least one fluorophore; an optics module to generate an incident beam to impinge on the sample to yield a laser spot; a detector... Agent:

20120107951 - Apparatus for punching and solid phase extraction of dried biological fluid spot and related methods: An apparatus for punching and extracting analytes from a dried biological fluid spot includes a tube and a sorbent bed. The tube includes a proximal tube opening, a distal tube opening, and a distal section. The distal section includes a tube wall having a tapered diameter that reduces down to... Agent:

20120107959 - Bait chemistries in hydrogel particles for serum biomarker analysis: This invention describes the identification of novel organic dye chemistries that can be used as affinity baits to capture proteins and other biomolecules useful in the fields of medical diagnostics, environmental science, toxicology, and infectious disease. Incorporation of unique affinity dye compounds within hydrogel capture particles improves analyte yield and... Agent:

20120107956 - Indirect lateral flow sandwich assay: Disclosed herein are indirect lateral flow sandwich assays, in which the target analyte binds an analyte-specific reagent comprising a first member of a conjugate pair, forming a complex which contacts and binds a colored particulate label comprising a complementary member of said conjugate pair, forming a second complex. Capture of... Agent:

20120107961 - Magnetic sensor device, method of operating such a device and sample: A sensor device (1) for detecting the presence of a target molecule (20) in a sample, is disclosed. The sensor device comprises a measurement sensor (2) comprising a first moiety (16) for forming a binding couple with a first further moiety comprising the target molecule (20) and a detectable label... Agent: Koninklijke Philips Electronics N.v.

20120107955 - Metabolite biomarkers for the detection of esophageal cancer using ms: Results of studies of nucleosides in biofluid specimens from patients with esophageal adenocarcinoma and related disorders have identified five biomarkers of the conditions: 1-methyladenosine, N2,N2-dimethylguanosine, N2-methylguanosine, cytidine and uridine. In certain embodiments, methods of measuring these biomarkers and kits for measuring these biomarkers are provided.... Agent: Purdue Research Foundation

20120107958 - Microbead optical sensor with layered plasmon structure for enhanced detection of chemical groups by sers: An optical sensor and method for use with a visible-light laser excitation beam and a Raman spectroscopy detector, for detecting the presence chemical groups in an analyte applied to the sensor are disclosed. The sensor includes a substrate, a plasmon resonance mirror formed on a sensor surface of the substrate,... Agent:

20120107952 - Microwave-accelerated plasmonics: The present invention relates to systems and methods using microwave accelerated surface plasmonics for the detection of target species, wherein the system has a metallic surface and the system is exposed to microwave energy for increasing detection time and/or the reaction kinetics of the target species and other interacting participants... Agent: University Of Maryland Biotechnology Institute

20120107960 - Nonlinear luminescent molecule, fluorescent stain, and observation method(as amended): The present invention relates to a nonlinear fluorescent molecule that generates a nonlinear fluorescence reaction by incidence of excitation light. This nonlinear fluorescence molecule includes donors and, and an acceptor that is coupled to the donors and. As the donor is excited by the incidence of the excitation light, electric... Agent: Osaka University

20120107954 - Physiologic sample preparation for nanosensors: The present invention provides a microfluidic purification chip for capturing a biomarker from a physiological solution. The present invention also provides a method of capturing and releasing a biomarker, wherein the biomarker is originally in a physiological solution. The present invention further provides a method of pre-purifying and measuring the... Agent: Yale University

20120107953 - Stabilization of interleukin 6 in serum based solutions: Disclosed is a composition including IL-6, an isoform or a fragment thereof, a compound of the formula C10-C18-alkyl trimethylammonium halogenide (I), wherein the compound is saturated or unsaturated and/or substituted or unsubstituted, or a salt thereof, wherein the concentration of the compound in the composition is about 0.15 to about... Agent:

20120107957 - Test reagent, and method for measuring analyte in test sample using same: Object: To provide a test reagent for the analyte in a test sample, utilizing the level of agglutination of a particle suspension which suspend insoluble carrier particles carrying a substance for capturing the analyte as an indicator, which reagent does not undergo self-agglutination during storage, and which non-specific agglutination rarely... Agent: Denka Seiken Co., Ltd.