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Chemistry: analytical and immunological testing December patent applications/inventions, industry category 12/09

20090325299 - Analyzer and method for aspirating specimen: An analyzer comprising: a specimen container setting portion including a plurality of container holders for holding a plurality of specimen containers of different types; an aspiration section for aspirating the specimen from the specimen container set in the specimen container setting portion; a sensor for detecting the presence of the... Agent: Brinks Hofer Gilson & Lione

20090325300 - Apparatus and method for detection of trace chemicals: A method of rapidly detecting trace materials including biohazards, toxins, radioactive materials, and narcotics in situ is disclosed. A corresponding apparatus is disclosed. A trace of the material is collected on a pad of the card component, collected by swiping the pad on suspected surface or exposure to the suspected... Agent: Harish Dhingra

20090325301 - Modulation of the binding properties of nucleic acid binding partners: A method for specifically determining the presence of a target by contacting the target in the presence of other targets with a probe capable of binding to the target to form a complex of the target with the probe, where the contacting is performed in the presence of a compound... Agent: Robert K. Carpenter

20090325302 - Diagnostic marker for diabetic vascular complications: The present invention relates to the discovery that CTGF is a diagnostic marker indicative of increased risk for development and progression of vascular disease.... Agent: Fibrogen, Inc.

20090325304 - Mammalian disease detection system: A mammalian disease detecting system used to provide a visual indication of a possible disease state includes particles comprised of a material that is substantially clear or transparent to permit the easy visual detection of blood in urine of a mammal. The system also includes additives to permit visually detection... Agent: Chernow Katz, LLC

20090325303 - Process: A method for detecting a presence of an abnormal component in a keratin sample taken from a subject suffering from a pathological state comprising the steps of exposing the keratin sample to a swelling substance so as to penetrate the keratin sample thereby producing a derived chemical substance; obtaining data... Agent: Merchant & Gould PC

20090325305 - Detectable threading intercalator: wherein IG1, IG2, and IG3 are the same or different and represent an intercalating group comprising a planar polyaromatic group; wherein DG represents an electrochemical, a chemiluminescent, a catalytic or an electrochemiluminescent detectable group; and wherein n represents 0 or 1. This invention also relates to a process of detecting... Agent: Klarquist Sparkman, LLP

20090325306 - Fingerprint analysis for a plurality of oligonucleotides: The invention provides a method for evaluating the accuracy of an oligonucleotide sample, specifically a sample containing a variety of oligonucleotides of potentially varying size and sequence. The method provides a fingerprint that can be used to evaluate the accuracy of a multi-oligonucleotide sample whether or not the sample contains... Agent: John Petravich Integrated Dna Technologies, Inc.

20090325307 - Method for manufacturing a strip for use with a multi-input meter: Strips particularly test strips and adapters for test strips, for use in meters for the electrochemical measurement of analyte in a sample material and in particular the glucose concentration of a sample of blood. The strips comprise a plurality of working connectors, for interfacing with the meter, coupled to one... Agent: Philip S. Johnson Johnson & Johnson

20090325308 - Method of detecting residual detergent and device for detecting residual detergent: It is intended to provide a method whereby residual detergent (surfactant) can be conveniently and accurately detected in the step of washing or rinsing dishes or clothes, and a test device usable in examining the rinsed conditions. Namely, a method characterized by comprising bringing a test substance with a composition... Agent: Westerman, Hattori, Daniels & Adrian, LLP

20090325309 - Reagent delivery system, dispensing device and container for a biological staining apparatus: The invention concerns reagent delivery system for an apparatus for processing of biological samples arranged on microscope slides, comprising a reagent section having one or more reagent containers; a slide section in which at least one microscope slide is arranged; a probe for dispensing a portion of reagent onto a... Agent: Dako/finnegan, Henderson, LLP

20090325310 - Innovativer tsh-r-ab-kit: Methods are described for detection of autoimmune antibodies against the TSH receptor using TSH receptor chimeras, which preferably only contain the extracellular portion of the TSH wild type receptor modified as chimera, and are modified by highly immunogenic peptide residues or by enzymes suitable for detection, wherein the determination methods... Agent: Honigman Miller Schwartz & Cohn LLP

20090325315 - Detection method of target substance, detection reagent used for the same, and the uses thereof: A new detection method, for detecting a target substance using formation of an aggregate due to binding of a target substance and a binding substance that binds thereto, that is excellent in detection accuracy, and sensitivity, and a new detection reagent used for the same are provided. Modifying substances having... Agent: Hamre, Schumann, Mueller & Larson, P.C.

20090325311 - Measurement methods: The invention relates to methods for measuring unconjugated molecules, e.g. antibodies, in a mixture that also includes conjugated molecules, e.g. antibodies.... Agent: Lando & Anastasi, LLP

20090325314 - N-methyl scanning mutagenesis: The present invention relates to methods and compositions comprising the insertion of a single N-methyl amino acid into functional peptides. More specifically, the invention discloses methods referred to as N-methyl scanning mutagenesis, where one or more N-methyl amino acid substitutions into functional peptides enhances protease resistance while retaining binding affinity.... Agent: Hogan & Hartson L.L.P.

20090325312 - Reagens for the detection of protein acetylation signaling pathways: The invention discloses 426 novel acetylation sites identified in signal transduction proteins and pathways underlying human protein acetylation signaling pathways, and provides acetylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these acetylated sites/proteins, as well as methods of using the reagents for... Agent: Nancy Chiu Wilker, Ph.d. Chief Intellectual Property Counsel

20090325313 - Two helix binders: An isolated polypeptide, Z domain, derived from B domain of Staphylococcal protein A, comprising a pair of anti-parallel alpha helices that are capable of binding a target, is provided herein. Introduction of an un-natural amino acid in the polypeptide is provided here. Also provided are methods of using the two-helix... Agent: General Electric Company Global Research

20090325316 - Compositions for use as a signal generation component and methods of using same:

20090325317 - Method and system for suppressing bindings on magnetic particles: A method for suppressing non-specific bindings between molecules includes providing magnetic particles dispersed in a liquid, wherein each of the magnetic particles has a magnetization. The magnetic particles are coated with coating molecules. Binding molecules mixed of first-type binding molecules and second-type binding molecules are applied to the liquid, wherein... Agent: J C Patents

20090325318 - Supra nanoparticle assemblies and methods of making and using the assemblies: A method of reporting a binding event having increased sensitivity and multiplex capabilities. A reporter supra-nanoparticle assembly is provided that has an inner core made of a polymeric material, a coating on the inner core made of a polymeric material and a plurality of reporter nanoparticles, and a first active... Agent: Davis, Brown, Koehn, Shors & Roberts, P.C. The Davis Brown Tower

20090317912 - Method of measuring glycated hemoglobin concentration: The present invention relates to a method and an apparatus that measure the concentration of glycated hemoglobin by an optical technique. A wavelength in which the molecular extinction coefficient of oxyhemoglobin agrees or substantially agrees with the molecular extinction coefficient of deoxyhemoglobin is adopted as a measurement wavelength. Preferably, the... Agent: Rader Fishman & Grauer PLLC

20090317913 - Detection of peroxide radicals and reaction initiators: Sensors including a functional component, methods for making such sensors and methods for using sensors including a functional component for the detection of free radical forming compounds including peroxides and devices incorporating such sensors are provided herein.... Agent: Pepper Hamilton LLP

20090317914 - Fluorescent probe: [R1 represents hydrogen atom, or 1 to 4 monovalent substituents; R2, R4, R5, and R7 represent hydrogen atom, or a monovalent substituent; R3 represents ═O or ═N+(R8)(R9).M− (R8 and R9 represent an alkyl group, and M− represents a counter ion); R6 represents —OH or —N(R10)(R11) (R10 and R11 represent an... Agent: Greenblum & Bernstein, P.L.C

20090317915 - Biochip detection device and detection method therof: The present invention provides a biochip detection device and a detection method thereof. The detection device includes a detection circuit and a biochip containing a plurality of sensor modules. Each sensor modules includes a plurality of giant magnetoresistive biosensors. The detection circuit is arranged to have an end of each... Agent: Rosenberg, Klein & Lee

20090317916 - Chemical sample collection and detection device using atmospheric pressure ionization: A chemical sample collection and detection system is disclosed. The chemical sample collection and detection system includes a sample collection device and a detection device. The sample collection device includes a housing having two opposite sides and at least one openings on each side to allow a fluid sample passing... Agent: Andrews Kurth LLP

20090317917 - Biosensor and method for detecting analytes: The present invention concerns in general a biosensor in the form of a microchip for the optical detection of analytes and a method using this biosensor. In particular the invention concerns biosensors for detecting an analyte by time-resolved luminescence measurement and a corresponding method.... Agent: Biotech Beach Law Group , PC

20090317918 - Method of heating liquid medium using microwaves and anions: Provided is a method comprising adding anions having a high charge density to a liquid medium; the liquid medium comprising molecules that hydrogen bond with one another; the anions interacting with the molecules of the liquid medium with a force that is stronger than the forces that produce hydrogen bonding... Agent: Cantor Colburn, LLP

20090317921 - Antibody to inhibin/ activin beta-b subunit: The present invention provides an improved antibody specific for the inhibin/activin beta-B subunit polypeptide. The antibody is highly specific for the beta-B subunit in a sample, and does not require processing of the sample with heat or oxidizing agents. Thus, discovery of the new antibody provides for simpler, more accurate... Agent: Michael C. Schiffer - Legal Dept. Beckman Coulter, Inc.

20090317920 - Hapten compound and antibody: and an antibody to BSH obtained by using the compound as a hapten and using a complex of the hapten and a high-molecular compound as an antigen. By using the present invention, it becomes possible to provide a hapten compound for preparing an antibody recognizing BSH highly sensitively and highly... Agent: Fulbright & Jaworski, LLP

20090317919 - Method for assaying antigens: A method for assaying an antigen adsorbed on a solid support is provided. The method comprises: a) contacting a suspension of the antigen adsorbed on the solid support with a solution or suspension of an optionally detectably-labelled primary antibody to the antigen to form a solid-supported antigen-antibody complex; b) where... Agent: Carella, Byrne, Bain, Gilfillan, Cecchi, Stewart & Olstein

20090317922 - Use of additives to lower the rate of a binding reaction: A method of lowering the rate of a specific binding reaction in an assay for the detection and/or measurement of an analyte of interest is provided herein. In particular, the method includes providing a fluorescent conjugate of the analyte; a component capable of specifically binding to the analyte and its... Agent: Hoffmann & Baron, LLP

20090311794 - Denaturation control: P

20090311792 - Fibroblast growth factor (fgf23) and methods for use: The present invention relates to a kit for diagnosing a disorder comprising a reagent that detects FGF23 polypeptides and mutant FGF23 polypeptides.... Agent: Drinker Biddle & Reath Attn: Intellectual Property Group

20090311793 - Method of esterifying bio-related molecule for mass spectrometry and method of mass spectrometry of obtained esterified derivative: A method of preparing a bio-related molecule to be subjected to mass spectrometry, in which at least a part of acid group(s) is esterified, comprising reacting a bio-related molecule comprising an acid group(s) with a triazene compound to esterify at least a part of said acid group(s). A method of... Agent: Jacobson Holman PLLC

20090311795 - Bilateral control of functions traditionally regulated by only serotonin or only dopamine: Methods of using amino acid precursors of the serotonin and catecholamine neurotransmitter systems and laboratory urinary assay of serotonin and catecholamine neurotransmitter levels for optimal treatment of transporters for neurotransmitters, and or neurotransmitter dysfunction and dysfunction of systems regulated or controlled by the serotonin and/or catecholamine neurotransmitter systems. The methods... Agent: Vidas, Arrett & Steinkraus, P.A.

20090311796 - Microfluidic analytical device for analysis of chemical or biological samples, method and system thereof: An analytical device for analysis of chemical or biological samples, a method of using such a device, based on rotation of the device, integrated sample dosing and optical detection, and a system comprising such a device are disclosed. The analytical device comprises a device body having a liquid processing unit.... Agent: Dinsmore & Shohl, LLP One Dayton Centre

20090311797 - Analysis method and analysis apparatus: An analysis method includes the steps of causing a moist sample to react with a reagent and measuring concentration of a particular component contained in the sample based on the state after the reaction of the sample with the reagent. The reaction step and the measurement step are performed while... Agent: Hamre, Schumann, Mueller & Larson, P.C.

20090311798 - Se(r)rs displacement assay: A detection method is described for detecting an analyte, in particular nucleic acids, in a sample using SE(R)RS, without the need for labeling of the analyte. The detection method is based on the displacement of a labeled surrogate target probe from a capture probe by the analyte in the sample.... Agent: Philips Intellectual Property & Standards

20090311799 - Nucleic acid materials for nonradiative energy transfer and methods of production and use: Nucleic acid materials for FRET-based luminescence and methods of making and using the nucleic acid materials are provided. The nucleic acid materials provide an innovative and synergistic combination of three disparate elements: a nucleic acid material, the processing technique for forming a nucleic acid material into films, fibers, nanofibers, or... Agent: John S. Pratt, Esq Kilpatrick Stockton, LLP

20090311801 - Diagnostic test to exclude significant renal injury: Methods for determining the risk of developing acute renal failure in a human subject by measuring human neutrophil gelatinase-associated lipocalin (NGAL) are provided.... Agent: Licata & Tyrrell P.C.

20090311802 - Isolated soluble il-tif/il-22 receptor or binding protein which binds to il-tif/il-22 and uses thereof: The invention relates to soluble proteins which bind to the molecule known as IL-TIF/IL-22. The proteins can antagonize the effect of IL-TIF/IL-22 on target cells. The nucleic acid molecules encoding the proteins, and uses of the protein, are also described.... Agent: Wyeth/latimer & MayberryIPLaw, LLP

20090311803 - Treatment of tumors expressing mutant egf receptors: The invention discloses methods for identifying antibodies that reduce or prevent signaling by intact epidermal growth factor receptor (EGFR), or mutant EGFRs, such as EGFRvIII.... Agent: Clark & Elbing LLP

20090311800 - Ultrasound method: The present invention provides methods and apparatus for detecting the product of a reaction on a particle held at the pressure node of a standing wave. The methods and apparatus are particularly concerned with blood typing and the Coombs method.... Agent: Nixon & Vanderhye, PC

20090311805 - Assay device and method: There is disclosed an analysis device for the analysis of a liquid sample, said device comprising a substrate, said substrate at least partly having projections substantially vertical to the surface of said substrate, and having a height (H1), diameter (D1) and center-to-center distance (x1, y1) such, that lateral capillary flow... Agent: Morrison & Foerster LLP

20090311804 - Magnetic bead assisted sample conditioning system: A magnetic bead assisted sampling system for a fluid sensor. Magnetic beads are dispersed in a sampling volume for collecting the analyte. The beads are packed into a small volume for pre-concentration of the analyte. A solvent may be applied to the beads to elute the analyte from the beads... Agent: Honeywell International Inc. Patent Services

20090311806 - Gold-binding protein and use thereof: A protein utilizing an anti-gold antibody and a gold-binding side which is a part of the anti-gold antibody is constructed. This protein is capable of specifically binding to gold. This protein or a complex protein containing such a protein can be used for the detection of a target substance.... Agent: Fitzpatrick Cella Harper & Scinto

20090305422 - Methods and reagents for preservation of dna in bodily fluids: Methods, systems and reagents are provided for preserving nucleic acids in a bodily fluid, such as urine, blood, blood serum, and amniotic fluid. The preservative includes an amount of at least one chelator enhancing component selected from the group consisting of lithium chloride, guanidine, sodium salicylate, sodium perchlorate, guanidine thiocyanate,... Agent: King & Spalding LLP

20090305423 - Methods for monitoring composition and flavor quality of cheese using a rapid spectroscopic method: Methods for evaluating cheese comprising using a rapid extraction method and an IR spectra analysis of the cheese are disclosed.... Agent: Macmillan Sobanski & Todd, LLC

20090305424 - Microfluidic flow devices for determining parameters of physical and/or chemical transformations: Microfluidic flow devices for determining parameters of a physical and/or chemical transformation include a body (2), at least one flow microchannel (36) for transferring a mixture (G; T′) of at least two components, such microchannel being formed within the body (2), the or each flow microchannel (36) opening out into... Agent: Buchanan, Ingersoll & Rooney PC

20090305425 - In-line localized monitoring of catalyst activity in selective catalytic nox reduction systems: Localized catalyst activity in an SCR unit for controlling emissions from a boiler, power plant, or any facility that generates NOx-containing flue gases is monitored by one or more modules that operate on-line without disrupting the normal operation of the facility. Each module is positioned over a designated lateral area... Agent: Townsend And Townsend And Crew, LLP

20090305426 - Axial illumination for capillary electrophoresis: System and method for fluorescent light excitation and detection from samples to enhance the numerical aperture and/or reduce the cross-talk of the fluorescent light.... Agent: Life Technologies Corporation C/o Intellevate

20090305427 - Apparatus and process for sensing fluoro species in semiconductor processing systems: A gas detector and process for detecting a fluorine-containing species in a gas containing same, e.g., an effluent of a semiconductor processing tool undergoing etch cleaning with HF, NF3, etc. The detector in a preferred structural arrangement employs a microelectromechanical system (MEMS)-based device structure and/or a free-standing metal element that... Agent: Intellectual Property / Technology Law

20090305428 - Apparatus and method for evaluating a hydrocarbon to determine the propensity for coke formation: An apparatus (10) for evaluating a liquid hydrocarbon to determine the propensity for coke formation comprising an injector (12), a supply of air (14) arranged to supply air to the injector (12) and a supply of liquid hydrocarbon (16) arranged to supply liquid hydrocarbon to the injector (12). The injector... Agent: Oliff & Berridge, PLC

20090305429 - Method for detecting alkylating agents: The present invention relates to methods for detecting alkylating agents in a sample using a chemosensor and measuring the change in measurable properties of chemosensor upon binding. Such changes provide indications of the presence and quantity of alkylating agent in the sample.... Agent: Martin D. Moynihan D/b/a Prtsi, Inc.

20090305430 - Device for preparing bone cement: A method of monitoring the extent of cure of a mixed bone cement includes the steps of taking in hand a flexible polymeric film wherein loaded with a thermochromic material configured to change color at a predetermined temperature; wrapping a quantity of the mixed bone cement in the film such... Agent: Philip S. Johnson Johnson & Johnson

20090305431 - Fluid transfer mechanism: A microfluidic device for transferring liquid from a first chamber to a second chamber is provided. The device has a first chamber; a second chamber; and a barrier between the first chamber and the second chamber, the barrier having least one opening fluidly connecting the first chamber to the second... Agent: Venable LLP

20090305435 - Method of calibrating ligand specificity: A method to determine specificity of ligand binding includes comparing a solid phase carrier first extract obtained by pre-treating a sample with a ligand-immobilized solid phase carrier and a solid phase carrier second extract obtained by treating the pretreated sample again with a ligand-immobilized solid phase carrier in terms of... Agent: Barnes & Thornburg LLP

20090305434 - Method of diagnosing neurophsychiatric diseases, eating disorders or metabolic diseases: The application relates to a method of diagnosing neuropsychiatric diseases, eating disorders and/or metabolic diseases, which comprises: (i) measuring the affinity and/or the avidity of antibodies, derived from a biological sample, directed against a biological molecule involved in homeostatic regulation and/or in motivational behavior and/or in emotion; (ii) comparing the... Agent: Harness, Dickey & Pierce, P.L.C

20090305432 - Polypeptide molecular switch: A polypeptide can conduct electricity in a closed circuit. Conformational changes in the polypeptide due to posttranslational modifications or ligand binding can effect the conductive properties of the polypeptide which can be measured. In such a closed circuit, a polypeptide having at least one residue capable of reversible modification can... Agent: Foley And Lardner LLP Suite 500

20090305433 - Water-soluble rhodamine dye conjugates: The present invention provides novel, water-soluble, red-emitting fluorescent rhodamine dyes and red-emitting fluorescent energy-transfer dye pairs, as well as labeled conjugates comprising the same and methods for their use. The dyes, energy-transfer dye pairs and labeled conjugates are useful in a variety of aqueous-based applications, particularly in assays involving staining... Agent: Kalow & Springut LLP

20090305436 - Device and method for detection of a pregnancy associated hormone: The invention provides a device (10) for detection and providing an indication of the concentration of a single pregnancy associated hormone (especially hCG), comprising a matrix (16) defining an axial flow path, the matrix comprising: (i) a sample receiving zone (18) at the upstream end of the flow path, for... Agent: Birch Stewart Kolasch & Birch