Chemistry: analytical and immunological testing inventions 09/09

20090239306 - Reference material for assaying d-dimer: The present invention relates to a reference material for assaying D-dimer, comprising a fibrin degradation product, wherein no less than 70% of a total peak area has the molecular weight of no less than 500,000 in a molecular weight distribution of the fibrin degradation product, measured by gel filtration chromatography.... Agent: Sughrue Mion, PLLC

20090239307 - Filter with memory, communication and concentration sensor: The present invention describes a system and method for accurately measuring the concentration of a substance within a filter housing. A concentration sensor and a communications device are coupled so as to be able to measure and transmit the concentration of a particular substance within the filter housing while in... Agent: Nields, Lemack & Frame, LLC

20090239308 - Method and apparatus for determining copy number variation using digital pcr: A method of estimating a concentration of DNA molecules in a biological sample includes storing a number of a plurality of reaction sites in a memory and distributing the biological sample among the plurality of reaction sites. The method also includes determining a number of the plurality of reaction sites... Agent: Townsend And Townsend And Crew, LLP

20090239312 - Chromosome 6 and 9 genes involved in premature canities: The invention provides a cosmetic or therapeutic method for combating canities and/or stimulating natural pigmentation and/or treating a pigmentation disorder comprising administering at least one polynucleotide fragment comprising 18 consecutive nucleotides, the sequence of which corresponds to all or part of a gene on human chromosome 9 selected from the... Agent: Buchanan, Ingersoll & Rooney PC

20090239310 - Kokumi-imparting agent: The present invention encompasses a method for screening for a kokumi-imparting substance by using the calcium receptor activity as an index, a composition containing a kokumi-imparting substance obtained by the screening method, a method for producing food or drink imparted with kokumi, and food or drink imparted with kokumi.... Agent: Cermak & Kenealy LLP Acs LLC

20090239311 - Method of differentially diagnosing dementias: In an ex vivo method of differentially diagnosing dementias selected from a group of demetias, which includes vascular dementias and frontotemporal lobe degenerations, a concentration of at least one carboxy-terminally truncated amyloid β peptide species as a biomarker is determined in a body fluid obtained from a patient, the at... Agent: Thomas, Kayden, Horstemeyer & Risley, LLP

20090239309 - Method of stabilizing pulmonary surfactant protein: The invention also provides a kit for assaying a pulmonary surfactant protein present in a sample through an immunological technique employing antigen-antibody reaction, the kit containing, as a standard solution of pulmonary surfactant protein, an aqueous solution containing a pulmonary surfactant protein which has been stabilized by use of a... Agent: Oblon, Spivak, Mcclelland Maier & Neustadt, P.C.

20090233369 - Method for improving chemiluminescent signal: The present invention is directed to compositions and methods for improving a chemiluminescent signal. In particular, a reaction buffer with an alkaline pH range of about 9 to 10 provides a maximal chemiluminescent intensity and longevity of luminol that is catalyzed by superoxide anions. The addition of carbonate to the... Agent: Husch Blackwell Sanders LLP

20090233370 - Method for automatic assay of anionic detergents in seawater: A method for assaying anionic detergents in seawater comprises: (1) flow a sample through a sample system and an analysis-detection system; flow a reference solution through a reference system, a valve, and the analysis-detection system; where the sample and reference are mixed; and flow the mixture into an optical cell... Agent: Connolly Bove Lodge & Hutz, LLP

20090233371 - Method of determining cyclic carbon content in sample and method of determining content of cyclic carbon material in sample: A method for determining a cyclic carbon content in a sample including burning a sample to generate carbon dioxide gas and measuring a total 14C amount in the sample from the carbon dioxide gas; burning the sample to confirm presence or absence of ash; when ash is present, treating the... Agent: Oblon, Spivak, Mcclelland Maier & Neustadt, P.C.

20090233372 - Compositions, kits and methods for determining etiology of trali and detecting patients at risk for this transfusion reaction: The instant application is to compositions, kits and methods to determine if a person in need of a blood transfusion is at-risk for TRALI. The invention includes embodiments of methods for testing the priming activity of a blood component or serum or plasma from a patient sustaining TRALI or the... Agent: Patton Boggs LLP

20090233373 - Multisite phosphorylated peptide (protein) recognizing compound and detection method, imaging method, alzheimer's disease diagnosing method and reagent kit using the same: There are provided a novel compound which captures a multisite phosphorylated peptide or protein specifically to a phosphorylation site and a method for detecting a multisite phosphorylated peptide or protein using the same. In particular, there are provided a compound which specifically detects an excessively phosphorylated tau protein observed in... Agent: Fitzpatrick Cella Harper & Scinto

20090233374 - Flourescent organic nanofibrils as sensory materials for explosives detection: The present invention relates to a class of fluorescent, organic nanofibrils, and particularly the films comprising entangled piling of these nanofibrils exhibiting effective quenching of their fluorescence upon exposure the vapor of explosives. The invention also relates to a sensor and a method for sensing the explosives vapor and other... Agent: Polsinelli Shughart PC

20090233375 - Thermal bath systems and thermally-conductive particulate thermal bath media and methods: Thermally-conductive laboratory bath media can be used to replace conventional wet media or dry solid blocks in existing thermal baths for heating or cooling samples with advantageous maintenance and microbial control benefits. The media is typically in the form of metallic or metallic-coated pellets that have rounded edges, hardened surface,... Agent: William H. Quirk Tuggey Rosenthal Pauerstein

20090233376 - urine gender test kit: A kit for determining the gender of an unborn fetus. The kit comprises a container holding a solid composition therein, the solid composition including a basic salt and a transition metal. An atmosphere in the container is substantially free of water.... Agent: Hitt Gaines P.C.

20090233377 - Microparticle-protein complex, method for production of the complex, semiconductor device, and fluorescent labeling method: First, an ammonium acetate solution and an acetate solution of a metal such as Cd or Zn are mixed, so as to form an ammonium complex of the metal. Next, an apoferritin solution and thioacetic acid are added to the thus obtained reaction solution. By allowing the reaction solution to... Agent: Roberts Mlotkowski Safran & Cole, P.C. Intellectual Property Department

20090233378 - Method of reaction in flow channel of microchip and analysis device: In case of performing a reaction between reacting material and reagent by bringing the reagent in contact with the reacting material through flowing the reagent into a reaction flow channel in which the reaction material which reacts with the reagent is carried on a wall surface of the reaction flow... Agent: Frishauf, Holtz, Goodman & Chick, PC

20090233379 - Taste receptors of the t1r family from domestic dog: The present invention relates to the discovery of several genes of the domestic dog (Canine familiaris) associated with taste perception. The invention provides, inter alia, the nucleotide sequence of the canine Tas1r1, Tas1r2, and Tas1r3 receptor genes, the amino acid sequences of the polypeptides encoded thereby, and antibodies to the... Agent: Woodcock Washburn LLP

20090233380 - Methods and compositions of conjugating gold to biological molecules: The present application describes methods for conjugating gold to biological molecules and conjugates resulting from the same. The method provides superior gold conjugated biomolecules with higher sensitivity than those made from conventional gold conjugation methods.... Agent: Townsend And Townsend And Crew, LLP

20090227033 - Analyzer, sample transportation method, and computer program product: An analyzer comprising: a first measurement unit for measuring samples; a second measurement unit for measuring samples; a transportation device for transporting samples to the first measurement unit and the second measurement unit; prior sample measurement instructor for instructing to measure a predetermined sample prior to the other samples; and... Agent: Brinks Hofer Gilson & Lione

20090227034 - Reactive component reduction system and methods for the use thereof: In accordance with the present invention, there are provided simplified systems and methods for catalytically deactivating, removing, or reducing the levels of reactive component(s) from the vapor phase of fuel storage tanks. The simple apparatus described herein can be utilized to replace complex systems on the market. Simply stated, in... Agent: Foley & Lardner LLP

20090227035 - Method and test kit for the determination of iron content of in-use lubricants: The present invention relates to a method to determine the iron content of in-use lubricants by means of visible spectroscopy. The invention further relates to a test kit using the method. The test may be conducted on-site. The method of the present invention provides an accurate alternative to the standard... Agent: Chevron Corporation

20090227036 - Method of diagnosis of pregnancy-related complications: A method for diagnosing pregnancy-related complications in a pregnant woman is provided. The method includes (a) providing a membrane phospholipid suspension; (b) exposing a first portion of the suspension to standard PP13; (c) exposing a second portion of the suspension to PP13 obtained from the woman; (d) measuring the production... Agent: The Nath Law Group

20090227037 - Novel screening method: By using a G protein-coupled receptor protein comprising an amino acid sequence, which is the same or substantially the same as the amino acid sequence represented by SEQ ID NO: 1, or a salt thereof, and an ionizable metal element or a salt thereof, an agonist for or an antagonist... Agent: Sughrue Mion, PLLC

20090227038 - Methods of determining skeletal maturity: The present invention provides methods to determine skeletal maturity.... Agent: Mintz, Levin, Cohn, Ferris, Glovsky And Popeo, P.c

20090227039 - Detection and quantitation of cyclodextrins: The invention relates to the detection and quantitation of cyclodextrins and cyclodextrin derivatives in solutions comprising a protein. The invention further relates to methods of evaluating pharmaceutical preparations for the presence of residual cyclodextrins.... Agent: Sterne, Kessler, Goldstein & Fox P.l.l.c.

20090227040 - Detection of macromolecular complexes on ultraflat surfaces with harmonic cantilevers: Method and apparatus which uses harmonic cantilevers, such as used in atomic force microscopy, to detect variations in the attractive and repulsive forces on a solid surface as a result of macromolecular binding, for example, hybridization of a single stranded DNA molecule attached to the surface with another DNA molecule.... Agent: Peters Verny , L.L.P.

20090227041 - Centrifugal fluid analyzer rotor: This invention provides rotors and methods of precisely metering a sample fluid and mixing the sample with a reagent. The rotors have a metering tube of defined volume that fills until sample flow is stopped by surface tension of a meniscus at a capillarity port, while excess sample is stripped... Agent: Quine Intellectual Property Law Group, P.C.

20090227042 - Coustic concentration method and device and a reaction method: A method for concentrating materials in a liquid involves pouring the liquid into a material-containing receptacle and irradiating the liquid by acoustic waves so that a stationary flow pattern with different flow rate areas is formed in the receptacle. A concentration device and reaction method using such concentration are also... Agent: Dilworth & Barrese, LLP

20090227043 - Fluorescence resonance energy transfer assay based on modified solid surface: System, including methods, apparatus, and kits, for fluorescence resonance transfer (FRET) binding assays that are surface-based.... Agent: Kolisch Hartwell, P.C.

20090227044 - Microchannel magneto-immunoassay: A single microchannel is combined with external electromagnets for performing a fast immunoassay within a very small volume. Magnetic/luminescent nanoparticles serve as carriers for the antibodies and as internal luminescent standard. The immunoreaction is accelerated by applying alternating magnetic field by means of the external electromagnets, thus inducing oscillation of... Agent: Fenwick & West LLP

20090221079 - Sample pretreatment and extraction: A method for pretreating and extracting a liquid sample by sorbing an aqueous liquid sample, including an organic analyte and an acid or a base, in a solid sorbent material, and at least partially neutralizing the acid or base by reaction with neutralizing ions retained on a support surface, and... Agent: Morgan, Lewis & Bockius, LLP

20090221080 - Various-substance holder, various-substance holder treating apparatus, and various-substance holder treating method: An object of the present invention is to provide a various-substance holder, a various-substance holder treating apparatus, and a various-substance holder treating method which enable the mutual identification of a plurality of particulate carriers to which various substances are or can be immobilized without the need to arrange the particulate... Agent: Haynes And Boone, LLPIPSection

20090221081 - Metabolite markers for weight management: The present invention provides methods of using certain metabolite markers for predicting weight development or its related conditions of a subject. The present invention also provides compositions and kits useful for detecting metabolite markers of the present invention.... Agent: Marshall, Gerstein & Borun LLP (tethys) 233 S. Wacker Drive

20090221082 - Microfluidic evaporators and determining physical and/or chemical properties of chemical compounds therewith: Microfluidic devices having a membrane allowing evaporation are useful for conducting a measurement or observation of compounds introduced therein.... Agent: Buchanan, Ingersoll & Rooney PC

20090221083 - Selective aliphatic c-h oxidation: A composition including a complex of a metal, a tetradentate ligand, at least one ancillary ligand, and a counterion may be used for selective sp3 C—H bond oxidation. The tetradentate ligand may include a N-heterocyclic-N,N′-bis(pyridyl)-ethane-1,2-diamine group or a N,N′-bis(heterocyclic)-N,N′-bis(pyridyl)-ethane-1,2-diamine group. The composition can be used in combination with H2O2 to... Agent: Blanchard & Associates

20090221084 - Method and apparatus for detecting stimulants in a liquid medium: A sensor and testing methodology for detecting and measuring the level of stimulants in a liquid is disclosed. The sensor is compact in form, approximately the size and shape of a fountain pen, and may be conveniently transported in a user's pocket or purse. The device includes a battery, a... Agent: Polsinelli Shughart PC

20090221085 - Thin-layer chromatography and colorimetric analysis of multi-component explosive mixtures: A thin-layer chromatography method for detection and identification of common military and peroxide explosives in samples includes the steps of provide a reverse-phase thin-layer chromatography plate; prepare the plate by marking spots on which to deposit the samples by touching the plate with a marker; spot one micro liter of... Agent: Lawrence Livermore National Security, LLC

20090221086 - Detection method using metallic nano pattern and the apparatus thereof: The present invention relates to an apparatus and a method for detecting the presence of a particular organic, inorganic, metallic, natural or synthetic biomaterial and the concentration thereof. More particularly, the present invention relates to an apparatus and a method for detecting the identity, presence or absence, and concentration of... Agent: Clark & Brody

20090221088 - Fluorescent sensor and methods: Binding an analyte can cause a change in fluorescence emission of a sensor. The change in fluorescence can be related to the amount of analyte present. The sensor can include a semiconductor nanocrystal linked to a fluorescent moiety. Upon excitation, the fluorescent moiety can transfer energy to the semiconductor nanocrystal,... Agent: Steptoe & Johnson LLP

20090221089 - Probe chip, sensing apparatus using the same and method of detecting substances using the same: A probe chip comprises: a prism; a metal film provided on a surface of the prism and which has provided on its surface a first binding material that binds to the analyte; and a channel substrate that is provided on a side of the prism and which has formed therein... Agent: Sughrue Mion, PLLC

20090221087 - Safe biodegradable fluorescent particles: A human-safe fluorescence particle that can be used for fluorescence detection instruments or act as a safe simulant for mimicking the fluorescence properties of microorganisms. The particle comprises a non-biological carrier and natural fluorophores encapsulated in the non-biological carrier. By doping biodegradable-polymer drug delivery microspheres with natural or synthetic fluorophores,... Agent: Lawrence Livermore National Security, LLC

20090221091 - Chemical reaction cartridge, mixture generating method and control device of chemical reaction cartridge: Disclosed is a chemical reaction cartridge including an elastic body as a construction material and a flow path and two or more chambers connected by the flow path formed inside the cartridge, and the cartridge is structured so as to move or block a fluid substance in the flow path... Agent: Sughrue Mion, PLLC

20090221090 - Sample analysis apparatus, sample analysis method, and computer program product: A sample analysis apparatus for analyzing a measurement sample prepared by mixing a sample and a reagent includes a condition memory for storing information regarding a plurality of read conditions; an ID acquirer for reading out identification information at a predetermined position in accordance with a predetermined read condition, the... Agent: Sughrue Mion, PLLC

20090221092 - Lidded microchip for analysis, sample processing method for the lidded microchip, automatic sample processing method for the lidded microchip, automatic sample processing apparatus based on the processing method, and substance analyzing apparatus to which: The present invention provides a method of automating the operation to peel and remove a lid part adhered and fixed to the top surface of a substrate part, which composes a lidded “microchip”, after subjecting a sample liquid to be analyzed to an operation for electrophoretic separation. After subjecting the... Agent: Sughrue Mion, PLLC

20090221093 - Bio-sample carrier for mass spectrometric analyses: A sample carrier has an ultraphobic surface with an affinity zone and a waste zone and/or a zone occupied by a MALDI matrix. Also disclosed is a process for isolating a substance from a mixture of substances, and for its subsequent treatment, as well as a process for purifying a... Agent: Mcdermott Will & Emery LLP

20090221094 - Anthrax polypeptide binding: Methods are disclosed for detecting anthrax protective antigen polypeptides and inhibiting their binding to β2 integrin α. A domain polypeptides, for example β2 integrin receptors. The disclosed methods are useful, for example, in diagnosing the presence of an anthrax toxin in the environment or in a subject and also for... Agent: Fish & Richardson PC

20090221095 - Colorimetric screening of dna binding/intercalating agents with gold nanoparticle probes: Methods are provided to identify and characterize compounds that bind with duplex and triplex polynucleotides.... Agent: Marshall, Gerstein & Borun LLP

20090221097 - Method or agent for inhibiting the function of efflux pump of pseudomonas aeruginosa: The purpose of the present invention is to provide a method and an agent to efficiently inhibit the function of the drug efflux pump of Pseudomonas aeruginosa. The invention provides a method to inhibit the function of the drug efflux pump of Pseudomonas aeruginosa, comprising modifying any amino acid residue... Agent: Bozicevic, Field & Francis LLP

20090221098 - Methods and compositions for obtaining and using biologically active multi-protein complexes: Methods for isolating and using multi-protein complexes that are biologically active are provided. The complexes contain one or more proteins of interest (e.g. a receptor, ion channel, etc.) and associated scaffolding proteins such as phosphatases, kinases and post synaptic density components. Buffers that do not contain denaturing agents and which... Agent: Whitham, Curtis & Christofferson & Cook, P.C.

20090221099 - Methods and compositions for protein detection using fluorescent polymer sensors: Compositions, methods and related apparatus, as can be used for selective protein detection and identification.... Agent: Reinhart Boerner Van Deuren S.c. Attn: Linda Kasulke, Docket Coordinator

20090221100 - Methods for differentiating plasma-derived protein from recombinant protein in a sample: The present invention relates, in general, to methods for detecting and quantitating plasma-derived protein and recombinant protein in a sample based on the difference in protein glycosylation, when the plasma protein and the recombinant protein are essentially the same protein.... Agent: Marshall, Gerstein & Borun (baxter)

20090221096 - Thin film biosensor and method and device for detection of analytes: Thin-film biosensor chips for detecting a target analyte in a biological sample are disclosed. The chips include a solid substrate, an antireflective optical layer, an attachment layer using a non-polymeric silane, and an Fc-specific binding molecule coupled to the non-polymeric silane. Kits containing the chips and methods of using and... Agent: Brinks Hofer Gilson & Lione/utah Utah Office

20090221102 - Method for adding an apparent non-signal line to a lateral flow assay: A test device and method for determining the presence or absence of an analyte in a fluid sample, the test device including a support bearing a mark thereon, and a matrix defining an axial flow path. In operation, an observation area in the test device becomes transparent, thereby allowing the... Agent: King & Spalding LLP

20090221101 - Method for adding an apparent non-signal line to a rapid diagnostic assay: A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or member containing a capture zone. In operation, an observation area in the test device... Agent: King & Spalding LLP