Chemistry: analytical and immunological testing inventions 08/09

20090215180 - Electronic chemical trace detector: A hotplate chemical trace detector comprising a heatable conducting plate with a heater element having a predetermined temperature-power characteristic. A balancing circuit comprises an adjustable resistor for tuning the heater element to a predefined resistor value. A processor is provided for adjusting the adjustable resistor so as to provide a... Agent: Leydig Voit & Mayer, Ltd

20090215181 - Multi-analyte reference solutions: The present invention provides a reference solution for use in instruments that determine hematocrit levels in biological samples by measuring the resistance and/or conductivity of the biological samples. A reference solution according to the invention achieves conductivities representative of known hematocrit levels in blood, while maintaining tolerable levels of interference... Agent: K&l Gates LLP

20090215182 - Method, composition and device for sampling natriuretic peptides in a biological fluid: Disclosed is a composition that synergistically prevents proteolysis or modification of peptides in sampled biological fluids using sulfonyl fluoride family protease inhibitors at high concentrations combined with at least one additional protease inhibitor of a different type, preferably a broad spectrum protease inhibitor, and a chelator. A preferred embodiment uses... Agent: Philip S. Johnson Johnson & Johnson

20090215183 - Specimen analyzer, abnormality control method of the same and computer program product: Specimen analyzer includes a first holding section for holding a container; a first mechanism section for executing a first operation for the container on the first holding section; a second holding section for holding the container; a first transfer mechanism section for transferring the container from the first holding section... Agent: Brinks Hofer Gilson & Lione

20090215184 - Sample analyzer and sample analyzing method: A sample analyzer includes an order receiver for receiving an analyzing order of a sample having analyzing item information; an analyzing section for analyzing a sample according to the analyzing order received by the order receiver; a calculator for counting a first number of analyses by the analyzing section in... Agent: Brinks Hofer Gilson & Lione

20090215185 - Non-signal imidazole reagents for mass spectrometry analysis of phosphomonoesters: Analytical chemical reagents termed non-signal imidazoles and a method for their use that provide a host of advantages for analysis of phosphomonoesters are described. The method and compounds of the invention provide a host of advantages for the analysis of phosphomonoester-containing compounds, namely characteristic, multi-analyte detection with high sensitivity and... Agent: Weingarten, Schurgin, Gagnebin & Lebovici LLP

20090215186 - Method for procyanidin analysis: The present invention relates to a novel method for quantifying procyanidin and flavan-3-ols contained in natural products, foods and drinks, pharmaceuticals and/or cosmetics. The present invention provides a method for quantifying procyanidin (a generic name for a mixture of catechin n-mer; n≧1) contained in test samples such as natural products,... Agent: Drinker Biddle & Reath (dc)

20090215188 - Method for labeling or treating a biological sample containing biological molecules of interest, in particular nucleic acids: e

20090215187 - Methods and compositions for the detection and analysis of nucleic acids by signal amplification: The present invention relates to a novel integrated PCR-free signal amplification polynucleotide detection system which combines a specific receptor, an optical transducer, and an amplification mechanism. This novel detection system is based on different electrostatic interactions and confirmations between a cationic polythiophene (i.e., polymer 1) and single-stranded or double-stranded polynucleotides... Agent: Morgan Lewis & Bockius LLP

20090215189 - Sensor of species including toxins and chemical warfare agents: The present invention generally relates to emissive materials, devices, and related methods. In some cases, the present invention provides sensors and methods for the determination of analytes, wherein the analytes may be determined by monitoring, for example, a change in an optical signal of an emissive material upon exposure to... Agent: Wolf Greenfield & Sacks, P.c.

20090215190 - Apparatus and method for exothermic and endothermic reactions: The present invention generally relates to an apparatus and method for running a plurality of essentially simultaneous exothermic reactions, endothermic reactions, or a combination thereof in sealed reactors and obtaining physico-chemical data, preferably temperature data, and, optionally, time data, for the reactions, wherein reaction mixtures in the sealed reactors are... Agent: The Dow Chemical Company

20090215191 - Optical sensor for detecting chemical reaction activity: The invention provides an optical sensor for detecting chemical reaction activity, including, e.g., enzyme activity and catalytic or reactive molecule activity. An optical sensor of the invention includes a porous photonic film that produces a predetermined spectral reflectance response. In preferred embodiments, the film has a chemical coating (such as... Agent: Greer, Burns & Crain

20090215193 - Application of a reagent to a matrix material: A reagent or particles having reagent supported thereon are applied to a matrix material by a contact printing process for example in which the matrix material is brought into contact with a rotating contact roll having the reagent or particles having reagent supported thereon disposed thereon so as to transfer... Agent: Harness, Dickey & Pierce, P.L.C

20090215194 - Assembly of a microfluidic device for analysis of biological material: In a microfluidic assembly, a microfluidic device is provided with a body in which at least a first inlet for loading a fluid for analysis, and a buried area in fluid communication with the first inlet are defined. An analysis chamber is in fluid communication with the buried area and... Agent: Seed Intellectual Property Law Group Pllc

20090215192 - Solid-phase affinity-based method for preparing and manipulating an analyte-containing solution: A method for preparing an analyte-containing solution, which is compatible with surface-tension-directed liquid droplet manipulation and solid-phase affinity-based assays, is disclosed. The method comprises providing an affinity capture surface comprising a substrate surface having a plurality of first and second surface modifiers associated therewith, wherein the first and second surface... Agent: Seed Intellectual Property Law Group Pllc

20090215198 - Immunological latex turbidimetry method and reagent therefor: (2) bringing a mixture obtained in the above step (1) into contact with latex particles carrying an antibody or antigen specifically reacting with the antigen or antibody to be assayed, and analyzing a turbidity caused by a latex agglutination reaction, is disclosed. Further, an immunological latex turbidimetry reagent comprising (1)... Agent: Sughrue Mion, Pllc

20090215196 - Sequential method: A method for determination of an analyte in an original liquid sample by performing an inhibition affinity assay in a microchannel structure of a microfluidic device. The main characteristic feature is the steps of: (i) providing the microfluidic device in a form where the microchannel structure comprises a reaction microcavity... Agent: Fulbright & Jaworski, LLP

20090215195 - Set1 proteins and uses thereof: The invention relates to methods of use of SET1 proteins or functional equivalents thereof. More particularly the invention relates to the use of SET1 proteins or functional equivalents thereof in procedure, for identification and/or isolation of IgA and the scrum complement factor C5.... Agent: Occhiuti Rohlicek & Tsao, LLP

20090215197 - Target substance capturing molecule: A capturing molecule having not less than two domains specifically binding to different sites of a target substance, wherein the not less than two domains comprise (1) a first domain having a hypervariable loop structure at a binding site to the target substance, and (2) a second domain having no... Agent: Fitzpatrick Cella Harper & Scinto

20090215199 - Caffeine detection via internally-referenced two part assay: Methods, compositions, and apparatus for detecting the presence of caffeine in a liquid sample are provided. In certain embodiments, an internally referenced competitive assay allows a very precise determination of a threshold value of caffeine for use in semiquantitative types of ligand-receptor assays. By using a detection means that participates... Agent: Fenwick & West LLP

20090215200 - Measurement of binding rate of a binding substance and an analyte: A method of measuring the rate of binding of a binding substance and an analyte, for example in an assay such as an immunoassay, uses an initial step of performing ultrasonication sufficient to disrupt binding between the binding substance and the analyte. After cessation of the ultrasonication, measurements are taken... Agent: Harness, Dickey & Pierce, P.L.C

20090209040 - Sensor release mechanism for a meter: A sensor-dispensing instrument (10) adapted to handle a sensor pack containing a plurality of sensors and to perform a test using one of the sensors. The sensor-dispensing instrument includes an outer housing (12) and a mechanical mechanism contained therein for rotating the sensor pack and ejecting one of the sensors... Agent: Nixon Peabody LLP

20090209041 - Peptides and methods for inhibiting amyloid formation: A peptide comprising at least 5 amino acid residues and less than 15 amino acid residues, the peptide including an amino acid sequence as set forth in SEQ ID NO: 7 as well as pharmaceutical compositions, kits and methods for diagnosing and treating amyloid associated diseases.... Agent: Martin D. Moynihan D/b/a Prtsi, Inc.

20090209042 - Controllable magnetic system for biosensors: The invention relates to a magnetic system for biosensors and in particular to a magnetic system which can switch between attraction force and repulsion force near the sensor surface with more easy but also more effective means. This is realised with at least one coil (2) and at least two... Agent: Philips Intellectual Property & Standards

20090209043 - Device and method for holding a cassette for laboratory samples: A device (1) for holding a laboratory sample cassette (2) having a marking surface (3) disposed at an inclined angle to a main body of the cassette (2), has a platen (10) with an aperture through which marking of the marking surface (3) can occur. The device (1) also has... Agent: Fay Sharpe LLP

20090209044 - Fluid sample collection system and method: A fluid sample collection system includes a vial, a plunger and a fluid sample collection device having an absorbent for absorbing and retaining a fluid sample therein. The plunger includes an elongated handle portion and a plunger head portion detachably connected to the handle portion. The plunger also includes a... Agent: Wood, Herron & Evans, LLP

20090209047 - Biomarkers and assays for myocardial infarction: Presented herein are novel blood plasma/serum biomarkers related to cardiovascular disease. These newly identified biomarkers create the basis for multiple (single) assays using traditional bioassay technologies and when used in combination yield exceptional clinical sensitivity and specificity in the determination of myocardial infarction (MI). A multiplexed, mass spectrometric immunoassay (MSIA)... Agent: Snell & Wilmer L.L.P. (main)

20090209048 - Luminescence biotin-transition metal complex conjugate, and method of amplifying signal using the same: Disclosed are a luminescence biotin-transition metal complex conjugate and a method of amplifying signals using the same. More particularly, disclosed herein are a luminescence biotin-transition metal complex conjugate comprising an energy acceptor and biotin, and optionally an energy donor and a method of amplifying signals using the biotin-transition metal complex... Agent: Cantor Colburn, LLP

20090209046 - Neutral pharmaceuticals: The invention comprises neutral multi-functionality assemblies of pharmaceuticals comprising an active medicinal functionality, a transition metal functionality, and an ancillary ligand functionality. An exemplary series of mixed-ligand coordination complexes comprised of copper(II), a drug and an ancillary ligand were made and tested. It is demonstrated that the judicious choice of... Agent: Hamilton, Brook, Smith & Reynolds, P.C.

20090209045 - Screening assay: The present invention relates to agents that modulate the interaction of a dopamine receptor interacting polypeptide (DRIP) as represented by FIGS. 1 to 11 and to screening methods for the identification of such agents.... Agent: Speckman Law Group PLLC

20090209049 - Use of metal complexes: A method of immobilising a target molecule on a substrate, which comprises exposing the target molecule to the substrate in the presence of a metal complex, wherein the target molecule is an unmodified target molecule, and wherein the metal complex is selected to provide a stable binding interaction between the... Agent: Howrey LLP-ca

20090203145 - Methods for analysis of vitamins: The invention relates to methods for determining the level of B vitamins in a test sample. The methods can include the steps of obtaining a water soluble vitamin fraction by extraction in acidic aqueous solution of a test sample, wherein the vitamin fraction comprises one or more B vitamins having... Agent: Mcdermott, Will & Emery

20090203146 - Narrow bore layer open tube capillary column and uses thereof: A polymer-based PLOT column prepared by in situ copolymerization of a functional monomer, which usually contains the retentive chemistries, and a crosslinking monomer, which enhances the strength of the polymer matrix, is disclosed. Styrenic based monomers such as styrene and divinylbenzene or meth/acrylic based monomers such as butyl or stearyl... Agent: Weingarten, Schurgin, Gagnebin & Lebovici LLP

20090203147 - Blotting detection method: It is an object of the present invention to provide a blotting detection method capable of quick detection of a very tiny amount of an analysis target. The present invention provides a blotting detection method which comprises moving an analyte held on a first carrier with a developing solution, and... Agent: Birch Stewart Kolasch & Birch

20090203148 - Methods and devices for detection and identification of encoded beads and biological molecules: The invention relates to methods and devices used in the sequencing, separation, detection, and identification of objects and biological molecules. In preferred embodiments, the invention relates to a DNA sequencing system based on cyclic sequencing by synthesis which is performed on beads in three-dimensional vessels and detected using monolithic multicapillary... Agent: Peter G. Carroll Medlen & Carroll, LLP

20090203149 - Enhanced methods for gas and/or vapor phase analysis of biological assays: Processes for improved efficiencies as it relates to the analysis of small molecules whose concentration in the analysis solution is dependent upon the concentration of a target as determined through a liquid phase biological assays with vapor and/or gas phase analysis are disclosed. The process generally includes the competitive or... Agent: General Electric Company Global Research

20090203150 - Methods and systems for identifying insulin mimetics: Methods are provided for identifying and selecting candidate molecules that activate glucose transport through binding of the insulin receptor at a site other than the insulin binding site. The methods include analyzing the properties of one or more candidate molecules in terms of the ability to bind the insulin receptor... Agent: Calfee Halter & Griswold, LLP

20090203151 - Immunoassay method: It is an object of the present invention to provide an immunoassay method which is capable of simultaneous quantification of a plurality of test substances under a same analysis condition, through adjustment of the measurement sensitivity/range by simply varying the size of particles for use as labels, without changing the... Agent: Birch Stewart Kolasch & Birch

20090203152 - Method for analyzing an analyte qualitatively and quantitatively: A specific binding analysis method capable of controlling the amount of specific binding to freely setting the sensitivity, concentration range and the like in an analysis, and a device used therefore are provided. In order to optimize the amount of specific binding, the specific binding analysis method and the device... Agent: Panitch Schwarze Belisario & Nadel LLP

20090203153 - Metal particle and a testing method using the same: An object of the present invention is to provide a metal particle with which a highly-sensitive testing method can be conducted, and a testing method using such metal particle. The present invention provides a metal particle, which is produced by coating a metal particle labeled with a molecule binding to... Agent: Birch Stewart Kolasch & Birch

20090203154 - Method for sensing a chemical: This invention relates to a method for detecting an analyte in a sample. The method comprises the steps of exposing the sample to a transducer having a pyroelectric or piezoelectric element and electrodes which is capable of transducing a change in energy to an electrical signal, the transducer having at... Agent: Rothwell, Figg, Ernst & Manbeck, P.C.

20090203155 - Labeled particle obtained by immobilizing a fragmented antibody to a labeling substance: An object of the present invention is to provide a labeled particle having a high reactivity with an antigen and a suppressed non-specific adsorption, and an immunochromatographic method using the labeled particle. The present invention provides a labeled particle, wherein a fragmented antibody is immobilized to a labeling substance via... Agent: Birch Stewart Kolasch & Birch

20090203145 - Methods for analysis of vitamins: The invention relates to methods for determining the level of B vitamins in a test sample. The methods can include the steps of obtaining a water soluble vitamin fraction by extraction in acidic aqueous solution of a test sample, wherein the vitamin fraction comprises one or more B vitamins having... Agent: Mcdermott, Will & Emery

20090203146 - Narrow bore layer open tube capillary column and uses thereof: A polymer-based PLOT column prepared by in situ copolymerization of a functional monomer, which usually contains the retentive chemistries, and a crosslinking monomer, which enhances the strength of the polymer matrix, is disclosed. Styrenic based monomers such as styrene and divinylbenzene or meth/acrylic based monomers such as butyl or stearyl... Agent: Weingarten, Schurgin, Gagnebin & Lebovici LLP

20090203147 - Blotting detection method: It is an object of the present invention to provide a blotting detection method capable of quick detection of a very tiny amount of an analysis target. The present invention provides a blotting detection method which comprises moving an analyte held on a first carrier with a developing solution, and... Agent: Birch Stewart Kolasch & Birch

20090203148 - Methods and devices for detection and identification of encoded beads and biological molecules: The invention relates to methods and devices used in the sequencing, separation, detection, and identification of objects and biological molecules. In preferred embodiments, the invention relates to a DNA sequencing system based on cyclic sequencing by synthesis which is performed on beads in three-dimensional vessels and detected using monolithic multicapillary... Agent: Peter G. Carroll Medlen & Carroll, LLP

20090203149 - Enhanced methods for gas and/or vapor phase analysis of biological assays: Processes for improved efficiencies as it relates to the analysis of small molecules whose concentration in the analysis solution is dependent upon the concentration of a target as determined through a liquid phase biological assays with vapor and/or gas phase analysis are disclosed. The process generally includes the competitive or... Agent: General Electric Company Global Research

20090203150 - Methods and systems for identifying insulin mimetics: Methods are provided for identifying and selecting candidate molecules that activate glucose transport through binding of the insulin receptor at a site other than the insulin binding site. The methods include analyzing the properties of one or more candidate molecules in terms of the ability to bind the insulin receptor... Agent: Calfee Halter & Griswold, LLP

20090203151 - Immunoassay method: It is an object of the present invention to provide an immunoassay method which is capable of simultaneous quantification of a plurality of test substances under a same analysis condition, through adjustment of the measurement sensitivity/range by simply varying the size of particles for use as labels, without changing the... Agent: Birch Stewart Kolasch & Birch

20090203152 - Method for analyzing an analyte qualitatively and quantitatively: A specific binding analysis method capable of controlling the amount of specific binding to freely setting the sensitivity, concentration range and the like in an analysis, and a device used therefore are provided. In order to optimize the amount of specific binding, the specific binding analysis method and the device... Agent: Panitch Schwarze Belisario & Nadel LLP

20090203153 - Metal particle and a testing method using the same: An object of the present invention is to provide a metal particle with which a highly-sensitive testing method can be conducted, and a testing method using such metal particle. The present invention provides a metal particle, which is produced by coating a metal particle labeled with a molecule binding to... Agent: Birch Stewart Kolasch & Birch

20090203154 - Method for sensing a chemical: This invention relates to a method for detecting an analyte in a sample. The method comprises the steps of exposing the sample to a transducer having a pyroelectric or piezoelectric element and electrodes which is capable of transducing a change in energy to an electrical signal, the transducer having at... Agent: Rothwell, Figg, Ernst & Manbeck, P.C.

20090203155 - Labeled particle obtained by immobilizing a fragmented antibody to a labeling substance: An object of the present invention is to provide a labeled particle having a high reactivity with an antigen and a suppressed non-specific adsorption, and an immunochromatographic method using the labeled particle. The present invention provides a labeled particle, wherein a fragmented antibody is immobilized to a labeling substance via... Agent: Birch Stewart Kolasch & Birch

20090197340 - Method for determining the nutritional quality of milk lipids: A method for determining the nutritional quality of milk lipids, involving the steps consisting in considering a defined number of reference milk samples; determining, for each of said reference samples, a fatty acid profile and an infrared spectrum obtained through reflection on the reference sample of a radiation in the... Agent: Akerman Senterfitt

20090197342 - Marker for inflammatory conditions: Use of pregnancy-associated plasma protein-A as a marker for inflammatory conditions, and in particular, for acute coronary syndromes is described.... Agent: Fish & Richardson P.C.

20090197341 - Water soluble film based matrix to collect samples extracted from living species: The invention relates to a water soluble film based matrix for collecting blood samples, urine samples, serum samples or any other type of samples extracted from living species; so as to avoid cross infection or spillage of samples during transportation of said samples. These samples can then used for further... Agent: Amin Talati, LLC

20090197344 - Method for the prediction of vascular events and the diagnosis of acute coronary syndrome: wherein the presence and/or levels of at least two different biochemical markers are measured in a biological sample of said patient, whereby the probability that the patient will experience a vascular event or the vascular-related condition is deduced from the measured presence and/or levels of the biochemical markers.... Agent: Jacobson Holman PLLC

20090197343 - Methods for detection of pathogenic prion proteins associated with prion diseases, using conjugated polyelectrolytes: The present invention relates to a method for detecting the presence of a pathogenic prion species in a sample comprising the steps—bringing the sample in contact with at least one conjugated polyelectrolyte (CPE)—irradiating the CPE with electromagnetic radiation—measuring the radiation emitted or absorbed by the CPE at at least one... Agent: Young & Thompson

20090197345 - Method for quantification of allergens: The invention relates to method for quantification of the absolute amount of allergen in an allergen sample comprising: a) providing a known amount of one or more allergen calibration standard peptide(s) having a sequence of amino acids which is identical with, and optionally unique for, a sequence to be found... Agent: Darby & Darby P.C.

20090197346 - Compositions and methods for preserving rna in biological samples: The present invention concerns methods and compositions to prepare biological samples to preserve the macromolecules in the samples. Embodiments of the invention concern the use of a soak solution that contains one or more water-miscible solvents. A sample is incubated with the soak solution to the point of saturation at... Agent: Invitrogen Corporation C/o Intellevate

20090197349 - Electrochemiluminescence of rare earth metal chelates: Luminescent chemical reagents that include complexes of rare earth metals with ligands such as aromatic heterocyclic nitrogen-containing compounds and semi-aromatic oxygen-containing compounds are used to detect small quantities of complex substances such as pharmaceuticals, metabolites, and microorganisms in complex sample mixtures.... Agent: Foley & Lardner LLP

20090197347 - Immunoassay for plasmodium falciparum and assay device used therefor: The present invention can effect specific detection of antigens and/or antibodies in patients with manifested malaria-symptoms as well as malaria carriers and can also be efficiently employed in samples at the early stage of malaria infection that is difficult to detect via conventional arts. Further, due to the capacity to... Agent: Cantor Colburn, LLP

20090197348 - Pyrocatechol violet-metal protein assay: A method for protein determination utilizing a pyrocatechol violet-metal complex, a composition used in the protein determination assay, and a kit.... Agent: Thompson Hine L.L.P. Intellectual Property Group