Chemistry: analytical and immunological testing inventions 03/09

20090081794 - Sample analyzer and method for analyzing samples: An sample analyzer, which enables to confirm an analysis remaining time for each sample and a total analysis remaining time for all samples set in the analyzer, so that time management for both each sample and all samples can be easily performed, is disclosed. Specifically, an analyzing unit analyzes a... Agent: Brinks Hofer Gilson & Lione

20090081795 - Identification of humans through characteristic compounds detected in human scent: The present invention is directed to methods of identifying and/or comparing humans. More particularly, the present invention is directed to methods of collecting human scent compounds from a subject, extracting the compounds, analyzing the compounds, and correlating the compounds to a unique compound profile for the subject. These unique compound... Agent: Marshall, Gerstein & Borun LLP

20090081796 - Method for the determination of phospholipids in amniotic fluid samples: The present invention refers to a fast method for the determination of phospholipids in amniotic fluid samples by HPTLC (high performance thin layer chromatography). This innovative method presents high sensitivity, reproducibility and resolution. It has also the advantage of being of easy laboratorial interpretation, allowing the elimination of false results... Agent: Sughrue Mion, PLLC

20090081799 - Analyte evaluation device and analyte evaluation method: An analyte evaluation device includes: a light irradiator for inducing fluorescence emission from an analyte; a carrier for positioning the analyte; and a fluorescence detector for receiving the fluorescence, wherein the light irradiator and the fluorescence detector are situated on mutually opposing sides of the carrier, light irradiated from the... Agent: Westerman, Hattori, Daniels & Adrian, LLP

20090081798 - Protein s functional assay: The invention relates generally to a new functional protein S assay and kit that is based on the ability of endogenous protein S to prolong clotting time. In the assay procedure, a test plasma sample is diluted with protein S deficient plasma, followed by the addition of purified or recombinant... Agent: K&l Gates LLP

20090081797 - Reactive surface on a polymeric substrate: Plasma treated cyclic polyolefin copolymer surfaces having enhanced binding density for binding biologically active agents and cells are provided. These plasma treated cyclic polyolefin copolymer surfaces may be further enhanced for binding biologically active agents or cells by the application of conjugates. Methods of making and characterizing treated polymer surfaces... Agent: Corning Incorporated

20090081800 - Selective resonance of chemical structures: Chemical compositions may be selectively or preferentially excited by the application of scores comprising a series of energy inputs.... Agent: Searete LLC Clarence T. Tegreene

20090081801 - Process for synthesis of pyrrole derivative, an intermediate for atorvastatin: The present invention also provides an improved process for preparing (4R,cis)-6-[2-[3-phenyl-4-(phenyl-carbamoyl)-2-(4-fluorophenyl)-5-(1-methyl-ethyl)-pyrrole-1-yl]-2,2-dimethyl-[1,3]dioxane-4-yl-acetic acid-tertiary butyl ester, the compound of formula I, said process comprising the step of condensing 4-fluoro-α-[2-methyl-1-oxopropyl]-γ-oxo-N,β-diphenylbenzene butanamide, the compound of formula III, with (4R,Cis)-1,1-dimethylethyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate, the compound of formula II, in the presence of a catalytic amount of an acid... Agent: Kenyon & Kenyon LLP

20090081802 - Method for enriching short-chain nucleic acids: e

20090081803 - Polyviologen boronic acid quenchers for use in analyte sensors: The invention relates to a class of glucose-responsive, polyviologen boronic acid quenchers that may be used in combination with fluophores to achieve real-time measurement of glucose levels in vivo.... Agent: Knobbe Martens Olson & Bear LLP

20090081804 - Monitor and methods for characterizing airborne particulates: A dust monitor is disclosed that is suitably deployed in dusty environments and capable of providing near real-time indications of exposure to airborne particulates. The monitor includes a filter and filter assembly made of materials that do not interfere with subsequent instrumental (such as spectrometric) analysis for detecting and/or quantitating... Agent: Klarquist Sparkman, LLP

20090081805 - Method for finding active ingredients from chemical and biological systems: The present invention relates to a method for finding active ingredients/groups of constitutes from a multi-component system that are active as indicated by specific or a group of activity test. The method involves the use of a hyphenated instrument for determining the active ingredients.... Agent: The Hong Kong Polytechnic University Suite 600, Mailbox #119

20090081806 - Methods and compositions for ph control: The present invention comprises methods and compositions for controlling the pH of a confined body of water, such as a swimming pool, spas, and hot tubs, using an organic acid specifically citric acid alone or in combination with other organic acids, borates or boric acid or other chelants or clarifiers.... Agent: Troutman Sanders LLP Ryan A. Schneider, Esquire

20090081807 - Method for rapid and quantitative assay using primary color principle: A method for rapid and quantitative assay of fluid specimen is disclosed. This method utilizes the principle of primary colors: any color can be discomposed into three primary colors or multiple primary colors (for example, red, green and blue). The molecules of the chemical being measured are bound to three... Agent: April Cui

20090081808 - Device and method for identifying mycotoxins: The invention relates to an apparatus and a process for detection of mycotoxins and to kits suitable for carrying out said process.... Agent: Norris, Mclaughlin & Marcus, Pa

20090081809 - Monoclonal antibody specific to dentin-derived heparan sulfate: The present invention provides a monoclonal antibody displaying excellent specificity against heparan sulfate saccharide chains for the analysis of heparan sulfate saccharide chains specific to dentin. The invention also provides a method of evaluating reproductive dentin using the monoclonal antibody. The anti-heparan sulfate monoclonal antibody reacts against dentin-derived heparan sulfate... Agent: Antonelli, Terry, Stout & Kraus, LLP

20090075385 - Reaction vessel support having pivoting plates, an analyzing device comprising a support of this type, and corresponding analysis method: P

20090075386 - Clog detection in a clinical sampling pipette: Analyzing the pressure profile generated during a predetermined period of time prior to the end of an aspiration or dispensing process and comparing a pressure reading to predetermined values to determine if the aspiration or dispensing pipette was free of clogs.... Agent: Dade Behring Inc. Legal Department

20090075387 - Methods and compositions for biomarkers associated with change in physical performance: The present invention provides methods and compositions for detecting an improvement in the performance of a physical or athletic activity and/or in a cognitive activity in a subject upon administration to the subject of a performance enhancing material and/or upon contact of the subject with a performance enhancing material and/or... Agent: Myers Bigel Sibley & Sajovec

20090075388 - Stable isotope-labeled aliphatic amino acids, method for incorporating the same in target protein and method for nmr-structural analysis of proteins: e

20090075389 - Method for determining an analyte in a fluid: A reagent strip for measuring the concentration of glucose in whole blood has a polymer on at least one side thereof to increase the opacity thereof, thereby reducing the effect of hematocrit on the glucose determination.... Agent: Nixon Peabody LLP

20090075390 - Liquid containment for integrated assays: Microfluidic systems including liquid containment regions and methods associated therewith for performing chemical, biological, or biochemical analyses are provided. Liquid containment regions of a microfluidic device may include regions that capture one or more liquids flowing in the device, while allowing gases or other fluids in the device to pass... Agent: Wolf Greenfield & Sacks, P.C.

20090075391 - Spectroscopic diagnostic method and system based on scattering of polarized light: The present invention provides systems and methods for the determination of the physical characteristics of a structured superficial layer of material using light scattering spectroscopy. The light scattering spectroscopy system comprises optical probes that can be used with existing endoscopes without modification to the endoscope itself. The system uses a... Agent: Weingarten, Schurgin, Gagnebin & Lebovici LLP

20090075392 - Agents for and method of quanitifying multiple related components in a biological system: The present invention relates to agents comprising non-natural protein sequences with at least two protein or polypeptide epitopes that are relationally linked by a common or shared functional relationship such as being components in a series of components of the same metabolic or signal transduction pathway or a pathway associated... Agent: Myers Bigel Sibley & Sajovec

20090075393 - Integrated affinity microcolumns and affinity capillary electrophoresis: Device and method for detecting the presence of known or unknown toxic agents in a fluid sample. Targets in the sample are bound to releasable receptors immobilized in a reaction region of a micro- or nano-fluidic device. The receptors are selected based on their affinity for classes of known toxic... Agent: Gonzales Patent Services

20090075394 - Voltage sensor domains of voltage-dependent ion channel proteins and uses thereof: A composition of matter suitable for use in identifying chemical compounds that bind to voltage-dependent ion channel proteins, the composition comprising a screening protein that comprises an ion channel voltage sensor domain of the ion channel protein immobilized on a solid support.... Agent: Hoffmann & Baron, LLP

20090075395 - Multiplexed biomarkers for monitoring the alzheimer's disease state of a subject: The present invention relates to a method for diagnosing a subject's Alzheimer's disease state. The method involves providing a database containing information relating to protein expression levels associated and not associated with Alzheimer's disease. The database includes information relating to at least a majority of the following proteins: albumin, alpha-1-antitrypsin,... Agent: Nixon Peabody LLP - Patent Group

20090075396 - Biosensors: Methods for detecting a biological interaction comprising administering a substrate comprising a ligand attached to the substrate wherein the ligand binds to a receptor and wherein a signal is produced. Also disclosed is a biosensor comprising a substrate and a ligand wherein the ligand is attached to the surface of... Agent: Venable LLP

20090075397 - Method for characterizing sugar-binding interactions of biomolecules: This invention provides a donor bead for use in an assay, wherein the bead (a) is coated with a layer of hydrogel having directly or indirectly bound thereto a polyacrylamide-supported sugar or a polyacrylamide-supported glycan, and (b) comprises a photosensitizer which, upon excitation by laser light of a suitable wavelength,... Agent: Cohen, Pontani, Lieberman & Pavane LLP

20090075398 - Method for obtaining antibodies: A method of obtaining at least one recombinant antibody with improved affinity for a selected antigen from a family of antibodies which bind the selected antigen comprising: a) obtaining a family of two or more antibodies which bind the same antigen in which the VH CDR3 amino acid sequence of... Agent: Mcdonnell Boehnen Hulbert & Berghoff LLP

20090068746 - Method for measuring interaction between physiologically active substance and test substance: It is an object of the present invention to provide a method for measuring the interaction between a physiologically active substance immobilized on the surface of a substrate and a test substance, wherein the influence of negative signals intermittently generated due to desorption of the physiologically active substance as a... Agent: Sughrue Mion, PLLC

20090068747 - Apparatus for emitting and detecting light in a nucleic acid amplification reaction: Subject of the present invention is to provide an apparatus, an instrument, and a method particularly useful in multiplex PCR applications permitting short sample measuring times of many samples combined with high sensitivity.... Agent: Roche Molecular Systems, Inc. Patent Law Department

20090068748 - Automatic analyzer and operating method for same: An automatic analyzer is free from limitations on layout of various mechanisms, and thus causing no bottlenecks, for example, in a space-saving design of the automatic analyzer. This invention includes a coaxial planar duplex arrangement of two dilution disks each with annularly disposed dilution cells, and the dilution disks A... Agent: Mattingly, Stanger, Malur & Brundidge, P.C.

20090068749 - Module for automated matrix removal in acidic plating solutions: In accordance with the present invention, an organic additive is characterized in the presence of an acidic metal plating matrix in a metal plating solution by: providing a sample from the metal plating solution; activating a metal-complexing resin with a weak acid to provide an activated metal-complexing resin; eluting the... Agent: Macpherson Kwok Chen & Heid LLP

20090068750 - Method of determining iron concentration: By performing the method of measuring iron concentration of the present invention, the conventional problem that the measured value is lower as compared with that obtained by the International Standard Method is solved; a complicated procedures such as protein removal treatment or the like are not required; the measurement of... Agent: Hamre, Schumann, Mueller & Larson, P.C.

20090068752 - Method for preparing analysis sample, analysis sample and sugar chain capture agent: A method for preparing an analysis sample which involves the sugar chain capture step comprising a reaction of capturing a sugar chain and/or a sugar derivative from a biological sample by using a sugar chain capture agent and the excision step comprising excising a compound containing a moiety capturing the... Agent: Smith Gambrell & Russell

20090068751 - Methods of labelling polynucleotides with dibenzorhodamine dyes: including nitrogen- and aryl-substituted forms thereof, wherein substituents at positions C-14 to C18 taken separately are selected from the group consisting of hydrogen, chlorine, fluorine, lower alkyl, carboxylic acid, sulfonic acid, —CH2OH, alkoxy, phenoxy, linking group, and substituted forms thereof. The invention further includes energy transfer dyes comprising the dibenzorhodamine... Agent: Dechert LLP

20090068753 - Detection of bromamines and chloramines: A method for the detection of chloramines and bromamines which are indicative markers particularly of lung diseases using flow tube, drift tube or atmospheric chemical ionisation technologies. The method can also be utilised to detect oxidative stress related diseases, test the prophylactic effect of drugs given to a patient, and... Agent: D. Peter Hochberg D. Peter Hochberg Co.

20090068754 - Transient decay amperometry: A biosensor system determines an analyte concentration of a biological sample using an electrochemical process without Cottrell decay. The biosensor system generates an output signal having a transient decay, where the output signal is not inversely proportional to the square root of the time. The transient decay is greater or... Agent: Blanchard & Associates

20090068757 - Apparatus, process and kit for detecting analytes in a sample: The invention relates to an apparatus (100) for detecting analytes (26) in a sample comprising—a base carrier (10); —a multitude of sensor carriers (18) which are arranged on the base carrier (10) and can be assigned to at least two different sensor carrier populations (181, 182, 183); —the sensor carrier... Agent: Nixon Peabody LLP

20090068756 - Methods for determining organic biocide concentration in a composite wood product: A composite wood product and methods for manufacturing the same and determining the concentration and distribution of an organic biocide within a composite wood product are provided. The organic biocide may be added to wood elements (i.e., fibers, flakes, strands, veneers) prior to consolidation and/or heating of the wood particles... Agent: Weyerhaeuser Company Intellectual Property Dept., Ch 1j27

20090068755 - Optical biosensing platform utilizing nanocrystalline zinc oxide: An optical biosensing platform for the real-time detection of the occurrence of a binding event, the optical biosensing platform comprising a nanocrystalline zinc oxide (nano-ZnO) substrate having a surface and being capable of emitting photoluminescence and a surface modifier formed integral with at least a portion of the surface of... Agent: Natick Soldier Rdec

20090068758 - Synthetic receptor: A polymer capable of selectively binding alfentanil is prepared from one or more suitable monomers (e.g. ethylene glycol methacrylate phosphate) and a cross-linker. It may be a molecularly imprinted polymer. An element (7) of the polymer may be used in an alfentanil sensor (1) mounted in a confinement structure (3)... Agent: Stites & Harbison PLLC

20090068760 - Microfluidic assay system with dispersion monitoring: Disclosed is a microfluidic assay system and methods that apply flow injection analysis to permit dispersion monitoring. A solution containing a reagent that binds an analyte and a tracer is delivered via pressure-driven flow into the receiving end of the injection channel of the system of the invention. A sample... Agent: Karen S. Canady Canady & Lortz LLP

20090068759 - Reusable detection surfaces and methods of using same: The technology provided herein generally relates to reusable detection surfaces and methods for reusing a detection surface after using the detection surface in an assay for an analyte.... Agent: Proskauer Rose LLP

20090061522 - Automated protein analyzer: A direct rapid automated protein analyzer is disclosed. The protein analyzer includes means for reducing protein samples to small particles, a reaction vessel in material transfer communication with the homogenizer, a reservoir for binding dye composition in fluid communication with the reaction vessel, a metering pump in fluid communication with... Agent: Summa, Additon & Ashe, P.A.

20090061524 - Enzyme-channeling based electrochemical biosensors: Low-cost, non-toxic and fast immunoassay systems (immunosensors) and uses thereof as analytical and diagnostic tools for detecting an immune response in a subject are disclosed. The systems and methods disclosed are based on recording an electrochemical signal which is generated proportionally to an enzymatic cascade reaction (enzyme-channeling) upon detecting an... Agent: Martin D. Moynihan D/b/a Prtsi, Inc.

20090061523 - Mass defect labeling and methods of use thereof: Briefly described, embodiments of this disclosure include mass defect labeled peptides, methods of identifying peptides, and the like.... Agent: Thomas, Kayden, Horstemeyer & Risley, LLP

20090061525 - On-chip analysis of covalently labelled sample species: A method for analyzing a sample comprising different sample compounds is described. The method comprises staining the sample compounds by adding a dye species to a solution of the sample, the dye species having reactive groups adapted for forming covalent bonds with specific groups of the sample compounds, and providing... Agent: Agilent Technologies Inc.

20090061527 - Methods and devices for detecting nucleic acid hybridization: The present invention provides novel methods and devices for detecting hybridization of nucleic acids using liquid crystals and cationic surfactants.... Agent: Townsend And Townsend And Crew, LLP

20090061526 - Nucleic acid sequencing by selective excitation of microparticles: Nucleic acid microparticles are sequenced by performing a sequencing reaction on the microparticles using one or more reagents, selectively exciting the microparticles in an excitation pattern, optically imaging the microparticles at a resolution insufficient to resolve individual microparticles, and processing the optical images of the microparticles using information on the... Agent: Fenwick & West LLP

20090061528 - Hpts-mono and bis cys-ma polymerizable fluorescent dyes for use in analyte sensors: Novel fluorescent dyes are disclosed for use in analyte detection. In particular, mono- and bis-substituted HPTS dyes and methods of making them are provided.... Agent: Knobbe Martens Olson & Bear LLP

20090061529 - Method for detecting substance in liquid and sensor for detecting substance in liquid: A method for detecting a substance in a liquid with high accuracy and high sensitivity includes recording frequency drifts of output frequencies of oscillator circuit outputs of m sensing oscillator circuits respectively including sensing SAW elements and frequency drifts of output frequencies of oscillator circuit outputs of n reference oscillator... Agent: Murata Manufacturing Company, Ltd. C/o Keating & Bennett, LLP

20090061530 - Method for designating a component having a heat insulation layer and for determining its operating time: A method for designating a component, coated with a heat insulation layer including zirconium dioxide (ZrO2) stabilized with yttrium oxide (Y2O3) [YSZ], and for determining its operating time or operating temperature is provided. The method includes doping the heat insulation layer and marking the doped heat insulation layer, with at... Agent: Volpe And Koenig, P.C. Dept. Alstom

20090061531 - Dna binding protein: Methods of screening for compounds which are, for example, capable of modulating amino acid-DNA interaction, modulating DNA replication, modulating cell proliferation, and for identifying compounds which inhibit cellular proliferation caused by cancer, are provided.... Agent: Dinsmore & Shohl LLP

20090061532 - Fluorescence resonance energy transfer detection with nanoparticles for in vitro and in vivo applications: A combination of nanoparticles is disclosed comprised of amine functionalized polyethylene glycol in which one particle with a fluorescent donor dye having one wavelength excitation maximum and at least one additional particle with a second fluorescent dye having a second, higher wavelength excitation maximum, the particles having the same or... Agent: Patent Legal Staff Carestream Health, Inc.

20090061534 - Assay device with shared zones: Disclosed is an assay device for determining the presence and/or extent of one or more analytes in liquid sample containing a) first and second assays each comprising a flow-path having a detection zone for immobilising a labelled binding reagent, wherein detection of a labelled binding reagent at one or both... Agent: Foley Hoag, LLP Patent Group (w/isa)

20090061535 - Method of adjusting the working range of multi-analyte assay: The invention features a method of adjusting the concentration of at least one but not all of a plurality of analytes in a fluid sample to match a known working range of detection of an analyte assay system, where each of the plurality of analytes may or may not be... Agent: Leslie Meyer-leon, Esq.IPLegal Strategies Group P.C.

20090061533 - Structure, target substance detection element and target substance detection kit: A target substance detection element that can effectively prevent the nonspecific adsorption of a target substance or impurities and detects the target substance with high sensitivity, a target substance detection kit, and a structure constituting the target substance detection element. The structure has a substrate, polymers present on the substrate... Agent: Fitzpatrick Cella Harper & Scinto

20090061536 - Si/si3n4 system nanosized particles, biosubstance labeling agent employing the nanosized particles, and method of manufacturing the nanosized particles: An objective is to provide Si/Si3N4 system nanosized particles each exhibiting reduced environmental load together with minimized bio toxicity, excellent chemical stability, enhanced relative light emission intensity, and less degradation of emission intensity during continuous exposure to light; a biosubstance labeling agent capable of keeping on labeling a biosubstance exhibiting... Agent: Cantor Colburn, LLP