Chemistry: analytical and immunological testing inventions 03/08

20080070310 - Methods for increasing the fermentability of plant material to yield ethanol: The present disclosure provides methods for increasing fermentability to yield ethanol from plant material by contacting the material with an effective amount of a protease to hydrolyze at least a portion of zein proteins. The present disclosure also provides methods for increasing digestibility of a milling co-product by contacting a... Agent: Harness, Dickey & Pierce, P.L.C

20080070311 - Microfluidic flow cytometer and applications of same: A flow cytometer. In one embodiment the flow cytometer includes a microchannel structure adapted for transporting a fluid medium containing one or more types of particles; means for generating electrokinetically microfluidic flows to transport the fluid medium in the microchannel structure so as to differentiate the one or more types... Agent: Morris Manning Martin LLP

20080070307 - Temperature history indicator: A temperature history indicator equipped with an oxygen detecting agent main body which changes in color in response to the oxygen concentration and a slightly gas-permeable packaging film for sealing and coating said oxygen detecting agent main body. The packaging film is a laminated film of two or more kinds... Agent: The Webb Law Firm, P.C.

20080070308 - Portous article for delivering chemical substances: A reagent delivering article capable of retaining liquid reagents, a method of pre-paring said articles and the use of said articles for loading liquid reagents is provided. Furthermore a reagent delivering article loaded with at least one liquid reagent, a method of preparing same and the use of said loaded... Agent: Morgan Lewis & Bockius LLP

20080070309 - Solution for calibrating a chemical analyzer for alcohol, carbonate and ammonia assays: A multi-analyte calibration solution having known amounts of sodium carbonate, ammonium bicarbonate, and ethyl alcohol, with pH adjusted within a range between about 7.8 and 8.4.... Agent: Dade Behring Inc. Legal Department

20080070312 - Antibodies against an extracellular matrix complex and their use in the detection of cancer: A method for assaying for cancer in a mammal. The method comprises attaching a trapping antibody to a surface, wherein the trapping antibody recognizes extracellular matrix (ECM) complexes. A biological fluid sample is contacted with the trapping antibody attached to the surface to thereby bind any ECM complex present in... Agent: Kirkpatrick & Lockhart Preston Gates Ellis LLP

20080070313 - Device for and method of testing occult blood in feces: The presence of occult blood in feces is detected using device comprising a liquid tight packet containing a sheet of absorbent material impregnated with a liquid solution that reacts with feces to produce a color change when blood is present. The packet is opened manually by tearing the packet apart... Agent: John J. Connors Connors & Associates, Inc.

20080070315 - Differentiation of cardiac and pulmonary causes of acute shortness of breath: The present invention relates to a method for differentiating in a subject suffering from acute shortness of breath (dyspnea) between (i) a pulmonary disease, (ii) a cardiovascular complication, (iii) a cardiovascular complication accompanied by a pulmonary disease or (iv) acute dyspnea without cardiovascular or pulmonary causes comprising the steps of... Agent: Roche Diagnostics Operations Inc.

20080070314 - Method and apparatus for identifying proteins in mixtures: A system and method for mass analysis where a sample (102) is separated in a liquid chromatograph (104), and subsequently analyzed in a mass spectrometer (112).... Agent: Paul, Hastings, Janofsky & Walker LLP

20080070316 - Chemical sensors comprising aniline polysiloxanes as sensitive materials and use thereof for detecting of assaying nitro compounds: The invention relates to chemical sensors comprising aniline-grafted polysiloxanes as sensitive materials, and to the use thereof for detecting or assaying nitro compounds, in particular nitroaromatic compounds. Fields of application detecting explosives, checking and monitoring atmospheric pollution and the quality of the ambient air in relatively confined spaces, monitoring of... Agent: Oblon, Spivak, Mcclelland Maier & Neustadt, P.C.

20080070318 - Method of specimen analysis and specimen analyzer: A novel method of specimen analysis in which prior to specimen analysis, any interfering substance can be measured. There is provided a method of specimen analysis, comprising the steps of irradiating a specimen with light to thereby obtain an optical information on the specimen from the specimen; mixing the specimen... Agent: Sughrue Mion, PLLC

20080070317 - Quantitative dual-dye photometric method for determining dilution impact: The invention provides ways to determine the impact of diluting a solution wherein the diluting may be carried out for any of a variety of purposes. In one embodiment, the method enables accurate volume dispensation calculations independent of meniscus shape. In another embodiment, the method enables accurate determination of plate... Agent: Chris A. Caseiro

20080070319 - Fluorescent polymer fine particle set, fluorescence detecting complex member set, fluorescent polymer fine particle composition and fluorescence detecting method: The invention provides a fluorescent polymer fine particle set including at least a first fluorescent polymer fine particle including a polymer fine particle having a core-shell configuration formed by a hydrophobic core and a hydrophilic shell, and a first fluorescent lanthanoid dye incorporated in the polymer fine particle and containing... Agent: Sughrue Mion, PLLC

20080070320 - Fluorescent chemical sensor: A method of detecting organic vapors is described. More particularly, the method involves the use of an analyte sensor that contains a polymeric material having a relatively large intrinsic porosity and that is capable of fluorescence in the visible region of the electromagnetic spectrum. The method further includes exposing the... Agent: 3m Innovative Properties Company

20080070321 - Beta-benzyloxyaspartic acid derivatives having two substituents on their benzene rings: The present invention provides a β-benzyloxyaspartic acid derivative having two substituents on its benzene ring, wherein the derivative has L-glutamate uptake inhibitory effect. More specifically, the present invention provides a compound of Formula (1) having an inhibitory effect against the glutamate uptake activity of L-glutamate transporters (wherein R1 represents an... Agent: Drinker Biddle & Reath (dc)

20080070322 - Optical microscopy with phototransformable optical labels: First activation radiation is provided to a sample that includes fluorescent proteins (“FPs”) to activate a first subset of the FPs in the sample. First excitation radiation is provided to the first subset of FPs in the sample to excite at least some of the activated FPs, and radiation emitted... Agent: Brake Hughes Bellermann LLP

20080070323 - Optical microscopy with phototransformable optical labels: An apparatus includes a position-sensitive detector to detect intensities of radiation as a function of position on the detector, and an optical system, characterized by a diffraction-limited resolution volume, adapted for imaging light emitted from activated and excited phototransformable optical labels (“PTOLs”) in a sample onto the position sensitive-detector. A... Agent: Brake Hughes Bellermann LLP

20080070324 - Quantity control device for microscope slide staining assays: A quality control device for microscope slide staining assays and method of use are provided for assessment of the quality of reagents and the assay process of immunohistochemical, in situ hybridization, histochemical, and chromogenic assays. The quality control device includes multiple control compounds, each is immobilized on a plurality of... Agent: Yi Li

20080064109 - Storage medium storing a game program, game apparatus, and game controlling method: A game system includes a game apparatus and a controller. The controller is furnished with an acceleration sensor for detecting accelerations in at least two axis directions. Game processing corresponding to the kind of an acceleration input by means of the controller is executed. For determining the kind, reference timing... Agent: Nixon & Vanderhye, P.C.

20080064114 - Genomic morse code: b) after spreading of the macromolecule to test on which the probes obtained in step a) are bound, detection of the position one compared to the others of the probes bound on the linearized macromolecule, the detection of the signature of a domain of interest indicating the presence of said... Agent: Foley And Lardner LLP Suite 500

20080064108 - Urine preservation system: An improved method of preserving a molecule in a bodily fluid comprises: (1) providing a preservative solution comprising: (a) an amount of a divalent metal chelator selected from the group consisting of ethylenediaminetetraacetic acid (EDTA), (ethylenebis(oxyethylenenitrilo))tetraacetic acid (EGTA), and 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid (BAPTA) and salts thereof in the range of from... Agent: Baker Botts L.L.P. Patent Department

20080064110 - System for purification and analysis of radiochemical products yielded by microfluidic synthesis devices: The present application is generally directed to microfluidic devices and methods for the achievement and assessment of chemical and radiochemical purity of (microfluidic) radio-synthesis products. More particularly, the current application relates to systems for purification and analysis of radiochemical products yielded by microfluidic synthesis devices.... Agent: Siemens Corporation Intellectual Property Department

20080064111 - Methods for diagnosing a gastrointestinal disorder in an individual: Methods for measuring at least one mucosally released neuroendocrine gut system component in an individual and methods for diagnosing a gastrointestinal disorder in an individual based on the concentration of at least one mucosally released neuroendocrine gut system component, and/or the ratio of the concentrations of at least one mucosally... Agent: Dinsmore & Shohl, LLP

20080064112 - Method for performing a non-invasive blood gas test: A non-invasive blood gas test is carried out by a method that utilizes a venous blood sample together with a pulse oximeter and a plurality of mathematical equations. The method generates the following data points of the blood: (i) the pH level; (ii) the [H+] concentration; (iii) the [HCO3—] concentration;... Agent: Ernest D. Buff Ernest D. Buff And Associates, LLC.

20080064113 - Methods and compositions for highly sensitive detection of molecules: Disclosed are methods, kits, and compositions for the highly sensitive detection of molecules. The methods, kits, and compositions are useful in determining concentrations of molecules in samples to levels of 1 femtomolar, 1 attomolar, or lower. The methods, kits, and compositions also allow the determination of concentration over a wide... Agent: Wilson Sonsini Goodrich & Rosati

20080064115 - Method for solid-phase-micro extraction and apparatus therefor: The present invention is directed to a system for pre-treatment of a sample to be introduced in a chromatograph, and a method for performing solid-phase extraction of a component present in a sample. The system uses a syringe having a needle being provided with a porous body having a monolithic... Agent: Hahn Loeser & Parks, LLP

20080064116 - Aqueous solution for use as medium for the specific binding reaction of a binding pair: The present invention refers to an aqueous solution for use as medium for the specific binding reaction of a binding pair, wherein a first binding member recognises its complementary second binding member. The solution contains a) a buffer to control pH; b) a compound A selected from a compound defined... Agent: Knobbe Martens Olson & Bear LLP

20080064117 - Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents: Provided are methods and compositions for assaying for ubiquitin agents that are enzymatic components of ubiquitin-mediated proteolysis and, more particularly, methods and compositions for assaying for agents that modulate the activity of such ubiquitin agents.... Agent: Klarquist Sparkman, LLP

20080064118 - Bioinformatic approach to disease diagnosis: (c) performing a receiver operating characteristic (ROC) regression or alternative regression technique of the score function using those tests and β coefficients calculated simultaneously to maximize the area under the curve (AUC) of the function and chosen simultaneously to generate the largest area below that portion of the ROC curve... Agent: Synnestvedt Lechner & Woodbridge LLP

20080064119 - Rapid diagnostic test systems and methods: A rapid diagnostic test system includes a lateral-flow strip for performing a binding assay. The lateral-flow strip contains a binding agent having a deposition density that varies periodically along at least a portion of the lateral-flow strip. The test system further includes an imaging system that is used to capture... Agent: Agilent Technologies Inc.

20080064120 - Raman spectroscopic lateral flow test strip assays: The invention provides improved Raman spectroscopy-based methods and systems for the quantitative analysis of selected analytes using lateral flow binding assay test strips.... Agent: Patton Boggs LLP

20080064122 - Intraplexing method for improving precision of suspended microarray assays: A method for making suspended microarray readings from a single sample statistically significant in a reliable manner. It can be applied to any assay system that uses discrete particles where the particles are coupled with an assay. Most of these systems suspend the particles in fluid and read the assay... Agent: Mathew J. Temmerman

20080064121 - Peptide-coated nanoparticles with graded shell compositions: A peptide-coated nanoparticle that includes a nanocrystal core surrounded by a graded shell that is composed of at least two different semiconductor molecules. At least one peptide is attached to the surface of the graded shell to render the nanoparticle biocompatible. The nanocrystal core and graded shell are optionally annealed... Agent: Venable LLP

20080064123 - Method of assaying antigen and reagent therefor: A latex agglutination method by which the measurement range is extended and the sensitivity of the measurement in the low concentration range is increased, is disclosed. The method for measuring a test antigen by latex agglutination uses two types of large and small particles, having different average particle sizes. Each... Agent: Birch Stewart Kolasch & Birch

20080057586 - Fluorescent cartridge for calibration of a microarray reader: An optically clear, fluorescent acrylic adapted for use as a calibration material. In particular, the fluorescent acrylic cartridge may used as a calibration tool for a microarray reader, such as, the Nanogen NC400® microarray system.... Agent: O''melveny & Myers LLP Ip&t Calendar Department La-1118

20080057587 - Fast metabolic imaging of systems with sparse spectra using spiral csi: A method of imaging the individual components of systems with sparse spectra using magnetic resonance imaging including the steps of a) exciting nuclei of labeled components using a MRI pulse sequence, b) selecting a proper spectral window to avoid/minimize signal overlap of aliased frequency components. In step a) preferably a... Agent: Beyer Weaver LLP

20080057588 - Method for the measurement of water and water-soluble components in non-aqueous liquids: A method for assigning a grade to a liquid hydrocarbon fuel in relation to the potential for a water or water-based phase to form is provided, comprising sensing the electrical resistance and the capacitance of the fuel, determining the amount of water or water-soluble compounds in the fuel based on... Agent: Birch Stewart Kolasch & Birch

20080057589 - Method for determining the presence of a chemical compound which is homogeneously distributed in a medium by means of cross-correlating a measuring spectrum with reference spectra: in which K(δλ,c′,c) denotes the correlation depending on the relative shift δλ of the functions I′(λ,c′) and I(λ,c) and the concentrations c′ and c of the at least one chemical compound V′ and V, c′ denotes the concentration of the at least one chemical compound V′ homogeneously distributed in the... Agent: Oblon, Spivak, Mcclelland Maier & Neustadt, P.C.

20080057590 - Markers associated with arteriovascular events and methods of use thereof: Disclosed are methods of identifying subjects with arteriovascular disease, subjects at risk for developing arteriovascular disease, methods of differentially diagnosing diseases associated with arteriovascular disease from other diseases or within sub-classifications of arteriovascular disease, methods of evaluating the risk of arteriovascular events in patients with arteriovascular disease, methods of evaluating... Agent: Mintz Levin Cohn Ferris Glovsky & Popeo

20080057591 - Metal indicator: s

20080057593 - Method for the prediction, diagnosis and differential diagnosis of alzheimer's disease: Methods are provided for the prediction, diagnosis and differential diagnosis of Alzheimer's disease. More particularly, a method is provided to determine whether a subject that does not show any clinical signs of Alzheimer's disease has a likelihood to develop Alzheimer's disease. Further a method is provided for the diagnosis of... Agent: Howrey LLP

20080057592 - Method of analyzing protein structure affinity relationship: A method for analyzing a structural affinity relationship between plural kinds of proteins and a compound, comprising the steps of (a) using a compound-immobilized carrier to purify plural kinds of proteins bound to the compound on the carrier, from a group of isotope-labeled proteins; (b) using a compound-immobilized carrier to... Agent: Dickstein Shapiro LLP

20080057594 - Waveguide and assay: A fluidic waveguide comprising a container and a fluid that fills said container, wherein said fluid has a refractive index greater than the refractive index of the wall of said container and wherein said fluid can act as a waveguide for electromagnetic radiation when contacted therewith is disclosed. A corresponding... Agent: Greenlee Winner And Sullivan P C

20080057595 - Method and device for the determination of several analytes with simultaneous internal verification in a graphical combination: The invention relates to a device in which molecules capable of reacting with analytes that are to be detected are immobilized on a surface such that said analytes are bound and can be detected in a subsequent reaction or in several reaction steps. According to the invention, at least two... Agent: Connolly Bove Lodge & Hutz, LLP

20080057596 - Colorimetric determination of somatic cell count in milk: The invention involves using a simple colorimetric method for a quantitative test to measure white blood cells in milk samples. The invention includes a new reagent system, a new analysis method, and a new apparatus which permits in-line colorimetric analysis.... Agent: Donald C. Simpson

20080057597 - Fat collection and preparation system and method: System and methods for collecting and preparing fat for autologous fat tissue transplantation. The system includes syringes, filtering and transferring assemblies coupled with the syringes, a centrifuge and a centrifuge insert releasably coupled with the centrifuge. Substances, including oil, fat, and denser substances, such as tumescent fluid, connective tissue, hormones... Agent: Patzik, Frank & Samotny Ltd.