Chemistry: analytical and immunological testing inventions 09/07

20070224690 - Varenicline standards and impurity controls: The subject invention provides a varenicline composition that comprises varenicline, or a pharmaceutically acceptable salt thereof, and an amount of a compound selected from one or more of several mononitro, monoamino, mixed aminonitro, diamino or dinitro intermediates, and the concentration of said compound is greater than 0 ppm and not... Agent: Pfizer Inc

20070224683 - Raman spectroscopic test strip systems: The invention provides diagnostic apparatuses that are advantageously adapted for the Raman spectroscopic analysis of fluid samples, such as biological fluid samples, deposited on test strip substrates. The tests strips may be include a surface-enhanced Raman spectroscopy (SERS) surface for deposition and analysis of a sample and/or may be lateral... Agent: Patton Boggs LLP

20070224684 - Transportable flow cytometer: A first preferred embodiment includes a flow cytometer with a fluidic system to draw a sample fluid into an interrogation zone, a light source to emit light toward the sample fluid in the interrogation zone, an optic system to collect and detect at least one of a scattered light and... Agent: Schox PLC

20070224685 - Reagent containing protease reaction promoter and/or colorant stabilizer: Provided are: a protease reaction promoter which is superior in usefulness to the known protease reaction promoters; a stabilizer for a colorant used for detection of an enzymatic reaction, and a method of stabilizing the colorant; and a reagent for and a method of measuring a glycated protein and a... Agent: Greenblum & Bernstein, P.L.C

20070224686 - Method for analyzing hemostasis: A method and device for blood hemostasis analysis is disclosed. A blood sample is displaced to reach a resonant state. The resonant frequency of the blood sample is determined before, during and after a hemostasis process. The changes in the resonant frequency of the blood sample are indicative of the... Agent: Marshall, Gerstein & Borun LLP

20070224687 - Analysis of large soil samples for actinides: A method of analyzing relatively large soil samples for actinides by employing a separation process that includes cerium fluoride precipitation for removing the soil matrix and precipitates plutonium, americium, and curium with cerium and hydrofluoric acid followed by separating these actinides using chromatography cartridges.... Agent: Mcnair Law Firm, P.A.

20070224689 - Method for predicting or identifying the onset of premature membrane rupture during pregnancy: A diagnostic test kit for simultaneously detecting the presence of amines (e.g., putrescine, cadaverine, tyramine, and trimethylamine) and C-reactive protein in a vaginal sample is provided. The test kit includes a lateral flow assay device containing a chromatographic medium (e.g., porous membrane, fluidic channel, etc.). The chromatographic medium defines a... Agent: Dority & Manning, P.A.

20070224688 - Peptide or protein-capturing surfaces for high throughput maldi mass spectrometry: Methods and compositions useful for capturing proteins or peptides from a sample mixture and analyzing the captured proteins or peptides via high throughput electrospray ionization (ESI) or matrix-assisted laser desorption/ionization mass spectrometry (HT MALDI MS) are provided. The methods and compositions are useful in large scale, simultaneous analyses of proteins... Agent: Corning Incorporated

20070224691 - Composition for measuring concentration of residual chlorine: t

20070224692 - Method and apparatus for detecting water in a fluid media: An apparatus and method for measuring the concentrations of oil, water and/or hydrates in a multiphase production fluid flow comprises measuring the complex permitivities, both real and imaginary parts, of the flow at at least two frequencies. One dispersive and one non-dispersive frequency are used. In one embodiment at least... Agent: Paul S Madan Madan, Mossman & Sriram, PC

20070224693 - Interlocked hydrogen source for gas chromatography: A gas chromatograph uses hydrogen carrier gas supplied by a hydrogen source. At least one hydrogen sensor monitors the hydrogen level. The gas chromatograph communicates with the hydrogen source over a communication link. When the sensed hydrogen level exceeds a threshold, the gas chromatograph signals the hydrogen source to stop... Agent: Agilent Technologies Inc.

20070224694 - Method and system for hyperspectral detection of animal diseases: An entirely new application for hyperspectral data has been identified as well as an entirely new means to detect TSE related diseases. This application can be applied to any disease where foreign matter builds in an observable location such as central nervous system tissue (retinal nerves). By using imagable central... Agent: Holland & Knight LLP

20070224695 - Chemoselective fluorgenic molecular linkers and methods for their preparation and use: The present invention describes a bioconjugation strategy and compounds that are useful therein in which a fluorescent signal is produced when two molecular or supramolecular entities are linked by chemoselective combination of one linker having an azido or halide substituent group with another linker having a cyano or an alkyne... Agent: Nelson Mullins Riley & Scarborough, LLP

20070224698 - System and method for direct digitization of nmr signals: A magnetic resonance imaging (MRI) system includes a transmitter that produces an RF excitation pulse that is applied to a subject positioned in the MRI system to induce emission of at least one of an NMR signal and an ESR signal therefrom, and that produces a reference signal indicative of... Agent: Quarles & Brady LLP

20070224697 - Means and method for analyzing samples by mass spectrometry: Disclosed is an improved method for performing a mass spectrometric analysis of a sample. More specifically, the present invention provides a method wherein analyte is transferred in a spatially coherent manner from a sample to the surface of a semiconductor. Laser light is used to produce gas phase ions directly... Agent: Law Offices Of Paul E. Kudirka

20070224696 - Metabonomic methods to assess health of skin: The present invention relates to methods of assessing the health of skin. Biomarkers are used to evaluate skin samples. Using metabonomics approaches, samples taken from different skin sites or at different times during a treatment are used to diagnose skin conditions or to appraise various skin treatments for efficacy.... Agent: The Procter & Gamble Company Intellectual Property Division - West Bldg.

20070224699 - X-ray visualizer, laser-beam operated micro-dissector, automated tissue processor: This invention employs the X-ray examination of tissue rather than gross examination from the human naked eye, which may be less exact than the more fine detailed analysis that may be gained through an X-ray system. Selection of more precise tissue sampling for microscopy without exhausting small biopsies can be... Agent: Jackson Lavale Gates, Md

20070224700 - Method and apparatus for analyzing bioprocess fluids: Methods and apparatus for analyzing bioprocess fluids are provided. A plurality of particles coated with a plurality of capture agents having an affinity for one or more biological markers is combined with bioprocess fluid to form a plurality of analyte-particle complexes. The system also includes a transport arrangement for transporting... Agent: Proskauer Rose LLP

20070224702 - Flex method: A method for quantifying n different analytes that are present in one or more liquid samples by performing n different affinity assay formats, each of which is dedicated for a particular one of the analytes. The characteristic feature is that each format is performed in a separate microchannel structures of... Agent: Fulbright & Jaworski, LLP

20070224701 - Combination vertical and lateral flow immunoassay device: The invention relates to immunoassays that detect the presence or absence, or determine the amount present of a particular analyte. More specifically, the invention relates to multizone, multilayered immunoassay test devices that utilize a combination of vertical and lateral flow to detect an analyte of interest.... Agent: David W. Highet, Vp And ChiefIPCounsel Becton, Dickinson And Company

20070224704 - Protein splice variant / isoform discrimination and quantitative measurements thereof: The invention relates to methods, reagents and apparatus for detecting protein isoforms (e.g., those due to alternative splicing, or different disease protein isoforms or degradation products) in a sample, including using combinations of capture agents, each combination being unique to the splicing variant to be detected/measured.... Agent: Goodwin Procter LLP Patent Administrator

20070224703 - Rapid determination of hepatocyte growth factor (hgf) in the body fluids: A method for diagnosing an inflammatory disorder in an individual comprises contacting a body fluid sample from the individual with an immunoassay device to determine relative levels of different forms of hepatocyte growth factor (HGF) in the sample, and correlating the determined levels to an inflammatory disorder. An immunoassay device... Agent: Dinsmore & Shohl, LLP

20070224705 - Method for detecting target compound: According to an aspect of the invention, there is provided a method for detecting a target compound including: injecting a test liquid containing a target compound into a colloid solution of magnetic nano-particles having an average particle diameter of 50 nm or less to allow the target compound to bind... Agent: Buchanan, Ingersoll & Rooney PC

20070218556 - Measuring nutrients in plants and soils by laser induced breakdown spectroscopy: A process for analyzing the nutrient status of plant matter and/or soil for one or more nutrients selected from among calcium, potassium, nitrogen, sulfur, phosphorus, magnesium, chlorine, iron, boron, manganese, zinc, copper, nickel and molybdenum is described and includes contacting said plant matter and/or soil with a laser source capable... Agent: Los Alamos National Security, LLC

20070218558 - Reference control composition containing a nucleated red blood cell component made of non-nucleated blood cells: A reference control composition containing a nucleated red blood cell component and the method of making are disclosed. The reference control composition includes a nucleated red blood cell component made of fixed non-nucleated blood cells and a suspension medium. The non-nucleated blood cell has a natural cell size substantially similar... Agent: Beckman Coulter, Inc.

20070218557 - Test element and method for testing blood: A test for diagnostic tests. particularly for testing blood prior to a transfusion is disclosed. The test element comprises at least two test units for carrying out at least two tests. The test element is provided with a fixing means for fixing said test element.... Agent: Ratnerprestia

20070218559 - Method for performing a non-invasive blood gas test: A non-invasive blood gas test is carried out by a method that utilizes a venous blood sample together with a pulse oximeter and a plurality of mathematical equations. The method generates the following data points of the blood: (i) the pH level; (ii) the [H+] concentration; (iii) the [HCO3—] concentration;... Agent: Ernest D. Buff Ernest D. Buff And Associates, LLC.

20070218560 - Methods, mixtures, kits and compositions pertaining to analyte determination: This invention pertains to methods, mixtures, kits and compositions pertaining to analyte determination by mass spectrometry.... Agent: Applied Biosystems

20070218561 - Analysis of amino acids in body fluid by liquid chromatography-mass spectrometry: A method for detecting amino acids in body fluids is described. The method includes derivatizing the body fluid amino acids (e.g. plasma amino acids), separating the derivatized amino acids by liquid chromatography followed by and subjecting the identification by mass spectrometry. The identity of each amino acid from the body... Agent: Foley & Lardner LLP

20070218562 - Color indicator for halamine treated fabric: The invention relates to a halamine compound indicator comprising a halamine compound treated substrate and a redox color indicating composition disposed on a selected area of the substrate, wherein the redox color indicator comprises a compound capable of reacting with the halamine compound and exhibiting color change as a result... Agent: Legal Department (m-495)

20070218563 - Stiochiometrically defined dye-labelled substances for measuring glomerular filtration rate, the production thereof and their use: The invention concerns new chemical compounds that can be used as marker substances in renal diagnostics, their production and use, and renal diagnostic agents which contain them.... Agent: Dinsmore & Shohl, LLP One Dayton Centre

20070218564 - Use of a composite or composition of diamond and other material for analysis of analytes: The present invention relates to the use of composites or compositions of diamond/non-diamond material, e.g. diamond/non-diamond carbon material for chemical or biological analysis. The invention further relates to the use of this material in separation adherence and detection of chemical of biological samples. Applications of either structurized substrates or mixed... Agent: Philips Intellectual Property & Standards

20070218565 - Method to detect ige: The present invention includes a method to detect IgE using a human Fc epsilon receptor (FcεR) to detect IgE antibodies in a biological sample from a cat, a dog, or a horse. The present invention also relates to kits to perform such methods.... Agent: Heska Corporation Intellectual Property Dept.

20070218566 - Method and device for improved purification of a substance bound to paramagnetic microparticles: The invention relates to a method for improved cleaning of a first substance which is bound to paramagnetic microparticles. Said microparticles are suspended in a first liquid. The inventive method comprises the following steps: a) microparticles are exposed to a first magnetic field in a first container so that they... Agent: Fish & Richardson P.C.

20070218567 - Sensing method for biopolymers and sensing device therefor: The present invention provides a highly sensitive sensing method for biopolymers and a sensing devise therefor by amplifying the magnetic signal generated from a biopolymer reaction. The invention concerns a sensing method for biopolymers which detects the magnetic signal generated from a labeled biopolymer under AC magnetic field using thermo-responsive... Agent: Oblon, Spivak, Mcclelland, Maier & Neustadt, P.C.

20070212784 - High speed sample supply device: Disclosed herein is a sample supply device that alternates between the supply of samples from one sample line while cleaning a second sample line and then supplying a second sample from the second sample line while cleaning the first sample line. This is repeated in rapid succession to allow greater... Agent: Knobbe Martens Olson & Bear LLP

20070212785 - Ims detection of chemical markers in petroleum products: A method and composition for identifying chemically tagged petroleum products can be achieved by adding one or more chemicals to a selected petroleum product wherein the chemical is immune to extraction from the petroleum product by conventional inexpensive absorbents, cannot be removed by extraction with acids, bases, or immiscible solvents,... Agent: Fish & Richardson P.C.

20070212786 - Monitoring heparin by microelectronic devices: In one aspect, the present invention provides a device and method for real-time, direct detection of heparin in buffer and in serum comprising a microfluidic field-effect device as an affinity biosensor. The sensor is based on an electrolyte-insulator-silicon structure, and is manufactured by a standard high-yield silicon microfabrication process. The... Agent: Choate, Hall & Stewart LLP

20070212787 - Method of quantitatively measuring trace amounts of metals in polymer samples: A method of quantitatively measuring trace amounts of metals in polymer samples using x-rays to fluoresce and detect metals that are present in the polymer sample is disclosed. The polymer sample is ground to a powder and formed into a thin film by heat and pressure. The film is then... Agent: Motorola, Inc.

20070212788 - Methods for detecting modulators of cytokine receptor zalpha11: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zalpha11, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can... Agent: Zymogenetics, Inc. Intellectual Property Department

20070212789 - Non-invasive method of determining oxygen concentration in a sealed package: The invention is a method of measuring oxygen concentration in a package having an oxygen sensitive product disposed therein. The method includes exposing a luminescent compound that is disposed in an interior of the package to light having a wavelength that is absorbed by the luminescent compound so that the... Agent: Alston & Bird LLP

20070212790 - Method for monitoring feeds to catalytic cracking units by near-infrared spectroscopy: A monitoring of catalytic cracking processing is provided which uses near infrared (NIR) analysis to characterize cracking feeds, intermediates and products for chemical and physical properties such as saturates, monoaromatics, diaromatics, triaromatics, tetraaromatics, polar aromatics, total aromatics, thiophenes, distillation points, basic nitrogen, total nitrogen, API gravity, total sulfur, MCRT and... Agent: Emch, Schaffer, Schaub & Porcello Co

20070212791 - Differential reflection spectroscopy system and method for detecting explosives and other target materials: A system and method for identifying explosive or other target materials includes the steps of irradiating a first location and a second location spaced apart from the first location from a sample suspected of including explosives with ultraviolet, visible or infrared light, measuring reflected light emanated from the first sample... Agent: Akerman Senterfitt

20070212793 - Fluorescent ion doped glass and method for using the fluorescent ion doped glass to enhance fluorescence imaging techniques: A fluorescent ion doped glass (or other fluorescing material) and a method for using the fluorescent ion doped glass to enhance a fluorescence imaging technique are described herein. In one embodiment, the fluorescent ion doped glass (or other fluorescing material) is used as a calibration standard to check the uniformity... Agent: Corning Incorporated

20070212792 - Method and apparatus for measuring oxygen concentration: f

20070212794 - Magnetic immunoassay system: A magnetic immunoassay system with a mechanism for compensating the direct current residual magnetic field in the vicinity of the specimen measurement position, in a direction perpendicular to the magnetic marker direction of magnetization for the measurement target. This invention reduces the effects of the magnetic field emitted from the... Agent: Stanley P. Fisher Reed Smith LLP

20070207547 - Scintillation proximity test: The invention concerns scintillation proximity assays performed in multiwell plates where a charge coupled device is used to image the wells. Conventional phosphors emit blue light (350-450 nm) which is absorbed by yellow or brown assay components. This problem is addressed by the use of phosphors that emit radiation of... Agent: Ge Healthcare Bio-sciences Corp. Patent Department

20070207549 - Method and apparatus for dna collection: A device for collection of DNA-containing materials is provided and a method of preventing DNA specimen contamination is provided which prevents extraneous DNA found in DNA evidence collection kits from interfering with DNA specimen analysis, further a device an method is provided for collecting the DNA-containing material of a subject... Agent: Shughart Thomson & Kilroy, PC

20070207548 - Microflow system for particle separation and analysis: A micro flow system is provided for separating particles, comprising a microfabricated member having a flow channel (5) defined therein for guiding a flow of a fluid containing the particles through the flow channel, first inlet means (2) positioned at one end of the flow channel for entering the fluid... Agent: Foley Hoag, LLP Patent Group (w/isa)

20070207550 - Accuracy improvement in blood gas testing: An improved bicarbonate determination with variability of apparent dissociation constant in Henderson-Hasselbach equation or Henderson equation with Henry's law is described. The improved bicarbonate is utilized in the determination of improved Base Excess, Base Deficit or Buffer Base for blood gas testing.... Agent: Dr. Amar Pal Singh Rana

20070207551 - Method for the assessment of particles and a system and device for use in the method: The present invention relates to a method and a device for the assessment of at least one parameter of particles in a liquid analyte material, comprising providing a device comprising a sample compartment comprising an exposing domain, an inlet through which a volume of a liquid sample representing the analyte... Agent: Jacobson Holman PLLC

20070207552 - Device for investigating chemical interactions and process utilizing such device: The invention relates to a device for investigating reactions between interactive species, said device comprising: one or more plasma deposited layers, which layers comprise one or more first pre-selected functional group species, which functional group species are interactible with a pre-selectable second species.... Agent: The Webb Law Firm, P.C.

20070207553 - High sensitivity biomolecule detection with magnetic particles: The present invention generally relates to the field of biomolecule detection. More specifically, the present invention relates to compositions, methods and systems for the detection and manipulation of biomolecules using magnetic particles.... Agent: John S. Fox

20070207554 - Medical system and method for determining parameters: The present invention discloses a device or system, and the method thereof, for determining gastrointestinal parameters with the reference database saved equations for calculating the parameters comprising concentration of dietary formula, the gastric residual volume, the amount of dietary formula retained in the stomach, and volume of dietary formula remaining... Agent: Whyte Hirschboeck Dudek S C

20070207555 - Ultra-sensitive detection systems using multidimension signals: Disclosed are compositions and methods for sensitive detection of one or multiple analytes. In general, the methods involve the use of special label components, referred to as multidimension signals. In the disclosed methods, analysis of multidimension signals can result in one or more predetermined patterns that serve to indicate whether... Agent: Wilmer Cutler Pickering Hale And Dorr LLP