Chemistry: analytical and immunological testing inventions 03/07

20070072298 - Reference control containing a nucleated red blood cell component: A method of making a reference control containing a nucleated red blood cell component includes providing a blood cell containing a nucleus; treating the blood cell with a treatment solution to alter a nucleus property from a natural value to a target value suitable for simulating nucleated red blood cells... Agent: Beckman Coulter, Inc.

20070072299 - Automatc analyzer: An automatic analyzer according to the invention can execute the re-measurement of a calibration or quality control sample easily when the measured data of the quality control sample is out of the reference range having maximum and minimum values set in advance. Accordingly, the automatic analyzer can quickly execute a... Agent: Mattingly, Stanger, Malur & Brundidge, P.C.

20070072300 - Methods of detection of iron deficiency and hemochromatosis: New diagnostic parameters or indexes for detection of absolute iron deficiency, latent iron deficiency, functional iron deficiency, or latent functional iron deficiency have been disclosed. The parameters include a RBC size factor, RSf1 defined by the formula of (MCV×MRV)1/2, or RSf2 defined by the formula of (MCV×MRV)/100, a volume-hemoglobin factor... Agent: Beckman Coulter, Inc.

20070072301 - Method for checking measurement result, system for checking measurement result, apparatus for checking measurement result, and storage medium: A system for checking measurement results is provided with a urine qualitative analyzer for measuring the specific gravity of a urine, urinary particle analyzer for measuring urine conductivity, and a computer. The urine specific gravity measured by the urine qualitative analyzer, and the urine conductivity measured by the urinary particle... Agent: Brinks Hofer Gilson & Lione

20070072302 - Method for quantitatively determining the ldl particle number in a distribution of ldl cholesterol subfractions: The invention provides a method (e.g., a computer algorithm) for calculating a number of particles in a LDL subfraction. The method features the steps of: 1) measuring an initial distribution of LDL particles (e.g., a relative mass distribution) from a blood sample; 2) processing the initial distribution of LDL particles... Agent: Mcdonnell Boehnen Hulbert & Berghoff LLP

20070072303 - Method of chromatographic analysis of a protein solution: An improved method of chromatographic analysis of protein samples is disclosed in which a Pluronic surfactant is used.... Agent: Oblon, Spivak, Mcclelland, Maier & Neustadt, P.C.

20070072304 - System and method for identifying biological growth media: A system and method for encoding and then identifying a growth media from among a plurality of different growth media. A method is disclosed that includes: providing a set of tagging agents that are distinct from each of the different growth media; adding to each different growth media a unique... Agent: Hoffman, Warnick & D'alessandro LLC

20070072305 - Composition for measuring residual chlorine concentration: To attain a composition for measuring residual chlorine concentration capable of preventing crystallization of a coloring reagent in a chemical solution under temperature conditions of 5° C., provided is a composition for measuring residual chlorine concentration in sample water including one or more coloring reagents selected from the group consisting... Agent: Birch Stewart Kolasch & Birch

20070072308 - Methods of forming monolayers of phage-derived products and uses thereof: Methods and compositions for identifying and characterizing the affinity of one or more ligands of a peptide are provided. In particular, a “stripped phage ligand sensor device” (SPLSD) is provided comprising a sensor coupled to a binding element of interest. Binding elements of the invention comprise phage which in most... Agent: Alston & Bird LLP

20070072307 - Methods of purifying fc region containing proteins: The present application provides methods of purifying polypeptides having a Fc region, for example, antibodies or antibody fusions, by adsorbing the polypeptides to a Fc binding agent, such as, for example, Protein A or Protein G, followed by a wash with a divalent cation salt buffer to remove impurities and... Agent: Lahive & Cockfield, LLP

20070072309 - Analytical compositions including nanometer-sized transducers, methods to make thereof, and devices therefrom: Disclosed is an analytical composition comprising a carrier coupled to an analytical transducer nanoparticle and a selector. Disclosed also are methods to make the analytical compositions. The analytical compositions are useful in detection and/or quantification of analytes, such as chemical compounds, biological species, and the like. The selector renders the... Agent: General Electric Company Global Research

20070065944 - Stabilizing griess reagent for explosives detection: The present invention provides a system wherein the Griess reagent has the ambient atmosphere removed. The present invention provides a system to treat the Griess reagent to improve storage lifetimes at room temperature or higher to over a year or more. The present invention greatly extends the useful lifetime of... Agent: Eddie E. Scott Assistant Laboratory Counsel

20070065945 - Method and apparatus for positioning a pipetting device: e

20070065946 - Method and device for the analysis of living reaction media: The invention relates to a method and device for the analysis of reaction media comprising one or more cells, which can be used to perform an automated high-throughput analysis.... Agent: Oblon, Spivak, Mcclelland, Maier & Neustadt, P.C.

20070065947 - Printing liquid solution arrays for inorganic combinatorial libraries: This invention provides methods and systems to prepare replicate arrays from master arrays of liquid solutions. Replicate arrays of liquid solutions can be reacted to form product solid inorganic material arrays for analysis and selection of optimum processes and products with desirable properties.... Agent: Quine Intellectual Property Law Group, P.C.

20070065948 - Use of antibody-surrogate antigen systems for detection of analytes: Compositions, methods and kits for labeling proteins and uses in reporter systems for detecting, quantifying and/or characterizing analytes.... Agent: Dechert LLP

20070065949 - Method and apparatus for desorption and ionization of analytes: This invention relates generally to methods and apparatus for desorption and ionization of analytes for the purpose of subsequent scientific analysis by such methods, for example, as mass spectrometry or biosensors. More specifically, this invention relates to the field of mass spectrometry, especially to the type of matrix-assisted laser desorption/ionization,... Agent: Townsend And Townsend And Crew LLP

20070065950 - Cell observation chamber: A biological cell observing chamber (30), wherein an intermediate support body (32) forming a skeleton outer shell structural part is mounted on a bottom support body (31) and a cover block body (33) is mounted on the bottom support body (31) on which the intermediate support body (32) is mounted... Agent: Bacon & Thomas, PLLC

20070065951 - Method for separating gaseous components from gaseous media and filter for performing the method: In a method for separating gaseous components from a gaseous medium, a gaseous medium is passed through at least one filter. The gaseous component contained in the gaseous medium is retained by reacting the gaseous component with at least one indicator present in the at least one filter. The at... Agent: Gudrun E. Huckett Draudt

20070065952 - Multi-directional immunochromatographic assays: Methods for quantitatively measuring the amount of one or more analyte(s) of interest in a fluid sample, and kits useful in the methods, are disclosed. The methods involve providing a solid phase apparatus comprising a membrane having an application point, a sample capture zone, and a control capture zone, where... Agent: Hamilton, Brook, Smith & Reynolds, P.C.

20070065953 - Methods for reducing the range in concentrations of analyte species in a sample: The present invention relates to the fields of molecular biology, combinatorial chemistry and biochemistry. Particularly, the present invention describes methods and kits for dynamically reducing the variance between analyte taken from complex mixtures.... Agent: Townsend And Townsend And Crew LLP

20070065954 - Surface plasmon resonance biosensor system for detection of antigens and method for determining the presence of antigens: The present invention provides an SPR system and corresponding methods of use, for determining the presence or concentration of tumor-associated antigens in cancer patient samples. The SPR system may have multiple channels, with each channel having operably affixed thereto an antibody specific for a tumor-associated antigen, so as to allow... Agent: Sughrue Mion, PLLC

20070059837 - Method for noticing changes in a package, method for locating a package, package and system for locating a package: The invention relates to a method non-damaging the package for noticing a change caused by a leakage, the oxygen content and/or deterioration of a product in the package by attaching an indicator to the packaging material using the dripping technique, which indicator indicates by discolouration a change in the conditions... Agent: Merchant & Gould PC

20070059838 - Dynamic constrained optimization of chemical manufacturing: System and method for chemical manufacture utilizing a dynamic optimizer for a chemical process including upstream and downstream processes. The dynamic optimizer includes a maximum feed calculator, operable to receive one or more local constraints on the downstream processes and one or more model offsets, and execute steady state models... Agent: Meyertons, Hood, Kivlin, Kowert & Goetzel, P.C.

20070059839 - Electronically controlled fluid limiting apparatus and method for use thereof: A flow control apparatus and method for operating the apparatus are disclosed. The flow control apparatus comprises a main supply line, a first valve, a first pressure transducer, a rotary meter, a control line, an intermediate valve, a second pressure transducer, a second valve, and a digital controller. The digital... Agent: Keeling Patents And Trademarks

20070059840 - Hemostasis analysis device and method: Apparatus for measuring hemostasis includes a container for holding a sample to be tested and a bobber configured to be buoyantly suspended on the sample. A magnet is secured to the bobber. A drive assembly is coupled to the container for driving the container in an oscillating motion. A magnetic... Agent: Marshall, Gerstein & Borun LLP

20070059841 - Electrochemiluminescence from acridan compounds: Methods are disclosed for producing electrochemiluminescence by electrochemically oxidizing an acridan compound at an electrode in the presence of a peroxide. Maintaining a sufficiently positive potential results in continuous oxidation of the acridan compound to an acridinium compound which reacts with peroxide to produce the luminescence. Light emission can be... Agent: Lumigen, Inc.

20070059842 - Mass analysis method and mass analysis apparatus: The invention provides a mass analysis method and apparatus capable of identifying proteins or peptides at greater speed and with improved accuracy. Specifically, a mass analysis method whereby a sample is ionized and a protein is analyzed using a mass analysis apparatus is provided, said method comprising: selecting predetermined information... Agent: Dickstein Shapiro LLP

20070059843 - Method of high-speed detection for biological analyte: This invention provides a method to detect analyte which comprises preparing fine particles which have a chargeable group in their core and a hydrophilic polymer chain in their shell; obtaining an agglutinated matter by forming a biologically specific bond between a specific residue on the surface of fine particles and... Agent: Wenderoth, Lind & Ponack, L.L.P.

20070059844 - Non-metameric color matching system and method: A pigment library and a method for preparing it are provided, which includes identifying a plurality of thermoplastic polymers and then selecting pigments useful in the plurality of thermoplastic polymers. The pigments are heat stable at the melt temperature of each of the plurality of thermoplastic polymers and are not... Agent: Novak Druce & Quigg, LLP

20070059845 - Reagents for the detection of protein phosphorylation in t-cell receptor signaling pathways: The invention discloses 95 novel phosphorylation sites identified in signal transduction proteins and pathways downstream of the T-cell receptor, and provides phosphorylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these phosphorylated sites/proteins, as well as methods of using the reagents for such... Agent: James Gregory Cullem, Esq. Intellectual Property Counsel

20070054402 - Stable isotopic identification and method for identifying products by isotopic concentration: A stable isotopic identification comprising a mathematical or numerical array of concentrations of isotopes found in a batched product, said mathematical or numerical array being presented in a machine readable form and comparable to analytical results whereby the product can be distinguished from other similar products, said machine readable form... Agent: David A. Lundy Krieg Devault Lundy LLP

20070054403 - Method of preventing white blood cell interferences to red blood cell measurements of a blood sample: Methods of prevention and correction of white blood cell interferences to the measurements of mean cell volume (MCV), red blood cell concentration (RBC) and hematocrit (Hct) of a blood sample are disclosed. The interference to MCV can be prevented by identifying a valley between the red blood cell and white... Agent: Beckman Coulter, Inc.

20070054404 - Method of hemoglobin correction due to temperature variation: A method of measuring a hemoglobin parameter of a test sample of blood comprises diluting and lysing a test sample. Then, a temperature corresponding to the test sample is obtained. The diluted and lysed test sample is then delivered to a cuvette, and a spectrophotometer determines the absorbance and/or transmittance... Agent: Beckman Coulter, Inc.

20070054405 - Patient sample classification based upon low angle light scattering: An apparatus for classifying a liquid patient sample includes at least one sample container having a quantity of a sample that is aggressively acted upon so as to create a flow field. A measurement mechanism includes at least one low angle light emitter aligned with a measurement window of the... Agent: Wall Marjama & Bilinski

20070054406 - Meter for rapid analysis of unbound zinc in liquids: Concentrations of free (or unbound, exchangeable, etc.) zinc in liquids can be rapidly measured by a metering device. The meter comprises an enclosure and frame, a receptacle that will hold cuvettes or other liquid sample holders, a light source with an activating (excitatory) wavelength, a photodetector to detect fluorescent emissions... Agent: Patrick D. Kelly Attorney For Applicant

20070054407 - Mass spectrometric analysis of ligand conjugated magnetic nanoparticles: The present invention provides methods, compositions, and systems for mass spectrometric analysis of magnetic nanoparticles displaying ligands on their surface. For example, the present invention provides methods of screening a sample for the presence of at least one analyte using ligand conjugated magnetic nanoparticles, magnetic separation, and mass spectrometric analysis.... Agent: Medlen & Carroll, LLP Suite 350

20070054408 - Microfabricated two-pin system for biomolecule crystallization: A two-pin liquid handling system for crystallizing biomolecules comprises a pair of interacting pins for holding a droplet of liquid therebetween. Each pin includes a tip spaced predetermined distance from the other pin to define a sample acquisition region. The two-pin liquid handling system includes a temperature and humidity control... Agent: Lahive & Cockfield, LLP

20070054409 - Urea concentration identification device for urea solution: A urea concentration identification device comprising a concentration identification sensor unit (2) and a support unit (4) attached at the bottom end thereof with this sensor unit and provided at the top end thereof with a mounting unit (4a) to a urea solution tank opening. The concentration identification sensor unit... Agent: Ronald R Santucci Frommer Lawrence & Haug

20070054410 - Dithio compounds: Disclosed herein are dithio compounds that include at least one fluorophore. The compounds additionally may include a different fluorophore or a non-fluorophore. The dithio compounds may be used as reagents for detecting thiol-containing compounds.... Agent: Foley & Lardner LLP

20070054411 - Method and system for detecting heterogeneities in mixing: A method for detecting mixing heterogeneities is provided. The method includes subjecting components of a sensitive chemical reaction to mixing conditions while illuminating the medium sufficiently to observe regions of heterogeneity resulting from insufficient mixing. A system for detecting mixing homogeneities is also provided.... Agent: Hoffmann & Baron, LLP

20070054412 - Oxidative dye composition and indicator: An oxidative dye solution comprises an indicating dye that has been reacted with a reducing agent. The pre-reacted dye when subjected to an oxidizing disinfection or sterilization agent such as peracetic acid or hydrogen peroxide under goes a visible color change and thus can serve as a chemical, process, or... Agent: Hudak, Shunk & Farine, Co., L.p.a.

20070054413 - Method for obtaining sample material: A sample carrier comprising a frame and one or more sample tube receiving structures pivotally connected to the frame. Each sample tube receiving structure includes a bottom member adapted to receive a plurality of sample tubes and a top member having a plurality of aligned apertures sized to receive sample... Agent: Gen Probe Incorporated

20070054414 - Device and methods for detecting an analyte in a sample: Disclosed is a device, for detecting an analyte in a sample, comprising a sample pad for collecting the sample, a test strip coupled to the sample pad, and a housing enclosing and allowing visualization of the test strip. The sample pad can include one or more markings for determining the... Agent: Townsend And Townsend And Crew, LLP

20070054416 - High density sample holder for analysis of biological samples: A sample holder comprises a substrate microfabricated to define a multiplicity of microscopic islands defining sample support surfaces. At least one sump separates adjacent island surfaces and inhibits transport of samples between adjacent island surfaces.... Agent: Kirkpatrick & Lockhart Nicholson Graham LLP

20070054415 - Method and apparatus for assay in utilizing attenuated total reflection: A surface plasmon resonance (SPR) assay apparatus is provided, in which a flow channel, a sensing surface and an optical assay unit are used. The sensing surface is associated with the flow channel, and contacted by a sample in the flow channel. The optical assay unit applies illuminating light to... Agent: Sughrue Mion, Pllc

20070054417 - Method and device for the detection of very small quantities of particles: The invention relates to a method and a device for detecting very small quantities of particles. The inventive method is based on a detection of antigen-antibody reaction products and provides a very high detection sensitivity all the way to the femtomolar or attomolar range.... Agent: John B Hardway Iii Nexsen Pruet Adams Kleemeier

20070054418 - Nanoporous organosilicas as pre-concentration materials for sensors: A molecularly imprinted material made from polymerizing a monomer having the structural formula (OR)3Si—B-A-B—Si(OR)3. A is a divalent organic group, B is a saturated or unsaturated divalent hydrocarbon group or a covalent bond, and R is an independently selected saturated or unsaturated monovalent hydrocarbon group. A preconcentrator having: a container... Agent: Naval Research Laboratory Associate Counsel (patents)

20070048866 - Paint for detection of radiological or chemical agents: A paint that warns of radiological or chemical substances comprising a paint operatively connected to the surface, an indicator material carried by the paint that provides an indication of the radiological or chemical substances, and a thermo-activation material carried by the paint. In one embodiment, a method of warning of... Agent: Eddie E. Scott Assistant Laboratory Counsel

20070048867 - Paint for detection of corrosion and warning of chemical and radiological attack: A system for warning of corrosion, chemical, or radiological substances. The system comprises painting a surface with a paint or coating that includes an indicator material and monitoring the surface for indications of the corrosion, chemical, or radiological substances.... Agent: Eddie E. Scott Assistant Laboratory Counsel

20070048868 - Monitoring method, monitoring apparatus, and liquid sample analyzer: A liquid sample is aspirated using an aspirating tube provided with a flow path extending lengthwise in the interior of the tube, and an aspiration orifice for aspirating the liquid sample formed near the tip of the tube. The aspiration of the liquid sample to the aspirating tube is monitored... Agent: Brinks Hofer Gilson & Lione

20070048869 - Valve system and deposition apparatus including valve system and atomic layer deposition chamber: A deposition apparatus includes an Atomic Layer Deposition (ALD) chamber, a system-control unit which generates a control signal, a solenoid valve which supplies air pressure in response to the control signal generated by the system-control unit, a gas line which supplies a process gas, an air pressure valve which opens... Agent: Volentine Francos, & Whitt PLLC

20070048870 - Endohedral fullerenes as spin labels and mri contrast agents: This invention pertains to the discovery that certain endohedral fullerenes are functional paramagnetic materials exhibiting increased relaxation times. These endohedral fullerenes provide improved labels for use in electron spin resonance (ESR) detection systems.... Agent: Quine Intellectual Property Law Group, P.C.

20070048871 - Methods and devices for measuring total polar compounds in degrading oils: This invention relates to methods for determining whether or not to discard a sample of oil based on the presence of polar compounds in the oil and devices to be used therewith. In a preferred embodiment a test strip comprising an adsorbent affixed to a backing is spotted with a... Agent: 3m Innovative Properties Company

20070048872 - High throughput screening of fatty acid composition: A method for the high throughput screening of fatty acid characteristics in seeds is provided. The method comprises feeding seeds individually to a sampling station; removing a sample from the seed in the sampling station; conveying the sample to a compartment in a sample tray; converting extracted oil from the... Agent: Harness, Dickey, & Pierce, P.l.c

20070048873 - Method of quantitative analysis of hexavalent chromium in chromate coating: A method of quantitative analysis of hexavalent chromium in a chromate coating includes immersing a substrate on which a chromate coating is formed in an aqueous solution containing lithium hydroxide to extract hexavalent chromium, and performing quantitative analysis of extracted hexavalent chromium.... Agent: Oblon, Spivak, Mcclelland, Maier & Neustadt, P.C.

20070048874 - Processing and analysis techniques involving in-vessel material generation: In at least one embodiment, the inventive technology relates to in-vessel generation of a material from a solution of interest as part of a processing and/or analysis operation. Preferred embodiments of the in-vessel material generation (e.g., in-vessel solid material generation) include precipitation; in certain embodiments, analysis and/or processing of the... Agent: Santangelo Law Offices, P.C.

20070048875 - Method and system for testing and controlling a custody of a fluid specimen: A system for automatically testing a fluid specimen, e.g., urine, to indicate the presence of specified chemical components in the specimen. The system preferably utilizes an assaying device comprised of a specimen container having a unique identifier thereon and a cap which carries at least one test strip. A method... Agent: Hovey Williams LLP

20070048876 - Visual spill indicating: Composition has an indicating dye encapsulated by an encapsulating material. An encapsulated indicating dye can be combined with an organic substance absorbent and/or adsorbent. The composition, combination and/or a device having one or both of them can be used to indicate the presence of an organic substance by contacting the... Agent: Christopher John Rudy

20070048877 - Method and device for preparing a biological sample for biological analyses: The method and devices are for preparing a biological sample for biological analyses. The biological sample has at least one amino acid sequence from an organism. The amino acid sequence is a subject of degradation. The biological sample is physically prepared to enable altering a secondary structure of the amino... Agent: Fasth Law Offices (rolf Fasth)

20070048878 - Diagnostic sanitary test strip: An improved multi-layered diagnostic sanitary test strip for receiving a heterogenous fluid, such as whole blood, to test for presence and/or amount of a suspected analyte in the fluid by facilitating a color change in the strip corresponding to the amount of the analyte in the fluid, wherein the test... Agent: Finnegan, Henderson, Farabow, Garrett & Dunner LLP