Chemistry: analytical and immunological testing inventions 09/06

20060211119 - Fuel cell leak detection: Methods and systems of facilitating detection of fuel leaks in a fuel cell system include adding organic molecules to a fuel cell fuel supply to odorize the fuel supply....

20060211120 - Techniques for analyzing products containing a coloring agent: A method is provided for detecting a tracer in a preparation by precipitating a coloring agent from a sample of the preparation, especially where the coloring agent otherwise interferes with detection of the tracer. A sample of the preparation may be contacted with an effective amount of a precipitating agent...

20060211121 - Determination of high lipophilicity values: The present invention relates to a novel method for determining the lipophilicity of a compound of interest comprising a) providing a layer, b) impregnating said layer with a solvent A, c) applying a dissolved compound of interest on the impregnated layer, d) adding a solvent B, e) removing the solvent...

20060211122 - Reagents for the measurement of peroxynitrites: wherein R1 represents an amino group, or hydroxy group; R2 represents a 2-carboxyphenyl group; and X1 and X2 independently represent hydrogen atom, or a halogen atom (e.g., 2-[6-(4′-hydroxy)phenoxy -3H-xanthen-3-on-9-yl]benzoic acid, or 2-[6-(4′-amino)phenoxy-3H-xanthen-3-on-9-yl]benzoic acid) or a salt thereof, which does not react with superoxide or nitrogen monoxide, a precursor of peroxynitrite,...

20060211123 - Sensing element and method of making: A sensing element and a method of making the same are provided. The sensing portion of the element comprises an inorganic binder and a sensing material. In some instances, the sensing material can be an ammonia sensing material....

20060211124 - Method for the determination of the caco3 content of a scrubbing liquid: The present invention relates to a method for the determination of the CaCO3, content of a scrubbing liquid, which has been separated from a scrubbing liquid circuit of a scrubbing column....

20060211125 - Electrolytic eluent generator: An acid or base is generated in an aqueous solution by the steps of: (a) providing a source of first ions adjacent an aqueous liquid in a first acid or base generation zone, separated by a first barrier (e.g., anion exchange membrane) substantially preventing liquid flow and transporting ions only...

20060211126 - Method for using texturing surfaces of optical fiber sensors for blood glucose monitoring: Disclosed is a method and the resulting product thereof comprising a solid light-conducting fiber with a point of attachment and having a textured surface site consisting a textured distal end prepared by being placed in a vacuum and then subjected to directed hyperthermal beams comprising oxygen ions or atoms. The...

20060211127 - Blood testing unit and blood testing method and apparatus: A blood testing unit comprises a closed vessel having a blood introducing section formed at a certain area of the closed vessel. A blood constituent separating section is located within the closed vessel to separate plasma and/or serum from the blood sample introduced through the blood introducing section into the...

20060211128 - Crude unit desalter emulsion level detector: The present invention is directed to a method for determining an emulsion layer within a container comprising, initiating an ultrasonic signal from at least one transmitter through a liquid contained within a tank, receiving the signal at a receiver, measuring the time of flight of the signal, calculating the velocity...

20060211129 - Real-time component monitoring and replenishment system for multicomponent fluids: A multicomponent fluid composition monitoring and compositional control system, in which a component analysis is effected by titration or other analytical procedure, for one or more components of interest, and a computational means then is employed to determine and responsively adjust the relative amount or proportion of the one or...

20060211130 - Method for continuous mode processing of multiple reaction receptacles in a real-time amplification assay: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations in which discrete aspects of the assay are performed on fluid samples contained in sample vessels. The analyzer includes stations for automatically preparing a sample, incubating the sample, preforming an analyte isolation procedure, ascertaining the presence of a...

20060211131 - Method for analysis of contaminants in a process fluid stream: The present invention relates to the monitoring of contaminant concentrations in manufacturing processes that employ fluid purification devices. The invention provides a sensitive method for analyzing contaminant concentrations in a process fluid stream using purification material to adsorb contaminants contained therein over an entire process....

20060211132 - Method for high throughput drop dispensing of specific patterns: The invention relates to methods and systems for high throughput precision “on-the-fly” dispensing of sub-microfluidic quantities of reagents and other liquids in specific patterns onto or into a target substrate. In certain embodiments, a high speed process is provided for creating and/or repeating spaced lines or line segments by dispensing...

20060211134 - Priming module for microfluidic chips: Methods and apparatuses for priming sample substrates such as DNA sipper chips are disclosed. According to one aspect of the present invention, a priming system that is suitable for priming a substrate which has a plurality of wells and at least one channel includes a base unit and a top...

20060211133 - Ultra-low volume fraction collection and analysis: An ultra-low volume fraction collection and concentration method provides practical application in collecting fractions, e.g. as low as 25 nL, from nanoLC columns into pipette tips at user-defined timed-intervals. The fractions are dried to create a concentrated band at the very end of the interior of the pipette tip and...

20060211135 - Method and apparatus for separating molecules using micro-channel: A method for simply and efficiently separating substances by utilizing a specific flow behavior in a non-turbulent flow, i.e. a laminar flow, in a micro-channel is disclosed. A mixed solution containing at least two kinds of solute molecules which are different from each other in molecular weight and/or molecular sharp,...

20060211137 - Biosensor: It is an object of the present invention to provide a biosensor wherein a reference unit and a measurement unit can be prepared by performing only a single operation for immobilizing a physiologically active substance and wherein unnecessary electric charge does not remain in the reference unit. The present invention...

20060211142 - Fibronectin and fibrinogen biopolymer markers indicative of insulin resistance: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060211143 - Fibronectin and fibrinogen biopolymer markers indicative of insulin resistance: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060211149 - Fibronectin and fibrinogen biopolymer markers indicative of insulin resistance: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060211150 - Fibronectin and fibrinogen biopolymer markers indicative of insulin resistance: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060211145 - Interalpha trypsin inhibitor biopolymer markers indicative of insulin resistance: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060211146 - Interalpha trypsin inhibitor biopolymer markers indicative of insulin resistance: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060211136 - Method for gold deposition: A method for depositing gold on a substrate is provided. By this aspect nucleation centers are bound, deposited or formed at one or more sites on the substrate, the substrate is then contacted with a treatment composition which comprises soluble gold-providing agent from which gold is deposited onto a nucleation...

20060211144 - Protein biopolymer markers indicative of age matched control: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060211147 - Protein biopolymer markers indicative of age matched control: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060211148 - Protein biopolymer markers indicative of age matched control: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060211138 - Protein biopolymer markers predictive of insulin resistance: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060211139 - Protein biopolymer markers predictive of insulin resistance: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060211140 - Protein biopolymer markers predictive of insulin resistance: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060211141 - Protein biopolymer markers predictive of insulin resistance: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060211151 - Methods for fabricating separation apparatus: Methods for fabricating sample separation apparatus include forming at least one elongate matrix in a solid substrate. The matrix, which may include pores, includes the same material as a nonporous substrate. A stationary phase may be applied to the matrix. Examples of stationary phases include, but are not limited to,...

20060205082 - Reaction rate determination: One embodiment of the invention provides a method for determining the rate of reaction by including sample points before initiation of the reaction. Absorbance measurements are taken over a plurality of time points, prior to initiation of the reaction, to obtain zero-time absorbance points. The sample is combined with a...

20060205083 - Photoelectrochemical determination of chemical oxygen demand: A method for determining chemical oxygen demand of a water sample comprises the steps of (a) applying a constant potential bias to a photoelectrochemical cell, having a photoactive working electrode (e.g. a layer of titanium dioxide nanoparticles coated on an inert conductive substrate) and a counter electrode, and containing a...

20060205084 - Methods of optimizing drug therapeutic efficacy for treatment of immune-mediated gastrointestinal disorders: The present invention provides a method of optimizing therapeutic efficacy and reducing toxicity associated with 6-mercaptopurine drug treatment of an immune-mediated gastrointestinal disorder such as inflammatory bowel disease. The method of the invention includes the step of determining the level of one or more 6-mercaptopurine metabolites in the patient having...

20060205085 - Processing particle-containing samples: A microfluidic device includes an input port for inputting a particle-containing liquidic samples into the device, a retention member, and a pressure actuator. The retention member is in communication with the input port and is configured to spatially separate particles of the particle-containing liquidic sample from a first portion of...

20060205088 - Agglutination assay method in porous medium layer: An agglutination assay method for quantitatively determination of an analyte in an aqueous liquid sample using particles bearing an anti-analyte. The agglutination is conducted in the porous medium layer of the analysis element A speedy quantitative analysis of the analyte can be conveniently attained with high sensitivity. When the particle-labeled...

20060205086 - Diagnostic device: A diagnostic device for testing a liquid sample has a carrier for receiving at least a portion of the sample and a sample delivery means. The sample delivery means has a delivery channel that is in fluid communication with the carrier. The delivery channel has a first delivery channel surface...

20060205087 - Lateral flow devices using reactive chemistry: There is provided a lateral flow assay device for detecting the presence or quantity of an analyte residing in a test sample where the lateral flow assay device has a porous membrane in communication with a wicking pad. The porous membrane has a detection zone which has a chromophore configured...

20060205089 - Mapping discontinuous antibody or aptamer epitopes for protein structure determination and other applications: The present invention is directed to methods of mapping antibody or aptamer epitopes for use in a variety of utilities including the elucidation of the tertiary structure of proteins. A method of the invention, antibody imprinting, uses antibodies or aptamers against target proteins and random peptide probe libraries to map...

20060205091 - Protein biopolymer markers predictive of insulin resistance: The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their...

20060205090 - Water-soluble conjugates for electrochemical detection: The present invention provides water-soluble conjugates and methods of using them in diagnostic and detection assays. Devices for performing detection and quantitation assays are also provided. In various embodiments the conjugates are useful in immunoassays and later flow assays. The invention provides methods of preparing the conjugates that result in...

20060205092 - Bioanalysis systems including optical integrated circuit: Optical Integrated Circuits (OIC) in Surface Plasmon Resonance (SPR) Analysis Systems combined with micorarray or microwell plates to provide enhanced sensitivity, stability, speed of analysis and reduced size are disclosed. Using the OIC with other optical analysis methods to provide enhance analysis systems is also disclosed....

20060205093 - Use of magnetic particles for determining binding between bioactive molecules: An assay as well as tools and apparatus therefore are disclosed for determining interaction between microbiological entities such as bioactive molecules using at least a first particle or microcarrier e.g. a bead, and a second particle which may also be a microcarrier, e.g. a second bead. At least the first...

20060205094 - Methods using novel chemiluminescent labels: Methods using chemiluminescent label compounds and chemiluminescent labeled conjugates are provided. The compounds comprise an acridan ring bearing an exocyclic ketene dithioacetal group and further contain a labeling substituent which permits attachment to compounds of interest. The novel chemiluminescent compounds and labeled conjugates are convenient to prepare, are highly stable,...

20060199267 - Apparatus for controlled venting of a chamber: The present invention provides apparatus and methods for adjusting the atmosphere within a substantially sealed chamber containing respiring produce. The chamber of the present invention includes inlet means to permit ambient atmosphere to enter the chamber, and outlet means to permit chamber atmosphere to exit the chamber. Methods using apparatus...

20060199268 - Method for assessing arteriosclerosis and diabetic nephropathy: A method for assessing arteriosclerosis comprising measuring the serotonin level in whole blood, serum or platelet-rich plasma and rating the serotonin level on such a scale that the lower it is, the more serious the arteriosclerosis is....

20060199269 - Method for assessing pyrimidine metabolism: A method is provided for determining pyrimidine metabolism of an individual. By collecting a saliva sample containing a concentration of a pyrimidine from an individual, the saliva sample can be measured for the pyrimidine to yield a pyrimidine measurement. Through the comparison of the pyrimidine measurement to a value measured...

20060199270 - Optical fiber based fluorescence sensor for in-situ measurement and control of fuel cells: The present invention provides, a system and method for unobtrusively determining water content within a fuel cell. One embodiment of a system in accordance with the present invention includes a fuel cell body including an ionomeric membrane, water and a fluorophore contained therein. The system further includes a medium for...

20060199271 - Temperature feedback control for solid state gas sensors: A solid state gas sensor may include gas sensing element coupled to a substrate. The gas sensing element may have a desired operating temperature, which may be between 100 and 400 degrees Celsius. The sensor may further include a temperature sensor coupled to the substrate and configured to sense an...

20060199272 - Compounds generating a dynamic nuclear polarisation process: The present invention relates to radicalas for use in a dynamic nuclear polarisation (DNP) of a sample. The invention further relates to a dynamic nuclear polarisation of a mixture comprising these radicals....

20060199274 - Atmosphere conditioning method, exposure apparatus, and device manufacturing method: A method is provided of conditioning an atmosphere inside a chamber of an exposure apparatus in which an optical element is disposed for directing light to expose a substrate. The method includes the steps of supplying inert gas into the chamber and exhausting gas from the chamber. The supplying step...

20060199273 - Method for arranging a polymer molecule: The invention relates to a method for arranging a polymer molecule such as a biomolecule on a support, the method comprising the following steps: providing a substrate (3) having a surface (2); providing a surface layer (4) on said surface (2) of the substrate (3), said substrate (3) and said...

20060199275 - Method and tool for filtrating specimen using specimen sampling container, and specimen sampling container: In collecting and filtrating the liquid sample using a sample collection vessel 1, in which a sample-collecting part 3 containing a filter member 4 is inserted in a vacuumed sample-storing part 2, the sample storing part 2 and sample-collecting part 3 are air-tightly sealed with a stopper 5, the liquid...

20060199276 - Device for multiple rapid detection and testing of diseases, disorders and immunity in human, animals and the environment: According to the invention there is provided a device for testing for diseases disorders and immunity in humans, animals and the environment, which includes a bottom membrane support assembly having a lower opening and operative to receive a bottom membrane extending over said lower opening and a top membrane support...

20060199277 - Devices and methods for analyte assays with built-in result reporting using recognizable symbols: The present invention provides devices, methods and kits for detecting the presence of an analyte in a liquid sample and indicating to the user the presence or absence of the analyte through the formation of a recognizable symbol during the assay. In one embodiment, the present invention provides test strips...

20060199278 - Double-sided device for multiplex dipstick immunodiagnostic: The present invention relates to methods and devices for detecting one or more analytes or analyte products in a biological sample. This invention in particular relates to improved rapid tests such as “dipsticks” and “lateral flow” devices. The invention in particular relates to chromatographic device made of two active sides,...

20060199279 - Methods for identifying post-translationally modified polypeptides: The invention provides methods of analyzing a sample. In general, the methods involve multi-dimensionally fractionating a sample to produce a set of sub-fractions, identifying a sub-fraction of interest by evaluating binding of a first portion of the sub-fractions to a binding agent; and analyzing the mass of analytes in a...

20060199280 - Quantification of proteins: The invention provides a method and kit for determining the quantity of certain proteins comprising post-translationally modified sulfhydryl groups. The invention also provides a method and kit for determining the quantity of a protein having no cysteines in its amino acid sequence....

20060199281 - Surfaces coated with target-induced fluorescent compounds for detection of target elements: Surfaces coated with a target-induced fluorescent compound are used to detect target elements, especially trace elements. The target-induced fluorescent compound does not fluoresce when excited at a specific wavelength until it has bound a target element. The use of these coated surfaces provides several benefits including reduced background for greater...

20060199267 - Apparatus for controlled venting of a chamber: The present invention provides apparatus and methods for adjusting the atmosphere within a substantially sealed chamber containing respiring produce. The chamber of the present invention includes inlet means to permit ambient atmosphere to enter the chamber, and outlet means to permit chamber atmosphere to exit the chamber. Methods using apparatus...

20060199268 - Method for assessing arteriosclerosis and diabetic nephropathy: A method for assessing arteriosclerosis comprising measuring the serotonin level in whole blood, serum or platelet-rich plasma and rating the serotonin level on such a scale that the lower it is, the more serious the arteriosclerosis is....

20060199269 - Method for assessing pyrimidine metabolism: A method is provided for determining pyrimidine metabolism of an individual. By collecting a saliva sample containing a concentration of a pyrimidine from an individual, the saliva sample can be measured for the pyrimidine to yield a pyrimidine measurement. Through the comparison of the pyrimidine measurement to a value measured...

20060199270 - Optical fiber based fluorescence sensor for in-situ measurement and control of fuel cells: The present invention provides, a system and method for unobtrusively determining water content within a fuel cell. One embodiment of a system in accordance with the present invention includes a fuel cell body including an ionomeric membrane, water and a fluorophore contained therein. The system further includes a medium for...

20060199271 - Temperature feedback control for solid state gas sensors: A solid state gas sensor may include gas sensing element coupled to a substrate. The gas sensing element may have a desired operating temperature, which may be between 100 and 400 degrees Celsius. The sensor may further include a temperature sensor coupled to the substrate and configured to sense an...

20060199272 - Compounds generating a dynamic nuclear polarisation process: The present invention relates to radicalas for use in a dynamic nuclear polarisation (DNP) of a sample. The invention further relates to a dynamic nuclear polarisation of a mixture comprising these radicals....

20060199274 - Atmosphere conditioning method, exposure apparatus, and device manufacturing method: A method is provided of conditioning an atmosphere inside a chamber of an exposure apparatus in which an optical element is disposed for directing light to expose a substrate. The method includes the steps of supplying inert gas into the chamber and exhausting gas from the chamber. The supplying step...

20060199273 - Method for arranging a polymer molecule: The invention relates to a method for arranging a polymer molecule such as a biomolecule on a support, the method comprising the following steps: providing a substrate (3) having a surface (2); providing a surface layer (4) on said surface (2) of the substrate (3), said substrate (3) and said...

20060199275 - Method and tool for filtrating specimen using specimen sampling container, and specimen sampling container: In collecting and filtrating the liquid sample using a sample collection vessel 1, in which a sample-collecting part 3 containing a filter member 4 is inserted in a vacuumed sample-storing part 2, the sample storing part 2 and sample-collecting part 3 are air-tightly sealed with a stopper 5, the liquid...

20060199276 - Device for multiple rapid detection and testing of diseases, disorders and immunity in human, animals and the environment: According to the invention there is provided a device for testing for diseases disorders and immunity in humans, animals and the environment, which includes a bottom membrane support assembly having a lower opening and operative to receive a bottom membrane extending over said lower opening and a top membrane support...

20060199277 - Devices and methods for analyte assays with built-in result reporting using recognizable symbols: The present invention provides devices, methods and kits for detecting the presence of an analyte in a liquid sample and indicating to the user the presence or absence of the analyte through the formation of a recognizable symbol during the assay. In one embodiment, the present invention provides test strips...

20060199278 - Double-sided device for multiplex dipstick immunodiagnostic: The present invention relates to methods and devices for detecting one or more analytes or analyte products in a biological sample. This invention in particular relates to improved rapid tests such as “dipsticks” and “lateral flow” devices. The invention in particular relates to chromatographic device made of two active sides,...

20060199279 - Methods for identifying post-translationally modified polypeptides: The invention provides methods of analyzing a sample. In general, the methods involve multi-dimensionally fractionating a sample to produce a set of sub-fractions, identifying a sub-fraction of interest by evaluating binding of a first portion of the sub-fractions to a binding agent; and analyzing the mass of analytes in a...

20060199280 - Quantification of proteins: The invention provides a method and kit for determining the quantity of certain proteins comprising post-translationally modified sulfhydryl groups. The invention also provides a method and kit for determining the quantity of a protein having no cysteines in its amino acid sequence....

20060199281 - Surfaces coated with target-induced fluorescent compounds for detection of target elements: Surfaces coated with a target-induced fluorescent compound are used to detect target elements, especially trace elements. The target-induced fluorescent compound does not fluoresce when excited at a specific wavelength until it has bound a target element. The use of these coated surfaces provides several benefits including reduced background for greater...