Chemistry: analytical and immunological testing inventions 06/06

20060141628 - High resolution flow cytometer: high resolution particle differentiation process and separation system that provides enhanced resolution of particles based upon selected particle characteristics. In particular, the system may include an enhanced resolution flow cytometer. In an embodiment, the invention can include at least one fluid source conduit (24) that introduces 0 fluid source stream...

20060141629 - Method and system for determining platelet-mediated clot formation: The present invention concerns methods for determining platelet medicated clot formation. Specifically, the invention provides a method for determining platelet-medicated clot formation in a blood sample comprising: (i) obtaining sample of blood, and optionally mixing same with an anti-coagulant in an amount effective to inhibit clot formation; (ii) in a...

20060141630 - Computerized method and apparatus for analyzing amino acids: A method for analyzing a plurality of amino acids in a fluid sample by a user is provided comprising the steps of introducing the sample into a buffer solution, passing the sample in the buffer solution through a separation column and setting a lithium ion concentration in the buffer to...

20060141631 - Quantitation of biological molecules: Methods and apparatus, including computer program products, for quantifying peptides in a peptide mixture. A peptide mixture containing a plurality of peptides is received. One or more peptides are separated from the peptide mixture over a period of time. One or more of the peptides separated at a particular time...

20060141632 - New methods and kits for sequencing polypeptides: The present disclosure provides methods and kits which are useful for sequencing polypeptides. The methods involve derivatization of the N-terminus of the polypeptide or peptides thereof. The methods also involve derivatization of the epsilon amino group of the side-chain of the lysine containing polypeptide or peptides thereof. Mass spectral analysis...

20060141633 - Method and system for characterization and mapping of tissue lesions: The present invention provides a method and an apparatus for the in vivo, non-invasive, early detection of alterations and mapping of the grade of these alterations, caused in the biochemical and/or in the functional characteristics of epithelial tissues during the development of tissue atypias, dysplasias, neoplasias and cancers. The method...

20060141634 - Determination of carbon nanotube concentration in a solution by fluorescence measurement: According to some embodiments, a method, a system, and an apparatus to determine a concentration of carbon nanotubes in a solution. In some embodiments, the method includes determining a photoluminescence intensity of a solution, mixing a sample of carbon nanotubes of an unknown concentration with the solution, determining a photoluminescence...

20060141635 - Method and apparatus for preprocessing sample according to form by hydride introduction method: A sample preprocessing method converts a substance to be measured in a sample solution into a volatile hydride and introduces the substance into an analytical device. The method includes the following steps (A) to (D) to be performed inside a reaction apparatus connected as a series of processes: (A) a...

20060141636 - Apparatus and method to elute microorganisms from a filter: There is provided apparatuses and methods for eluting microorganisms from filter media. The apparatus includes a housing for receiving filer media suspected of containing microorganisms and means for exposing the filter media to a pressurized buffer solution. By passing the buffer solution through the filter media under pressure, microorganisms trapped...

20060141637 - Multi-phase fluid sampling method and apparatus: The invention provides a method for producing a homogenous sample of a pressurized fluid stream flowing in a pipeline, the fluid stream consisting of a majority component of hydrocarbon gas, the remainder consisting of one or more hydrocarbon liquids and water in the form of vapor, aerosols, droplets and/or liquid...

20060141638 - Equine relaxin as a measure of treatment efficacy: A method for predicting treatment efficacy in pregnant mares affected by a disease or condition that alters placental function and results in a problematic pregnancy or delivery in the mare that is related to measurement of plasma relaxin levels is provided....

20060141639 - Positive detection lateral-flow apparatus and method for small and large analytes: Methods and devices for the detection and/or quantification of an analyte in a sample are provided. These are positive detection methods and devices, in that the more analyte is present in the sample, the stronger the signal that is provided. Devices of the invention include a mobilization zone including a...

20060134792 - Microarray comprising probes for drug-resistant hepatitis b virus detection, quality control and negative control, and method for detecting drug-resistant hepatitis b virus using the same: Provided are a microarray manufactured using a mixture of target probes for drug-resistant HBV detection, quality control probes for controlling quality in probe hybridization and fabrication of microarrays, and negative control probes for determining the presence and ratio of more than one type, i.e., a wild type and a mutant...

20060134793 - Method and apparatus for automated pre-treatment and processing of biological samples: The present invention concerns a method and apparatus for automatic staining or other processing of a biological sample on a slide, perhaps robotically, by applying predetermined amounts of reagents in a predetermined sequence according to a processing protocol, the processing including pre-treatment steps, under the control of an adaptive processing...

20060134794 - Method of detecting the presence and/or progression of cancer: Silver (II) Oxide preferentially reacts with tNOX a cancer-specific ECTO-NOX protein of the surface of cancer cells. The combination of the cancer specificity of tNOX and the interaction of silver II oxide specified herein with tNOX offer new and novel therapeutic and diagnostic opportunities including but not restricted to coupling...

20060134795 - Method of analyzing low levels of peroxyacetic acid in water: Methods of analyzing low levels of peroxyacetic acid (PAA) in water are described. These methods employ buffering the PAA-containing water and the use of a N,N-diethyl-p-phenylenediamine (DPD) indicator system in the presence of iodide ion. The intensity of the pink coloration that develops is quantitated by colorimetric or titrimetric methods...

20060134796 - Colorimetric sensors constructed of diacetylene materials: Colorimetric sensors for detection of an analyte are disclosed. Methods of using the colorimetric sensor and a kit for the colorimetric detection of an analyte are also disclosed....

20060134797 - Method and apparatus for desorption and ionization of analytes: This invention relates generally to methods and apparatus for desorption and ionization of analytes for the purpose of subsequent scientific analysis by such methods, for example, as mass spectrometry or biosensors. More specifically, this invention relates to the field of mass spectrometry, especially to the type of matrix-assisted laser desorption/ionization,...

20060134800 - Method and device for laminar flow on a sensing surface: Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell. The methods employ laminar flow techniques to position a fluid flow over one or more discrete sensing areas on the sensing surface of the flow cell. Such methods permit selective sensitization of...

20060134798 - Organic, metallorganic and biological material obtained from rock: The present invention concern s methods for obtaining from samples of rock of different natures, specifically chondrites, organic, metallorganic material or material of biological origin, and the materials themselves so obtained. In addition, the invention concerns their use in instrumentations exploiting their physical and physico-chemical properties, and fluorimetric methods to...

20060134799 - Thermally controlled fluidic self-assembly: Methods and apparatuses are provided for assembling a structure on a support having a pattern of binding sites. In accordance with the method, a first fluid is provided on the surface of the support with the first fluid being of a type that that increases viscosity when cooled, the first...

20060134801 - Methods and compositions involving mda-7: The present invention relates to compositions and methods involving MDA-7. More specifically, the present invention is directed to diagnostic, prognostic, and therapeutic treatment compositions and methods for treatment of cancer and other angiogenesis-related disorders (anti-angiogenesis therapy). The present invention is also directed to methods of purification of MDA-7....

20060134804 - Devices and methods for analyte assays with built-in result reporting using recognizable symbols: The present invention provides devices, methods and kits for detecting the presence of an analyte in a liquid sample. The invention provides devices having a positive control area covered with an opaque, movable material, such as an ink, dye, or other material, that is moved on the device by the...

20060134803 - Immunoassay devices and use thereof: An immunoassay device has a housing defining a first opening for receiving a solution and a second opening through which a liquid sample is deposited, a strip of sorbent material having a test site with immobilized antigen or antibody for the ligand to be tested, and a filter for filtering...

20060134805 - Purification of immunoglobulins: The present invention relates to a separation matrix comprised of porous particles to which antibody-binding protein ligands have been immobilised, wherein the ligand density is in the range of 5.0-10 mg/ml; the gel phase distribution coefficient of the particles expressed as Kav for a dextran of size 110 kDa is...

20060134802 - Solid-phase immunochromatographic methods: The invention concerns solid-phase immunochromatographic methods for detecting an analyte in a liquid sample. In the inventive methods, a binding reagent conjugated with a particulate marker is extemporaneously added in liquid form....

20060134806 - Method of separating unattached raman-active tag from bioassay or other reaction mixture: A method of separating a Raman-active tag unattached to a target from a Raman-active complex is disclosed. The Raman-active complex includes a Raman-active tag attached to a target. The method includes providing a mixture including at least one Raman-active tag unattached to a target and at least one Raman-active complex;...

20060128022 - Process control method and process control system: A process control system has a data storage section which saves process data output from a sensor placed in a plant which performs a continuous process, a trace information processing section which acquires process information of a product moving in the plant and being discrete in a predetermined unit from...

20060128024 - Apparatus and method for immunological labeling for thin tissue sections: An apparatus and a method for immunological labeling of thin tissue sections are disclosed. The treatment fluid is applied in the form of liquid droplets onto at least one slide, the arrangement of liquid droplets corresponding to the arrangement of the thin tissue sections on the carrier plate. Each slide...

20060128023 - Networked rf tag for tracking freight: The invention disclosed provides a method, system, and associated tag for detection and tracking of inanimate and animate objects. The novel method broadly comprises the steps of: a) attaching a low radio frequency detection tag to each of the objects, each tag comprising a tag antenna operable at a low...

20060128025 - Method for monitoring degradation of lubricating oils: wherein R1 and R2 independently are hydrogen, hydroxy, OR11, amino or NR11R12; R3 and R5 independently are alkyl, aryl, aralkyl, heteroalkyl or heterocyclic; R4 and R6 independently are hydrogen or alkyl; R7, R8, R9 and R10 independently are cyano, nitro, amide, carboxyl, ester, alkyl or hydrogen; R11 is alkyl, aryl,...

20060128026 - Biochemical analysis kit and method for exposing stimulable phosphor sheet: A biochemical analysis kit includes a biochemical analysis unit including a substrate capable of attenuating radiation energy and light energy and formed with a plurality of absorptive regions to be spaced apart from each other, and a stimulable phosphor sheet including a support formed with a plurality of stimulable phosphor...

20060128028 - Analysis of semiconductor copper plating bath chemistry using in process mass spectrometry: An in-process mass spectrometry (IPMS) system is disclosed that uses an internal standard to determine the concentration of an analyte in a sample. The internal standard has a different molecular composition than the analyte but is sufficiently similar chemically and physically to the analyte such that it behaves substantially the...

20060128027 - Method for interpreting tandem mass spectrometry data for clinical diagnosis: A method for interpreting data that is produced after a group of amino acids and acylcarnitines are derivatized from blood spots taken from newborn babies and scanned by a tandem mass spectrometer. Concentration levels of each metabolite, which are directly proportional to the butyl ester fragment after derivatization, are compared...

20060128029 - Method for the determination of an analyte in a liquid: A method is provided to determine the presence of an analyte in a sample. The method provides an element with a sample application zone, a detection zone, a zone containing immobilized analyte or analyte analogue, a conjugate that has a first bioaffine binding partner capable of a specific binding reaction...

20060128031 - Addressable recovery of bound analytes from an evanescent wave sensor: The invention provides an evanescent wave sensor containing a cleavably bound capture agent. Upon exposure of the sensor to a suitable stimulus the capture agent and any analyte bound thereto are released from the sensor. The released analyte may be transferred into a mass spectrometer apparatus and investigated therein....

20060128030 - Bioassay substrate and bioassay device and method: A bioassay substrate (1) takes a flat-plate shape in which the principal surface similar to that of optical disc such as CD, etc. is circular. At the center of the substrate (1), there is formed a center hole (2) into which a chucking mechanism for rotation and holding is inserted....

20060128032 - Biosensor: It is an object of the present invention to provide a detection surface used for biosensors, in which non-specific adsorption is suppressed and the generation of pinholes is also suppressed. The present invention provides a biosensor, which comprises a substrate coated with a hydrophobic polymer having an alkyl group substituted...

20060128033 - Fluorogenic dyes: Fluorogenic or chromogenic dyes are useful as reporter molecules for detecting cell entry by a specific molecule....

20060128034 - Diagnostic test using gated measurement of fluorescence from quantum dots: A rapid diagnostic test system or process uses a gated measurement of the fluorescent light from quantum dots after shutting off an illuminating light source. A delay between shutting off the illumination and measuring allows background fluorescence from substances other than the quantum dots to drop significantly when compared to...

20060128035 - Sensor and method for measuring the areal density of magnetic nanoparticles on a micro-array: A magnetoresistive sensor device for measuring an areal density of magnetic nanoparticles on a micro-array, the magnetic nanoparticles (15) being directly or indirectly coupled to the target sample (11), is described. The magnetoresistive sensor device comprises a substrate (3) having attached thereto binding sites (9) able to selectively bind target...

20060115902 - Cell lysis method using free radical: Provided is a method of lysing a cell or a virus using a free radical. The method includes: applying an electric field to a mixture of a metal ion, a peroxide, and a cell or virus solution to increase the free radical generation, thereby lysing a cell or a virus....

20060115903 - Relevance of achieved levels of markers of systemic inflammation following treatment: The invention involves, inter alia, the use of markers of systemic inflammation to determine whether or not an individual undergoing treatment with a cardiovascular agent to reduce the risk of a future cardiovascular event will benefit from continued treatment with the cardiovascular agent. Further, this invention describes the use of...

20060115904 - Partial modulation via pulsed flow modulator for comprehensive two-dimensional liquid or gas chromatography with multiple modulation periods: This invention is a method and device for use with multi-dimensional chromatography that utilizes partial modulation with multiple secondary retention times. An analyte-bearing sample is subjected to a first dimension of chromatography. Thereafter the separated analyte-bearing sample is diluted with a modulated second carrier such at the analyte-bearing sample is...

20060115905 - Microscale diffusion immunoassay in hydrogels: A diffusion immunoassay (DIA) for determining the presence and concentration of analyte particles by detecting the diffusion front. A hydrogel containing immobilized binding particles is placed in contact with a carrier fluid containing analyte particles, which analyte particles diffuse into the hydrogel and bind with the immobilized binding particles. A...

20060115907 - Immune complex-specific antibodies for increased sensitivity in immunoassay array tests: The invention concerns a method for determining antigen-specific antibodies of a particular immunoglobulin class in a sample by means of an immunoassay in an array format in which various binding partners Bnx are bound on different discrete areas on a support where Bnx in each case contain the various antigens...

20060115906 - Sensor surface comprising an improved signal-noise ratio: The present invention concerns a sensor surface with an improved signal/noise ratio that is based on a blocking reagent covalently immobilized on the sensor surface, as well as apparatuses comprising such surfaces and methods for the use of same....

20060115908 - Multiplexed analyses of contaminant-laden gas in a particle impact collector: Air or gas is drawn into a particle impact collector where the air or gas is forced through non-linear passages inside the collector in such a manner that particles or droplets entrained in the air or gas, or contaminant vapors in the air or gas, are retained in and concentrated...