Chemistry: analytical and immunological testing inventions 01/06

20060019398 - Method and system for molecular array scanner calibration: A method and system for calibrating molecular arrays to a reference molecular array, and for subsequently calibrating the molecular arrays to maintain a constant signal-intensity-to-label-concentration ratio. In the first step of the two-step calibration method, a reference array coated with the fluorophore or chromophore used to label probe molecules is...

20060019399 - Devices and methods for correlated analysis of multiple protein or peptide samples: Disclosed is a system for performing multiple analyses of protein and/or peptide samples and correlating the results of the analyses. The system comprises a sample inlet, a splitter means, at least two sample delivery capillaries, at least two sample deposition tools, and at least two sample collectors, wherein said splitter...

20060019400 - Method for the determination of glucuronides in physiological samples: The present invention provides methods and kits for the detection of glucuronide metabolites of various drugs, alcohols and other compounds using a combination of High Performance Liquid Chromatography coupled with Pulsed Electrochemical Detection. Detection of a drug and its glucuronide metabolite(s) has applications in interpretive forensic and clinical toxicology. The...

20060019401 - Monitoring the stability of vinylog compounds: The process is used to monitor the stability of compositions and reaction mixtures which contain vinylog compounds, more especially (meth)acrylic acid and/or (meth)acrylates. The content of dissolved oxygen in the composition or in the reaction mixture is determined and compared with predetermined reference values. Incipient or threatening polymerization is detected...

20060019402 - Method of warning of poisoning in poison resistant combustible gas sensors: A poison resistant combustible gas sensing element, a method for its production and a method for determining poisoning of the element. The element includes an electric heating element, an inner layer coated on the electric heating element and containing a precious metal catalyst supported on a porous oxide, the precious...

20060019403 - Method for determining the oxygen demand of an aqueous solution for a purification process: Method of determining the oxygen demand, TOD or COD, of an aqueous solution, in particular of waste water, for a clarification process, wherein a sample of the aqueous solution is decomposed by combustion, such that the combustion is carried out without the presence of a catalyst, at a temperature above...

20060019404 - Quantitative assay with extended dynamic range: An efficient design for an expanded dynamic range in a lateral flow one step assay for the detection of an analyte in a biological sample is disclosed. The device comprises a multiple strip design, each constructed of four zones; a sample receiving zone, a sample treatment zone, a labeling zone,...

20060019405 - Cat lavator comprising an urine test: The present invention relates to a cat lavatory including at least one absorbent material comprising an insert of non-woven material, at least one indicator strip for determining a cat's urine levels, which is arranged on and/or in the absorbent material; and a method of determining a cat's urine levels using...

20060019407 - Immunoassay assembly and methods of use: The present invention relates to an improved system for efficiently and accurately performing immunoassays, such as ELISAs. The invention provides an immunoassay assembly which includes a flow-through unit and an aspiration pump. The immunoassay flow-through unit includes an outer seal; at least one bed support; an inner seal; and a...

20060019406 - Lateral flow device for the detection of large pathogens: There is provided a lateral flow assay device for detecting the presence or quantity of an analyte residing in a test sample where the lateral flow assay device has a porous membrane in communication with a conjugate pad and a wicking pad. The porous membrane has a detection zone where...

20060019408 - Optical biosensors and methods of use thereof: A fundamental biosensor for detection of biological or environmental analytes is provided. The biosensor comprises a selectivity component for recognition of a target molecule and a reporter molecule that is sensitive to changes in the microenvironment. Methods of using the biosensor are also provided, including in vivo and in vitro...

20060019409 - Spectroscopic methods for component particle analysis: The invention relates to methods of assessing one or more geometric properties of a particle of a substance using an infrared spectroscopic property of the substance. The method is useful, for example, for assessing particle sizes and size distributions in mixtures containing both particles of the substance and other materials....

20060019410 - Apparatus, kits and methods for evaluating binding interactions, for detecting and quantifying binding molecules, and for sample preparation: The present invention provides apparatus, kits and methods for evaluating binding between one or more binding molecules (e.g., a protein) and one or more ligands. The invention also provides apparatus, kits and methods for detecting and/or quantifying a binding molecule, for example, a protein. Also provided are apparatus, kits and...

20060014292 - Process and system for controlling a process gas stream: In a process and system for recovering sulfur from a process gas stream initially comprising a hydrogen sulfide containing gas and an oxygen containing gas, a control process and system respectively are provided. The sulfur recovery process includes a thermal step having a beginning followed by a catalytic step having...

20060014293 - Lock mass ions for use with derivatized peptides for de novo sequencing using tandem mass spectrometry: Multiple derivatization by chemical reactions of analytes for mass spectrometry is disclosed. The derivatizations enhance the use of MS techniques for analyzing protein samples, particularly when the sequence of a polypeptide is determined by tandem MS/MS. Accurate mass analysis techniques are described for use in sequencing polypeptides, together with the...

20060014294 - Serum marker for measuring liver fibrosis: The invention provides methods and kits to detect liver fibrosis or a change in the gradation of liver fibrosis in mammals. The diagnostic marker is based on the profiling and identification of diagnostic carbohydrates present in a body fluid such as blood serum....

20060014295 - Arrangement and method for the analysis of body fluids: The invention relates to an arrangement and a method for the analysis of body fluids (21), whereby an image recording device (30) is arranged in a low-reflection, preferably zero-reflection chamber (16), provided with an illumination device (45) and connected to an electronic image analyzer. The image recording device (30) is...

20060014296 - Method for refinery foulant deposit characterization: The present invention is a method to identify a refinery solid foulant of unknown composition including the following steps: obtaining a solid foulant sample, removing trapped feed from the sample with a solvent to obtain an insoluble sample, scanning the insoluble sample with a scanning electron microscope and energy dispersive...

20060014297 - Clinical method for the genetic screening of newborns using tandem mass spectrometry: A method for screening newborns using electrospray tandem mass spectrometry. The method improves the current protocols that use tandem mass spectrometry by assuring accurate and consistent results at the clinical level through enhanced quality controls and quality assurance protocols as applied to the scan profiling and sample preparation of blood...

20060014298 - Method and kitset for sampling and storage of biological samplies: The invention relates to a method and kitset for rapid collecting and storing of a plurality of biological samples for later identification of the individual sources of the samples. The preferred types of samples described are sources of DNA such as blood. The invention is particularly useful in the tracing...

20060014299 - Method for analyzing blood for cholesterol components: A method for detecting and quantifying lipoprotein subgroup concentration in a blood serum sample in a single spin cycle using a fluorescent dye and a self generating continuous gradient followed fluorescent dye detection and quantitation....

20060014301 - Antibody-based system for detection of differential protein expression patterns: The present invention is a kit and method for identifying the presence or absence of a protein expression profile that is known to be associated with a particular disease or an altered biological state. The method is based on the combination of a known protein expression pattern biomarker with the...

20060014302 - Point of care diagnostic systems: Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate result is desired. The...

20060014300 - Sensor for detection and identification of biological particles: The illustrative embodiment of the present invention is a system and a method for the detection and limited identification of biological agents. The system is small, light weight, requires little power to operate and uses few consumables. The system can be configured for use in either stationary or mobile applications....

20060008912 - Temporary visual indicators for paint and other compositions: The present invention concerns novel methods and compositions useful for providing a temporary visual indication of the location, concentration, and/or time period of treatment of an applied material. The subject invention provides compositions and methods that use a temporary visual indicator. In certain embodiments, the temporary visual indicator is a...

20060008913 - Microfluidic separator: The present invention provides methods and apparatus for separating and/or analyzing fluids of interest. According to principles of the present invention, fluid analysis is accomplished with microfluidic devices and may be reported in real-time or near real-time in a subterranean environment. In addition or alternative to oilfield applications, the principles...

20060008914 - Test device for determining the concentration of ldl-cholesterol in a sample: The present invention provides a test device for determining the concentration of LDL cholesterol in a sample, comprising a solid surface with at least one reaction area, said at least one reaction area being provided with an Non-LDL inhibitor and a system for determining the concentration of cholesterol....

20060008916 - Method for measuring strontium isotope ratios using mass spectrometer: The invention put forward an improved method for isotope dilution analysis of strontium using mass spectrometer. The sample of strontium is measured by a multi-collector mass spectrometer which equipped with no less than five collectors. The isotopes of strontium are statically collected by the collectors: ion beams with different mass...

20060008915 - Reagent for determination of calcium and determination method: A method for determination of calcium in a sample derived from a living body, by the reaction of calcium in the sample with Chlorophosphonazo-III or a compound analogous thereto in the presence of vanadate ions, followed by determination of calcium in the sample on the basis of an optical change...

20060008917 - Diagnostic methods for determining susceptibility to convulsive conditions: The present invention exploits the discovery that amounts of uracil and thymine metabolites, especially β-aminoisobutyric acid, in various bodily fluids, especially urine, are correlated with the occurrence of epilepsy when compared to matched control subjects. Analytical and diagnostic protocols, including a novel high performance liquid chromatography system, for use in...

20060008918 - Detection of disease by analysis of emissions: A method of determining the cause of disease is described, which method uses the detection of “signature” or “fingerprint” volatile compounds in an emission, especially flatus, from a patient....

20060008919 - Method and apparatus for detecting gas/radiation that employs color change detection mechanism: Method and apparatus for detecting the presence of an analyte (e.g., gas/radiation) that utilizes color change detection mechanisms. The apparatus has an indicator that changes color in the presence of the analyte. For example, in the absence of the analyte, the indicator reflects a first color. In the presence of...

20060008920 - Combination assay for alcohol and drugs of abuse: A test apparatus that allows testing for the presence of both drugs of abuse and alcohol within a single device. In general, the apparatus of the present invention includes a lateral flow immunoassay screening for various drugs of abuse and a reactive pad including an enzyme as a test for...

20060008921 - Immunochromatographic methods for detecting an analyte in a sample which employ semiconductor nanocrystals as detectable labels: Immunochromatographic test strip assays which employ semiconductor nanocrystals as detectable labels are disclosed, as are methods for detecting and quantifying one or more analytes of interest in a test sample using those assays. The test strips of the present invention permit detection and quantitation of one or more analytes of...

20060008922 - Clinical method for the genetic screening of newborns using tandem mass spectrometry and internal standards therefor: A method for screening newborns using electrospray tandem mass spectrometry. The method improves the current protocols that use tandem mass spectrometry by assuring accurate and consistent results at the clinical level through enhanced quality controls and quality assurance protocols as applied to the scan profiling and sample preparation of blood...

20060008923 - Point of care diagnostic systems: Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate result is desired. The...

20060008924 - Modulated physical and chemical sensors: The present invention relates to modulated (e.g., magnetically modulated) chemical sensors. In particular, the present invention relates to particles comprising fluorescent indicator dyes and methods of using such particles. Magnetic fields and/or Brownian motion modulate an optical property of the particle to distinguish it from background signals. The present invention...

20060003455 - Method for analyzing impurity: This method for analyzing impurity includes: a step of immersing each of sets of two evaluation silicon wafers into a washing solution, thereby contaminating the evaluation silicon wafers to be in a same state of contamination; a step of dissolving each of a surface layer portion of either one of...

20060003456 - System, method and apparatus for lost foam casting analysis: Disclosed are a method, system and apparatus for analyzing foam decomposition in contact mode during mold filling in lost foam casting, the foam decomposition having a foam material vapor fraction and the mold filling having a mold filling speed. The method includes providing a plurality of parameter values for casting...

20060003457 - Redox polymer nanoparticles: The invention provides nanoparticles comprising one or more redox-active species, methods of making such nanoparticles, and methods for using such nanoparticles, for example, as diagnostic agents for the detection of various analytes....

20060003459 - Determining enantiomeric excess using indicator-displacement assays: The invention includes an enantioselective indicator-displacement assay useful to determine enantiomeric excess (ee) enantiomeric samples calorimetrically. Determination may be by inspection of color with the naked eye, spectrographic measurement, or mathematical calculation. Concentration may also be determined. The assay may involve two independent absorption measurements. On suitable group of enantiomeric...

20060003460 - Method for comparing proteomes: The present invention relates to an improved method for comparing two or more samples containing proteins. This invention consists in first correlating and selecting the huge amount of data generated by mass spectrometry (PMF and MS/MS) before any kind of protein identification process, and then only identifying the proteins that...

20060003458 - Study of polymer molecules and conformations with a nanopore: The invention features methods for evaluating the conformation of a polymer, for example, for determining the conformational distribution of a plurality of polymers and to detect binding or denaturation events. The methods employ a nanopore which the polymer, e.g., a nucleic acid, traverses. As the polymer traverses the nanopore, measurements...

20060003461 - Method for determining the concentration of hydrogen peroxide in a process stream and a spectrophotometric system for the same: The present invention is directed to a method for determining the concentration of hydrogen peroxide in a chemical process stream which may include interfering components. Still further, this invention is directed to a method and apparatus for the on-line, automated determination and control of hydrogen peroxide in a process stream....

20060003462 - Dual-slot biological test meter test procedure: A dual-slot biological test meter test procedure includes the steps of 1) inserting a code card into the first test slot of a dual-slot biological test meter to input predetermined parameters and then inserting a test strip into the second test slot to initiate the dual-slot biological test meter, 2)...

20060003463 - Methods for assaying or isolating constituents of samples: Methods for assaying or isolating constituents of samples include applying a sample to a capillary column, which includes a matrix that includes the same material as a nonporous substrate within which the capillary column is formed, as well as drawing the sample through at least a portion of a length...

20060003465 - Luminescence characterization of quantum dots conjugated with biomarkers for early cancer detection: Luminescent semiconductor quantum dots (QDs) conjugated with biomolecules to serve as sensitive probes for early detection of the cancer cells, specifically for ovarian cancer and lung cancer, which represents the most lethal malignancies. The luminescence characterization of the bin-conjugated QDs with cancer specific antigens using linkage molecules. Photo-enhancement is measured...

20060003464 - Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes: A semiconductor nanocrystal compound is described capable of linking to an affinity molecule. The compound comprises (1) a semiconductor nanocrystal capable of emitting electromagnetic radiation and/or absorbing energy, and/or scattering or diffracting electromagnetic radiation—when excited by an electromagnetic radiation source or a particle beam; and (2) at least one linking...

20060003466 - Nanometer-sized up-converting phosphor fluoride particles and process of preparation: Nanometer-scaled up-converting fluoride phosphor particles and processes of making them are disclosed. In the process, an aqueous solution consisting of soluble salts of rare-earth metal ions at a molar ratio of (yttrium, lanthanum or gadolinium): ytterbium:(erbium, holmium, terbium or thulium)=(70-90):(0-29):(0.001-15) is mixed a rare-earth metal chelator and a soluble fluoride...