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08/04/05 - USPTO Class 514 |  95 views | #20050171103 | Prev - Next | About this Page  514 rss/xml feed  monitor keywords

Benzamide derivatives useful as histone deacetylase inhibitors

USPTO Application #: 20050171103
Title: Benzamide derivatives useful as histone deacetylase inhibitors
Abstract: The invention concerns a compound of the formula (I) wherein Ring A is heterocyclyl; m is 0-4 and each R1 is a group such as hydroxy, halo, trifluoromethyl and cyano; R2 is, halo and n is 0-2; and each R4 is a group such as hydroxy, halo, trifluoromethyl and cyano; p is 0-4; and R3 is amino or hydroxy; or pharmaceutically-acceptable salts or in-vivo-hydrolysable ester or amide thereof processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical condions mediated by histone deacetylase.
(end of abstract)
Agent: Astrazeneca R&d Boston - Waltham, MA, US
Inventors: Elaine Sophie Elizabeth Stokes, Craig Anthony Roberts, Michael James Waring
USPTO Applicaton #: 20050171103 - Class: 514237500 (USPTO)

Related Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Designated Organic Active Ingredient Containing (doai), Heterocyclic Carbon Compounds Containing A Hetero Ring Having Chalcogen (i.e., O,s,se Or Te) Or Nitrogen As The Only Ring Hetero Atoms Doai, Hetero Ring Is Six-membered And Includes At Least Nitrogen And Oxygen As Ring Hetero Atoms (e.g., Monocyclic 1,2- And 1,3-oxazines, Etc.), Morpholines (i.e., Fully Hydrogenated 1,4- Oxazines), Having -c(=x)-, Wherein X Is Chalcogen, Bonded Directly To The Morpholine Ring

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