| Agents for promoting fattening of animals and method of promoting fattening -> Monitor Keywords |
|
|
  Agents for promoting fattening of animals and method of promoting fatteningUSPTO Application #: 20060128795Title: Agents for promoting fattening of animals and method of promoting fattening Abstract: Agents for promoting fattening of animals which contain as the active ingredient(s) at least one member selected from among acids originating in hexoses, non-toxic salts thereof and intramolecular esterification products thereof; and a method of promoting fattening by using these agents. (end of abstract) Agent: Oblon, Spivak, Mcclelland, Maier & Neustadt, P.C. - Alexandria, VA, US Inventors: Hironari Koyama, Masaaki Okada USPTO Applicaton #: 20060128795 - Class: 514460000 (USPTO) Related Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Designated Organic Active Ingredient Containing (doai), Heterocyclic Carbon Compounds Containing A Hetero Ring Having Chalcogen (i.e., O,s,se Or Te) Or Nitrogen As The Only Ring Hetero Atoms Doai, Oxygen Containing Hetero Ring, The Hetero Ring Is Six-membered, Chalcogen Bonded Directly To Ring Carbon Of The Hetero Ring The Patent Description & Claims data below is from USPTO Patent Application 20060128795. Brief Patent Description - Full Patent Description - Patent Application Claims
TECHNICAL FIELD [0001] The present invention relates to an agent for promoting the fattening of animals and to a method for promoting the fattening of animals. More precisely, the invention relates to an agent for promoting the fattening of animals, which contains, as an active ingredient, at least one of hexose-derived acids such as typically gluconic acid, and their non-toxic salts and intramolecular ester compounds, and to a method of promoting the fattening of animals by use thereof. BACKGROUND ART [0002] For promoting the growth of animals such as livestock, antibiotics such as tetracycline and avoparcin have heretofore been used by being added to feed as fattening promoters. However, these antibiotics often induce resistant bacteria through mutation in the body of animals. In addition, they may remain in the body of animals, and the human beings who have eaten the meat of the animals shall inevitably take the antibiotics. As a result, the potency of antibiotics serving as medicines will be thereby lowered. [0003] Recently, therefore, substances except antibiotics have been investigated for fattening promoters for animals. For example, fumaric acid is used as a fattening promoter. [0004] On the other hand, gluconic acid which is one typical example of hexose-derived acids has heretofore been widely used. For example, its intramolecular ester compound, glucono delta lactone is known as a coagulant for tofu (soybean curd); and calcium gluconate is known as a calcium supplement. In addition, sodium gluconate and potassium gluconate have been officially approved as food additives recently and are used in various edibles (International Patent No. WO94/09650). DISCLOSURE OF THE INVENTION [0005] The inventors of the present invention have tried administering gluconic acid and its derivatives, which are highly safe to living bodies, to animals and analyzing their activity to the living bodies. Having specifically examined their effect in the animal intestines, the inventors have found unexpectedly that they promote the growth of specific enterobacteria in the animals and that the thus-growing enterobacteria significantly increase the production of short-chain fatty acids which are effective for the growth of the living bodies. In addition, the inventors have further found that the production of substances that will be harmful to living bodies is reduced or eliminated. [0006] That is, if hexose-derived acids and their non-toxic salts and intramolecular ester compounds (hereinafter the term "hexose-derived acids" generally includes all these compounds) are administered to animals, Megasphaera and Mitsuokella, precisely Megasphaera elsdenii and Mitsuokella multiacidus, among enterobacteria in the animals are specifically proliferated. [0007] On the other hand, as compared with the absence of the hexose derived acids, the production of acetic acid, propionic acid and butyric acid which are short-chain fatty acids is promoted about 2 times, about 4 times and about 8 times more, respectively. At the same time, the production of lactic acid, succinic acid, ammonia and hydrogen sulfide which are reported to have some negative influences such as diarrhea, digestive tract ulcers, lumen acidosis, etc. on living bodies is reduced or eliminated. [0008] Therefore, if the hexose-derived acids are given to animals, the production of short-chain fatty acids is promoted in the living bodies of the animals, and, as a result, the feed efficiency is improved remarkably and the fattening of the animals is thereby accelerated. BRIEF DESCRIPTION OF THE DRAWINGS [0009] FIG. 1 is a graph showing the results of Test Example 1. [0010] FIG. 2 is a graph showing the results of Test Example 4. BEST MODES OF CARRYING OUT THE INVENTION [0011] The hexose-derived acids in the invention may be any of D-forms, L-forms or their mixtures. For example, they include saccharic acids such as glucaric acid, mannaric acid, gularic acid, idalic acid, etc.; and aldonic acids such as gluconic acid, galactonic acid, mannoic acid, talonic acid, allonic acid, etc., of which gluconic acid is especially preferred. [0012] The non-toxic salts of these acids include, for example, salts thereof with alkali metals such as sodium or potassium, salts thereof with alkaline earth metals such as calcium or magnesium, and salts thereof with transition metals such as copper, iron or zinc, of which sodium gluconate and calcium gluconate are especially preferred. [0013] The intramolecular ester compounds of the acids are, for example, lactone compounds. For example, mentioned are intramolecular ester compounds of gluconic acid, such as glucono delta lactone, glucono gamma lactone, of which glucono delta lactone is especially preferred. [0014] These hexose-derived acids may be used alone or as an optional combination of two or more thereof. [0015] As the short-chain fatty acids, may be mentioned fatty acids having two to four carbon atoms such as acetic acid, propionic acid, butyric acid, isobutyric acid, valeric acid, isovaleric acid, caprylic acid, etc. Lactic acid and succinic acid which differ from these acids in their intracorporeal absorption mechanism and in their influences on living bodies are not included within the scope of the short-chain fatty acids in the present invention. [0016] The wording "improvement of feed efficiency" essentially means that even poorly-nutritious animal feed prepared from poor-quality cereals can attain almost the same level of fattening-promoting effect as that of highly-nutritious high-quality feed by addition of any of the hexose-derived acids thereto, but it also means that, when any of the hexose-derived acids is added to highly-nutritious feed, the feed attains a more elevated fattening-promoting effect. [0017] The hexose-derived acids may be used as they are, but may be combined with solid or liquid vehicles well known in the art such as lactose, sucrose, glucose, corn starch, gelatin, starch, water, glycerin, fatty oil, sorbitol and the like to be used as agents for promoting the fattening of animals, agents for promoting the growth of animal enterobacteria, and agents for inhibiting the production of intracorporeal harmful substances. [0018] These agents may be optionally mixed with ordinary additives such as antibacterial agents, antifungal agents, anthelminthics, antioxidants, dyes, flavorings, seasonings and enzymes, and may be prepared in the form of powders, dispersions, granules, liquid, tablets and the like by conventional methods. [0019] The agents may be administered to animals as they are, or may be added to feed or drinking water to be taken by animals. Preferably, they are blended to feed or drinking water for animals. Continue reading... Full patent description for Agents for promoting fattening of animals and method of promoting fattening Brief Patent Description - Full Patent Description - Patent Application Claims Click on the above for other options relating to this Agents for promoting fattening of animals and method of promoting fattening patent application. ###  How KEYWORD MONITOR works... a FREE service from FreshPatents1. Sign up (takes 30 seconds). 2. Fill in the keywords to be monitored. 3. Each week you receive an email with patent applications related to your keywords. Start now! - Receive info on patent apps like Agents for promoting fattening of animals and method of promoting fattening or other areas of interest. ### Previous Patent Application: Treatment of interstitial cystitis using (6ar,10ar)-delta8-tetrahydrocannabinol-11-oic acids Next Patent Application: Active substance combinations comprising insecticidal and acaricidal properties Industry Class: Drug, bio-affecting and body treating compositions ### FreshPatents.com Support Thank you for viewing the Agents for promoting fattening of animals and method of promoting fattening patent info. IP-related news and info Results in 1.59037 seconds Other interesting Feshpatents.com categories: Software: Finance , AI , Databases , Development , Document , Navigation , Error |
||
