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Sequestered antagonist formulations

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Sequestered antagonist formulations

Disclosed is an oral dosage form comprising (i) an opioid agonist in releasable form and (ii) a sequestered opioid antagonist which is substantially not released when the dosage form is administered intact, such that the ratio of the mean Cmax of the antagonist after single dose oral administration of the dosage form after tampering to the mean Cmax of antagonist after single dose oral administration of an intact dosage form is at least 1.5:1.

USPTO Applicaton #: #20140099376 - Class: 424490 (USPTO) -

Inventors: Christopher Breder, Benjamin Oshlack, Curtis Wright

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The Patent Description & Claims data below is from USPTO Patent Application 20140099376, Sequestered antagonist formulations.

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Drug, bio-affecting and body treating compositions
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