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Compounds useful for treating cancer / Centre National De La Recherche Scientifique




Title: Compounds useful for treating cancer.
Abstract: The present invention relates to compound (I) wherein: means a pyridazine, a pyrimidine or a pyrazine group, R independently represent a hydrogen atom, a halogen atom or a group chosen among a CN group, a hydroxyl group, a COOR1 group, a (C1-C3)fluoroalkyl group, a (C1-C3)fluoroalkoxy group, a NO2 group, a NR1R2 group, a (C1-C4)alkoxy group, a phenoxy group and a (C1-C3)alkyl group, said alkyl being optionally mono-substituted by a hydroxyl group, n is 1, 2 or 3, n is 1 or 2, R is a hydrogen atom, a halogen atom or a group chosen among a (C1-C3)alkyl group, a hydroxyl group, a COOR1 group, a NO2 group, a NR1R2 group, a morpholinyl or a morpholino group, a N-methylpiperazinyl group, a (C1-C3)fluoroalkyl group, a (C1-C4)alkoxy group and a CN group, Z is N or C, Y is N or C, X is N or C, W is N or C, T is N or C, U is N or C, for use as an agent for preventing, inhibiting or treating cancer. Some of said compounds are new and also form part of the invention. ...


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USPTO Applicaton #: #20120277230
Inventors: Pierre Roux, Florence Mahuteau, Romain Najman, Jamal Tazi, Gilles Gadea, Didier Scherrer, Carsten Brock, Nathalie Cahuzac


The Patent Description & Claims data below is from USPTO Patent Application 20120277230, Compounds useful for treating cancer.




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stats Patent Info
Application #
US 20120277230 A1
Publish Date
11/01/2012
Document #
13377745
File Date
06/14/2010
USPTO Class
5142352
Other USPTO Classes
546162, 514313, 546160, 544405, 51425505, 544356, 514249, 544331, 514272, 546159, 544128, 435375
International Class
/
Drawings
0


Pyrazine

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Centre National De La Recherche Scientifique


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Drug, Bio-affecting And Body Treating Compositions   Designated Organic Active Ingredient Containing (doai)   Heterocyclic Carbon Compounds Containing A Hetero Ring Having Chalcogen (i.e., O,s,se Or Te) Or Nitrogen As The Only Ring Hetero Atoms Doai   Hetero Ring Is Six-membered And Includes At Least Nitrogen And Oxygen As Ring Hetero Atoms (e.g., Monocyclic 1,2- And 1,3-oxazines, Etc.)   Morpholines (i.e., Fully Hydrogenated 1,4- Oxazines)   Additional Hetero Ring Attached Directly Or Indirectly To The Morpholine Ring By Nonionic Bonding   Polycyclo Ring System Having The Additional Hetero Ring As One Of The Cyclos  

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20121101|20120277230|compounds useful for treating cancer|The present invention relates to compound (I) wherein: means a pyridazine, a pyrimidine or a pyrazine group, R independently represent a hydrogen atom, a halogen atom or a group chosen among a CN group, a hydroxyl group, a COOR1 group, a (C1-C3)fluoroalkyl group, a (C1-C3)fluoroalkoxy group, a NO2 group, a |Centre-National-De-La-Recherche-Scientifique
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