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Organic compounds

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Organic compounds

The present invention relates to a novel selection system for use in a eukaryotic cell culture process and for expression of a recombinant product of interest. The selection system is based on the introduction of an exogenous functional membrane-bound folate receptor gene together with the polynucleotide or gene encoding the product of interest into a eukaryotic cell and can be widely utilized with eukaryotic cells for which cellular viability is dependent upon folic acid uptake.

Browse recent Novartis Ag patents - Basel, CH
Inventors: Yehuda G. Assaraf, Thomas Jostock, Hans-Peter Knopf
USPTO Applicaton #: #20120276579 - Class: 435 34 (USPTO) - 11/01/12 - Class 435 

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The Patent Description & Claims data below is from USPTO Patent Application 20120276579, Organic compounds.

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Microorganism concentration process and concentration agent for use therein
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