Follow us on Twitter
twitter icon@FreshPatents

Browse patents:
Next
Prev

Somatic cells for use in cell therapy / Core Dynamics Limited




Title: Somatic cells for use in cell therapy.
Abstract: The present invention generally concerns cell therapy and products for use in such therapy. Particularly, the invention provides a preserved cell preparation essentially free of one or more members of a group of cryoprotecting agents consisting of polyalcohols, DMSO and cryoprotecting proteins, the preserved cell preparation comprising somatic cells and at least one polyphenol, wherein upon reconstitution of cells in the cell preparation, at least a portion of said stem cells are viable, said portion being sufficient for use of the cell preparation in stem cell therapy. The invention also provides cells reconstituted from preserved somatic cells, and the use of the reconstituted cells in cell therapy. A preferred cell preparation in accordance with the invention comprises stem cells, preferably human stem cells. ...


Browse recent Core Dynamics Limited patents


USPTO Applicaton #: #20100105133
Inventors: Tamir Kanias, Yehudit Natan


The Patent Description & Claims data below is from USPTO Patent Application 20100105133, Somatic cells for use in cell therapy.

FIELD OF THE INVENTION

- Top of Page


This invention relates to cell therapy and in particular to products and methods for use in somatic cells therapy such as stem cell therapy.

LIST OF REFERENCES

The following references are considered to be pertinent for the purpose of understanding the background of the present invention: 1. WO 03/020874, Improved Method for Freezing Viable Cells; 2. U.S. Pat. No. 5,827,741, Cryopreservation of Human Adult and Fetal Pancreatic Cells and Human Platelets; 3. U.S. Pat. No. 6,723,497, Therapeutic Platelets and Methods; 4. Chen et al. 2001, Beneficial effect of intracellular trehalose on the membrane integrity of dried mammalian cells. Cryobiology 43(2):168-81. 5. Crowe et al. 2003, Stabilization of membranes in human platelets freeze-dried with trehalose. Chem. Phys. Lipids. 122(1-2):41-52. 6. Fujiki et al. 1999, Mechanistic Findings of Green Tea as Cancer Preventive for Humans. Proc. Soc. Exp. Biol. Med. 220(4) 225-228; 7. Kumazawa et al. 2004, Direct evidence of interaction of a green tea polyphenol, epigallocatechin gallate, with lipid bilayers by solid-state Nuclear Magnetic Resonance. Biosci Biotechnol Biochem. 68, 1743-7. 8. Suganuma et al. 1999, Green Tea and Chemprevention Mutation Research 428, 339-344. 9. Sherry Chow et al. 2001, Cancer Epidemiology, Biomarkers & Prevention 10, 53-58 10. FDA, CBER, 1998, Guidance for human somatic cell therapy and gene therapy; 11. US 20050020524, Boyd R L. Hematopoietic stem cell gene therapy 12. U.S. Pat. No. 6,887,704. Peled T, et al. Methods of controlling proliferation and differentiation of stem and progenitor cells 13. US 20050118712, Tsai, M S. Two-stage culture protocol for isolating mesenchymal stem cells from amniotic fluid 14. US 20050042754, Miyazaki J. Induction of the formation of insulin-producing cells via gene transfer of pancreatic beta-cell-associated transcriptional factor 15. US 20050008623, Bechetoille N., et al. In vitro production of dendritic cells from CD14+ monocytes 16. US 20050095228, Fraser J K Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders 17. US Patent application 20050142118, Wernet P. Human cord blood derived unrestricted somatic stem cells (USSC) 18. US 20050059152, Tanavde V. In vitro culture of mesenchymal stem cells (MSC) and a process for the preparation thereof for therapeutic use 19. US 20040197310, Sanberg P R, et al. Compositions and methods for using umbilical cord progenitor cells in the treatment of myocardial infarction 20. Danon D, Madjar J, Edinov E, Knyszynski A, Brill S, Diamantshtein L, Shinar E. Treatment of human ulcers by application of macrophages prepared from a blood unit. Exp Gerontol. 1997 November-December; 32(6):633-41. 21. US 2004191754, Uri M. et. al. Method for Freezing Viable Cells. 22. WO 01/23532, Tsakas S., and Linardos N. Cryopreserved amniotic human cells for future therapeutic, diagnostic, genetic and other uses. 23. YU, J., LIU, J. H., PU, L. Q., CUI, X., WANG, C., OUYANG, S. L., GAO, D. Freeze-drying of Human Red Blood Cells: Influence of Carbohydrates and Their Concentrations. Cell Preservation Technology. 2004; 2(4):270-5. 24. U.S. Pat. No. 6,146,890, Danon David. Method and system for cultivating macrophages. 25. Xaio, H. H., Hua, T. C., Li, J., Gu, X. L., Wang, X., W Meng, L. R., Gao, Q. R., Chen, J., Gong, Z. P. (2004) Freeze-drying of mononuclear cells and whole blood of human cord blood. Cryoletters; 25(2):111-120. 26. Jun Lil, Tse-Chao Hual, Xue-Lian Gul, Yu Dingl, Ming Luol, Hong-Hai Xiaol, Zhi-Jiang Wu, Lv-Rong Meng, Qi-Rong Gao and Jian Chen; Morphology study of freeze-drying mononuclear cells of human cord blood. CiyoLetters 26 (3), 193-200 (2005) 27. Avigdor, A., Goichberg, P., Shivtiel, S., Dar, A., Peled, A., Samira, S., Kollet, O., Hershkovitz, R., Alon, R., Hardan, I., Ben-Hur, H., Naor, D., Nagler, A., Lapidot, T. (2004) CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow. Blood; 103(8):2981-2982. 28. Ptak, G., Clinton, M., Tischner, M., Barboni, B., Mattioli, M., Loi, P. (2002) Improving delivery and offspring viability of in vitro-produced and cloned sheep embryos. Biology of Reproduction; 67(6):1719-25. 29. WO 0201952 30. Ryan J. M. et al. (2005) Mesenchymal stem cells avoid allogeneic rejection. Journal of Inflammation 2:8; 31. Cord Blood Bank Standard Operating Procedures, Chapter 4, 05/97—Amended 07/99; https://web.emmes.com/study/cord/bld-ch04.pdf




← Previous       Next →
Advertise on FreshPatents.com - Rates & Info


You can also Monitor Keywords and Search for tracking patents relating to this Somatic cells for use in cell therapy patent application.

###


Browse recent Core Dynamics Limited patents

Keyword Monitor How KEYWORD MONITOR works... a FREE service from FreshPatents
1. Sign up (takes 30 seconds). 2. Fill in the keywords to be monitored.
3. Each week you receive an email with patent applications related to your keywords.  
Start now! - Receive info on patent apps like Somatic cells for use in cell therapy or other areas of interest.
###


Previous Patent Application:
Nucleic acid compounds for inhibiting gene expression and uses thereof
Next Patent Application:
Porous membrane device that promotes the differentiation of monocytes into dendritic cells
Industry Class:
Chemistry: molecular biology and microbiology
Thank you for viewing the Somatic cells for use in cell therapy patent info.
- - -

Results in 0.08935 seconds


Other interesting Freshpatents.com categories:
Tyco , Unilever , 3m

###

Data source: patent applications published in the public domain by the United States Patent and Trademark Office (USPTO). Information published here is for research/educational purposes only. FreshPatents is not affiliated with the USPTO, assignee companies, inventors, law firms or other assignees. Patent applications, documents and images may contain trademarks of the respective companies/authors. FreshPatents is not responsible for the accuracy, validity or otherwise contents of these public document patent application filings. When possible a complete PDF is provided, however, in some cases the presented document/images is an abstract or sampling of the full patent application for display purposes. FreshPatents.com Terms/Support
-g2-0.1577

66.232.115.224
Browse patents:
Next
Prev

stats Patent Info
Application #
US 20100105133 A1
Publish Date
04/29/2010
Document #
File Date
12/31/1969
USPTO Class
Other USPTO Classes
International Class
/
Drawings
0


Cell Therapy

Follow us on Twitter
twitter icon@FreshPatents

Core Dynamics Limited


Browse recent Core Dynamics Limited patents



Chemistry: Molecular Biology And Microbiology   Animal Cell, Per Se (e.g., Cell Lines, Etc.); Composition Thereof; Process Of Propagating, Maintaining Or Preserving An Animal Cell Or Composition Thereof; Process Of Isolating Or Separating An Animal Cell Or Composition Thereof; Process Of Preparing A Composition Containing An Animal Cell; Culture Media Therefore   Primate Cell, Per Se   Human  

Browse patents:
Next
Prev
20100429|20100105133|somatic cells for use in cell therapy|The present invention generally concerns cell therapy and products for use in such therapy. Particularly, the invention provides a preserved cell preparation essentially free of one or more members of a group of cryoprotecting agents consisting of polyalcohols, DMSO and cryoprotecting proteins, the preserved cell preparation comprising somatic cells and |Core-Dynamics-Limited
';