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Novel polymorphs of azabicyclohexane




Title: Novel polymorphs of azabicyclohexane.
Abstract: The invention provides polymorphic crystalline forms of acid addition salts of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane designated as polymorph form A, polymorph form B and polymorph form C, where polymorph form A is more thermodynamically stable than the other forms, methods for preparing and using such polymorph forms and pharmaceutical compositions containing such polymorph forms. ...


USPTO Applicaton #: #20090326245
Inventors: Eric J. Hagen, Kevin Halloran


The Patent Description & Claims data below is from USPTO Patent Application 20090326245, Novel polymorphs of azabicyclohexane.




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Organic compounds -- part of the class 532-570 series
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stats Patent Info
Application #
US 20090326245 A1
Publish Date
12/31/2009
Document #
12428399
File Date
04/22/2009
USPTO Class
548515
Other USPTO Classes
International Class
07D209/52
Drawings
0


Crystal Paring Pharmaceutical Compositions Polymorphic Thermodynamic

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Organic Compounds -- Part Of The Class 532-570 Series   Azo Compounds Containing Formaldehyde Reaction Product As The Coupling Component   Carbohydrates Or Derivatives   Hetero Ring Is Five-membered Consisting Of One Nitrogen And Four Carbons (e.g., Halopyrrolidines, Etc.)   Polycyclo Ring System Having The Five-membered Hetero Ring As One Of The Cyclos   Bicyclo Ring System Having The Five-membered Hetero Ring As One Of The Cyclos (e.g., Octahydroindoles, Etc.)   The Ring Nitrogen Is Bonded Directly To Two Ring Carbons Of The Same Cyclo Which Carbons Are Members Of One Cyclo Only (e.g., Cyclopenta(c)pyrroles, Etc.)  

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20091231|20090326245|novel polymorphs of azabicyclohexane|The invention provides polymorphic crystalline forms of acid addition salts of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane designated as polymorph form A, polymorph form B and polymorph form C, where polymorph form A is more thermodynamically stable than the other forms, methods for preparing and using such polymorph forms and pharmaceutical compositions containing such polymorph |
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