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Small interfering rnas that efficiently inhibit viral expression and methods of use thereof   

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Abstract: The invention provides methods, compositions, and kits comprising small interfering RNA (shRNA or siRNA) which are useful for inhibition of viralmediated gene expression. Small interfering RNAs as described herein may be used in methods of treatment of HCV infection. ShRNA and siRNA constructs that target the internal ribosome entry site (IRES) sequence of HCV are described. ...


USPTO Applicaton #: #20090170794 - Class: 514 44 (USPTO) - 07/02/09 - Class 514 
Related Terms: Ribosome   ShRNA   
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The Patent Description & Claims data below is from USPTO Patent Application 20090170794, Small interfering rnas that efficiently inhibit viral expression and methods of use thereof.

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