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05/07/09 - USPTO Class 606 |  1 views | #20090118726 | Prev - Next | About this Page  606 rss/xml feed  monitor keywords

Systems and methods for transeptal cardiac procedures, including tissue sealing members associated methods

USPTO Application #: 20090118726
Title: Systems and methods for transeptal cardiac procedures, including tissue sealing members associated methods
Abstract: Systems and methods for transeptal cardiac procedures are disclosed. A patient treatment device in accordance with a particular embodiment includes a catheter having a proximal end, a distal end, a working portion toward the distal end, and an electrical energy path coupleable to a source of electrical energy. The device can further include a tissue penetrating member carried by the catheter and an electrode device carried by the working portion of the catheter and movable along the tissue penetrating member. The electrode device can include a collapsible stranded conductive material coupled to the electrical signal path and being changeable between a deployed position and a stowed position. The conductive material can be elongated along a deployment axis when in the stowed position, and can be contracted along the deployment axis and expanded transverse to the deployment axis when in the deployed position. (end of abstract)



Agent: Perkins Coie LLP Patent-sea - Seattle, WA, US
Inventors: David C. Auth, Ryan E. Kaveckis, Larry B. Kulesa, Joseph E. Eichinger, David A. Herrin, Mark A. Tempel, Robert S. Schwartz
USPTO Applicaton #: 20090118726 - Class: 606 33 (USPTO)

Systems and methods for transeptal cardiac procedures, including tissue sealing members associated methods description/claims


The Patent Description & Claims data below is from USPTO Patent Application 20090118726, Systems and methods for transeptal cardiac procedures, including tissue sealing members associated methods.

Brief Patent Description - Full Patent Description - Patent Application Claims
  monitor keywords CROSS-REFERENCE TO RELATED APPLICATION

The present application claims priority to U.S. Provisional Application No. 60/977,837, filed Oct. 5, 2007 and incorporated herein by reference.

TECHNICAL FIELD

The present disclosure is directed generally to systems and methods for transeptal cardiac procedures, including separable guidewires, tissue penetrating members, and tissue sealing members.

BACKGROUND

The human heart is a complex organ that requires reliable, fluid-tight seals to prevent de-oxygenated blood and other constituents received from the body\'s tissues from mixing with re-oxygenated blood delivered to the body\'s tissues. FIG. 1A illustrates a human heart 100 having a right atrium 101, which receives the de-oxygenated blood from the superior vena cava 116 and the inferior vena cava 104. The de-oxygenated blood passes to the right ventricle 103, which pumps the de-oxygenated blood to the lungs via the pulmonary artery 114. Re-oxygenated blood returns from the lungs to the left atrium 102 and is pumped into the left ventricle 105. From the left ventricle 105, the re-oxygenated blood is pumped throughout the body via the aorta 115.

The right atrium 101 and the left atrium 102 are separated by an interatrial septum 106. As shown in FIG. 1B, the interatrial septum 106 includes a primum 107 and a secundum 108. Prior to birth, the primum 107 and the secundum 108 are separated to form an opening (the foramen ovale 109) that allows blood to flow from the right atrium 101 to the left atrium 102 while the fetus receives oxygenated blood from the mother. After birth, the primum 107 normally seals against the secundum 108 and forms an oval-shaped depression, i.e., a fossa ovalis 110.

In some infants, the primum 107 never completely seals with the secundum 108, as shown in cross-sectional view in FIG. 1C and in a left side view in FIG. 1D. In these instances, a patency often having the shape of a tunnel 112 forms between the primum 107 and the secundum 108. This patency is typically referred to as a patent foramen ovale or PFO 113. In most circumstances, the PFO 113 will remain functionally closed and blood will not tend to flow through the PFO 113, due to the normally higher pressures in the left atrium 102 that secure the primum 107 against the secundum 108. Nevertheless, during physical exertion or other instances when pressures are greater in the right atrium 101 than in the left atrium 102, blood can inappropriately pass directly from the right atrium 101 to the left atrium 102 and can carry with it clots, gas bubbles, or other vaso-active substances. Such constituents in the atrial system can pose serious health risks including hemodynamic problems, cryptogenic strokes, venous-to-atrial gas embolisms, migraines, and in some cases even death.

Traditionally, open chest surgery was required to suture or ligate a PFO 113. However, these procedures carry high attendant risks, such as postoperative infection, long patient recovery, and significant patient discomfort and trauma. Accordingly, less invasive techniques have been developed. Most such techniques include using transcatheter implantation of various mechanical devices to close the PFO 113. Such devices include the Cardia® PFO Closure Device, Amplatzer® PFO Occluder, and CardioSEAL® Septal Occlusion Device. One potential drawback with these devices is that they may not be well suited for the long, tunnel-like shape of the PFO 113. As a result, the implanted mechanical devices may become deformed or distorted and in some cases may fail, migrate, or even dislodge. Furthermore, these devices can irritate the cardiac tissue at or near the implantation site, which in turn can potentially cause thromboembolic events, palpitations, and arrhythmias. Other reported complications include weakening, erosion, and tearing of the cardiac tissues around the implanted devices.

Another potential drawback with the implanted mechanical devices described above is that, in order to be completely effective, the tissue around the devices must endothelize once the devices are implanted. The endothelization process can be gradual and can accordingly take several months or more to occur. Accordingly, the foregoing techniques do not immediately solve the problems caused by the PFO 113.

Still another drawback associated with the foregoing techniques is that they can be technically complicated and cumbersome. Accordingly, the techniques may require multiple attempts before the mechanical device is appropriately positioned and implanted. As a result, implanting these devices may require long procedure times during which the patient must be kept under conscious sedation, which can pose further risks to the patient.

BRIEF DESCRIPTION OF THE DRAWINGS

FIGS. 1A-1D illustrate a human heart having a patent foramen ovale (PFO) in accordance with the prior art.

FIG. 2 illustrates a catheter positioned proximate to a PFO for treatment in accordance with several embodiments of the disclosure.

FIGS. 3A-3J illustrate a process for closing a PFO in accordance with an embodiment of the disclosure.

FIG. 4 is a partially schematic, isometric illustration of a process for closing a PFO via a trans-primum procedure in accordance with an embodiment of the disclosure.

FIGS. 5A-5D are schematic, isometric illustrations of a process for closing a PFO using a trans-primum procedure in accordance with another embodiment of the disclosure.

FIGS. 6A-6M illustrate guidewires configured to center in a PFO tunnel in accordance with embodiments of the disclosure.



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Previous Patent Application:
Hemostatic tissue tunnel generator for inserting treatment apparatus into tissue of a patient
Next Patent Application:
Ablation devices and methods of using the same
Industry Class:
Surgery

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