| Medicament for treatment of non-insulin dependent diabetes mellitus, hypertension and/or metabolic syndrome -> Monitor Keywords |
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Medicament for treatment of non-insulin dependent diabetes mellitus, hypertension and/or metabolic syndromeMedicament for treatment of non-insulin dependent diabetes mellitus, hypertension and/or metabolic syndrome description/claimsThe Patent Description & Claims data below is from USPTO Patent Application 20080318866, Medicament for treatment of non-insulin dependent diabetes mellitus, hypertension and/or metabolic syndrome. Brief Patent Description - Full Patent Description - Patent Application Claims This application is a continuation of U.S. application Ser. No. 10/933,297 filed Sep. 3, 2004, which is a division of Ser. No. 10/210,737 filed Jul. 31, 2002, which is a continuation of PCT/DK01/00075 filed Feb. 1, 2001. The prior applications set forth above are hereby incorporated by reference in their entirety. TECHNICAL FIELDThe present invention relates to a new medicament for the treatment of non-insulin dependent diabetes mellitus, hypertension, metabolic syndromes and other conditions in mammals. BACKGROUND ARTDiabetes is a common disease that has a prevalence of 2-4% in the population. Non-insulin dependent diabetes mellitus comprises about 85% of diabetes most commonly occurring at the age above 40 years. The incidence of non-insulin dependent diabetes mellitus is increasing and is at a global level expected to surpass 200 million subjects at year 2010. Diabetes is associated with increased morbidity and a 2-4-fold increase in mortality primarily due to cardiovascular Non-insulin dependent diabetes mellitus develops especially in subjects with insulin resistance and a cluster of cardiovascular risk factor's such as obesity, hypertension and dyslipidemia, a syndrome which first recently has been recognized and is named “The metabolic syndrome” (Alberti K. G., Zimmet P. Z.; Definition, diagnosis and classification of diabetes mellitus and its complications”. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet. Med. 1998 July; 15(7), p. 529-53). In accordance with the WHO-definition (www.idi.org.au/whoreport.htm), a patient has metabolic syndrome if insulin resistance and/or glucose intolerance is present together with two or more of the following conditions: reduced glucose tolerance or diabetes insulin sensitivity (under hyperinsulinaemic, euglycaemic conditions corresponding to a glucose uptake below the lower quartile for the background population) increased blood pressure (≧140/90 mmHg) increased plasma triglyceride (≧1.7 mmol/l) and/or low HDL cholesterol (<0.9 mmol/l for men; < 1.0 mmol/l for women) central adipositas (waist/hip ratio for men: >0.90 and for women >0.85) and/or Body Mass Index >30 kg/m2) micro albuminuria (urine albumin excretion: ≧20 μg min−1 or albumin/creatinine ratio ≧2.0 mg/mmol. Continue reading about Medicament for treatment of non-insulin dependent diabetes mellitus, hypertension and/or metabolic syndrome... 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